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公开(公告)号：US08926553B2
公开(公告)日：2015-01-06
申请号：US10433642
申请日：2001-12-21
CPC分类号： A61M5/14244 , A61M5/14566 , A61M5/20 , A61M5/31525 , A61M5/31546 , A61M2005/31588 , A61M2205/215 , A61M2205/50 , A61M2205/6018 , A61M2205/8206 , G06F19/00 , Y10S128/01
摘要： An injection device having a drive mechanism to expel selectively a dose of medicament from a medicament cartridge through a needle unit is disclosed. The injection device further comprises an electronic control unit to control the drive mechanism, and a dispense button to generate a dispense button signal to the electronic control unit indicative of the dose to be expelled in which an arm button causes a first arm button signal to be sent to the electronic control unit to permit the dose to be expelled.
摘要翻译： 公开了一种具有驱动机构的注射装置，其通过针单元从药剂盒中选择性地排出剂量的药物。 注射装置还包括用于控制驱动机构的电子控制单元和分配按钮，用于向电子控制单元生成指示要排出的剂量的分配按钮信号，其中手臂按钮使第一臂按钮信号为 发送到电子控制单元以允许剂量被排出。
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公开(公告)号：US08888750B2
公开(公告)日：2014-11-18
申请号：US13025852
申请日：2011-02-11
CPC分类号： A61M5/31528 , A61M5/24 , A61M5/2422 , A61M5/31501 , A61M5/31511 , A61M5/31526 , A61M5/31533 , A61M5/31541 , A61M5/3155 , A61M5/31551 , A61M5/3156 , A61M5/31583 , A61M5/31585 , A61M5/31593 , A61M2205/581 , A61M2205/582
摘要： A pen-type injector is improved so that a user may select a delivery dose of a medicinal product from a multidose cartridge. The injector includes a housing, the cartridge containing the medicinal product retained within the housing, a piston rod, a dose selecting member to select the dose of the medicinal product to be expelled, and a drive member to expel the selected dose of the medicinal product. The housing is formed unitary so that the dose selecting member and the drive member are moveably retained within the housing. The injector may include a ratchet associated with an insert to ensure the piston rod only rotates in a single direction through the insert, a button located on the drive sleeve, and a clutch which upon depression of the button prevents rotation between the dose dial sleeve and the drive sleeve.
摘要翻译： 笔式注射器被改进，使得使用者可以从多剂量药筒选择药物的递送剂量。 注射器包括壳体，容纳保存在壳体内的药用产品的药筒，活塞杆，选择要排出的药物的剂量的剂量选择构件以及驱逐所选剂量的药物的驱动构件 。 壳体形成为一体，使得剂量选择构件和驱动构件可移动地保持在壳体内。 注射器可以包括与插入件相关联的棘轮，以确保活塞杆仅沿着单个方向通过插入件旋转，位于驱动套筒上的按钮和在按下按钮时阻止剂量拨号套筒和 驱动套筒。
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公开(公告)号：US08617127B2
公开(公告)日：2013-12-31
申请号：US10315165
申请日：2002-12-10
IPC分类号： A61M5/00
CPC分类号： A61M5/24 , A61M5/14566 , A61M5/16831 , A61M5/31525 , A61M5/31546 , A61M5/3157 , A61M5/31591 , A61M2005/31588 , A61M2205/52 , A61M2205/581
摘要： A medicament injection device in which the time elapsed is calculated from the end of a predetermined period during which medicament is permitted to disperse subsequent to completion of an injection stroke. The medicament injection device is particularly suitable for use by those with diabetes in which once a desired dosage of medicament has been selected and expelled from the medicament cartridge into the body of the patient, the injected medicament is allowed to disperse locally from the injection site within the patient's body before the needle arrangement is removed from the patient's body.
摘要翻译： 一种药物注射装置，其中从在注射冲程完成之后允许药物分散的预定时期的结束计算经过的时间。 药物注射装置特别适用于糖尿病患者，其中一旦已经选择了期望剂量的药物并从药剂盒中排出到患者体内，则注射的药物被允许从注射部位局部分散 在针排列之前的患者身体被从病人的身体移除。
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公开(公告)号：US08574198B2
公开(公告)日：2013-11-05
申请号：US13280903
申请日：2011-10-25
CPC分类号： A61M5/31528 , A61M5/24 , A61M5/2422 , A61M5/31501 , A61M5/31511 , A61M5/31526 , A61M5/31533 , A61M5/31541 , A61M5/3155 , A61M5/31551 , A61M5/3156 , A61M5/31583 , A61M5/31585 , A61M5/31593 , A61M2205/581 , A61M2205/582
摘要： The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.
