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29 条记录 (耗时 0.04 秒)

    Method for obtaining dynamic and structural data pertaining to proteins and protein/ligand complexes
    22.
    发明申请
    Method for obtaining dynamic and structural data pertaining to proteins and protein/ligand complexes 审中-公开
    获得有关蛋白质和蛋白质/配体复合物的动态和结构数据的方法

    公开(公告)号：US20060154323A1

    公开(公告)日：2006-07-13

    申请号：US10517380

    申请日：2003-06-10

    申请人： Jonathan Brown ,  Steven Homans ,  Minn-Chang Cheng ,  Michael Chaykovsky ,  Jenny Murray

    发明人： Jonathan Brown ,  Steven Homans ,  Minn-Chang Cheng ,  Michael Chaykovsky ,  Jenny Murray

    IPC分类号： C12Q1/37 ,  C12Q1/04 ,  G01N33/00 ,  C07C229/02

    CPC分类号： C07B59/008 ,  C07B59/001 ,  C07B2200/05 ,  C07C229/08 ,  C07K14/4702 ,  C07K2299/00 ,  G01N33/6803

    摘要： This invention provides an NMR method for obtaining both entropic and enthalpic data on proteins and protein/ligand complexes which can be used to obtain accurate structural and dynamic data of proteins and protein complexes having a wide range of molecular weights. An embodiment of the invention provides proteins which contain at least one bond vector whose dynamics are to be measured and which is surrounded by NMR inactive nuclei, and amino acids for synthesis of the proteins via chemical means or biological expression. The NMR methods using specifically labeled proteins for analysis result in maximization of the sensitivity and resolution of the NMR experiments, and minimization of the loss of signal due to diffusion.

    摘要翻译： 本发明提供了一种用于获得蛋白质和蛋白质/配体配合物的熵和焓数据的NMR方法，其可用于获得具有宽范围分子量的蛋白质和蛋白质复合物的精确结构和动态数据。 本发明的一个实施方案提供了蛋白质，其含有至少一种键合载体，其动力学将被测量并被NMR无活性核包围，以及用于通过化学方法或生物表达合成蛋白质的氨基酸。 使用特异性标记的蛋白质进行分析的NMR方法导致NMR实验的灵敏度和分辨率的最大化，以及由于扩散引起的信号损失的最小化。

    Apparatus and method for formation evaluation
    23.
    发明申请
    Apparatus and method for formation evaluation 有权
    地层评价装置及方法

    公开(公告)号：US20060137873A1

    公开(公告)日：2006-06-29

    申请号：US11021849

    申请日：2004-12-23

    申请人： Derek Caudwell ,  Anthony Goodwin ,  Martin Trusler ,  Michael Frels ,  Kai Hsu ,  Jonathan Brown ,  Julian Pop ,  Bunker Hill ,  Andrew Kurkjian

    发明人： Derek Caudwell ,  Anthony Goodwin ,  Martin Trusler ,  Michael Frels ,  Kai Hsu ,  Jonathan Brown ,  Julian Pop ,  Bunker Hill ,  Andrew Kurkjian

    IPC分类号： E21B49/08

    CPC分类号： G01N11/16 ,  E21B49/10

    摘要： A viscometer for a down hole tool positionable in a well bore penetrating a subterranean formation is described. The formation contains at least one fluid therein. The down hole tool is adapted to convey at least a portion of the fluid to the viscometer. The viscometer comprises a sensor unit, and at least one magnet. The sensor unit is positionable within the down hole tool and comprises at least two spatially disposed clamps and a wire suspended in tension between the at least two clamps such that the wire is available for interaction with the fluid when the viscometer is positioned within the down hole tool and the down hole tool is positioned within the subterranean formation and receives the fluid from the subterranean formation.

    摘要翻译： 描述了一种位于穿透地层的井眼中的井下工具的粘度计。 地层中含有至少一种流体。 井下工具适于将至少一部分流体输送到粘度计。 粘度计包括传感器单元和至少一个磁体。 传感器单元可定位在井下工具内，并且包括至少两个空间设置的夹具和在至少两个夹子之间张紧地悬挂的线材，使得当粘度计位于下孔内时，该线材可用于与流体相互作用 工具，井下工具位于地下地层内并从地下地层接收流体。

    Resource and utilization management of telecommunication devices
    25.
    发明授权
    Resource and utilization management of telecommunication devices 有权
    电信设备资源利用管理

    公开(公告)号：US08346212B2

    公开(公告)日：2013-01-01

    申请号：US13083339

    申请日：2011-04-08

    申请人： James Breitzman ,  Jonathan Brown

    发明人： James Breitzman ,  Jonathan Brown

    IPC分类号： H04M11/00

    CPC分类号： H04L41/5029 ,  H04L12/14 ,  H04L12/145 ,  H04M15/00 ,  H04M15/43 ,  H04M15/49 ,  H04M15/58 ,  H04M15/765 ,  H04M15/7652 ,  H04M15/80 ,  H04M15/8011 ,  H04M15/8022

