公开(公告)号：US20130141098A1

公开(公告)日：2013-06-06

申请号：US13753894

申请日：2013-01-30

申请人： Jun Bao ,  David Faul ,  Ralf Ladebeck ,  John Thomas Pawlak ,  Elmar Rummert ,  Charles C. Watson

发明人： Jun Bao ,  David Faul ,  Ralf Ladebeck ,  John Thomas Pawlak ,  Elmar Rummert ,  Charles C. Watson

IPC分类号： G01R33/48

CPC分类号： G01R33/58 ,  G01R33/48 ,  G01R33/481 ,  G01R33/4812 ,  G01T1/1603 ,  G01T7/005

摘要： A phantom for co-registering a magnetic resonance image and a nuclear medical image is disclosed. The phantom includes a longitudinal member having a first end cap and a second end cap and a chamber contained within the longitudinal member. The chamber contains a fluid for producing a first image using a first imaging modality. The phantom further includes a first rod disposed within the chamber of the longitudinal member. The first rod contains a radioactive substance for producing a second image using a second imaging modality.

摘要翻译： 公开了用于共同配准磁共振图像和核医学图像的体模。 该体模包括具有第一端盖和第二端盖以及容纳在纵向构件内的室的纵向构件。 该腔室包含用于使用第一成像模态产生第一图像的流体。 体模还包括设置在纵向构件的腔室内的第一杆。 第一杆包含用于使用第二成像模态产生第二图像的放射性物质。

公开(公告)号：US08299438B2

公开(公告)日：2012-10-30

申请号：US12458575

申请日：2009-07-16

申请人： Matthias Fenchel ,  Ralf Ladebeck ,  Christian J. Michel ,  Charles C. Watson

发明人： Matthias Fenchel ,  Ralf Ladebeck ,  Christian J. Michel ,  Charles C. Watson

IPC分类号： G06F17/10

CPC分类号： G01R33/481 ,  A61B6/037 ,  A61B6/5235 ,  A61B6/5247 ,  G01R33/5608 ,  G06T11/005

摘要： Example embodiments are directed to a method of correcting attenuation in a magnetic resonance (MR) scanner and a positron emission tomography (PET) unit. The method includes acquiring PET sinogram data of an object within a field of view of the PET unit. The method further includes producing an attenuation map based on a maximum likelihood expectation maximization (MLEM) of a parameterized model instance and the PET sinogram data.

摘要翻译： 示例性实施例涉及一种校正磁共振（MR）扫描仪和正电子发射断层摄影（PET）单元中的衰减的方法。 该方法包括在PET单元的视野范围内获取物体的PET正弦图数据。 该方法还包括基于参数化模型实例的最大似然期望最大化（MLEM）和PET正弦图数据产生衰减图。

公开(公告)号：US08198893B2

公开(公告)日：2012-06-12

申请号：US12566837

申请日：2009-09-25

申请人： Sascha Fath ,  Ralf Ladebeck

发明人： Sascha Fath ,  Ralf Ladebeck

IPC分类号： G01V3/00

CPC分类号： G01R33/385 ,  G01R33/481

摘要： In a method for designing a gradient coil composed of multiple sub-coils, parameters representing the structure of the gradient coil are varied, and the variation that produces an optimized electrical field generated by the gradient coil is determined. The final design of the gradient coil embodies those parameters that produced the optimal electrical field. In a method for manufacturing a gradient coil, the gradient coil is manufactured according to the final design. A gradient coil manufactured according to the invention has a gradient conductor configuration that optimizes the electrical field generated by the gradient coil. A magnetic resonance apparatus, and a combined positron emission tomography/magnetic resonance apparatus, embodies such a gradient coil.