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公开(公告)号：US20120215176A1
公开(公告)日：2012-08-23
申请号：US13280903
申请日：2011-10-25
IPC分类号： A61M5/315
CPC分类号： A61M5/31528 , A61M5/24 , A61M5/2422 , A61M5/31501 , A61M5/31511 , A61M5/31526 , A61M5/31533 , A61M5/31541 , A61M5/3155 , A61M5/31551 , A61M5/3156 , A61M5/31583 , A61M5/31585 , A61M5/31593 , A61M2205/581 , A61M2205/582
摘要： The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.
摘要翻译： 本公开涉及可以与药物递送装置一起使用的剂量设定机构。 剂量设定机构可以包括具有沿着内体的外圆柱形表面的螺旋形螺纹的内体和用于沿轴向驱动活塞杆的驱动套筒，驱动套筒位于内体的至少一部分内 。 剂量设定机构还可以包括可旋转地与内体的螺旋螺纹接合的剂量拨片套筒和连接到剂量拨盘套筒并且可释放地连接到驱动套筒的拨号手柄。 此外，当设定剂量时，旋转手柄旋转，使得剂量拨盘套筒和驱动套筒相对于内部主体旋转。
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公开(公告)号：US08070727B2
公开(公告)日：2011-12-06
申请号：US12453626
申请日：2009-05-15
CPC分类号： A61M5/31528 , A61M5/24 , A61M5/2422 , A61M5/31501 , A61M5/31511 , A61M5/31526 , A61M5/31533 , A61M5/31541 , A61M5/3155 , A61M5/31551 , A61M5/3156 , A61M5/31583 , A61M5/31585 , A61M5/31593 , A61M2205/581 , A61M2205/582
摘要： The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.
摘要翻译： 本公开涉及可以与药物递送装置一起使用的剂量设定机构。 剂量设定机构可以包括具有沿着内体的外圆柱形表面的螺旋形螺纹的内体和用于沿轴向驱动活塞杆的驱动套筒，驱动套筒位于内体的至少一部分内 。 剂量设定机构还可以包括可旋转地与内体的螺旋螺纹接合的剂量拨片套筒和连接到剂量拨盘套筒并且可释放地连接到驱动套筒的拨号手柄。 此外，当设定剂量时，旋转手柄旋转，使得剂量拨盘套筒和驱动套筒相对于内部主体旋转。
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公开(公告)号：US07794430B2
公开(公告)日：2010-09-14
申请号：US10471721
申请日：2002-03-26
CPC分类号： A61M5/3158 , A61M5/24 , A61M5/31541 , A61M5/31553 , A61M5/31563 , A61M5/31593 , A61M2005/2414
摘要： Injection devices are known for the self administration of medicament by patients in which the medicaments is typically contained within a cartridge located within the injection device. It is a problem that injection devices should be small enough to fit into a jacket pocket or a hand bag without difficulty. Also, the injection device must be of a size that enables a piston or similar used to drive a cartridge bung within the cartridge to be moved both to a maximum dispense position within the cartridge and to be fully withdrawn from the cartridge to allow for replacement of the cartridge. A drive mechanism for an injection device is disclosed in which a piston (48) is successively moved along the first axis to drive a bung (20) into a medicament cartridge (18), a displacement mechanism comprising a dose setting spindle (30) is disposed along a second axis, the second axis being parallel to the first axis, transmission means connected between the dose setting spindle (30) and the piston (20), and displacement means to displace the dose setting spindle (30) with respect to the medicament cartridge (18), a movement of the displacement means in a first direction causing movement of the dose setting spindle (30) and the piston (20) in the first direction.
摘要翻译： 注射装置是已知的，其中药物通常包含在位于注射装置内的药筒内的患者自身给药。 这是一个注射装置应该足够小以难以装入夹克口袋或手提袋的问题。 而且，注射装置必须具有这样的尺寸，使得活塞或类似物用于驱动药筒内的弹药筒被移动到药筒内的最大分配位置并且完全从药筒中取出，以允许更换 墨盒。 公开了一种用于注射装置的驱动机构，其中活塞（48）沿着第一轴线连续移动以将栓（20）驱动到药剂盒（18）中，包括剂量设定主轴（30）的移位机构是 沿着第二轴线布置，第二轴线平行于第一轴线，连接在剂量设定主轴（30）和活塞（20）之间的传动装置，以及使剂量设定主轴（30）相对于所述活塞 药剂盒（18），位移装置在第一方向上的移动，引起剂量设定主轴（30）和活塞（20）在第一方向上的移动。
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公开(公告)号：US07699815B2
公开(公告)日：2010-04-20
申请号：US10433782
申请日：2001-12-21
CPC分类号： A61M5/14244 , A61M5/14566 , A61M5/20 , A61M5/31525 , A61M5/31546 , A61M2005/31588 , A61M2205/215 , A61M2205/50 , A61M2205/6018 , A61M2205/8206 , G06F19/00 , Y10S128/01
摘要： A drive mechanism for an injection device is disclosed in which piston means are selectively driven to expel medicament from within a medicament cartridge. The drive mechanism comprises a drive means associated with a first ratchet member, a second ratchet member associated with the piston means, a housing, the first ratchet member and the second ratchet member being disposed within the housing. The second ratchet member being biased by biasing means toward the first ratchet member. The drive means is actuable reciprocally to drive the first ratchet member in a first angular direction such that the first ratchet member drives the second ratchet member along its longitudinal axis against the biasing means along at least a part of its movement and subsequently drives the first ratchet member and the second ratchet member together in a second angular direction thereby to drive the piston means.
