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公开(公告)号：US20050100595A1
公开(公告)日：2005-05-12
申请号：US11002842
申请日：2004-11-30
申请人： Edith Mathiowitz , Christopher Thanos , Zhi Liu
发明人： Edith Mathiowitz , Christopher Thanos , Zhi Liu
IPC分类号： A23P1/02 , A23P1/06 , A61K9/14 , A61K9/16 , A61K9/51 , A61K9/52 , B01D9/00 , B01D9/02 , B01J13/04 , B01J13/06 , B01J13/14 , A61K9/54
CPC分类号： A61K9/5138 , A61K9/14 , A61K9/146 , A61K9/1688 , A61K9/1694 , A61K9/5146 , A61K9/5192 , B01D9/00 , B01J13/06 , Y10T428/2982 , Y10T428/2985 , Y10T428/2989 , Y10T428/31685 , Y10T428/31696
摘要： The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is provided. The invention also relates to products of micronized hydrophobic drugs and related methods of use.
摘要翻译： 本发明涉及与疏水性药物的微粉化相关的方法和产品。 提供了使用一组包括水溶液的溶液来微粉化疏水性药物的方法。 本发明还涉及微粉化疏水药物的产品和相关使用方法。
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公开(公告)号：US06746635B2
公开(公告)日：2004-06-08
申请号：US10215208
申请日：2002-08-08
申请人： Edith Mathiowitz , Christopher Thanos , Zhi Liu
发明人： Edith Mathiowitz , Christopher Thanos , Zhi Liu
IPC分类号： B01J1302
CPC分类号： A61K9/5138 , A61K9/14 , A61K9/146 , A61K9/1688 , A61K9/1694 , A61K9/5146 , A61K9/5192 , B01D9/00 , B01J13/06 , Y10T428/2982 , Y10T428/2985 , Y10T428/2989 , Y10T428/31685 , Y10T428/31696
摘要： The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is provided. The invention also relates to products of micronized hydrophobic drugs and related methods of use.
摘要翻译： 本发明涉及与疏水性药物的微粉化相关的方法和产品。 提供了使用一组包括水溶液的溶液来微粉化疏水性药物的方法。 本发明还涉及微粉化疏水药物的产品和相关使用方法。
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公开(公告)号：US20090075375A1
公开(公告)日：2009-03-19
申请号：US12210696
申请日：2008-09-15
申请人： Robert Bartlett Elliott , Stephen John Martin Skinner , Livia Del Carmen Escobar Orellana , Christopher Thanos , Thorsten Gorba
发明人： Robert Bartlett Elliott , Stephen John Martin Skinner , Livia Del Carmen Escobar Orellana , Christopher Thanos , Thorsten Gorba
IPC分类号： C12N5/06
CPC分类号： C12N5/0018 , C12N2502/08
摘要： The present invention is directed to the use of choroids plexus cells and/or choroids plexus conditioned media for enhancing the growth, survival and/or maintenance of function of non-choroid plexus cells grown in long term or short term culture.
摘要翻译： 本发明涉及脉络丛细胞和/或脉络丛丛状培养基用于增强长期或短期培养中生长的非脉络丛神经细胞的生长，存活和/或维持功能的用途。
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公开(公告)号：US08524829B2
公开(公告)日：2013-09-03
申请号：US12140701
申请日：2008-06-17
申请人： Edith Mathiowitz , Christopher Thanos , Zhi Liu
发明人： Edith Mathiowitz , Christopher Thanos , Zhi Liu
CPC分类号： A61K9/5138 , A61K9/14 , A61K9/146 , A61K9/1688 , A61K9/1694 , A61K9/5146 , A61K9/5192 , B01D9/00 , B01J13/06 , Y10T428/2982 , Y10T428/2985 , Y10T428/2989 , Y10T428/31685 , Y10T428/31696
摘要： The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is provided. The invention also relates to products of micronized hydrophobic drugs and related methods of use.
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公开(公告)号：US08129186B2
公开(公告)日：2012-03-06
申请号：US11911961
申请日：2006-04-18
申请人： Robert Bartlett Elliott , Stephen John Martin Skinner , Livia Del Carmen Escobar Orellana , Christopher Thanos
发明人： Robert Bartlett Elliott , Stephen John Martin Skinner , Livia Del Carmen Escobar Orellana , Christopher Thanos
IPC分类号： C12N5/02
CPC分类号： C12N5/0018 , C12N2502/08
摘要： The present invention is directed to the use of choroid plexus cells and/or choroid plexus conditioned media for enhancing the growth, survival and/or maintenance of function of non-choroid plexus cells grown in long term or short term culture.
摘要翻译： 本发明涉及脉络丛神经细胞和/或脉络丛条件培养基用于增强长期或短期培养中生长的非脉络丛神经细胞的生长，存活和/或维持功能的用途。
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公开(公告)号：US20080119909A1
公开(公告)日：2008-05-22
申请号：US11682810
申请日：2007-03-06
申请人： Stephen John Martin Skinner , Marilyn Sandra Geaney , Paul Lip Jin Tan , Robert Keith Shepherd , Lisa Narelle Pettingill , Jacqueline Kate Andrew , Christopher Thanos , Dwaine Emerich
发明人： Stephen John Martin Skinner , Marilyn Sandra Geaney , Paul Lip Jin Tan , Robert Keith Shepherd , Lisa Narelle Pettingill , Jacqueline Kate Andrew , Christopher Thanos , Dwaine Emerich
IPC分类号： A61F2/18
CPC分类号： A61K35/30
摘要： The present invention is directed to the prevention or treatment of sensorineural hearing loss by administering a therapeutically effective amount of an implantable composition comprising encapsulated living choroid plexus cells.
摘要翻译： 本发明涉及通过施用治疗有效量的包含囊状活脉脉丛神经细胞的可植入组合物来预防或治疗感觉神经性听力损失。
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27.发明申请公开(公告)号：US20060029590A1
公开(公告)日：2006-02-09
申请号：US11149513
申请日：2005-06-10
申请人： Christopher Thanos , Edwin Madison
发明人： Christopher Thanos , Edwin Madison
CPC分类号： C12N9/6421 , A61K38/00 , C12N9/6494 , C12Y304/24011
摘要： Administration of recombinant, truncated mammalian NEP or certain bacterial homologues of this protein is therapeutically effective in the treatment of inflammatory bowel disease.
摘要翻译： 重组，截短的哺乳动物NEP或该蛋白质的某些细菌同系物的施用在治疗炎症性肠病中是治疗有效的。
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公开(公告)号：US06824791B2
公开(公告)日：2004-11-30
申请号：US10758990
申请日：2004-01-16
申请人： Edith Mathiowitz , Christopher Thanos , Zhi Liu
发明人： Edith Mathiowitz , Christopher Thanos , Zhi Liu
IPC分类号： A61K952
CPC分类号： A61K9/5138 , A61K9/14 , A61K9/146 , A61K9/1688 , A61K9/1694 , A61K9/5146 , A61K9/5192 , B01D9/00 , B01J13/06 , Y10T428/2982 , Y10T428/2985 , Y10T428/2989 , Y10T428/31685 , Y10T428/31696
摘要： The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is provided. The invention also relates to products of micronized hydrophobic drugs and related methods of use.
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