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公开(公告)号：US20210161097A1
公开(公告)日：2021-06-03
申请号：US17047238
申请日：2018-10-23
申请人： Hyun Jeong KIM
发明人： Hyun Jeong KIM
摘要： Provide is a storage apparatus for a companion animal, including a first storage part in which a companion animal is seated, a second storage part connected to an edge of the first storage part and configured to surround the companion animal, and a third storage part coupled to the second storage part, wherein the third storage part surrounds the first storage part or is turned over to cover an upper side of the second storage part, thereby allowing the companion animal to be stored in the storage apparatus having a house or bag form.
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公开(公告)号：US08926334B2
公开(公告)日：2015-01-06
申请号：US13576428
申请日：2011-01-27
申请人： Se Hyung Park , Lae Hyun Kim , Seung Jae Shin , Deuk Hee Lee , Wan Joo Park , Hyun Chul Cho , Hyun Jeong Kim
发明人： Se Hyung Park , Lae Hyun Kim , Seung Jae Shin , Deuk Hee Lee , Wan Joo Park , Hyun Chul Cho , Hyun Jeong Kim
CPC分类号： A61M5/46 , G09B23/285
摘要： Provided is an injection simulation system and method. The system includes a syringe comprising an injection needle, a haptic unit which measures an insertion angle and insertion depth of the injection needle, and which comprises a motor unit that is driven by a haptic force corresponding to the measured insertion angle and insertion depth. The system also includes a control unit which calculates the haptic force corresponding to the insertion angle and the insertion depth, and transmits the calculated haptic force to the motor unit of the haptic unit.
摘要翻译： 提供了一种注射模拟系统和方法。 该系统包括注射器，其包括注射针，测量注射针的插入角度和插入深度的触觉单元，并且包括由对应于测量的插入角度和插入深度的触觉力驱动的马达单元。 该系统还包括控制单元，其计算与插入角度和插入深度相对应的触觉力，并将计算出的触觉力传递到触觉单元的电动机单元。
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公开(公告)号：US08673856B2
公开(公告)日：2014-03-18
申请号：US12513182
申请日：2007-11-02
申请人： Jae II Kim , Hye Whon Rhim , Hyun Jeong Kim , Hong Won Suh , Soung Hun Roh , Jung A Yun , Seung Kyu Lee , Young Jae Eu , Heung Sik Na
发明人： Jae II Kim , Hye Whon Rhim , Hyun Jeong Kim , Hong Won Suh , Soung Hun Roh , Jung A Yun , Seung Kyu Lee , Young Jae Eu , Heung Sik Na
CPC分类号： C07K14/43504 , A61K38/00
摘要： The present invention relates to a method for increasing the binding reversibility of a ω-conotoxin to a N-type calcium channel, which comprises preparing a ω-conotoxin having a Ile and/or Ala residue at a position of amino acid (11 and/or 12), respectively in the second loop between cysteine residues (2 and 3) of the ω-conotoxin represented by the formula I, such that the prepared ω-conotoxin has the increased binding reversibility to N-type calcium channel. In addition, the present invention relates to a novel ω-conotoxin and a pharmaceutical composition having plausible properties in view of blocking activity to and specificity to N-type calcium channel, and dramatically improved binding reversibility to N-type calcium channel.
