公开(公告)号：US20230233757A1

公开(公告)日：2023-07-27

申请号：US18157394

申请日：2023-01-20

Applicant: INSULET CORPORATION

Inventor： David NAZZARO

IPC: A61M5/142 ,  A61M39/12

CPC classification number: A61M5/14244 ,  A61M39/12 ,  A61M5/16804

Abstract: Fluid delivery devices with passive or pressure-based control valves are described. For example, a fluid delivery device may include a fluid path, a pressure source fluidically coupled to a fluid source storing a fluid, and a pressure-based control valve arranged in the fluid path and configured to move in an opening direction in response to a fluid delivery pressure applied by the pressure source in an upstream portion of the fluid path against the pressure-based control valve, in which the pressure control valve is in an open configuration responsive to the fluid delivery pressure being equal to or greater than a cracking pressure. In some embodiments, the pressure-based control valve may be or may include a bourdon tube. Other embodiments are described.

公开(公告)号：US20220203022A1

公开(公告)日：2022-06-30

申请号：US17553699

申请日：2021-12-16

Applicant: Insulet Corporation

Inventor： David NAZZARO ,  John D'ARCO ,  Nicholas CONTE ,  Kepei SUN

IPC: A61M5/142 ,  G16H40/67 ,  G16H20/17

Abstract: An on-body drug delivery device may have one or more antennas secured outside a housing of the on-body drug delivery device for facilitating wireless communications. The one or more antennas may be secured to an adhesive pad that adheres the on-body drug delivery device to a user. Alternatively, the one or more antennas may be secured to a portion of the housing for the on-body drug delivery device. In such instances, the one or more antennas may pass through one or more holes in the housing to facilitate an electrical connection with a component, like a wireless communications transceiver, inside the housing. Alternatively, wireless communications with the one or more antennas and the component may be used.

公开(公告)号：US20210249115A1

公开(公告)日：2021-08-12

申请号：US16787223

申请日：2020-02-11

Applicant: INSULET CORPORATION

Inventor： David NAZZARO ,  Steven CARDINALI ,  Nicholas CONTE ,  Daniel ALLIS ,  Jason O'CONNOR ,  Joon Bok LEE ,  Ashutosh ZADE ,  Timothy HENNING ,  Thomas METZMAKER ,  Ian MCLAUGHLIN

IPC: G16H20/60 ,  G16H20/17

Abstract: Disclosed are examples of a device, a system, methods and computer-readable medium products operable to implement functionality to determine and respond to a purpose of a meal. An algorithm or application may receive data that may include data related to a meal purpose from data sources and determine whether any of the data received from the plurality of data sources was received from a direct data source or an indirect data source. The data may be evaluated to determine a purpose of the meal. Based on the results of the evaluation, instructions may be generated to provide an appropriate response based on the determined purpose of the meal. The generated instructions to provide the appropriate response based on the determined purpose of the meal may be output.

公开(公告)号：US20200282131A1

公开(公告)日：2020-09-10

申请号：US16884832

申请日：2020-05-27

Applicant: Insulet Corporation

Inventor： David NAZZARO

IPC: A61M5/145 ,  A61M5/158 ,  A61M5/14 ,  A61M5/142

Abstract: A wearable drug delivery device that can deliver high volumes of liquid drugs stored in one or more corresponding containers to a patient is provided. The wearable drug delivery device can include first and second containers to store first and second liquid drugs, respectively. A first set of energy transfer spheres can be coupled to a first spring and a first plunger positioned within the first container. A second set of energy transfer spheres can be coupled to a second spring and a second plunger positioned within the second container. The first spring can expand to advance the first set of energy transfer spheres and the first plunger to expel the first liquid drug for delivery to the patient. The second spring can expand to advance the second set of energy transfer spheres and the second plunger to expel the second liquid drug for delivery to the patient.

公开(公告)号：US20200254179A1

公开(公告)日：2020-08-13

申请号：US16859544

申请日：2020-04-27

Applicant: INSULET CORPORATION

Inventor： David NAZZARO ,  Maureen MCCAFFREY ,  Robert F. RIOUX ,  Michael Philip GRAFFEO ,  Ian MCLAUGHLIN ,  Nicholas JANSKY ,  Sam ROSENBLUM ,  David CLARE ,  Robert D. SCHAEFER ,  Daniel P. ALLIS ,  Bryan DILLON ,  Steven BARLETTA ,  Bryan CHOATE ,  Raymond DOBRY ,  John LEFAVOUR

IPC: A61M5/178

Abstract: Systems, components, and methods are disclosed for withdrawing drug from a liquid drug container and transferring drug to a medical device. One or more components may have keying features so that only the correct liquid drug container and medical device are accessed, making sure the medical device is filled with the correct drug. A syringe needle hub may have keying features corresponding to keying features on a cap on the liquid drug container and on the medical device. An alignment device facilitates easy-to-operate filling of a medical device. The alignment device aligns a liquid drug container over a fill port of the medical device and can include components for moving the liquid drug container into engagement with the medical device and for automatically initiating drug transfer to the medical device. A retractable skirt or needle cover protects the needle and is unlocked only when the skirt or needle cover is close to or touching the medical device.

