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公开(公告)号：US09161798B2
公开(公告)日：2015-10-20
申请号：US12728127
申请日：2010-03-19
申请人： Csaba Truckai , Andrew Kohm , John Shadduck
发明人： Csaba Truckai , Andrew Kohm , John Shadduck
CPC分类号： A61B17/8836 , A61B17/8822 , A61B90/98 , A61B2017/00084
摘要： Systems and methods for treating vertebral compression fractures are provided. A kit can include at least one body containing a bone cement precursor to be mixed with at least one other bone cement precursor to form a bone cement. The body or a package containing the body can include at least one sensor. In some embodiments the sensor can be a temperature sensor. In some methods, data from the sensor can be used to determine certain parameters related to a treatment interval involving the bone cement.
摘要翻译： 提供了治疗椎体压缩性骨折的系统和方法。 试剂盒可以包括至少一个含有待与至少一种其他骨水泥前体混合以形成骨粘固剂的骨水泥前体的主体。 身体或包含身体的包装可以包括至少一个传感器。 在一些实施例中，传感器可以是温度传感器。 在一些方法中，可以使用来自传感器的数据来确定与涉及骨水泥的治疗间隔相关的某些参数。
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公开(公告)号：US20110004208A1
公开(公告)日：2011-01-06
申请号：US12605742
申请日：2009-10-26
申请人： Csaba Truckai , John Shadduck , James Baker
发明人： Csaba Truckai , John Shadduck , James Baker
IPC分类号： A61B18/14
CPC分类号： A61B18/1442 , A61B17/32 , A61B2017/2945 , A61B2018/00619 , A61B2018/00755 , A61B2018/00791 , A61B2018/00875 , A61B2018/1432 , A61B2018/1495
摘要： Various embodiments provide an electrosurgical instrument with a disposable electrosurgical cartridge. In one embodiment, the cartridge has first and second energy-delivery surfaces that carry first and second opposing polarity conductors coupled to a voltage source, together with first and second temperature-responsive variable impedance bodies exposed partly in the respective-delivery surfaces. The cartridge further carries a slidable blade member. The temperature-responsive variable impedance bodies are coupled to the voltage source by series and parallel circuitry. In use, the variable impedance bodies are adapted to modulate current flow and ohmic heating in engaged tissue by providing controlled current paths in the tissue and through the variable impedance bodies as the temperature-responsive bodies sense the temperature of adjacent engaged tissue. The engagement surfaces are capable of highly localized modulation of Rf energy application to engaged tissue to provide high and low temperatures, voltage and current in the tissue to create high strength welds.
摘要翻译： 各种实施例提供具有一次性电外科手术盒的电外科器械。 在一个实施例中，盒具有第一和第二能量传递表面，其承载耦合到电压源的第一和第二相对极性导体以及部分地暴露在相应输送表面中的第一和第二温度响应可变阻抗体。 该盒还带有可滑动的刀片部件。 温度响应可变阻抗体通过串联和并联电路耦合到电压源。 在使用中，可变阻抗体适于通过在温度响应体感测相邻接合组织的温度时通过在组织中和通过可变阻抗体中提供受控的电流路径来调制接合组织中的电流和欧姆加热。 接合表面能够对接合组织进行Rf能量的高度局部调节，以在组织中提供高和低温度，电压和电流以产生高强度焊缝。
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公开(公告)号：US20090292290A1
公开(公告)日：2009-11-26
申请号：US12427531
申请日：2009-04-21
申请人： Csaba Truckai , Andrew Kohm , John Shadduck
发明人： Csaba Truckai , Andrew Kohm , John Shadduck
IPC分类号： A61B17/58
CPC分类号： A61B17/8805 , A61B17/7095 , A61B17/8822 , A61B17/8827
摘要： Systems, bone cements and methods for treating vertebral compression fractures can utilize a bone cement comprising of a mixable liquid monomer component and a non-liquid component including polymer particles, wherein the non-liquid component is configured for controlled exposure to the liquid monomer over a setting interval of the bone cement. In a method of use, liquid and non-liquid components are mixed, and the bone cement is injected into bone wherein a lengthened setting interval is provided in which the mixture is configured for a flowability that prevents unwanted extravasation.
摘要翻译： 用于治疗脊椎压缩性骨折的系统，骨水泥和方法可以利用包含可混合液体单体组分和包括聚合物颗粒在内的非液体组分的骨粘固剂，其中非液体组分构造成用于通过液体单体控制暴露于液体单体 骨水泥的设定间隔。 在使用方法中，将液体和非液体组分混合，并将骨粘固剂注入到骨中，其中提供了延长的凝固间隔，其中混合物配置为防止不想要的外渗的流动性。
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公开(公告)号：US20080086196A1
公开(公告)日：2008-04-10
申请号：US11953809
申请日：2007-12-10
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61F2/06
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12118 , A61B17/12145 , A61B17/12172 , A61B17/12181 , A61B2017/12068 , A61F2/07 , A61F2/848 , A61F2220/0016
摘要： A system for treating a wide-neck aneurysm comprising a mesh-like sleeve fabricated from a class of polymer filaments that carry conductive particles therein to provide the filaments with a specified resistivity. The releasable mesh-like sleeve is introduced to the site of a targeted vascular malformation by the working end of a catheter that carries an electrode arrangement at its distal terminus. The system further provides an electrical source and controller (i) that modulates power delivery to the polymer matrix which can then fuse the sleeve to the wall of a blood vessel to span across the vascular malformation.
