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    METHODS FOR MAKING RECOMBINANT PROTEIN
    21.
    发明申请
    METHODS FOR MAKING RECOMBINANT PROTEIN 有权

    公开(公告)号：US20220267751A1

    公开(公告)日：2022-08-25

    申请号：US17626168

    申请日：2020-07-10

    Applicant: Monash University

    Inventor： James Whisstock ,  Ruby Law ,  Adam Quek ,  Paul Conroy

    IPC: C12N9/68 ,  C07K14/81

    Abstract: The present invention relates to methods of producing recombinant plasminogen in a mammalian expression system. A method for producing plasminogen, the method comprising (i) providing a host cell comprising a first recombinant polynucleotide encoding plasminogen and a second recombinant polynucleotide encoding a plasminogen activation inhibitor; (ii) culturing said host cell in a suitable culture medium under conditions to effect expression of plasminogen from the first polynucleotide and plasminogen activation inhibitor from the second polynucleotide.

    VISIBLE LIGHT POSITIONING RECEIVER ARRANGEMENT AND TWO STAGE POSITIONING METHOD
    25.
    发明申请
    VISIBLE LIGHT POSITIONING RECEIVER ARRANGEMENT AND TWO STAGE POSITIONING METHOD 有权

    公开(公告)号：US20210325505A1

    公开(公告)日：2021-10-21

    申请号：US17253607

    申请日：2019-05-30

    Applicant: MONASH UNIVERSITY

    Inventor： Stefanie Cincotta ,  Adrian Neild ,  Jean Armstrong

    IPC: G01S5/16 ,  H04B10/116 ,  G01S1/70

    Abstract: A visible light positioning receiver arrangement for obtaining spatial position information of the receiver arrangement from a plurality of luminaires (5), at least one of the luminaires including at least one associated modulated light source for transmitting a light signal providing positional information of one or more reference points associated with the luminaire, said receiver arrangement including: an imaging receiver for capturing an image of the luminaires and associated said reference point(s); and a non-imaging receiver (7) for estimating an angle of arrival (AOA) of light from each said modulated light source, and for decoding the reference point positional information therefrom; wherein said AOA information and reference point positional information from the non-imaging receiver is matched to the image captured by the imaging receiver to obtain said spatial position information.

    TRANSCRANIAL STIMULATION WITH REAL-TIME MONITORING
    26.
    发明申请
    TRANSCRANIAL STIMULATION WITH REAL-TIME MONITORING 有权

    公开(公告)号：US20210299447A1

    公开(公告)日：2021-09-30

    申请号：US17346971

    申请日：2021-06-14

    Applicant: MONASH UNIVERSITY

    Inventor： Paul B FITZGERALD ,  Caley M. Sullivan ,  Richard H. THOMSON

    IPC: A61N1/36 ,  A61B5/00 ,  A61B5/369 ,  A61B5/375

    Abstract: Closed-loop transcranial stimulation and monitoring is disclosed that includes generating a stimulation signal having a set of first oscillation parameters; applying the stimulation signal transcranially to a patient; monitoring the stimulation signal as applied to the patient; receiving a brain activity signal from the patient; generating a feedback signal based on the monitored stimulation signal as applied to the patient; and generating a modified activity signal by subtracting the feedback signal from the brain activity signal; determining one or more second oscillation parameters of the modified activity signal; and adjusting the set of first oscillation parameters of the stimulation signal based on the one or more second oscillation parameters of the modified activity signal. Closed-loop transcranial stimulation and monitoring is also disclosed in which the patient is engaged in a cognitive task.

    Method and System for Quality Assurance and Control of Additive Manufacturing Process
    29.
    发明申请
    Method and System for Quality Assurance and Control of Additive Manufacturing Process 有权

    公开(公告)号：US20210078076A1

    公开(公告)日：2021-03-18

    申请号：US16611897

    申请日：2018-05-10

    Applicant: Monash University

    Inventor： Marten Jurg ,  Andrey Molotnikov

    IPC: B22F3/105 ,  B33Y10/00

    Abstract: An additive manufacturing system and method is provided for fabricating 3D objects (16) from successive layers (14) of material. The additive manufacturing system (10) has an energy projection assembly (20) for inputting energy (22) into a specified area within the layer (18) to consolidate the material; a plurality of image sensors (30, 32, 34), each of the image sensors having a corresponding field of view (35, 40, 42) covering at least part of the layer (18) of material, such that each of the fields of view at least partially overlap with the field of view of at least one other of the image sensors; and an image processor (56) to capture image data from each of the image sensors (30, 32, 34). The image processor (56) controls exposure times for each of the image sensors (30, 32, 34) and combines the image data from the image sensors to provide a single, spatially resolved image of the energy being input throughout the specified area for each layer (14) of material respectively for comparison against threshold data values to locate potential consolidation defects in the specified area.

    IMPROVED HEAT TREATABLE TITANIUM ALLOY
    30.
    发明申请
    IMPROVED HEAT TREATABLE TITANIUM ALLOY 审中-公开

    公开(公告)号：US20200291502A1

    公开(公告)日：2020-09-17

    申请号：US16753480

    申请日：2018-10-08

    Applicant: MONASH UNIVERSITY

    Inventor： Xinhua WU ,  Xigen ZHOU

    IPC: C22C14/00 ,  C22F1/18 ,  F16B31/06

    Abstract: A “modified” meta-stable # titanium alloy that, apart from carbon content, corresponds to the composition range for standard Beta-C titanium alloy. The modified alloy comprises vanadium, chromium, molybdenum, zirconium, aluminium, with maxima for oxygen, iron, nitrogen, hydrogen, yttrium, and other elements (apart from carbon and titanium), with a balance (apart from carbon) of titanium. The modified alloy has carbon present at a stable total carbon level sufficiently in excess of 0.05 wt. % achieving an improvement in the mechanical properties of UTS, DSS and fatigue strength in threaded regions, relative to standard Beta-C alloy with a specified carbon level below 0.05 wt. %, with a maximum carbon content controlled so as to preclude carbide formation having a detrimental effect on the level of fatigue strength.

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