公开(公告)号：US5410059A

公开(公告)日：1995-04-25

申请号：US166977

申请日：1993-12-14

Applicant: David Fraser ,  Shaik M. Zakeeruddin ,  Michael Graetzel

Inventor： David Fraser ,  Shaik M. Zakeeruddin ,  Michael Graetzel

IPC: C07D213/22 ,  C07D213/38 ,  C07D213/68 ,  C07D213/73 ,  C07D213/74 ,  C07F15/00 ,  C07F15/02 ,  C12Q1/00 ,  C12Q1/26 ,  C12Q1/54 ,  G01N27/327 ,  H01L51/00 ,  H01L51/30

CPC classification number: C07D213/22 ,  C07F15/0026 ,  C07F15/0053 ,  C07F15/025 ,  C12Q1/004 ,  H01L51/0086

Abstract: Complexes of the general formula I ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3, which may be the same or different, each represent a straight or branched alkyl radical having 1 to 5 carbon atoms or together with the adjacent nitrogen atom a heterocyclic radical having 5 to 7 carbon atoms; "alk" represents a straight or branched alkylene radical having 1 to 5 carbon atoms; R.sub.4 to R.sub.8, which may be the same or different, represent hydrogen, or a hydroxy, alkoxy, aryloxy or primary secondary or tertiary amino group, or the group -alk-N.sup.+ (R.sub.1 R.sub.2 R.sub.3) wherein "alk", R.sub.1, R.sub.2 and R.sub.3 have the meanings given above; M represents a transition metal such as Fe, Ru or Os; X represents an anion and n is an integer corresponding to the number of positive charges of the complex.

Abstract translation: 通式I（I）的络合物其中R 1，R 2和R 3可以相同或不同，表示具有1至5个碳原子的直链或支链烷基或与相邻的氮原子一起形成杂环基 具有5至7个碳原子的基团; “alk”表示具有1至5个碳原子的直链或支链亚烷基; R 4至R 8可以相同或不同，表示氢或羟基，烷氧基，芳氧基或一级仲或叔氨基或-alk-N +（R 1 R 2 R 3），其中“alk”，R 1，R 2和R 3 具有上述含义; M表示Fe，Ru或Os等过渡金属; X表示阴离子，n是与络合物的正电荷数相对应的整数。

公开(公告)号：US5378628A

公开(公告)日：1995-01-03

申请号：US938219

申请日：1992-10-19

Applicant: Michael Gratzel ,  David Fraser ,  Shaik M. Zakeeruddin ,  Jean-Paul Randin ,  Erik J. Frenkel

Inventor： Michael Gratzel ,  David Fraser ,  Shaik M. Zakeeruddin ,  Jean-Paul Randin ,  Erik J. Frenkel

IPC: G01N27/28 ,  C12Q1/00 ,  G01N27/30 ,  G01N27/327 ,  G01N27/416 ,  G01N31/00 ,  G01N27/26

CPC classification number: C12Q1/006 ,  C12Q1/004 ,  Y10S435/817

Abstract: A sensor for measuring the amount of a component in solution is disclosed. The sensor has a measuring electrode with at least one current collector, electrically connected to one of the electrical contacts and coated with a mixture comprising at least one oxidation-reduction enzyme specific to said component and at least one mediator transferring the electrons between said enzyme and said current collector wherein the mediator is a transition metal complex with at least one bipyridine, terpyridine or phenanthroline ligand substituted by at least one electron donor group. This sensor is particularly useful in the detection of glucose.

Abstract translation: PCT No.PCT / CH92 / 00034 Sec。 371日期：1992年10月19日 102（e）日期1992年10月19日PCT提交1992年2月19日PCT公布。 WO92 / 14836 PCT公开号 公开了一种用于测量溶液中组分的量的传感器。 传感器具有至少一个集电器的测量电极，其电连接到一个电触头并涂覆有包含至少一种对所述组分特异的氧化还原酶的混合物和至少一个在所述酶和所述酶之间转移电子的介体 所述集流体，其中介体是与至少一个被至少一个电子给体基团取代的联吡啶，三联吡啶或菲咯啉配体的过渡金属络合物。 该传感器在葡萄糖检测中特别有用。