公开(公告)号：US06767450B2

公开(公告)日：2004-07-27

申请号：US09823840

申请日：2001-03-30

申请人： Masaaki Terashima ,  Osamu Seshimoto ,  Yoshikazu Amano

发明人： Masaaki Terashima ,  Osamu Seshimoto ,  Yoshikazu Amano

IPC分类号： G01N27333

CPC分类号： G01N27/333

摘要： A composite ion selective electrode comprising a calcium ion selective electrode member and a hydrogen ion selective electrode member which is characterized in that a calcium ion selective membrane of the calcium ion selective electrode member has a thickness of 5 to 30 &mgr;m, and the hydrogen ion selective membrane of the hydrogen ion selective electrode member contains tri-n-dodecyl-amine and trisethylhexyl trimellitate. Each of the calcium ion selective electrode member and the hydrogen ion selective electrode member can be employed singly.

摘要翻译： 1.一种复合离子选择电极，其包含钙离子选择电极部件和氢离子选择电极部件，其特征在于，所述钙离子选择电极部件的钙离子选择性膜的厚度为5〜30μm，氢离子选择性 氢离子选择电极构件的膜包含三正十二烷基胺和偏苯三酸三乙基己酯。 钙离子选择电极构件和氢离子选择电极构件中的每一个可以单独使用。

公开(公告)号：US06659288B2

公开(公告)日：2003-12-09

申请号：US09858391

申请日：2001-05-16

申请人： Yoshikazu Amano ,  Toshihiro Mori

发明人： Yoshikazu Amano ,  Toshihiro Mori

IPC分类号： B01D3500

CPC分类号： B01D39/2017

摘要： A plasma- or serum-collecting device with simple structure and easy to handle is provided. The device comprises a vacuum blood-drawing tube accommodating a blood-filtering unit, wherein the vacuum tube contains a space above the blood-filtering unit to preserve blood to be filtered and a partition wall under the blood-filtering unit to keep a backspace at reduced pressure, and the blood-filtering unit contains a communicating needle to break the partition wall at the bottom.

摘要翻译： 提供了一种结构简单，易于操作的等离子体或血清采集装置。 所述装置包括容纳血液净化单元的真空吸血管，其中所述真空管包含所述血液过滤单元上方的空间，以保持要过滤的血液和所述血液净化单元下方的分隔壁以保持退格 减压，血液滤过单元含有连通针，以破坏底部的分隔壁。

公开(公告)号：US06531323B1

公开(公告)日：2003-03-11

申请号：US09493574

申请日：2000-01-28

申请人： Hiroshi Shinoki ,  Yoshikazu Amano

发明人： Hiroshi Shinoki ,  Yoshikazu Amano

IPC分类号： G01N33546

CPC分类号： G01N33/54313 ,  G01N33/54393 ,  Y10S435/969 ,  Y10S436/805

摘要： An agglutination assay method for quantitatively determination of an analyte in a liquid sample using particles bearing an anti-analyte. A non-fluid substance which retains the particles while suppressing the diffusion of the particles therein is used as a medium which is to be a place where the agglutination of the particles takes place. Upon analysis, a solation agent is added to the non-fluid substance medium to increase the fluidity of the non-fluid substance, thereby the particles bearing the anti-analyte can diffuse in the medium to cause the agglutination with the analyte. Preferably, the solation agent is added to the non-fluid medium together with the sample. The non-fluid substance medium containing the particle-labeled anti-analyte can be stored with a higher stability in the dry state. A dry analysis element for enabling such analysis method is also provided.