公开(公告)号：US20200179608A1

公开(公告)日：2020-06-11

申请号：US16794689

申请日：2020-02-19

Applicant: Insulet Corporation

Inventor： Maureen MCCAFFREY ,  David NAZZARO ,  Ian MCLAUGHLIN ,  Simon KOZIN

IPC: A61M5/28 ,  A61M5/24 ,  A61M5/34 ,  A61M5/32 ,  A61M5/315 ,  A61M5/142

Abstract: Drug delivery systems with reduced hold-up volumes are provided. The drug delivery systems include a cartridge configured to hold a liquid drug. A cartridge stopper is positioned in a first portion of the cartridge. A needle guide component is positioned within the cartridge stopper. A needle is positioned within a central opening of the needle guide. A plunger is positioned in a second portion of the cartridge. The plunger includes a fluid path pocket facing and aligned with the central opening of the needle guide component. The plunger is driven toward the cartridge stopper to expel the liquid drug from the cartridge through the needle. An end of the needle can be positioned within the fluid path pocket when the plunger is pushed against the cartridge stopper, ensuring that only a small volume of the liquid drug remains in the cartridge when delivery of the liquid drug is completed.

公开(公告)号：US20190038835A1

公开(公告)日：2019-02-07

申请号：US16049388

申请日：2018-07-30

Applicant: Insulet Corporation

Inventor： David NAZZARO ,  Ian MCLAUGHLIN ,  Daniel ALLIS ,  Jason O'CONNOR

IPC: A61M5/168 ,  A61M5/28 ,  A61M5/32 ,  A61M5/315

Abstract: A fluid flow regulator of a fluid delivery system that can adjust a flow rate of a liquid drug dispensed from a liquid drug container to a user is provided. The fluid flow regulator can be coupled to an end of the liquid drug container. The fluid flow regulator can include a compliance plate and a flow channel selector plate having a fluid flow channel. The flow channel selector plate can be rotated relative to the compliance plate and the liquid drug container to expose a selected portion of the fluid flow channel to openings in the compliance plate that are in fluid communication with the liquid drug stored in the liquid drug container. The selected portion of the fluid flow channel can correspond to a corresponding flow resistance of the liquid drug through the fluid flow channel, thereby regulating the flow of the liquid drug to the user.

公开(公告)号：US20180043089A1

公开(公告)日：2018-02-15

申请号：US15676289

申请日：2017-08-14

Applicant: Insulet Corporation

Inventor： David NAZZARO

IPC: A61M5/145

CPC classification number: A61M5/31568 ,  A61M5/14248 ,  A61M5/1452 ,  A61M5/1454 ,  A61M5/2033 ,  A61M5/3155 ,  A61M2005/14252 ,  A61M2005/14533 ,  A61M2005/2073 ,  A61M2005/31518 ,  A61M2202/0468 ,  A61M2205/3306 ,  A61M2205/3317 ,  A61M2205/3379 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/584

Abstract: Variable fill drug delivery devices for delivering a therapeutic agent to a patient are provided. A variable fill drug delivery device includes a drug container to store a variable amount (or user-selectable amount) of a therapeutic agent. A plunger of the variable fill drug delivery device is positioned in the drug container. An infusion engine of the variable fill device is coupled to the plunger. The infusion engine retains the plunger prior to activation of the variable fill drug delivery device and releases the plunger after activation of the variable fill drug delivery device. After activation, the infusion engine drives the plunger from a first position within the drug container to a second position within the drug container to expel the variable amount of the therapeutic agent from the drug container for delivery to a patient.

公开(公告)号：US20240269379A1

公开(公告)日：2024-08-15

申请号：US18643990

申请日：2024-04-23

Applicant: INSULET CORPORATION

Inventor： Jason O'CONNOR ,  Ian MCLAUGHLIN ,  Daniel ALLIS ,  David NAZZARO

IPC: A61M5/145 ,  A61M5/142 ,  A61M5/158 ,  A61M5/162 ,  A61M5/168

CPC classification number: A61M5/14566 ,  A61M5/14248 ,  A61M5/1582 ,  A61M5/162 ,  A61M5/16881 ,  A61M2005/14252 ,  A61M2205/3379 ,  A61M2205/583

Abstract: Disclosed are examples for a system for drug delivery and components thereof. The system may include an on-body pump device and a secondary unit. The on-body pump device may include a reservoir and a fluid pathway. The reservoir may be configured to hold a liquid drug. The secondary unit may be removably coupled to the on-body pump device. The secondary unit may be configured to receive a prefilled cartridge containing a liquid drug, expel the liquid drug from the prefilled cartridge, and deliver the liquid drug to the reservoir of the on-body pump device via the fluid pathway. Examples of variations to the secondary unit are also disclosed.

公开(公告)号：US20240181156A1

公开(公告)日：2024-06-06

申请号：US18523130

申请日：2023-11-29

Applicant: INSULET CORPORATION

Inventor： James CAUSEY ,  David NAZZARO

IPC: A61M5/158

CPC classification number: A61M5/158 ,  A61M2005/1585

Abstract: Disclosed are systems, processes and techniques implementable in and by medical devices that utilize the subcutaneous region of the skin. In the disclosed examples, an insertion mechanism is provided that inserts a cannula or sensing element into the subcutaneous region of the skin a first distance and retracts the inserted cannula or sensing element a second distance that is smaller than the first distance to create a cavity below the inserted cannula or sensing element. The retracted cannula or sensing element remains inserted in the subcutaneous region of the skin. The cavity provides an area for the effects of a wound response to occur and thereby mitigates possibility of occlusion and/or encapsulation of the inserted cannula or sensing element.