摘要翻译： 在用于设计由多个子线圈组成的梯度线圈的方法中，改变表示梯度线圈的结构的参数，并且确定由梯度线圈产生的优化电场的变化。 梯度线圈的最终设计体现了产生最佳电场的那些参数。 在制造梯度线圈的方法中，根据最终设计制造梯度线圈。 根据本发明制造的梯度线圈具有优化梯度线圈产生的电场的梯度导体配置。 磁共振装置和组合的正电子发射断层摄影/磁共振装置体现了这种梯度线圈。

公开(公告)号：US08180128B2

公开(公告)日：2012-05-15

申请号：US12219613

申请日：2008-07-24

申请人： Thorsten Feiweier ,  Ralf Ladebeck ,  Diana Martin ,  Hartwig Newiger ,  Josef Pfeuffer ,  Michael Szimtenings ,  Harald Werthner

发明人： Thorsten Feiweier ,  Ralf Ladebeck ,  Diana Martin ,  Hartwig Newiger ,  Josef Pfeuffer ,  Michael Szimtenings ,  Harald Werthner

IPC分类号： G01R33/56 ,  G01R33/54

CPC分类号： A61B6/032 ,  A61B5/11 ,  A61B5/7285 ,  A61B6/037 ,  A61B6/541 ,  A61B8/00 ,  A61B8/4416 ,  G06F19/00

摘要： A method is disclosed for recording measured data of a patient while taking account of movement operations by way of a medical device that is designed both for recording movement-related measured data, in particular measured data of high temporal resolution and/or measured data that can be interpolated with regard to movement operations, with the aid of an imaging method and/or by means of at least one sensor element, and also for recording nuclear medicine measured data, in particular of lower temporal resolution. In at least one embodiment, the method includes recording nuclear medicine measured data with the aid of the medical device; simultaneously recording movement-related measured data with the aid of the medical device; determining at least one item of movement information relating to at least one movement operation of the patient and/or in the body of the patient by evaluating at least a portion of the recorded measured data of high temporal resolution on the part of a computing device of the medical device; and adapting at least one item of attenuation correction information available for the computing device and serving for reconstructing the nuclear medicine measured data, doing so as a function of the at least one determined item of movement information.

摘要翻译： 公开了一种用于记录患者的测量数据的方法，同时考虑到通过设计用于记录运动相关测量数据的医疗设备，特别是高时间分辨率的测量数据和/或可测量数据的测量数据， 借助于成像方法和/或通过至少一个传感器元件，以及用于记录核医学测量数据，特别是用于记录较低时间分辨率的内插关于移动操作。 在至少一个实施例中，该方法包括借助医疗装置记录核医学测量数据; 借助医疗设备同时记录运动相关测量数据; 通过在计算设备的一部分上评估所记录的高时间分辨率的测量数据的至少一部分来确定与患者的至少一个移动操作和/或患者身体有关的至少一个移动信息项 医疗器械; 以及修改可用于所述计算设备的至少一项衰减校正信息，并且用于重构所述核医学测量数据，作为所述至少一个确定的运动信息项的函数。

公开(公告)号：US20120089007A1

公开(公告)日：2012-04-12

申请号：US12902185

申请日：2010-10-12

申请人： James Frank Caruba ,  Ralf Ladebeck ,  Ralph Oppelt ,  Patanit Sanpitak

发明人： James Frank Caruba ,  Ralf Ladebeck ,  Ralph Oppelt ,  Patanit Sanpitak

IPC分类号： A61B5/055

CPC分类号： G01R33/481

摘要： Timing in a medical imaging system. The system comprises a magnetic resonance imaging (MRI) subsystem and a non-MRI subsystem. Operation of the non-MRI subsystem involves a timing signal within a radio frequency (RF) cabin of the MRI subsystem. Basing each non-MRI subsystem timing signal on a time base common between the MRI subsystem and the non-MRI subsystem. The non-MRI subsystem can be a medical imaging subsystem. The non-MRI medical imaging subsystem can be a positron emission tomography (PET) subsystem. Each non-MRI subsystem timing signal that based on the common time base can be created using the same model of equipment used for creating timing signals in the MRI subsystem. At least one stage of the non-MRI subsystem timing signal based on the common time base can be created using the same equipment used for creating timing signals in the MRI subsystem.

