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21.
公开(公告)号:US20170173111A1
公开(公告)日:2017-06-22
申请号:US15413991
申请日:2017-01-24
Inventor: Shira TOLEDANO , Ofra Kessler , Gera Neufeld , Yoreh Barak , Yelena Mumblat
CPC classification number: A61K38/1709 , A61K9/0048 , A61K45/06
Abstract: The present invention relates, according to some embodiments, method of treating eye diseases, such as AMD by administering Semaphorin 3C (Sema3C) or a variant thereof having amino acid modifications at furin-like pro-protein convertase cleavage sites, rendering these sites resistant to cleavage.
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公开(公告)号:US20240352484A1
公开(公告)日:2024-10-24
申请号:US18638775
申请日:2024-04-18
Inventor: Asya ROLLS , Lior GEPSTEIN , Hedva HAYKIN , Hilla AZULAY-DEBBY
CPC classification number: C12N15/86 , A61B5/055 , C12N2750/14143
Abstract: Provided is reward system activation for therapeutic purposes. Accordingly there is provided a method of treating a disease in a subject in need thereof, the method comprising subjecting the subject to a treatment module which activates the reward system of the subject.
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公开(公告)号:US20240304200A1
公开(公告)日:2024-09-12
申请号:US18276171
申请日:2022-02-08
Applicant: RAMBAM MED-TECH LTD. , BAR-ILAN UNIVERSITY
Inventor: Joseph KESHET , Talia BEN-SIMON , Felix KREUK , Jacob T. COHEN , Faten AWWAD
IPC: G10L21/007 , G10L15/04
CPC classification number: G10L21/007 , G10L15/04
Abstract: A system and method of speech modification may include: receiving a recorded speech, comprising one or more phonemes uttered by a speaker; segmenting the recorded speech to one or more phoneme segments (PS), each representing an uttered phoneme; selecting a phoneme segment (PSk) of the one or more phoneme segments (PS); extracting a portion of the recorded speech, said portion corresponding to a first timeframe ({tilde over (T)}) that comprises the selected phoneme segment; receiving a representation () of a phoneme of interest P*; and applying a machine learning (ML) model on (a) the extracted portion of the recorded speech and (b) on the representation () of the phoneme of interest P*, to generate a modified version of the extracted portion of recorded speech, wherein the phoneme of interest (P*) substitutes the selected phoneme segment (PSk).
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公开(公告)号:US20220323018A1
公开(公告)日:2022-10-13
申请号:US17615919
申请日:2020-06-03
Applicant: RAMBAM MED-TECH LTD.
Inventor: Anat SHROT , Michael ROIMI
Abstract: A method for predicting a medical condition in a patient, the method comprising: receiving, with respect to each of a plurality of subjects, a plurality of clinical parameters, and an outcome indication with respect the said medical condition; applying to said plurality of clinical parameters one or more feature selection algorithms, to select a subset of said plurality of clinical parameters as the most relevant predictors; at a training stage, training a machine learning model on a training set comprising: (i) said relevant predictors with respect to each of said subjects, and (ii) labels associated with said outcome indication in said subject; and at an inference stage, applying said trained machine learning model to a target subset of said relevant predictors with respect to a target patient, to predict said medical condition in said target patient.
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公开(公告)号:US20210338304A1
公开(公告)日:2021-11-04
申请号:US17319157
申请日:2021-05-13
Inventor: Yakov KRASIK , Joshua FELSTEINER , Yakov SLUTSKER , Ziv GIL , Jacob COHEN , Yoav BINENBAUM
Abstract: A system for generating cold plasma is presented, suitable for use in in-vivo treatment of biological tissue. The system comprising: a control unit connectable to an elongated member at a first proximal end of the elongated member. The elongated member comprises a plasma generating unit at a second distal end thereof and gas and electricity transmission channels extending from said first proximal end towards said plasma generating unit. The control unit comprises a gas supply unit configured to provide predetermined flow rate of selected gas composition through said gas transmission channel and a power supply unit configured to generate selected sequence of high-frequency electrical pulses, typically in mega Hertz range, directed through said electricity transmission channel, thereby providing power and gas of said selected composition to the plasma generating unit for generating cold plasma.
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公开(公告)号:US10695462B2
公开(公告)日:2020-06-30
申请号:US15516805
申请日:2015-10-07
Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. , Rambam Med-Tech Ltd.
Inventor: Oded Shoseyov , Danny Porath , Ofra Benny , Yaron Bar-Lavie , Amos Ofer
Abstract: The invention disclosed herein generally provides implantable medical devices and implants that may be removed on-demand from a subject's body at any time after their implanting in the body, without necessitating invasive procedures.
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公开(公告)号:US20190231846A1
公开(公告)日:2019-08-01
申请号:US16222091
申请日:2018-12-17
Inventor: Udi NUSSINOVITCH , Lior GEPSTEIN
CPC classification number: A61K38/164 , A61K35/33 , A61K35/34 , A61K38/168 , A61K48/00 , A61K48/005 , A61K48/0075 , A61N5/062 , A61N2005/0662
Abstract: The present invention relates to methods for attenuating cardiac activity, thereby treating cardiac disease and disorders associated with irregular or increased cardiac activity.
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公开(公告)号:US20180321217A1
公开(公告)日:2018-11-08
申请号:US15972671
申请日:2018-05-07
Inventor: Iyad KHAMAYSI , Eyal ZUSSMAN
IPC: G01N33/487 , G01N33/574 , A61B10/04 , A61B17/34 , G01N11/14
CPC classification number: G01N33/487 , A61B10/04 , A61B17/3403 , A61B2010/045 , A61B2017/3413 , G01N11/14 , G01N33/57438 , G01N2333/705 , G01N2333/928
Abstract: The present invention provides methods for determining malignancy in a cyst by measuring viscosity of cyst fluid while under stain. The invention further provides devices, and computer program products for determining same.
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公开(公告)号:US10105410B2
公开(公告)日:2018-10-23
申请号:US15125340
申请日:2015-03-09
Applicant: RAMBAM MED-TECH LTD.
Inventor: Yona Nadir , Benjamin Brenner
Abstract: The present invention is directed to peptides derived from certain domains of tissue factor pathway inhibitor (TFPI) for use in the treatment of solid tumors and diseases or disorders associated with abnormal clotting.
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30.
公开(公告)号:US20250029722A1
公开(公告)日:2025-01-23
申请号:US18709503
申请日:2022-10-27
Applicant: RAMBAM MED-TECH LTD.
Inventor: Dana BAR ON SHAHAF , Goded SHAHAF
Abstract: A method of determining a type of a brain dysfunction is discloses. The method may include: receiving an electroencephalogram (EEG) signal from an electrode placed on the head; calculating a regularity index for an electric activity of the brain based on EEG signal; detecting a temporal change in the regularity index; receiving a medical related input; and determining the type of brain dysfunction based on the temporal change in the regularity index and the medical related input.
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