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    Respiration monitoring for heart failure using implantable device
    22.
    发明授权
    Respiration monitoring for heart failure using implantable device 失效
    使用可植入装置进行心力衰竭呼吸监测

    公开(公告)号：US08551010B2

    公开(公告)日：2013-10-08

    申请号：US13553098

    申请日：2012-07-19

    申请人： Yachuan Pu ,  Kent Lee ,  Jonathan Kwok ,  Quan Ni

    发明人： Yachuan Pu ,  Kent Lee ,  Jonathan Kwok ,  Quan Ni

    IPC分类号： A61B5/08

    CPC分类号： A61B5/0816 ,  A61B5/0031 ,  A61B5/0452 ,  A61B5/4818 ,  A61N1/3627 ,  A61N1/36521

    摘要： An implantable respiration monitor can be used to detect disordered breathing or periodic breathing events that can be categorized, such as according to one or more of sleep, exercise, and resting awake states. The categorized frequency of such events can be compared to independently specifiable thresholds, such as to trigger an alert or responsive therapy, or to display one or more trends. The information can also be combined with detection of one or more other congestive heart failure (CHF) symptoms to generate a CHF status indicator or to trigger an alarm or responsive therapy or to display one or more trends. The alert can notify the patient or a caregiver, such as via remote monitoring. The sleep state information can be further categorized according to central sleep apnea (CSA) or obstructive sleep apnea (OSA) events.

    摘要翻译： 可植入式呼吸监测器可用于检测可分类的无序呼吸或定期呼吸事件，例如根据睡眠，运动和休眠状态中的一种或多种。 这些事件的分类频率可以与独立指定的阈值进行比较，例如触发警报或响应治疗，或显示一个或多个趋势。 该信息还可以与一种或多种其他充血性心力衰竭（CHF）症状的检测相结合，以产生CHF状态指示器或触发警报或反应性治疗或显示一种或多种趋势。 该警报可以通过远程监视来通知病人或看护者。 睡眠状态信息可以根据中枢性睡眠呼吸暂停（CSA）或阻塞性睡眠呼吸暂停（OSA）事件进一步分类。

    RESPIRATION MONITORING FOR HEART FAILURE USING IMPLANTABLE DEVICE
    25.
    发明申请
    RESPIRATION MONITORING FOR HEART FAILURE USING IMPLANTABLE DEVICE 有权
    使用可移植设备进行心脏衰竭的呼吸监测

    公开(公告)号：US20080039730A1

    公开(公告)日：2008-02-14

    申请号：US11463076

    申请日：2006-08-08

    申请人： Yachuan Pu ,  Kent Lee ,  Jonathan Kwok ,  Quan Ni

    发明人： Yachuan Pu ,  Kent Lee ,  Jonathan Kwok ,  Quan Ni

    IPC分类号： A61B5/02 ,  A61B5/08

    CPC分类号： A61B5/0816 ,  A61B5/0031 ,  A61B5/0452 ,  A61B5/4818 ,  A61N1/3627 ,  A61N1/36521

    摘要： An implantable respiration monitor can be used to detect disordered breathing or periodic breathing events that can be categorized, such as according to one or more of sleep, exercise, and resting awake states. The categorized frequency of such events can be compared to independently specifiable thresholds, such as to trigger an alert or responsive therapy, or to display one or more trends. The information can also be combined with detection of one or more other congestive heart failure (CHF) symptoms to generate a CHF status indicator or to trigger an alarm or responsive therapy or to display one or more trends. The alert can notify the patient or a caregiver, such as via remote monitoring. The sleep state information can be further categorized according to central sleep apnea (CSA) or obstructive sleep apnea (OSA) events.