摘要翻译： 用于使用带有抗分析物的颗粒定量测定液体样品中的分析物的凝集测定方法。 使用保持颗粒同时抑制颗粒扩散的非流体物质作为发生颗粒凝集的地方的介质。 分析后，向非流体物质介质中加入溶剂，以增加非流体物质的流动性，从而带有抗分析物的颗粒可以在介质中扩散以引起与分析物的凝集。 优选地，将溶剂与样品一起添加到非流体介质中。 含有颗粒标记的抗分析物的非流体物质介质可以在干燥状态下以更高的稳定性储存。 还提供了用于实现这种分析方法的干燥分析元件。

公开(公告)号：US06255061B1

公开(公告)日：2001-07-03

申请号：US09464613

申请日：1999-12-15

申请人： Toshihiro Mori ,  Takaki Arai ,  Yoshikazu Amano

发明人： Toshihiro Mori ,  Takaki Arai ,  Yoshikazu Amano

IPC分类号： C12Q154

CPC分类号： G01N33/525 ,  C12Q1/26 ,  C12Q1/28 ,  Y10S435/966

摘要： An analytical element for quantitative analysis of glucose, cholesterol, or lactic acid in whole blood, composed of a porous layer which has a void volume of 30 to 80% and containing peroxidase, a leuco dye which gives coloring having an absorption peak in the region of 600 to 700 nm, and an oxidase such as glucose oxidase, cholesterol oxidase, or lactate oxidase, respectively. The porous layer can be placed on a transparent support sheet via an adhesive layer in the form of dots or lines, or a hydrophilic adhesive layer.

摘要翻译： 用于定量分析全血中的葡萄糖，胆固醇或乳酸的分析元件，其由空隙体积为30至80％的多孔层和含有过氧化物酶的无机染料组成，所述无色染料在所述区域中具有吸收峰 分别为600〜700nm，氧化酶如葡萄糖氧化酶，胆固醇氧化酶或乳酸氧化酶。 多孔层可以通过粘合剂层以点或线的形式或亲水性粘合剂层放置在透明支撑片上。

公开(公告)号：US6068989A

公开(公告)日：2000-05-30

申请号：US387117

申请日：1999-08-31

申请人： Hideaki Tanaka ,  Yoshikazu Amano

发明人： Hideaki Tanaka ,  Yoshikazu Amano

IPC分类号： C12Q1/32 ,  C12Q1/527 ,  C12Q1/00 ,  C12Q1/48

CPC分类号： C12Q1/32 ,  C12Q1/527

摘要： This invention provides a reagent composition for the determination of bicarbonate ion capable of measuring in a wide determination range in visible light region which comprises a combined substrate of thioNAD(P)H and NAD(P)H for a coupled enzymes of phosphoenolpyruvate carboxylase and malate dehydrogenase.

摘要翻译： 本发明提供了一种用于测定碳酸氢根离子的试剂组合物，其能够在可见光区域的广泛测定范围内测量，所述可见光区域包含硫代纳（P）H和NAD（P）H的组合底物，用于磷酸烯醇丙酮酸羧化酶和苹果酸的偶联酶 脱氢酶。

公开(公告)号：US5150055A

公开(公告)日：1992-09-22

申请号：US618931

申请日：1990-11-28

申请人： Mitsuyoshi Kimura ,  Yoshikazu Amano

发明人： Mitsuyoshi Kimura ,  Yoshikazu Amano

IPC分类号： G01R33/3875 ,  A61B5/055 ,  G01R33/385 ,  G01R33/387

CPC分类号： G01R33/3852

摘要： A gradient magnetic field coil is excited by coil exciting means, thereby a gradient magnetic field being generated. The gradient magnetic field generates eddy current in an eddy current generating portion, the magnetic field due to this eddy current disturbing the gradient magnetic field. Means for compensating the magnetic field due to the eddy current is disposed, this means having a transmission function representing an inverse of the transmission function of a gradient magnetic field system including the gradient magnetic field coil and the eddy current generating portion.

摘要翻译： 梯形磁场线圈被线圈激励装置激励，从而产生梯度磁场。 梯度磁场在涡流产生部分产生涡电流，由于该涡流扰动了梯度磁场而产生的磁场。 设置用于补偿由于涡电流引起的磁场的装置，这意味着具有表示与包括梯度磁场线圈和涡流产生部分的梯度磁场系统的传输函数相反的传递函数。