摘要翻译： 医学影像系统的时间安排 该系统包括磁共振成像（MRI）子系统和非MRI子系统。 非MRI子系统的操作涉及MRI子系统的射频（RF）舱内的定时信号。 在MRI子系统和非MRI子系统之间共同的时基上，按照每个非MRI子系统定时信号。 非MRI子系统可以是医学成像子系统。 非MRI医学成像子系统可以是正电子发射断层摄影（PET）子系统。 可以使用与用于在MRI子系统中创建定时信号相同的设备模型来创建基于公共时基的每个非MRI子系统定时信号。 可以使用用于在MRI子系统中创建定时信号的相同设备来创建基于公共时基的非MRI子系统定时信号的至少一个阶段。

公开(公告)号：US20120076371A1

公开(公告)日：2012-03-29

申请号：US12888504

申请日：2010-09-23

申请人： James Frank Caruba ,  Ralf Ladebeck

发明人： James Frank Caruba ,  Ralf Ladebeck

IPC分类号： G06K9/00 ,  G06K19/067 ,  G06K19/06 ,  G12B13/00

CPC分类号： A61B6/4417 ,  A61B5/0035 ,  A61B5/055 ,  A61B6/037 ,  A61B6/583

摘要： The invention relates to calibration phantoms used in connection with medical imaging devices such as PET, MR, etc., and particularly in connection with hybrid systems such as MR/PET systems. In some cases, the phantoms have distinguishable, machine-readable identification features that allow the imaging system to identify them automatically, without operator intervention. In other cases, even where the phantoms do not have such distinguishable, machine-readable identification features, if the imaging system is appropriately configured with cameras and/or appropriate image analysis software, the imaging system can still identify the phantoms automatically.

摘要翻译： 本发明涉及与诸如PET，MR等医学成像装置相关联使用的校准体模，并且特别涉及诸如MR / PET系统的混合系统。 在某些情况下，幻影具有可区分的机器可读识别特征，允许成像系统自动识别它们，而无需操作人员的干预。 在其他情况下，即使幻影没有这种可区分的机器可读识别特征，如果成像系统被适当地配置有照相机和/或适当的图像分析软件，则成像系统仍然可以自动识别幻影。

公开(公告)号：US20110309251A1

公开(公告)日：2011-12-22

申请号：US13160616

申请日：2011-06-15

申请人： Matthias Fenchel ,  Ralf Ladebeck

发明人： Matthias Fenchel ,  Ralf Ladebeck

IPC分类号： G01T1/164 ,  G01T1/20

CPC分类号： G01R33/481 ,  A61B6/037 ,  A61B6/4417 ,  A61B6/583 ,  G06T11/005

摘要： A method is disclosed for determining radiation attenuation as a result of an object in a positron emission tomography scanner. In at least one embodiment, a phantom object is arranged in the positron emission tomography scanner during the method. First raw radiation data of the phantom object is acquired while the object is not arranged in the positron emission tomography scanner. A first image of the phantom object is calculated from the first raw radiation data. The object then is arranged in the positron emission tomography scanner (2) and preliminary radiation attenuation of the object is identified. Second raw radiation data of the phantom object is acquired while the object is arranged in the positron emission tomography scanner. A second image of the phantom object is calculated from the second raw radiation data taking into account the preliminary radiation attenuation. The radiation attenuation is determined on the basis of the first image and the second image.

摘要翻译： 公开了一种用于确定作为正电子发射断层摄影扫描仪中的物体的结果的辐射衰减的方法。 在至少一个实施例中，在该方法期间，在正电子发射断层摄影扫描器中布置幻影物体。 当物体未排列在正电子发射断层摄影扫描器中时，获取幻影物体的第一原始辐射数据。 从第一个原始辐射数据计算幻影物体的第一个图像。 物体然后被布置在正电子发射断层扫描仪（2）中，并且识别对象的初步辐射衰减。 当物体布置在正电子发射断层扫描仪中时，获取体模对象的第二原始辐射数据。 考虑到初步辐射衰减，从第二原始辐射数据计算幻影物体的第二图像。 基于第一图像和第二图像确定辐射衰减。