    摘要翻译： 可植入式呼吸监测器可用于检测可分类的无序呼吸或定期呼吸事件，例如根据睡眠，运动和休眠状态中的一种或多种。 这些事件的分类频率可以与独立指定的阈值进行比较，例如触发警报或响应治疗，或显示一个或多个趋势。 该信息还可以与一种或多种其他充血性心力衰竭（CHF）症状的检测相结合，以产生CHF状态指示器或触发警报或反应性治疗或显示一种或多种趋势。 该警报可以通过远程监视来通知病人或看护者。 睡眠状态信息可以根据中枢性睡眠呼吸暂停（CSA）或阻塞性睡眠呼吸暂停（OSA）事件进一步分类。

    Respiration monitoring for heart failure using implantable device
    27.
    发明授权
    Respiration monitoring for heart failure using implantable device 有权
    使用可植入装置进行心力衰竭呼吸监测

    公开(公告)号：US08226570B2

    公开(公告)日：2012-07-24

    申请号：US11463076

    申请日：2006-08-08

    申请人： Yachuan Pu ,  Kent Lee ,  Jonathan Kwok ,  Quan Ni

    发明人： Yachuan Pu ,  Kent Lee ,  Jonathan Kwok ,  Quan Ni

    IPC分类号： A61B5/08

    CPC分类号： A61B5/0816 ,  A61B5/0031 ,  A61B5/0452 ,  A61B5/4818 ,  A61N1/3627 ,  A61N1/36521

    摘要： An implantable respiration monitor can be used to detect disordered breathing or periodic breathing events that can be categorized, such as according to one or more of sleep, exercise, and resting awake states. The categorized frequency of such events can be compared to independently specifiable thresholds, such as to trigger an alert or responsive therapy, or to display one or more trends. The information can also be combined with detection of one or more other congestive heart failure (CHF) symptoms to generate a CHF status indicator or to trigger an alarm or responsive therapy or to display one or more trends. The alert can notify the patient or a caregiver, such as via remote monitoring. The sleep state information can be further categorized according to central sleep apnea (CSA) or obstructive sleep apnea (OSA) events.

    摘要翻译： 可植入式呼吸监测器可用于检测可分类的无序呼吸或定期呼吸事件，例如根据睡眠，运动和休眠状态中的一种或多种。 这些事件的分类频率可以与独立指定的阈值进行比较，例如触发警报或响应治疗，或显示一个或多个趋势。 该信息还可以与一种或多种其他充血性心力衰竭（CHF）症状的检测相结合，以产生CHF状态指示器或触发警报或反应性治疗或显示一种或多种趋势。 该警报可以通过远程监视来通知病人或看护者。 睡眠状态信息可以根据中枢性睡眠呼吸暂停（CSA）或阻塞性睡眠呼吸暂停（OSA）事件进一步分类。

    Periodic Disordered Breathing Detection
    28.
    发明申请
    Periodic Disordered Breathing Detection 审中-公开
    定期无序呼吸检测

    公开(公告)号：US20110040201A1

    公开(公告)日：2011-02-17

    申请号：US12911233

    申请日：2010-10-25

    申请人： Yanchuan Pu ,  Kent Lee ,  Jonathan Kwok ,  Zheng Lin

    发明人： Yanchuan Pu ,  Kent Lee ,  Jonathan Kwok ,  Zheng Lin

    IPC分类号： A61B5/08

    CPC分类号： A61B5/0816 ,  A61B5/4818 ,  A61N1/3601

    摘要： Systems and methods are directed to evaluating breathing disorders, such as periodic disordered breathing. A signal representative of patient respiration is developed, typically patient-internally. An envelope of the signal is provided. Periodicity of the envelope is detected, and presence and severity of periodic disordered breathing is determined based on the periodicity of the envelope.

    摘要翻译： 系统和方法旨在评估呼吸障碍，例如周期性无序呼吸。 开发代表患者呼吸的信号，通常是患者内部的。 提供信号的包络。 检测到信封的周期，并根据信封的周期确定定期无序呼吸的存在和严重性。

    Thoracic or intracardiac impedance detection with automatic vector selection
    29.
    发明授权
    Thoracic or intracardiac impedance detection with automatic vector selection 有权
    胸部或心内阻抗检测与自动矢量选择

    公开(公告)号：US07630763B2

    公开(公告)日：2009-12-08

    申请号：US11110418

    申请日：2005-04-20

    申请人： Jonathan Kwok ,  Kent Lee ,  Jesse W. Hartley ,  Jeffrey E. Stahmann ,  Yinghong Yu ,  Jiang Ding

