公开(公告)号：US20130316985A1

公开(公告)日：2013-11-28

申请号：US13897886

申请日：2013-05-20

Applicant: CORNING INCORPORATED

Inventor： Huayun Deng ,  Ye Fang

IPC: A61K31/655 ,  A61K31/192 ,  A61K31/235 ,  A61K31/381 ,  A61K31/24 ,  A61K31/175 ,  A61K31/06 ,  A61K31/05 ,  A61K31/055

CPC classification number: A61K31/655 ,  A61K31/05 ,  A61K31/055 ,  A61K31/06 ,  A61K31/175 ,  A61K31/192 ,  A61K31/235 ,  A61K31/24 ,  A61K31/381

Abstract: A pharmaceutical composition including at least one compound of the Formulas (I), (II), or (III), or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, as defined herein. Also disclosed is a method of treatment of diseases which are pathophysiologically related to GPR35, the GPR35-hERG signaling complex, or both, as defined herein.

Abstract translation: 包含式（I），（II）或（III）的至少一种化合物或其药学上可接受的盐，溶剂化物，包合物或前药的药物组合物，如本文所定义。 还公开了治疗与本文定义的GPR35，GPR35-hERG信号传导复合物或两者病理生理学相关的疾病的方法。

公开(公告)号：US12063933B1

公开(公告)日：2024-08-20

申请号：US18224348

申请日：2023-07-20

Applicant: CORNING INCORPORATED

Inventor： Theresa Chang ,  Johnathan David Jr. Culpepper ,  Huayun Deng ,  Shu Yuan

IPC: A01N59/20 ,  A01N25/08 ,  A01N25/22

CPC classification number: A01N59/20 ,  A01N25/08 ,  A01N25/22

Abstract: Biocidal compositions including a carrier, a copper(I) salt, and a copper-assisting additive different from the carrier are provided, which in some aspects have improved antimicrobial efficacy and/or total color difference. Also provided are biocidal compositions or UV curable films thereof that exhibit high transmittance that is similar to the transmittance of an otherwise identical composition or film thereof without either the copper(I) salt or the copper-assisting additive. Also provided are biocidal additive formulations in which a copper(I) salt has a molarity of at least 20 mM.

公开(公告)号：US12052911B2

公开(公告)日：2024-07-30

申请号：US17291406

申请日：2019-10-22

Applicant: Corning Incorporated

Inventor： Huayun Deng ,  Mingqian He ,  Xin Li ,  Yang Li ,  Weijun Niu ,  Arthur Lawrence Wallace ,  Hongxiang Wang

IPC: H10K85/10 ,  C08G61/12 ,  H10K10/46

CPC classification number: H10K85/113 ,  C08G61/126 ,  H10K85/151 ,  C08G2261/124 ,  C08G2261/1412 ,  C08G2261/18 ,  C08G2261/228 ,  C08G2261/3223 ,  C08G2261/3241 ,  C08G2261/3243 ,  C08G2261/92 ,  H10K10/466 ,  H10K10/484

Abstract: A cross-bred organic semiconductor (OSC) polymer, includes a diketopyrrolopyrrole (DPP)-fused thiophene polymeric material, such that: the DPP-fused thiophene polymeric material comprises a first linear alkyl-substituted DPP portion and a second branched alkyl-substituted DPP portion, the cross-bred OSC polymer comprises a repeat unit having both the first linear alkyl-substituted DPP portion and the second branched alkyl-substituted DPP portion, and the fused thiophene is beta-substituted.

公开(公告)号：US20240026296A1

公开(公告)日：2024-01-25

申请号：US18376260

申请日：2023-10-03

Applicant: CORNING INCORPORATED

Inventor： Huayun Deng ,  Qiang Fu ,  John Christopher Mauro

IPC: C12N5/077 ,  C03C3/097 ,  C03C3/11 ,  C03C3/118 ,  C03C10/00 ,  A61K35/32 ,  C03C4/00

CPC classification number: C12N5/0654 ,  C03C3/097 ,  C03C3/111 ,  C03C3/118 ,  C03C10/0027 ,  A61K35/32 ,  C03C4/0014 ,  C03C10/0009 ,  C03C2205/06 ,  C03C2204/00 ,  C12N2533/12

Abstract: A glass-ceramic composition as defined herein. The glass-ceramic composition includes a first crystalline phase comprising lithium disilicate. The glass-ceramic composition can include up to 10 wt % CaO, up to 5 wt % Na2O, up to 10 wt % B2O3, and greater than 0.5 wt % ZrO2. The glass-ceramic composition can also include from 50 to 75 wt % SiO2, from 1 to 5 wt % Al2O3, from 1 to 8 wt % P2O5, and from 5 to 20 wt % Li2O. In aspects, the glass-ceramic composition can include a second crystalline phase including wollastonite, apatite, cristobalite, β-quartz, lithiophosphate, or a combination thereof. Also disclosed are methods of making and using the disclosed compositions.