摘要翻译： 一种用于治疗宽颈动脉瘤的系统，包括由一类聚合物长丝制成的网状套筒，所述聚合物细丝在其中携带导电颗粒以提供具有指定电阻率的细丝。 可释放的网状套筒通过导管的工作端引导到目标血管畸形部位，该导管在其远端具有电极装置。 该系统还提供一种电源和控制器（i），其调节向聚合物基质的功率传递，然后可将该套管熔合到血管的壁以横跨血管畸形。
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公开(公告)号：US20060122625A1
公开(公告)日：2006-06-08
申请号：US11209035
申请日：2005-08-22
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61F2/34
CPC分类号： A61B17/8805 , A61B17/70 , A61B17/8822 , A61B17/8827 , A61B17/8836 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61B2017/564 , A61F2/44
摘要： The present invention relates in certain embodiments to medical devices for treating vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the flow of bone cement into the interior of a vertebra and the application of forces causes by the cement flow. An exemplary system utilizes Rf energy in combination a conductive bone cement for selectively polymerizing the inflow plume to increase the viscosity of the cement. In one aspect of the invention, the system utilizes a controller to control bone cement flow parameters to either allow or disallow cement interdigitation into cancellous bone. A method of the invention includes pulsing the flows of bone cement wherein high acceleration of the flow pulses can apply expansion forces across the surface of the cement plume to reduce a vertebral fracture.
摘要翻译： 本发明在某些实施例中涉及用于治疗脊椎压缩性骨折的医疗装置。 更具体地，本发明的实施例涉及通过控制骨水泥进入椎骨内部并且由水泥流引起的力的施加来可控地恢复椎体高度的仪器和方法。 示例性系统利用结合导电骨水泥的Rf能量来选择性聚合流入羽流以增加水泥的粘度。 在本发明的一个方面，该系统利用控制器来控制骨水泥流动参数以允许或不允许水泥交叉指向松质骨。 本发明的方法包括脉动骨粘固剂的流动，其中流动脉冲的高加速度可以施加穿过水泥羽流表面的膨胀力，以减少椎骨骨折。
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公开(公告)号：US20060106459A1
公开(公告)日：2006-05-18
申请号：US11215730
申请日：2005-08-30
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61F2/44
CPC分类号： A61B17/8836 , A61B17/7095 , A61B17/7098
摘要： A system for treating an abnormal vertebral body such as a compression fracture. In an exemplary embodiment, the system includes a biocompatible flow-through implant structure configured with a three-dimensional interior web that defines flow openings therein for cooperating with a two-part hardenable bone cement. The flow-through structure is capable of compacted and extended shapes and in one embodiment provides a gradient in flow openings for controlling flow parameters of a bone cement injected under high pressure into the interior thereof. The flow-through implant structure is configured for transducing cement injection forces into a selected direction for moving apart cortical endplates of a vertebra to reduce a fracture. In one embodiment, the flow-through implant structure is coupled to an Rf source for applying Rf energy to a two-part bone cement to accelerate curing of the cement to thereby allow on-demand alterations of cement viscosity. The Rf system allows for control of bone cement polymerization globally or regionally to prevent cement extravasion and to direct forces applied to a vertebra to reduce a fracture.
摘要翻译： 用于治疗异常椎体的系统，例如压缩性骨折。 在一个示例性实施例中，该系统包括生物相容性流通植入结构，该植入结构被构造成具有限定其中的流动开口的三维内部腹板，用于与两部分可硬化骨粘固剂配合。 流通结构能够压实和延伸形状，并且在一个实施例中提供流动开口中的梯度，用于控制在高压下注入其内部的骨粘固剂的流动参数。 流通植入结构被配置为将水泥注射力转换到选定的方向以移动分开的椎骨的皮层终板以减少骨折。 在一个实施例中，流过植入结构耦合到Rf源，以将Rf能量施加到两部分骨水泥以加速水泥的固化，从而允许水泥粘度的按需改变。 Rf系统允许全局或区域地控制骨水泥聚合，以防止水泥外渗，并引导施加到椎骨上的力以减少骨折。
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公开(公告)号：US20050267464A1
公开(公告)日：2005-12-01
申请号：US10973818
申请日：2004-10-25
申请人： Csaba Truckai , John Shadduck , Bruno Strul , James Baker
发明人： Csaba Truckai , John Shadduck , Bruno Strul , James Baker
IPC分类号： A61B18/14
CPC分类号： A61B18/1442 , A61B2018/00619
摘要： An embodiment of a method of the invention provides a method for welding tissue comprising providing a tissue welding device having first and second tissue engaging surfaces with at least one surface including an electrode surface that defines a plurality of surface portions having different resistances to electrical current flow therethrough. A target tissue volume is engaged with the tissue engaging surfaces. Rf energy is delivered to the target volume to create a substantially even temperature distribution across at least a portion of the target tissue volume to substantially uniformly weld at least a portion of the target tissue volume.