摘要翻译： 公开了一种用于注射装置的驱动机构，其中选择性地驱动活塞装置以从药剂盒内排出药物。 驱动机构包括与第一棘轮构件相关联的驱动装置，与活塞装置相关联的第二棘轮构件，壳体，第一棘轮构件和第二棘轮构件设置在壳体内。 第二棘轮构件通过偏压装置朝向第一棘轮构件偏置。 驱动装置可往复驱动以沿第一角度方向驱动第一棘轮构件，使得第一棘轮构件沿其纵向轴线沿其纵向轴线沿其运动的至少一部分驱动第二棘轮构件，并随后驱动第一棘轮 构件和第二棘轮构件一起在第二角度方向上，从而驱动活塞装置。
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公开(公告)号：US07553299B2
公开(公告)日：2009-06-30
申请号：US10790024
申请日：2004-03-02
IPC分类号： A61M5/00
CPC分类号： A61M5/31528 , A61M5/24 , A61M5/2422 , A61M5/31501 , A61M5/31511 , A61M5/31526 , A61M5/31533 , A61M5/31541 , A61M5/3155 , A61M5/31551 , A61M5/3156 , A61M5/31583 , A61M5/31585 , A61M5/31593 , A61M2205/581 , A61M2205/582
摘要： A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a piston rod, and a unidirectional coupling between the housing and the piston rod. The drive mechanism may also include a dose dial sleeve and a drive sleeve, with a clutch mean located therebetween to prevent relative rotation between the dial sleeve and the drive sleeve when in a coupled state and to permit relative rotation between the dial sleeve and the drive sleeve when in a de-coupled state.
摘要翻译： 公开了一种适用于药物输送装置的驱动机构。 驱动机构可以与注射器型药物递送装置一起使用，例如允许用户设定递送剂量的那些。 驱动机构可以包括壳体，活塞杆以及壳体和活塞杆之间的单向联接。 驱动机构还可以包括剂量拨号套筒和驱动套筒，其中离合器装置位于它们之间以防止当处于联接状态时拨盘套筒和驱动套筒之间的相对旋转，并允许拨号套筒和驱动器之间的相对旋转 当处于去耦状态时，
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公开(公告)号：US07008405B2
公开(公告)日：2006-03-07
申请号：US10471717
申请日：2002-03-26
CPC分类号： A61M5/3158 , A61M5/24 , A61M5/31513 , A61M5/31553 , A61M5/31563 , A61M5/31593 , A61M2005/31518
摘要： Injection devices are known for the self administration of medicament by patients. The medicament is typically contained within a cartridge located within the injection device. It is a problem that injection devices should be small enough to fit into a jacket pocket or a hand bag without difficulty. Also, the injection device must be of a size that enables a piston or similar used to drive the Cartridge bung within the cartridge to be moved both to a maximum dispense position within the cartridge and to be fully withdrawn from the cartridge to allow for replacement of the cartridge. A drive mechanism for an injecting device is disclosed in which the drive mechanism comprises a displaceable dosing spindle 6, a dial dose means 8, a transmission means 10, and a cable means 12, a piston comprising a plurality of nested piston members 30, 32, 34, displacement of the transmission means 10 causing the cable means 12 to move at least one of one of the nested piston members to drive a cartridge bung 18.
摘要翻译： 已知用于患者自身给药的注射装置。 药物通常包含在位于注射装置内的药筒内。 这是一个注射装置应该足够小以难以装入夹克口袋或手提袋的问题。 而且，注射装置必须具有这样的尺寸，使得活塞或类似物能够驱动药筒内的药筒塞被移动到药筒内的最大分配位置，并且完全从药筒中撤出以允许更换 墨盒。 公开了一种用于注射装置的驱动机构，其中驱动机构包括可移动的定量心轴6，拨号剂量装置8，传动装置10和电缆装置12，包括多个嵌套活塞构件30,32 34，传动装置10的位移，导致缆索装置12移动嵌套的活塞件之一中的至少一个以驱动筒塞18。
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