公开(公告)号：US09895450B2

公开(公告)日：2018-02-20

申请号：US14945716

申请日：2015-11-19

Applicant: Genentech, Inc.

Inventor： Eric J. Brown ,  John Flygare ,  Wouter Hazenbos ,  Sophie M. Lehar ,  Sanjeev Mariathasan ,  John Hiroshi Morisaki ,  Thomas H. Pillow ,  Leanna Staben ,  Richard Vandlen ,  Klaus Koefoed ,  Magnus Strandh ,  Peter S. Andersen

IPC: A61K39/395 ,  A61K47/48 ,  C07K16/12 ,  A61K31/395 ,  A61K31/4375 ,  A61K31/439 ,  A61K31/4436 ,  A61K31/4709 ,  A61K31/7048 ,  A61K31/7056 ,  A61K38/12

CPC classification number: A61K47/6849 ,  A61K31/395 ,  A61K31/4375 ,  A61K31/439 ,  A61K31/4436 ,  A61K31/4709 ,  A61K31/7048 ,  A61K31/7056 ,  A61K38/12 ,  A61K47/6801 ,  A61K47/6803 ,  A61K47/6809 ,  A61K47/6835 ,  A61K47/6851 ,  C07K16/1271 ,  C07K2317/21 ,  C07K2317/522 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/624 ,  C07K2317/92

Abstract: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.

公开(公告)号：US09803002B2

公开(公告)日：2017-10-31

申请号：US14292289

申请日：2014-05-30

Applicant: Genentech, Inc.

Inventor： Eric J. Brown ,  Martine Darwish ,  John Flygare ,  Wouter Hazenbos ,  Byoung Chul Lee ,  Sophie M. Lehar ,  Sanjeev Mariathasan ,  John Hiroshi Morisaki ,  Thomas H. Pillow ,  Leanna Staben ,  Richard Vandlen ,  Klaus Koefoed ,  Magnus Strandh ,  Peter S. Andersen

IPC: A61K39/40 ,  C07K16/12 ,  A61K31/5386 ,  A61K45/06 ,  A61K31/4025 ,  A61K47/68

CPC classification number: C07K16/1271 ,  A61K31/4025 ,  A61K31/5386 ,  A61K39/40 ,  A61K45/06 ,  A61K47/6809 ,  A61K47/6835 ,  C07K2317/21 ,  C07K2317/522 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/624 ,  C07K2317/92

Abstract: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.

公开(公告)号：US09399673B2

公开(公告)日：2016-07-26

申请号：US13786206

申请日：2013-03-05

Applicant: Genentech, Inc. ,  AIMM Therapeutics B.V.

Inventor： Tim Beaumont ,  Mark Jeroen Kwakkenbos ,  Eric J. Brown ,  John Hiroshi Morisaki ,  Wouter L. W. Hazenbos ,  Sanjeev Mariathasan ,  Kimberly Kajihara ,  Yi Xia

IPC: C07K16/12

CPC classification number: G01N33/5091 ,  C07K16/1271 ,  C07K16/1278 ,  C07K2317/21 ,  C07K2317/52 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  G01N33/6854 ,  G01N33/6893 ,  G01N2469/10 ,  G01N2800/26

Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.

公开(公告)号：US20140356376A1

公开(公告)日：2014-12-04

申请号：US14292289

申请日：2014-05-30

Applicant: Genentech, Inc.

Inventor： Eric J. Brown ,  Martine Darwish ,  John Flygare ,  Wouter Hazenbos ,  Byoung Chul Lee ,  Sophie M. Lehar ,  Sanjeev Mariathasan ,  John Hiroshi Morisaki ,  Thomas H. Pillow ,  Leanna Staben ,  Richard Vandlen ,  Klaus Koefoed ,  Magnus Strandh ,  Peter S. Andersen

IPC: C07K16/12 ,  A61K31/4025 ,  A61K47/48 ,  A61K45/06 ,  A61K39/40 ,  A61K31/5386

CPC classification number: C07K16/1271 ,  A61K31/4025 ,  A61K31/5386 ,  A61K39/40 ,  A61K45/06 ,  A61K47/6809 ,  A61K47/6835 ,  C07K2317/21 ,  C07K2317/522 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/624 ,  C07K2317/92

Abstract: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.