公开(公告)号：US20150320553A1

公开(公告)日：2015-11-12

申请号：US14801713

申请日：2015-07-16

Applicant: Edwards Lifesciences Corporation

Inventor： Mark Chau ,  Marlowe E. Patterson ,  Seung-Beom Yi ,  Stephen C. Geist ,  Travis Oba

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2445 ,  A61F2/246 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0069 ,  A61F2250/006 ,  A61F2250/0063

Abstract: A prosthetic apparatus configured for implantation in the native mitral valve region of the heart includes a main body that is self-expandable from a compressed state to a radially expanded state. The prosthetic apparatus comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body for capturing a native valve leaflet between the anchor and an outer surface of the main body. In one preferred method of implantation, the prosthetic apparatus is rotated within the native mitral valve region such that a portion of the anchor moves horizontally behind adjacent chordae for anchoring the prosthetic apparatus in the native mitral valve.

Abstract translation: 构造成用于植入心脏的天然二尖瓣区域的假体装置包括从压缩状态向径向展开状态自扩张的主体。 假体装置包括耦合到主体并且设置在主体外部的至少一个心室锚，用于捕获锚固体和主体的外表面之间的天然瓣膜。 在一种优选的植入方法中，假体装置在天然二尖瓣区域内旋转，使得锚的一部分水平地移动到相邻的腱索之后，以将假体装置锚定在天然二尖瓣中。

公开(公告)号：US20150216660A1

公开(公告)日：2015-08-06

申请号：US14685489

申请日：2015-04-13

Applicant: Edwards Lifesciences Corporation

Inventor： Rafael Pintor ,  Mark Chau ,  Travis Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

IPC: A61F2/24

CPC classification number: A61F2/2427 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2439 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/005 ,  A61F2250/006

Abstract: A quick-connect heart valve prosthesis that can be quickly and easily implanted is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable coupling stent, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the coupling stent attached thereto. The coupling stent may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes a hollow two-piece handle through which a balloon catheter passes. A valve holder is stored with the heart valve and the handle easily attaches thereto to improve valve preparation steps.

Abstract translation: 提供了可以快速且容易地植入的快速连接的心脏瓣膜假体。 心脏瓣膜包括基本上不可膨胀的不可压缩的人造瓣膜和塑性可扩张的联接支架，从而使得能够在不缝合的情况下连接到环形空间。 可以提供少量的导向缝线用于主动脉瓣取向。 假体瓣膜可以是具有连接有联接支架的缝合环的市售阀。 联接支架可以从锥形展开形状扩展到圆锥形膨胀形状，并且可以包括连接在轴向延伸柱之间的腹板状支柱。 用于展开的系统和方法包括气球导管通过的中空两件式手柄。 与心脏瓣膜一起存储阀保持器，并且手柄容易地附接到其上以改善阀门准备步骤。

公开(公告)号：US08926691B2

公开(公告)日：2015-01-06

申请号：US14025594

申请日：2013-09-12

Applicant: Edwards Lifesciences Corporation

Inventor： Mark Chau ,  Marlowe E. Patterson ,  Seung-Beom Yi ,  Stephen C. Geist ,  Travis Oba

IPC: A61F2/06 ,  A61F2/24 ,  A61F11/00

CPC classification number: A61F2/2412 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2445 ,  A61F2/246 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0069 ,  A61F2250/006 ,  A61F2250/0063

Abstract: Embodiments of an apparatus for treating a deficient mitral valve include an expandable spacer configured for placement between the native leaflets of the mitral valve, the spacer anchorable to a wall of the ventricle. Methods and apparatus for delivering and implanting the prosthetic are also described.

Abstract translation: 用于治疗缺陷型二尖瓣的装置的实施例包括可扩张间隔物，其被配置用于放置在二尖瓣的天然传播片之间，该间隔物可锚定到心室的壁。 还描述了用于递送和植入假体的方法和装置。

公开(公告)号：US20140222136A1

公开(公告)日：2014-08-07

申请号：US14171603

申请日：2014-02-03

Applicant: Edwards Lifesciences Corporation

Inventor： Stephen C. Geist ,  Robert C. Taft ,  Travis Oba ,  Sam Sok ,  Matthew A. Peterson ,  Kevin M. Golemo ,  Mark Chau ,  Seung-Beom Yi

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61B6/4441 ,  A61B8/12 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2436 ,  A61F2/2466 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2250/0018 ,  A61F2250/0029 ,  A61F2250/0069

Abstract: Embodiments of prosthetic valves for implantation within a native mitral valve are provided. One embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve member. In some cases, the prosthetic valves also include ventricular anchors and/or an atrial portion coupled to and disposed outside of the main body. Methods, devices, and systems for delivering such prosthetic valves to the native mitral valve and implanting them therein are also provided.

Abstract translation: 提供了用于植入在天然二尖瓣内的人工瓣膜的实施例。 假体瓣膜的一个实施例包括可径向压缩的主体和单向阀构件。 在一些情况下，假体瓣膜还包括联接到并设置在主体外侧的心室锚和/或心房部分。 还提供了用于将这种假性瓣膜递送到天然二尖瓣并将其植入其中的方法，装置和系统。

公开(公告)号：US20140067054A1

公开(公告)日：2014-03-06

申请号：US14011598

申请日：2013-08-27

Applicant: Edwards Lifesciences Corporation

Inventor： Mark Chau ,  Travis Oba ,  Sergio Delgado ,  Robert C. Taft ,  Stanton J. Rowe ,  Alexander H. Cooper

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2412 ,  A61F2/243 ,  A61F2/2433 ,  A61F2/2442 ,  A61F2/2445 ,  A61F2/2454 ,  A61F2/2457 ,  A61F2/246 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2230/0069 ,  A61F2250/0003

Abstract: This disclosure pertains generally to prosthetic devices and related methods for helping to seal native heart valves and prevent or reduce regurgitation therethrough, as well as devices and related methods for implanting such prosthetic devices. In some cases, a spacer having a single anchor can be implanted within a native heart valve. In some cases, a spacer having dual anchors can be implanted within a native heart valve. In some cases, devices can be used to extend the effective length of a native heart valve leaflet.