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公开(公告)号：US20130129733A1
公开(公告)日：2013-05-23
申请号：US13668064
申请日：2012-11-02
Applicant: Genentech, Inc.
Inventor： Weilan Ye , Mark S. Dennis , Jill Fredrickson
IPC: C07K16/18 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/395 , A61K45/06
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
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公开(公告)号：US10941199B2
公开(公告)日：2021-03-09
申请号：US15957157
申请日：2018-04-19
Applicant: Genentech, Inc.
Inventor： Liping L. Sun , Yvonne Man-Yee Chen , Mark S. Dennis , Allen J. Ebens, Jr. , Andrew Polson
Abstract: The invention provides anti-CD79b antibodies and methods of using the same.
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公开(公告)号：US20180327492A1
公开(公告)日：2018-11-15
申请号：US15957157
申请日：2018-04-19
Applicant: Genentech, Inc.
Inventor： Liping L. Sun , Yvonne Man-Yee Chen , Mark S. Dennis , Allen J. Ebens, JR. , Andrew Polson
CPC classification number: C07K16/2803 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2809 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/55 , C07K2317/622 , C07K2317/92
Abstract: The invention provides anti-CD79b antibodies and methods of using the same.
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公开(公告)号：US20160185874A1
公开(公告)日：2016-06-30
申请号：US14825114
申请日：2015-08-12
Applicant: GENENTECH, INC.
Inventor： Mark S. Dennis
CPC classification number: C07K16/3015 , A61K47/6811 , A61K47/6843 , A61K47/6849 , A61K47/6855 , A61K49/0032 , A61K49/0056 , A61K49/0058 , A61K2039/505 , C07K7/08 , C07K16/2863 , C07K16/32 , C07K16/36 , C07K2317/55 , C07K2317/92 , C07K2317/94
Abstract: Peptide ligands having affinity for serum albumin are useful for tumor targeting. Conjugate molecules comprising a serum albumin binding peptide fused to a biologically active molecule demonstrate modified pharmacokinetic properties as compared with the biologically active molecule alone, including tissue (e.g., tumor) uptake, infiltration, and diffusion.
Abstract translation: 对血清白蛋白具有亲和力的肽配体可用于肿瘤靶向。 与生物活性分子融合的包含血清白蛋白结合肽的缀合物分子与单独的生物活性分子（包括组织（例如肿瘤）摄取，浸润和扩散）相比显示出修饰的药代动力学性质。
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公开(公告)号：US20140227258A1
公开(公告)日：2014-08-14
申请号：US14212854
申请日：2014-03-14
Applicant: Genentech, Inc.
Inventor： Mark S. Dennis , Karen Billeci , Judy Young , Zhong Zheng
IPC: C07K16/32
Abstract: The invention provides therapeutic anti-c-met antibodies, and compositions comprising and methods of using these antibodies.
Abstract translation: 本发明提供治疗性抗c-met抗体，以及包含使用这些抗体的组合物。
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Patent Agency Ranking
公开(公告)号：US20130324704A1
公开(公告)日：2013-12-05
申请号：US13944538
申请日：2013-07-17
Applicant: Genentech, Inc.
Inventor： Weilan YE , Mark S. Dennis , Jill Fredrickson
IPC: C07K16/22
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
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公开(公告)号：US20130287779A1
公开(公告)日：2013-10-31
申请号：US13919629
申请日：2013-06-17
Applicant: Genentech, Inc.
Inventor： Weilan YE , Mark S. Dennis , Jill Fredrickson
IPC: C07K16/46 , A61K45/06 , A61K39/395 , A61K31/519 , A61K31/282 , A61K31/337 , C07K16/22 , A61K31/513
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
Abstract translation: 本发明涉及EGFL7的抗体及其用途。
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公开(公告)号：US20230002506A1
公开(公告)日：2023-01-05
申请号：US17930018
申请日：2022-09-06
Applicant: Genentech, Inc
Inventor： Xiaocheng CHEN , Mark S. Dennis , Allen J. Ebens, JR. , Robert F. Kelley , Mary A. Mathieu , Liping L. Sun
IPC: C07K16/32 , A61K45/06 , C07K16/28 , A61K31/573 , A61K39/395 , C07K16/30 , A61K47/68 , A61K39/00
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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公开(公告)号：US10808036B2
公开(公告)日：2020-10-20
申请号：US15614149
申请日：2017-06-05
Applicant: Genentech, Inc.
Inventor： Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S. Dennis , James A. Ernst , Ryan J. Watts , Gregory A. Lazar
Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
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公开(公告)号：US20180106809A1
公开(公告)日：2018-04-19
申请号：US15849962
申请日：2017-12-21
Applicant: Genentech, Inc.
Inventor： Mark S. Dennis , Bonnee Rubinfeld , Paul Polakis , Aya Jakobovits
IPC: G01N33/574 , A61K47/68 , A61K49/00
CPC classification number: G01N33/57434 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6851 , A61K47/6869 , A61K47/6871 , A61K49/0002 , A61K49/0058 , A61K51/1045 , A61K51/1072 , A61K2039/505 , C07K16/30 , C07K16/3069 , C07K16/40 , C07K17/00 , C07K2317/24 , C07K2317/31 , C07K2317/515 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/92
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided.
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