    发明人： Jonathan Kwok ,  Kent Lee ,  Jesse W. Hartley ,  Jeffrey E. Stahmann ,  Yinghong Yu ,  Jiang Ding

    IPC分类号： A61B5/053 ,  A61B5/0295

    CPC分类号： A61B5/0205 ,  A61B5/053 ,  A61B5/0538 ,  A61N1/36185 ,  A61N1/36521 ,  A61N1/3686

    摘要： This document discusses, among other things, a cardiac function management device or other implantable medical device that includes a test mode and a diagnostic mode. During a test mode, the device cycles through various electrode configurations for collecting thoracic impedance data. At least one figure of merit is calculated from the impedance data for each such electrode configuration. In one example, only non-arrhythmic beats are used for computing the figure of merit. A particular electrode configuration is automatically selected using the figure of merit. During a diagnostic mode, the device collects impedance data using the selected electrode configuration. In one example, the figure of merit includes a ratio of a cardiac stroke amplitude and a respiration amplitude. Other examples of the figure of merit are also described.

    摘要翻译： 本文件还讨论了包括测试模式和诊断模式的心脏功能管理装置或其它可植入医疗装置。 在测试模式期间，器件循环通过各种电极配置来收集胸部阻抗数据。 从每个这样的电极配置的阻抗数据计算至少一个品质因数。 在一个例子中，仅使用非心律失常节拍来计算品质因数。 使用品质因数自动选择特定的电极配置。 在诊断模式下，设备使用所选择的电极配置收集阻抗数据。 在一个示例中，品质因数包括心搏幅度和呼吸振幅的比值。 还描述了品质因数的其它实例。

    THORACIC OR INTRACARDIAC IMPEDANCE DETECTION WITH AUTOMATIC VECTOR SELECTION
    30.
    发明申请
    THORACIC OR INTRACARDIAC IMPEDANCE DETECTION WITH AUTOMATIC VECTOR SELECTION 有权
    用自动矢量选择进行THORACIC或INTRACARDIAC阻抗检测

    公开(公告)号：US20110301471A1

    公开(公告)日：2011-12-08

    申请号：US13185580

    申请日：2011-07-19

    申请人： Jonathan Kwok ,  Kent Lee ,  Jesse W. Hartley ,  Jeffrey E. Stahmann ,  Yinghong Yu ,  Jiang Ding

    发明人： Jonathan Kwok ,  Kent Lee ,  Jesse W. Hartley ,  Jeffrey E. Stahmann ,  Yinghong Yu ,  Jiang Ding

    IPC分类号： A61B5/0205 ,  A61B5/02

    CPC分类号： A61B5/0205 ,  A61B5/053 ,  A61B5/0538 ,  A61N1/36185 ,  A61N1/36521 ,  A61N1/3686

    摘要： Vector selection is automatically achieved via a thoracic or intracardiac impedance signal collected in a cardiac function management device or other implantable medical device that includes a test mode and a diagnostic mode. During a test mode, the device cycles through various electrode configurations for collecting thoracic impedance data. At least one figure of merit is calculated from the impedance data for each such electrode configuration. In one example, only non-arrhythmic beats are used for computing the figure of merit. A particular electrode configuration is automatically selected using the figure of merit. During a diagnostic mode, the device collects impedance data using the selected electrode configuration. In one example, the figure of merit includes a ratio of a cardiac stroke amplitude and a respiration amplitude. Other examples of the figure of merit are also described.

    摘要翻译： 矢量选择通过收集在包括测试模式和诊断模式的心脏功能管理装置或其他可植入医疗装置中的胸部或心内阻抗信号自动实现。 在测试模式期间，器件循环通过各种电极配置来收集胸部阻抗数据。 从每个这样的电极配置的阻抗数据计算至少一个品质因数。 在一个例子中，仅使用非心律失常节拍来计算品质因数。 使用品质因数自动选择特定的电极配置。 在诊断模式下，设备使用所选择的电极配置收集阻抗数据。 在一个示例中，品质因数包括心搏幅度和呼吸振幅的比值。 还描述了品质因数的其它实例。