公开(公告)号：US20110187364A1

公开(公告)日：2011-08-04

申请号：US13015065

申请日：2011-01-27

申请人： Jan Ole BLUMHAGEN ,  Matthias Fenchel ,  Ralf Ladebeck

发明人： Jan Ole BLUMHAGEN ,  Matthias Fenchel ,  Ralf Ladebeck

IPC分类号： G01R33/48

CPC分类号： G01R33/481 ,  G01R33/56563

摘要： A method is disclosed for determining a location of a subarea of an area under examination in a magnetic resonance system. The subarea is arranged at the edge of a field-of-view of the magnetic resonance system. In at least one embodiment of the method, at least one slice position is determined for an MR image in which the B0 field at the edge of the MR image satisfies a homogeneity value. For the slice position determined an MR image is acquired which contains the subarea at the edge of the field-of-view and the location of the subarea of the object under examination is determined through the location of the subarea in the MR image.

摘要翻译： 公开了一种用于确定磁共振系统中被检查区域的子区域的位置的方法。 子区域布置在磁共振系统的视野的边缘。 在该方法的至少一个实施例中，为MR图像确定至少一个切片位置，其中MR图像边缘处的B0场满足均匀性值。 对于确定的切片位置，获取包含在视场边缘处的子区域的MR图像，并且通过MR图像中的子区域的位置来确定被检查对象的子区域的位置。

公开(公告)号：US07888632B2

公开(公告)日：2011-02-15

申请号：US12564685

申请日：2009-09-22

申请人： Ralf Ladebeck ,  Christian J. Michel ,  Charles C. Watson

发明人： Ralf Ladebeck ,  Christian J. Michel ,  Charles C. Watson

IPC分类号： G01T1/161

CPC分类号： G01R33/481

摘要： A method for co-registering attenuation data of MR coils in a MR/PET imaging system with PET emission data includes computing a likelihood of PET emission data on a grid in a parameter space based on an algorithm, wherein the algorithm defines L(λ, μbody, μcoils{p}) as a log-likelihood of measured PET data, where λ is an emitter distribution (image), μbody is a known linear attenuation coefficient (LAC) distribution of the body from MRI, μcoils is a linear attenuation coefficient map of MRI coils, and {p} is a set of parameters governing the position of each coil, wherein if μcoils is assumed, then λ can be reconstructed and forward projected and L can be computed. The method includes adjusting the estimated position of the MR coils to maximize the likelihood of emission data based on the computed L.

摘要翻译： 在具有PET发射数据的MR / PET成像系统中共同记录MR线圈的衰减数据的方法包括基于算法计算参数空间中的网格上的PET发射数据的可能性，其中所述算法定义L（λ， μbody，μcoils{p}）作为测量PET数据的对数似然度，其中λ是发射体分布（图像），μbody是来自MRI的身体的已知线性衰减系数（LAC）分布，μ线圈是线性衰减系数 MRI线圈图，{p}是控制每个线圈位置的一组参数，其中如果假设为μcoils，则可以重建λ并且向前投影，并且可以计算L。 该方法包括调整MR线圈的估计位置，以使基于计算出的L的发射数据的可能性最大化。

公开(公告)号：US20110015904A1

公开(公告)日：2011-01-20

申请号：US12458575

申请日：2009-07-16

申请人： Matthias Fenchel ,  Ralf Ladebeck ,  Christian J. Michel ,  Charles C. Watson

发明人： Matthias Fenchel ,  Ralf Ladebeck ,  Christian J. Michel ,  Charles C. Watson

IPC分类号： G06F17/10

CPC分类号： G01R33/481 ,  A61B6/037 ,  A61B6/5235 ,  A61B6/5247 ,  G01R33/5608 ,  G06T11/005

摘要： Example embodiments are directed to a method of correcting attenuation in a magnetic resonance (MR) scanner and a positron emission tomography (PET) unit. The method includes acquiring PET sinogram data of an object within a field of view of the PET unit. The method further includes producing an attenuation map based on a maximum likelihood expectation maximization (MLEM) of a parameterized model instance and the PET sinogram data.

摘要翻译： 示例性实施例涉及一种校正磁共振（MR）扫描仪和正电子发射断层摄影（PET）单元中的衰减的方法。 该方法包括在PET单元的视野范围内获取物体的PET正弦图数据。 该方法还包括基于参数化模型实例的最大似然期望最大化（MLEM）和PET正弦图数据产生衰减图。