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46 条记录 (耗时 0.069 秒)

    Medical device having a rotatable shaft
    24.
    发明授权
    Medical device having a rotatable shaft 有权
    具有旋转轴的医疗装置

    公开(公告)号：US08292940B2

    公开(公告)日：2012-10-23

    申请号：US12369711

    申请日：2009-02-11

    申请人： Richard Olson

    发明人： Richard Olson

    IPC分类号： A61F2/06

    CPC分类号： A61M25/0043 ,  A61F2/856 ,  A61F2/954 ,  A61F2/958 ,  A61F2210/0076 ,  A61M25/0158 ,  A61M2025/0058 ,  A61M2025/1045

    摘要： The invention provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device includes a first elongated member having a proximal end, a distal end, and a lumen extending therebetween and a second elongated member having a proximal end, a distal end, and a lumen extending therebetween. The proximal end of the second elongated member may be disposed adjacent to the distal end of the first elongated member forming an actuatable junction. In some cases, the actuatable junction may be actuatable between a first state and a second state. When in the first state, the first elongated member may be rotatable relative to the second elongated member and, when in the second state, the first elongated member may be fluidly sealed to the second elongated member.

    摘要翻译： 本发明提供医疗设备的设计，材料，制造方法和替代方案。 示例性医疗装置包括具有近端，远端和在其间延伸的内腔的第一细长构件和具有近端，远端和在其间延伸的内腔的第二细长构件。 第二细长构件的近端可以邻近第一细长构件的远端设置，形成可致动的结。 在一些情况下，可致动接头可以在第一状态和第二状态之间起动。 当处于第一状态时，第一细长构件可以相对于第二细长构件旋转，并且当处于第二状态时，第一细长构件可以流体地密封到第二细长构件。

    Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging
    26.
    发明申请
    Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging 审中-公开
    使用小分子放射性配体发现淀粉样蛋白β肽生产抑制剂和诊断成像

    公开(公告)号：US20050129612A1

    公开(公告)日：2005-06-16

    申请号：US11018331

    申请日：2004-12-21

    申请人： Robert Zaczek ,  Richard Olson ,  Dietmar Seiffert ,  Lorin Thompson

    发明人： Robert Zaczek ,  Richard Olson ,  Dietmar Seiffert ,  Lorin Thompson

    IPC分类号： A61K51/08 ,  A61K51/00

    CPC分类号： A61K51/0468

    摘要： This invention relates to a method of using radiolabelled and/or radiopharmaceutical small molecule inhibitors of beta-amyloid peptide production for the diagnosis of neurological and other disorders involving APP processing and beta-amyloid production. Furthermore, radiolabelled small molecule inhibitors identified by the methods of the present invention would be useful in the diagnosis of neurological disorders, such as Alzheimer's disease, which involve elevated levels of Aβ peptides.

    摘要翻译： 本发明涉及使用放射性标记的和/或放射性药物的β-淀粉样蛋白肽生产的小分子抑制剂用于诊断涉及APP处理和β-淀粉样蛋白生成的神经和其他病症的方法。 此外，通过本发明的方法鉴定的放射性标记的小分子抑制剂可用于诊断涉及升高水平的Aβ肽的神经障碍，例如阿尔茨海默氏病。

    Ear cleaning device with an integral bulbous end
    27.
    发明申请
    Ear cleaning device with an integral bulbous end 有权
    耳朵清洁装置具有整体的球根端

    公开(公告)号：US20050096678A1

    公开(公告)日：2005-05-05

    申请号：US10960204

    申请日：2004-10-07

    申请人： Richard Olson

    发明人： Richard Olson

    IPC分类号： A61F11/00 ,  A61F9/00

    CPC分类号： A61F11/006

    摘要： A disposable ear cleaning device having a one-piece, plastic body with an integral scoop at one end having a bowl portion having a smooth lower surface on the bowl. Openings may be formed in the bottom of the bowl for scraping wax and debris from the ear. The preferred openings are parallel slots. The preferred bowl has rounded, upper edges at the rim for scraping ear wax with the front, distal end at a lower height than a rear end of the bowl which is joined to a handle. The preferred handle may be fluted for gripping and turning the bowl when scraping ear wax. A flexible neck may join the bowl to the handle. A bulbous end of plastic or of cotton may be provided at the end of the device opposite the bowl. The referred cleaning device weighs less than one gram and is inexpensive.

    摘要翻译： 一次性耳朵清洁装置具有一体的塑料体，其一端具有整体的勺子，其具有在碗上具有平滑下表面的碗部分。 可以在碗的底部形成开口，用于刮擦来自耳朵的蜡和碎屑。 优选的开口是平行的槽。 优选的碗在轮缘处具有圆形的上边缘，用于刮擦耳蜡，其前部的远端处于比碗的后端更低的高度，该后端连接到手柄。 当刮耳蜡时，优选的手柄可以是槽纹以用于夹紧和转动碗。 柔性颈部可以将碗连接到手柄。 可以在与碗相对的装置的端部处设置塑料或棉花的球形末端。 所引用的清洁装置重量小于1克并且便宜。