摘要:
A system and method for replacing degenerated spinal disks in accordance with the present invention can substitute for interbody fusion techniques by replacing degenerated spinal disks with artificial spinal disks. In one embodiment, the system can comprise one or more artificial spinal disks, each comprising an upper and lower housing, a first spacer and a second spacer partially enclosed by a cavity formed by the housings, and a shaft with a spring positioned between the first spacer and the second spacer such that the spacers are urged apart.
摘要:
The present invention relates to methods and compositions for the diagnosis and therapy of prostate cancer which utilize isolated polynucleotides corresponding to the human SGP28 gene, proteins encoded by the SGP28 gene and fragments thereof, and antibodies capable of specifically recognizing and binding to SGP28 proteins.
摘要:
A tool for securing a connector on a conductor using an explosive charge includes a first tool member, a second tool member, a drive member, a lock member and a limiting member. The second tool member is movably mounted on the first tool member. A breech chamber is defined in at least one of the first and second tool members. The breech chamber is adapted to receive the explosive charge. A breech opening is defined in at least one of the first and second tool members. The breech opening communicates with the breech chamber. The tool is adapted to forcibly move the drive member responsive to an explosion of the explosive charge in the breech chamber. The second tool member is movable between a closed position, wherein the breech opening is closed, and an open position, wherein the breech opening is open to allow loading and unloading of the explosive charge into and from the breech chamber, by moving the second tool member relative to the first tool member. The lock member is selectively movable between a locked position, wherein the lock member prevents the second tool member from moving relative to the first tool member from the closed position to the open position, and an unlocked position, wherein the lock member permits the second tool member to move relative to the first tool member from the closed position to the open position. The limiting member is selectively movable between a first position, wherein the limiting member prevents movement of the lock member from the locked position to the unlocked position, and a second position, wherein the limiting member permits the lock member to move from the locked position to the unlocked position.
摘要:
An intervertebral implant has a fusion body with at least one keel that anchors the implant into cancellous bone of at least one vertebral body. A method for implantation includes lateral implantation of the implant.
摘要:
An implant for positioning between the spinous processes of cervical vertebrae include first and second wings for lateral positioning and a spacer located between the adjacent spinous processes. The implant can be positioned using minimally invasive procedures without modifying the bone or severing ligaments. The implant is shaped in accordance with the anatomy of the spine.
摘要:
The present invention is directed to a device that can be placed between two vertebrae. The implant is characterized by having a first plate and a second plate with a crossbar therebetween. The crossbar fits within cavities on each of the first and second plates and allows for pivotal or rotational motion and also for twisting motion.
摘要:
A transverse wedge connector system for forming an electrical connection with first and second elongate electrical conductors includes an electrically conductive first connector member, an electrically conductive second connector member, an insert member, and a clamping mechanism. The first connector member includes a first body having a first channel portion and a first abutment portion. The first channel portion defines a first channel to receive the first conductor. The second connector member includes a second body having a second channel portion and a second abutment portion. The second channel portion defines a second channel to receive the second conductor. The insert member is configured to be selectively mounted in the first channel and defining an insert member channel to receive the first conductor when the insert member is mounted in the first channel The clamping mechanism is selectively operable to displace the first and second connector members relative to one another from an open position to a closed position to clamp the first conductor between the first channel portion and the second abutment surface, and to clamp the second conductor between the second channel portion and the first abutment portion to thereby form a connection.
摘要:
A novel gene (designated PHOR-1) that is highly over-expressed in prostate and other cancers and its encoded protein are described. PHOR-1 is a G protein-coupled receptor with homology to receptors involved in olfaction. PHOR-1 in normal human tissues is restricted to prostate, and this gene is highly over-expressed in prostate cancer as well as in cancers of the kidney, uterus, cervix, stomach and rectum. Consequently, PHOR-1 provides a diagnostic and/or therapeutic target for prostate cancer.
摘要:
An implant is used to distract and maintain the distraction of spinous processes of adjacent vertebrae of the spine. The implant can be secured to a spine stabilization system.
摘要:
A tool for securing a connector on a conductor using an explosive charge includes a first tool member, a second tool member, a drive member, a lock member and a limiting member. The second tool member is movably mounted on the first tool member. A breech chamber is defined in at least one of the first and second tool members. The breech chamber is adapted to receive the explosive charge. A breech opening is defined in at least one of the first and second tool members. The breech opening communicates with the breech chamber. The tool is adapted to forcibly move the drive member responsive to an explosion of the explosive charge in the breech chamber. The second tool member is movable between a closed position, wherein the breech opening is closed, and an open position, wherein the breech opening is open to allow loading and unloading of the explosive charge into and from the breech chamber, by moving the second tool member relative to the first tool member. The lock member is selectively movable between a locked position, wherein the lock member prevents the second tool member from moving relative to the first tool member from the closed position to the open position, and an unlocked position, wherein the lock member permits the second tool member to move relative to the first tool member from the closed position to the open position. The limiting member is selectively movable between a first position, wherein the limiting member prevents movement of the lock member from the locked position to the unlocked position, and a second position, wherein the limiting member permits the lock member to move from the locked position to the unlocked position.