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    Aloe Vera Extract, Method of Producing Aloe Vera Extract, and Hyperglycemia Improving Agent
    22.
    发明申请
    Aloe Vera Extract, Method of Producing Aloe Vera Extract, and Hyperglycemia Improving Agent 审中-公开
    芦荟提取物，芦荟提取物的制备方法和高血糖症改善剂

    公开(公告)号：US20090004307A1

    公开(公告)日：2009-01-01

    申请号：US11815428

    申请日：2006-11-20

    申请人： Miyuki Tanaka ,  Muneo Yamada

    发明人： Miyuki Tanaka ,  Muneo Yamada

    IPC分类号： A61K36/886 ,  A61K31/575 ,  A61P3/10

    CPC分类号： A61K31/58 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/575 ,  A61K36/886 ,  A23V2250/2102 ,  A23V2200/326

    摘要： The present invention provides: an Aloe vera extract that can be safely ingested, can be used as a material of food for preventing lifestyle diseases, contains an extremely low level of an anthraquinone (anthraquinone-based compound), and can be added to foods; and a method of producing the Aloe vera extract. A supercritical fluid extraction method can produce an Aloe vera extract containing a mixture that consists of a cyclolanostane compound and a lophenol compound in an amount of 1.0% by mass or more and having the following properties (1) and/or (2): (1) the mass mixing ratio of the cyclolanostane compound and lophenol compound is as follows: cyclolanostane compound: lophenol compound=6.3:2.7 to 5.1:4.9; and/or (2) the content of an anthraquinone-based compound is 0.001% by mass or less.

    摘要翻译： 本发明提供：可以安全摄取的芦荟提取物，可以用作防止生活方式疾病的食品的材料，含有极低水平的蒽醌（蒽醌类化合物），可以添加到食品中; 以及生产芦荟提取物的方法。 超临界流体萃取法可以生产含有1.0质量％以上的环烷基苯化合物和苯酚化合物的混合物的芦荟提取物，具有以下性质（1）和/或（2）：（ 1）环氨基苯烷化合物和苯酚化合物的质量混合比如下：环丁烷化合物：苯酚化合物= 6.3:2.7〜5.1:4.9; 和/或（2）基于蒽醌的化合物的含量为0.001质量％以下。

    Gene useful for diagnosis and treatment of aplasia of corpus callosum and aspermatogenesis and use thereof
    24.
    发明授权
    Gene useful for diagnosis and treatment of aplasia of corpus callosum and aspermatogenesis and use thereof 失效
    用于诊断和治疗胼of体发育不全的基因和不典型生成及其用途

    公开(公告)号：US07081338B2

    公开(公告)日：2006-07-25

    申请号：US10314395

    申请日：2002-12-06

    申请人： Shinya Suzu ,  Hiroaki Hageshita ,  Kouji Nomaguchi ,  Muneo Yamada ,  Hirotoshi Hayasawa

    发明人： Shinya Suzu ,  Hiroaki Hageshita ,  Kouji Nomaguchi ,  Muneo Yamada ,  Hirotoshi Hayasawa

    IPC分类号： C12Q1/68 ,  C12P19/34

    CPC分类号： C07K14/47 ,  A61K38/00

    摘要： Aplasia of the corpus callosum or aspermatogenesis is diagnosed by investigating existence or expression of the BT-IgSF gene with use of a primer for PCR or probe for hybridization comprising a DNA coding for a novel cell adhesion molecule (BT-IgSF) defined in the following (A) or (B) or a partial sequence thereof: (A) a protein comprising the amino acid sequence of the amino acid numbers 1 to 409 of SEQ ID NO: 2; (B) a protein comprising an amino acid sequence of the amino acid numbers 1 to 409 of SEQ ID NO: 2 including substitution, deletion, insertion or addition of one or several amino acids and having a function as a cell adhesion molecule.

    摘要翻译： 通过使用PCR引物或用于杂交的探针研究BT-IgSF基因的存在或表达来诊断胼the体或异常生殖的发生，包括编码下述定义的新型细胞粘附分子（BT-IgSF）的DNA （A）或（B）或其部分序列：（A）包含SEQ ID NO：2的氨基酸编号1至409的氨基酸序列的蛋白质; （B）包含SEQ ID NO：2的氨基酸编号1至409的氨基酸序列的蛋白质，包括一个或几个氨基酸的取代，缺失，插入或添加并具有作为细胞粘附分子的功能。