利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

27 条记录 (耗时 0.039 秒)

    Percutaneous controlled releasing material using nano-sized polymer particles and external application agent containing the same
    21.
    发明申请
    Percutaneous controlled releasing material using nano-sized polymer particles and external application agent containing the same 审中-公开
    使用纳米尺寸聚合物颗粒的经皮控制释放材料和含有其的外用施用剂

    公开(公告)号：US20090232855A1

    公开(公告)日：2009-09-17

    申请号：US09878712

    申请日：2001-06-11

    申请人： Sun Sang Kwon ,  Byung Hee Yoo ,  Yoon Sung Nam ,  Bae Hwan Kim ,  Bong Seok Ku ,  Sang Hoon Han ,  Ih Seop Chang ,  Jong Suk Lee

    发明人： Sun Sang Kwon ,  Byung Hee Yoo ,  Yoon Sung Nam ,  Bae Hwan Kim ,  Bong Seok Ku ,  Sang Hoon Han ,  Ih Seop Chang ,  Jong Suk Lee

    IPC分类号： A61K8/02 ,  A61K9/14

    CPC分类号： A61K9/5138

    摘要： A percutaneous releasing material and agent having characteristics that include a high stability of an active agent in the formulation, a high topical absorption rate, decreased irritation on the skin, and an increased tactile comfort. The percutaneous releasing material incorporates an external application agent composition that is prepared by using nanometer-sized polymer particles, i.e., particles having a size or diameter between approximately 1 nm and approximately 500 nm, and more preferably having a size between about 30 nm and about 150 nm. Further, the percutaneous releasing material and agent according to the present invention incorporate polymer particles that preferably contain a physiologically active agent that more readily penetrates through the stratum corneum to the upper layer of the dermis, whereby the physiologically active agent is effused into the skin while staying in the upper layer of dermis.

    摘要翻译： 具有包含制剂中活性剂高稳定性，高局部吸收率，对皮肤刺激性降低以及增加的触觉舒适度的特征的经皮释放材料和试剂。 经皮释放材料包含通过使用纳米尺寸聚合物颗粒制备的外用施用剂组合物，即具有约1nm至约500nm之间的尺寸或直径的颗粒，更优选具有约30nm至约30nm的尺寸 150nm。 此外，根据本发明的经皮释放材料和试剂掺入优选含有更容易穿透角质层至生理活性剂的生物活性剂的聚合物颗粒，从而使生理活性剂流入皮肤，同时 留在真皮层的上层。

    Composition for skin external application containing gallocatechin gallate for moisturizing effect on the skin
    23.
    发明申请
    Composition for skin external application containing gallocatechin gallate for moisturizing effect on the skin 有权
    用于皮肤外用的组合物，含有gallocatechin没食子酸酯，用于保湿对皮肤的作用

    公开(公告)号：US20120010226A1

    公开(公告)日：2012-01-12

    申请号：US13067719

    申请日：2011-06-22

    申请人： Hyun Shin ,  Jeong Ki Kim ,  Su Nam Kim ,  Sang Min Lee ,  Byeong Gon Lee ,  Ih Seop Chang

    发明人： Hyun Shin ,  Jeong Ki Kim ,  Su Nam Kim ,  Sang Min Lee ,  Byeong Gon Lee ,  Ih Seop Chang

    IPC分类号： A61K8/49 ,  A61Q19/00

    CPC分类号： A61Q19/007 ,  A61K8/498

    摘要： The present invention relates to a composition for external skin application having a skin-moisturizing effect, which comprises gallocatechin gallate as an active ingredient. More particularly, the composition for external skin application comprises gallocatechin gallate as an active ingredient to activate peroxisome proliferator activated receptor isoform alpha (PPAR-α), to stimulate expression of filaggrin and involucrin that are skin-moisturizing factors, and thus to provide excellent anti-drying and skin-moisturizing effects. More particularly, the composition for external skin application may further comprise theobromine and quercetin in addition to gallocatechin gallate to maximize such effects.

    摘要翻译： 本发明涉及具有皮肤保湿作用的外用皮肤用组合物，其包含没食子儿茶素没食子酸镓作为活性成分。 更具体地说，外用皮肤用组合物包含游泳素没食子酸酯作为活性成分，活化过氧化物酶体增殖物激活受体亚型α（PPAR-α），刺激作为皮肤保湿因子的丝聚蛋白和外皮蛋白的表达， 干燥和皮肤保湿效果。 更具体地，用于外用皮肤施用的组合物可以进一步包含可待因和槲皮素，除了没食子儿茶素没食子酸酯以使这种效果最大化。

    Sesamol derivatives or their salts, the process for preparing the same, and the skin external composition containing the same
    24.
    发明授权
    Sesamol derivatives or their salts, the process for preparing the same, and the skin external composition containing the same 有权
    芝麻酚衍生物或其盐，其制备方法以及含有它们的皮肤外用组合物

    公开(公告)号：US07943599B2

    公开(公告)日：2011-05-17

    申请号：US11921180

    申请日：2006-05-29

    申请人： Jae Won You ,  Ho Sik Rho ,  Duck Hee Kim ,  Ih Seop Chang ,  Ok Sub Lee

    发明人： Jae Won You ,  Ho Sik Rho ,  Duck Hee Kim ,  Ih Seop Chang ,  Ok Sub Lee

    IPC分类号： A61K31/66 ,  C07F9/12

    CPC分类号： A61K8/55 ,  A61K2800/522 ,  A61Q19/08 ,  C07F9/65517

    摘要： The present invention relates to a sesamol derivative or its salt, and a skin external composition containing the same. More particularly, the invention relates to a sesamol derivative or its salt, which consists of sesamol and 3-aminopropane phosphoric acid, linked with each other by a phosphoric acid diester bond, and can be degraded into sesamol and 3-aminopropane phosphoric acid by enzymes present on the skin so as to simultaneously show the physiological activities of sesamol and 3-aminopropane phosphoric acid, as well as a preparation method thereof and a skin external composition containing the same.

    摘要翻译： 本发明涉及一种芝麻酚衍生物或其盐，以及包含其的皮肤外用组合物。 更具体地，本发明涉及由芝麻酚和3-氨基丙烷磷酸组成的芝麻酚衍生物或其盐，其通过磷酸二酯键彼此连接，并且可以通过酶降解成芝麻酚和3-氨基丙烷磷酸 存在于皮肤上，以同时显示西沙莫酚和3-氨基丙烷磷酸的生理活性，以及​​其制备方法和含有它们的皮肤外用组合物。