公开(公告)号：US11814649B2

公开(公告)日：2023-11-14

申请号：US16163013

申请日：2018-10-17

Applicant: Corning Incorporated

Inventor： Huayun Deng ,  Qiang Fu ,  John Christopher Mauro

IPC: C03C10/00 ,  C03C3/118 ,  C03C3/11 ,  C03C3/097 ,  A61K35/32 ,  C03C4/00 ,  C12N5/077

CPC classification number: C12N5/0654 ,  A61K35/32 ,  C03C3/097 ,  C03C3/111 ,  C03C3/118 ,  C03C4/0014 ,  C03C10/0009 ,  C03C10/0027 ,  C03C2204/00 ,  C03C2205/06 ,  C12N2533/12

Abstract: A bioactive glass-ceramic composition as defined herein. Also disclosed are methods of making and using the disclosed compositions.

公开(公告)号：US11446410B2

公开(公告)日：2022-09-20

申请号：US17076410

申请日：2020-10-21

Applicant: CORNING INCORPORATED

Inventor： Huayun Deng ,  Qiang Fu ,  John Christopher Mauro

IPC: C03C10/04 ,  C03C10/12 ,  A61L27/10 ,  A61L24/02 ,  C03C21/00 ,  C03C10/00 ,  C03C10/16 ,  C03C4/00 ,  C03C4/18 ,  A61L24/00 ,  A61L27/12 ,  A61L27/04 ,  A61L27/02 ,  C03C3/097 ,  C03C3/118 ,  C03C3/112 ,  C03B25/02

Abstract: A chemically strengthened bioactive glass-ceramic composition as defined herein. Also disclosed are methods of making and using the disclosed compositions.

公开(公告)号：US20220267198A1

公开(公告)日：2022-08-25

申请号：US17631527

申请日：2020-08-07

Applicant: CORNING INCORPORATED ,  DuPont Electronics, Inc. ,  Rohm and Haas Electronic Materials LLC

Inventor： Lujia Bu ,  Huayun Deng ,  Suraj S Deshpande ,  Ross Stefan Johnson ,  Ying Zhang

IPC: C03C17/32

Abstract: Glass articles having a thin glass layer and atop optically transparent polymeric hard-coat layer disposed on atop surface of the thin glass layer. The top optically transparent polymeric hard-coat layer may have a thickness in a range of 0.1 microns to 200 microns and a pencil hardness of 6H or more, when the pencil hardness is measured with the optically transparent polymeric hard-coat layer disposed on the top surface of the glass layer. The glass articles avoid ejection of glass shard particles from the glass article upon bending to a failure during a static two-point bend test.

公开(公告)号：US20220155683A1

公开(公告)日：2022-05-19

申请号：US17440387

申请日：2020-03-05

Applicant: Corning Incorporated

Inventor： Huayun Deng ,  Mingqian He ,  Yang Li ,  Weijun Niu ,  Hongxiang Wang

IPC: G03F7/038 ,  G03F7/11 ,  G03F7/38 ,  G03F7/40 ,  G03F7/32 ,  G03F7/004

Abstract: A polymer blend, including at least one organic semiconductor (OSC) polymer, such that: the at least one OSC polymer is a diketopyrrolopyrrole-fused thiophene polymeric material, the fused thiophene is beta-substituted, the at least one OSC polymer has a first portion and a second portion, and at least one of the first portion or the second portion includes at least one UV-curable side chain.

公开(公告)号：US10647962B2

公开(公告)日：2020-05-12

申请号：US15602819

申请日：2017-05-23

Applicant: Corning Incorporated

Inventor： Huayun Deng ,  Ye Fang ,  Qiang Fu ,  John Christopher Mauro

IPC: C12N5/077 ,  C03C3/19 ,  C03C4/00 ,  A61L27/54 ,  A61L27/10 ,  A61K35/32

Abstract: An aluminoborate glass composition, including B2O3, Al2O3, P2O5, Na2O, and CaO, as defined herein. Also disclosed are bioactive compositions including the disclosed aluminoborate glass composition, a suitable fluid, and at least one live cell. Also disclosed is method of limiting the amount of boron released into an aqueous solution from a disclosed aluminoborate-containing glass composition as defined herein. Also disclosed is a method of proliferating cells on a bioactive substrate as defined herein.

公开(公告)号：US20170342383A1

公开(公告)日：2017-11-30

申请号：US15603006

申请日：2017-05-23

Applicant: Corning Incorporated

Inventor： Huayun Deng ,  Qiang Fu ,  John Christopher Mauro

IPC: C12N5/077 ,  C03C4/00 ,  A61K35/32 ,  C03C10/00

CPC classification number: C12N5/0654 ,  A61K35/32 ,  C03C3/097 ,  C03C3/111 ,  C03C3/118 ,  C03C4/0014 ,  C03C10/0009 ,  C03C10/0027 ,  C03C2204/00 ,  C03C2205/06 ,  C12N2533/12

Abstract: A bioactive glass-ceramic composition as defined herein. Also disclosed are methods of making and using the disclosed compositions.