Method For Preparing Kaempferol-3-0-Rutinoside and Composition of Skin External Application Comprising Thereof
    21.
    发明申请
    Method For Preparing Kaempferol-3-0-Rutinoside and Composition of Skin External Application Comprising Thereof 审中-公开
    制备山奈酚3-0-鲁替苷的方法及其皮肤外用剂组成

    公开(公告)号:US20100113372A1

    公开(公告)日:2010-05-06

    申请号:US12445362

    申请日:2007-04-25

    IPC分类号: A61K31/70 C12P19/60

    CPC分类号: C12P19/60

    摘要: Disclosed is a method for the preparation of kaempferol-3-O-rutinoside and a composition of a skin external application comprising kaempferol-3-O-rutinoside as an active ingredient. The method for isolating kaempferol-3-O-rutinoside through hydrolysis uses an enzyme or microbe that removes the sugar selectively from kaempferol-3-O-rutinoside glycosides in a plant extract. Disclosed also is a composition of a skin external application comprising kaempferol-3-O-rutinoside that prevents skin wrinkle.

    摘要翻译: 本发明公开了山奈酚-3-O-芸香糖苷的制备方法以及含有山奈酚-3-O-芸香糖苷作为活性成分的外用皮肤组合物。 通过水解分离山奈酚-3-O-芸香糖苷的方法使用从植物提取物中的山奈酚-3-O-芸香糖苷糖苷中选择性除去糖的酶或微生物。 还公开了一种皮肤外用剂的组合物,其包含防止皮肤皱纹的山奈酚-3-O-芸香糖苷。

    Percutaneous controlled releasing material using nano-sized polymer particles and external application agent containing the same
    23.
    发明申请
    Percutaneous controlled releasing material using nano-sized polymer particles and external application agent containing the same 审中-公开
    使用纳米尺寸聚合物颗粒的经皮控制释放材料和含有其的外用施用剂

    公开(公告)号:US20090232855A1

    公开(公告)日:2009-09-17

    申请号:US09878712

    申请日:2001-06-11

    IPC分类号: A61K8/02 A61K9/14

    CPC分类号: A61K9/5138

    摘要: A percutaneous releasing material and agent having characteristics that include a high stability of an active agent in the formulation, a high topical absorption rate, decreased irritation on the skin, and an increased tactile comfort. The percutaneous releasing material incorporates an external application agent composition that is prepared by using nanometer-sized polymer particles, i.e., particles having a size or diameter between approximately 1 nm and approximately 500 nm, and more preferably having a size between about 30 nm and about 150 nm. Further, the percutaneous releasing material and agent according to the present invention incorporate polymer particles that preferably contain a physiologically active agent that more readily penetrates through the stratum corneum to the upper layer of the dermis, whereby the physiologically active agent is effused into the skin while staying in the upper layer of dermis.

    摘要翻译: 具有包含制剂中活性剂高稳定性,高局部吸收率,对皮肤刺激性降低以及增加的触觉舒适度的特征的经皮释放材料和试剂。 经皮释放材料包含通过使用纳米尺寸聚合物颗粒制备的外用施用剂组合物,即具有约1nm至约500nm之间的尺寸或直径的颗粒,更优选具有约30nm至约30nm的尺寸 150nm。 此外,根据本发明的经皮释放材料和试剂掺入优选含有更容易穿透角质层至生理活性剂的生物活性剂的聚合物颗粒,从而使生理活性剂流入皮肤,同时 留在真皮层的上层。

    Cosmetic composition containing hydrolysates of icariin
    27.
    发明授权
    Cosmetic composition containing hydrolysates of icariin 有权
    含有淫羊藿苷水解物的化妆品组合物

    公开(公告)号:US08394775B2

    公开(公告)日:2013-03-12

    申请号:US12095654

    申请日:2006-10-30

    IPC分类号: A61K8/60 A61Q19/08

    摘要: The present invention relates to a cosmetic composition containing hydrolysates of icariin, and more particularly, a cosmetic composition containing hydrolysates of icariin including icaritin, icariside I and icariside II. The hydrolysates of icariin is prepared by a method comprising the steps of: (a) obtaining an extract from a plant containing icariin using water or an organic solvent; and (b) hydrolyzing the plant extract with an acid, a base, an enzyme or a microorganism producing the enzyme. The cosmetic composition according to the present invention is employed for anti-oxidant, anti-aging, whitening or anti-wrinkling effects.

    摘要翻译: 本发明涉及含有淫羊藿苷的水解物的化妆品组合物,更具体地说,涉及包含淫羊藿苷,吡螨苷I和鸢尾苷II的淫羊藿苷的水解物的化妆品组合物。 淫羊The苷的水解物是通过包括以下步骤的方法制备的:(a)使用水或有机溶剂从含有淫羊藿苷的植物中获得提取物; 和(b)用产生该酶的酸,碱,酶或微生物水解植物提取物。 根据本发明的化妆品组合物用于抗氧化,抗衰老,增白或起皱作用。

    COSMETIC COMPOSITION CONTAINING HYDROLYSATES OF ICARIIN
    29.
    发明申请
    COSMETIC COMPOSITION CONTAINING HYDROLYSATES OF ICARIIN 有权
    含有ICARIIN水解物的化妆品组合物

    公开(公告)号:US20090170787A1

    公开(公告)日:2009-07-02

    申请号:US12095654

    申请日:2006-10-30

    IPC分类号: A61K8/60 A61Q19/08

    摘要: The present invention relates to a cosmetic composition containing hydrolysates of icariin, and more particularly, a cosmetic composition containing hydrolysates of icariin including icaritin, icariside I and icariside II. The hydrolysates of icariin is prepared by a method comprising the steps of: (a) obtaining an extract from a plant containing icariin using water or an organic solvent; and (b) hydrolyzing the plant extract with an acid, a base, an enzyme or a microorganism producing the enzyme. The cosmetic composition according to the present invention is employed for anti-oxidant, anti-aging, whitening or anti-wrinkling effects.

    摘要翻译: 本发明涉及含有淫羊藿苷的水解物的化妆品组合物,更具体地说,涉及包含淫羊藿苷,吡螨苷I和鸢尾苷II的淫羊藿苷的水解物的化妆品组合物。 淫羊The苷的水解物是通过包括以下步骤的方法制备的:(a)使用水或有机溶剂从含有淫羊藿苷的植物中获得提取物; 和(b)用产生该酶的酸,碱,酶或微生物水解植物提取物。 根据本发明的化妆品组合物用于抗氧化,抗衰老,增白或起皱作用。