摘要翻译： 本发明的方法的一个实施例提供了一种焊接组织的方法，包括提供具有第一和第二组织接合表面的组织焊接装置，其中至少一个表面包括限定对电流流动具有不同电阻的多个表面部分的电极表面 通过。 目标组织体积与组织接合表面接合。 将Rf能量传递到目标体积以在目标组织体积的至少一部分上产生基本均匀的温度分布，以基本均匀地焊接目标组织体积的至少一部分。
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公开(公告)号：US20050192568A1
公开(公告)日：2005-09-01
申请号：US11118881
申请日：2005-04-29
申请人： Csaba Truckai , James Baker , Bruno Strul , John Shadduck
发明人： Csaba Truckai , James Baker , Bruno Strul , John Shadduck
IPC分类号： A61B18/14
CPC分类号： A61B18/1442 , A61B2018/00077 , A61B2018/00083 , A61B2018/00148 , A61B2018/0063 , A61B2018/00809
摘要： A working end of a surgical instrument that carries first and second jaws for delivering energy to tissue. In a preferred embodiment, at least one jaw of the working end defines a tissue-engagement plane that contacts the targeted tissue. The cross-section of the engagement plane reveals that it defines a surface conductive portion that overlies a variably resistive matrix of a temperature-sensitive resistive material or a pressure-sensitive resistive material. An interior of the jaw carries a conductive material or electrode that is coupled to an Rf source and controller. In an exemplary embodiment, the variably resistive matrix can comprise a positive temperature coefficient (PTC) material, such as a ceramic, that is engineered to exhibit a dramatically increasing resistance (i.e., several orders of magnitude) above a specific temperature of the material.
摘要翻译： 手术器械的工作端，其携带用于将能量递送至组织的第一和第二钳口。 在优选实施例中，工作端的至少一个钳口限定了接触目标组织的组织接合平面。 接合平面的横截面显示它限定了覆盖在温度敏感电阻材料或压敏电阻材料的可变电阻矩阵上的表面导电部分。 钳口的内部承载耦合到Rf源和控制器的导电材料或电极。 在示例性实施例中，可变电阻矩阵可以包括正温度系数（PTC）材料，例如陶瓷，其被工程化以显示高于材料的特定温度的显着增加的电阻（即几个数量级）。
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公开(公告)号：US08523871B2
公开(公告)日：2013-09-03
申请号：US12062337
申请日：2008-04-03
申请人： Csaba Truckai , Robert Luzzi , John H. Shadduck , Robert D. Poser
发明人： Csaba Truckai , Robert Luzzi , John H. Shadduck , Robert D. Poser
CPC分类号： A61B17/8836 , A61B17/8822 , A61B2017/00022
摘要： Systems and methods for delivering bone cement into a bone can include a handle body defining a flow path, a thermal emitter in the handle body to apply energy to bone cement passing through the flow path, a source of bone cement and an injection cannula. The cannula can be in communication with the flow path such that inserting the cannula into a bone can allow a flow of bone cement therethrough to an opening at a distal end of the cannula. Other systems and methods for delivering bone cement into a bone can include an injector body with a handle portion, and a cannula, a bone cement container, a low pressure drive mechanism configured to effect a flow of bone cement from said container to the injector body and a high pressure drive mechanism configured to effect a flow of bone cement through the injector body into the bone.
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公开(公告)号：US20090275995A1
公开(公告)日：2009-11-05
申请号：US12502163
申请日：2009-07-13
CPC分类号： A61B17/8836 , A61B17/864 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61F2/44
摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. A method of treating bone includes injecting a volume of fill material into a bone and selectively modifying a viscosity of the bone filler to control the direction of flow of the fill material within the bone. A system for treating bone using this method includes an introducer for delivering fill material into the bone and an energy source selectively coupleable to the fill material to alter the viscosity of the fill material via an energy emitter in the introducer.
摘要翻译： 本发明在某些实施例中涉及用于治疗诸如椎体压缩性骨折的骨整形术程序的医疗装置。 更具体地，本发明的实施例涉及通过控制引入松质骨的填充材料的几何形状来可控地恢复椎体高度的仪器和方法。 治疗骨的方法包括将一定体积的填充材料注入骨骼中，并选择性地改变骨填充物的粘度以控制骨中填充材料的流动方向。 使用该方法治疗骨的系统包括用于将填充材料输送到骨中的导引器和能够选择性地与填充材料相连的能量源，以经由引入器中的能量发射器改变填充材料的粘度。
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