    摘要： Methods and systems for resource and utilization management of telecommunications devices within an enterprise, where the enterprise contracts for telecommunications service from one or more service providers, comprising components configured to receive quantity data corresponding to the amount of telecommunications service used by the enterprise per period into a resource management system including a microprocessor executing programmed instructions, group telecommunications devices into pools of shared use for the telecommunications service, the pools of shared use including one or more telecommunication devices, analyze for each telecommunications device telecommunications services plans available from the service providers to determine the total quantity of telecommunications service provided by the service providers and the cost per unit of telecommunications service, select selected telecommunications service plans for each telecommunications device that accommodate a target quantity of projected telecommunications service use per period, and subscribe the telecommunications devices to the selected service plans.

    摘要翻译： 企业内的电信设备的资源和利用管理方法和系统，其中企业从一个或多个服务提供商签约电信服务，其中包括被配置为接收对应于每个时期企业使用的电信服务量的数量数据的组件 资源管理系统，其包括执行编程指令的微处理器，将电信设备组合成用于电信服务的共享使用池，包括一个或多个电信设备的共享使用池，分析每个电信设备可从服务提供商获得的电信服务计划 确定服务提供商提供的电信服务总量和每单位电信业务的成本，选择适应目标量的每个电信设备的选定电信服务计划 预计电话服务使用时间，并将电讯设备订阅所选择的服务计划。

    System and Method for Obtaining Well Fluid Samples
    27.
    发明申请
    System and Method for Obtaining Well Fluid Samples 审中-公开
    用于获得井流体样品的系统和方法

    公开(公告)号：US20070236215A1

    公开(公告)日：2007-10-11

    申请号：US11307320

    申请日：2006-02-01

    申请人： Martin Innes ,  David MacWilliam ,  Javed Shafi ,  Jonathan Brown

    发明人： Martin Innes ,  David MacWilliam ,  Javed Shafi ,  Jonathan Brown

    IPC分类号： G01V3/18

    CPC分类号： E21B49/082

    摘要： A system and method facilitates the sampling of well fluid during a well logging operation. A sampling tool may be coupled into a logging tool string and delivered downhole into a wellbore. At a desired location within the wellbore, the sampling tool may be triggered to intake a well fluid sample. The well fluid sample is maintained in the sampling tool in a substantially pristine condition for retrieval to a desired location for analysis.

    摘要翻译： 在测井操作期间，系统和方法有利于井液的采样。 采样工具可以耦合到测井工具串中并在井下传送到井筒中。 在井筒内的期望位置处，可以触发采样工具以摄取井流体样品。 井液样品以基本上原始状态保持在采样工具中，用于检索到期望的位置用于分析。

    Wellbore formation evaluation system and method
    28.
    发明申请
    Wellbore formation evaluation system and method 有权
    井眼形成评价体系及方法

    公开(公告)号：US20070114021A1

    公开(公告)日：2007-05-24

    申请号：US11284077

    申请日：2005-11-21

    申请人： Jonathan Brown ,  Danny Hlavinka ,  David Ayers

    发明人： Jonathan Brown ,  Danny Hlavinka ,  David Ayers

    IPC分类号： E21B49/10

    CPC分类号： E21B49/10 ,  E21B36/001 ,  E21B47/011

    摘要： A formation evaluation tool positionable in a wellbore penetrating a subterranean formation is provided. The formation evaluation tool includes a cooling system adapted to pass a cooling fluid near electronics in the formation evaluation tool whereby heat is dissipated therefrom, the electronics has at least one gauge, a fluid communication device having an inlet adapted to receive the formation fluid and a flowline operatively connected to the fluid communication device and the gauge for placing the formation fluid in fluid communication therewith whereby properties of the formation fluid are determined. The formation evaluation tool may also be provided with a plurality of sample chambers operatively connected to the flowline for collecting at least a portion of the formation fluid and a pressure compensator in fluid communication with the wellbore and operatively connected to the plurality of sample chambers for applying pressure to the sample chambers whereby pressure is balanced therebetween.

    摘要翻译： 提供一种定位在穿透地下地层的井眼中的地层评价工具。 地层评估工具包括冷却系统，该冷却系统适于使地层评估工具内的电子设备附近的冷却流体通过，由此热量从其中消散，电子设备具有至少一个量规，流体连通装置具有适于容纳地层流体的入口和 流体线可操作地连接到流体连通装置和用于将地层流体与流体连通的计量器，从而确定地层流体的特性。 地层评估工具还可以设置有多个样品室，其可操作地连接到流动线，用于收集地层流体的至少一部分和与井眼流体连通的压力补偿器，并可操作地连接到多个样品室以施加 对样品室施加压力，由此在它们之间平衡压力。