摘要翻译： 本发明涉及一种增加ω-芋螺毒素与N型钙通道的结合可逆性的方法，其包括在氨基酸（11和/或其氨基酸）的位置制备具有Ile和/或Ala残基的ω-芋螺毒素， 或12）分别在由式I表示的ω-芋螺毒素的半胱氨酸残基（2和3）之间的第二环中，使得所制备的ω-芋螺毒素具有增加的对N-型钙通道的结合可逆性。 此外，本发明涉及一种新型的ω-芋螺毒素和具有似乎合理的性质的药物组合物，其特征在于阻断N-型钙通道的活性和特异性，并显着提高了对N-型钙通道的结合可逆性。
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公开(公告)号：US20130049572A1
公开(公告)日：2013-02-28
申请号：US13592155
申请日：2012-08-22
申请人： Hyuk-Hwan KIM , Si-Ki PARK , Young-Min PARK , Hyun-Jeong KIM
发明人： Hyuk-Hwan KIM , Si-Ki PARK , Young-Min PARK , Hyun-Jeong KIM
CPC分类号： G02F1/133615 , G02B6/0023 , G02B6/0073 , G02F1/133617 , G02F2001/133624
摘要： A backlight assembly includes a light emitting portion, a chromaticity converter and a light guide plate. The light emitting portion generates a first light. The chromaticity converter receives the first light, and converts a chromaticity of the first light to generate a uniform light having a uniform chromaticity. The light guide plate includes an incident surface to which the uniform light is incident, and a light exiting surface guiding the uniform light provided from the incident surface and emitting the uniform light. Accordingly, a display quality of a display apparatus may be enhanced.
摘要翻译： 背光组件包括发光部分，色度转换器和导光板。 发光部分产生第一光。 色度转换器接收第一光，并且转换第一光的色度以产生具有均匀色度的均匀光。 导光板包括入射表面，均匀光入射到入射面，以及光出射面，引导从入射面提供的均匀光并发出均匀的光。 因此，可以提高显示装置的显示质量。
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公开(公告)号：US20120301858A1
公开(公告)日：2012-11-29
申请号：US13576428
申请日：2011-01-27
申请人： Se Hyung Park , Lae Hyun Kim , Seung Jae Shin , Deuk Hee Lee , Wan Joo Park , Hyun Chul Cho , Hyun Jeong Kim
发明人： Se Hyung Park , Lae Hyun Kim , Seung Jae Shin , Deuk Hee Lee , Wan Joo Park , Hyun Chul Cho , Hyun Jeong Kim
CPC分类号： A61M5/46 , G09B23/285
摘要： Provided is an injection simulation system and method. The system includes a syringe comprising an injection needle, a haptic unit which measures an insertion angle and insertion depth of the injection needle, and which comprises a motor unit that is driven by a haptic force corresponding to the measured insertion angle and insertion depth. The system also includes a control unit which calculates the haptic force corresponding to the insertion angle and the insertion depth, and transmits the calculated haptic force to the motor unit of the haptic unit.
摘要翻译： 提供了一种注射模拟系统和方法。 该系统包括注射器，其包括注射针，测量注射针的插入角度和插入深度的触觉单元，并且包括由对应于测量的插入角度和插入深度的触觉力驱动的马达单元。 该系统还包括控制单元，其计算与插入角度和插入深度相对应的触觉力，并将计算出的触觉力传递到触觉单元的电动机单元。
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公开(公告)号：US20100056456A1
公开(公告)日：2010-03-04
申请号：US12513182
申请日：2007-11-02
申请人： Jae Il Kim , Hye Whon Rhim , Hyun Jeong Kim , Hong Won Suh , Soung Hun Roh , Jung A. Yun , Seung Kyu Lee , Young Jae Eu , Heung Sik Na
发明人： Jae Il Kim , Hye Whon Rhim , Hyun Jeong Kim , Hong Won Suh , Soung Hun Roh , Jung A. Yun , Seung Kyu Lee , Young Jae Eu , Heung Sik Na
CPC分类号： C07K14/43504 , A61K38/00
摘要： The present invention relates to a method for increasing the binding reversibility of a ω-conotoxin to a N-type calcium channel, which comprises preparing a ω-conotoxin having a Ile and/or Ala residue at a position of amino acid (11 and/or 12), respectively in the second loop between cysteine residues (2 and 3) of the ω-conotoxin represented by the formula I, such that the prepared ω-conotoxin has the increased binding reversibility to N-type calcium channel. In addition, the present invention relates to a novel ω-conotoxin and a pharmaceutical composition having plausible properties in view of blocking activity to and specificity to N-type calcium channel, and dramatically improved binding reversibility to N-type calcium channel.
摘要翻译： 本发明涉及一种增加ω-芋螺毒素与N-型钙通道的结合可逆性的方法，其包括在氨基酸（11和/或其氨基酸）的位置制备具有Ile和/或Ala残基的ω-芋螺毒素， 或12）分别在由式I表示的ω-芋螺毒素的半胱氨酸残基（2和3）之间的第二环中，使得制备的ω-芋螺毒素对N-型钙通道具有增加的结合可逆性。 此外，本发明涉及一种新型的ω-芋螺毒素和具有似乎合理的性质的药物组合物，其特征在于阻断N-型钙通道的活性和特异性，并显着提高了与N-型钙通道的结合可逆性。
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公开(公告)号：US20090030181A1
公开(公告)日：2009-01-29
申请号：US11547730
申请日：2004-12-29
申请人： Kyou-Hoon Han , Seung-Wook Chi , Hyun-Jeong Kim , Si-Hyung Lee , Min-Jung Ahn , Do-Hyoung Kim , Jae-Sung Kim , Shin-Ae Park
发明人： Kyou-Hoon Han , Seung-Wook Chi , Hyun-Jeong Kim , Si-Hyung Lee , Min-Jung Ahn , Do-Hyoung Kim , Jae-Sung Kim , Shin-Ae Park
CPC分类号： C07K14/4746
摘要： Disclosed are peptides for inhibiting mdm2 (mouse double minute 2) and a pharmaceutical composition comprising the same.
摘要翻译： 公开了抑制mdm2（小鼠双倍分子2）的肽和包含其的药物组合物。
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28.发明申请Composition Comprising an Extract of Gramineae Plant for the Prevention and Treatment of Ischemic Diseases and Degenerative Brain Diseases and the Use Thereof 审中-公开包含禾本科植物提取物的组合物，用于预防和治疗缺血性疾病和退行性脑疾病及其应用公开(公告)号：US20080113005A1
公开(公告)日：2008-05-15
申请号：US11813285
申请日：2006-01-04
申请人： Jong Won Lee , Ki-Chul Hwang , Hyung Soo Han , Sun Ha Lim , Hyeong-Kyu Lee , Sang Hyuk Lee , Kyu Won Kim , Hyung Oh Jun , Hyun Jeong Kim , In-Seon Lee , Chae Ha Yang
发明人： Jong Won Lee , Ki-Chul Hwang , Hyung Soo Han , Sun Ha Lim , Hyeong-Kyu Lee , Sang Hyuk Lee , Kyu Won Kim , Hyung Oh Jun , Hyun Jeong Kim , In-Seon Lee , Chae Ha Yang
IPC分类号： A61K36/899 , A61K9/00 , A61P25/28
CPC分类号： A61K36/899 , A23L33/105 , A23V2002/00 , A23V2200/322 , A23V2250/21
摘要： The present invention relates to a composition comprising extracts of Gramineae plant that improves cell viability under hypoxic conditions by inhibiting apoptosis. Thus, the extract of Triticum aestivum L., one of the Gramineae plant, of the present invention, in particular, prevents damage of brain, heart and kidney in animal models of ischemic diseases, and it also improves memory in an animal model of Alzheimer's disease. Therefore, a composition comprising extracts of Gramineae can be used as therapeutic agents or health care foods for preventing and treating ischemic diseases and degenerative brain diseases.
摘要翻译： 本发明涉及包含通过抑制细胞凋亡在缺氧条件下改善细胞活力的禾本科植物提取物的组合物。 因此，特别地，本发明的禾本科植物之一的小麦Triticum aestivum L.的提取物防止脑，心脏和肾脏在缺血性疾病的动物模型中的损伤，并且还改善了阿尔茨海默病动物模型中的记忆 疾病。 因此，包含禾本科植物提取物的组合物可用作预防和治疗缺血性疾病和退行性脑疾病的治疗剂或保健食品。
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