公开(公告)号：US20110147430A1

公开(公告)日：2011-06-23

申请号：US12863255

申请日：2008-12-18

申请人： Michihiro Sato ,  Yoshikazu Amano

发明人： Michihiro Sato ,  Yoshikazu Amano

IPC分类号： B65H35/06 ,  B32B7/12

CPC分类号： B65D83/0882 ,  B32B7/06 ,  B32B7/12 ,  B32B27/32 ,  B32B2255/10 ,  B32B2255/26 ,  B32B2255/28 ,  B32B2519/00 ,  Y10T225/222 ,  Y10T225/238 ,  Y10T225/243 ,  Y10T225/246 ,  Y10T428/14 ,  Y10T428/1476

摘要： A wrapping film container, including: an elongated container body for housing therein a rolled self-tacky wrapping film, an opening provided to the container body along a longitudinal direction of the container body for pulling out a portion of the wrapping film therethrough, cutting means for cutting the pulled-out portion of the wrapping film and a film-holding section provided on a front face of the container body for preventing re-winding to an inside of the container, wherein the film-holding section comprises a laminate structure including a pressure-sensitive adhesive layer, a substrate layer, an adhesive layer and a self-tacky film layer, disposed sequentially from the container body side. The film-holding section is efficiently formed on the front face of the container body by using a label for forming film-holding section of a wrapping film container having a laminate structure including a self-tacky film layer, an adhesives layer, a base material layer, a pressure-sensitive adhesive layer and a separator layer, disposed sequentially from one side thereof, and exhibits a stable and consistent film-holding power.

摘要翻译： 一种包装膜容器，包括：用于容纳滚动的自粘包装膜的细长容器主体，沿着容器主体的纵向方向设置到容器主体的开口，用于将一部分包裹膜拉出，切割装置 用于切割包装膜的拉出部分和设置在容器主体前表面上的胶片保持部分，用于防止再卷绕到容器的内部，其中胶片保持部分包括层压结构，其包括 压敏粘合剂层，基材层，粘合剂层和自粘膜层，从容器主体侧依次设置。 通过使用具有层叠结构的包装膜容器的形成用保鲜部的标签，在容器主体的前面有效地形成保持膜，该层压结构包括自粘膜层，粘合层，基材 层，压敏粘合剂层和隔离层，从其一侧依次设置，并且表现出稳定且一致的膜保持力。

公开(公告)号：US20100282811A1

公开(公告)日：2010-11-11

申请号：US12679737

申请日：2008-09-26

申请人： Michihiro Sato ,  Yoshikazu Amano ,  Makoto Unno ,  Shinichi Sekine ,  Kenichi Ishi

发明人： Michihiro Sato ,  Yoshikazu Amano ,  Makoto Unno ,  Shinichi Sekine ,  Kenichi Ishi

IPC分类号： B65H35/06

CPC分类号： B65D83/0841 ,  B26D1/0006 ,  B26D2001/006 ,  B26F3/02 ,  B65D85/672 ,  Y10T225/298

摘要： A cutting edge 24 is divided into a center area 28 including a V-shaped apex portion, a pair of intermediate areas 29 on the outer sides thereof, and a pair of side areas 30 on the farther outer sides thereof. The center area 28 has first teeth with the highest tooth height and second teeth with a smaller tooth height, the first teeth being situated at the apex portion and the second teeth being situated between the first teeth at a prescribed spacing around them as the center. A first straight line connecting the tips of the first teeth, a second straight line connecting the tips of the second teeth and a third straight line connecting the bases of the first teeth and second teeth are parallel, the second straight line being located between the first straight line and third straight line. The tips of the intermediate teeth of the intermediate area 29 are located on the second straight line or between the second straight line and third straight line. The tips of the side teeth of the side area 30 are located on the second straight line or between the first straight line and second straight line.

摘要翻译： 切割刃24被分成包括V形顶点部分，其外侧上的一对中间区域29和更远的外侧上的一对侧面区域30的中心区域28。 中心区域28具有齿高度最高的第一齿和具有较小齿高度的第二齿，第一齿位于顶点处，第二齿以围绕它们的中心以规定间隔位于第一齿之间。 连接第一齿的尖端的第一直线，连接第二齿的末端的第二直线和连接第一齿和第二齿的基部的第三直线是平行的，第二直线位于第一齿之间 直线和第三条直线。 中间区域29的中间齿的尖端位于第二直线上或第二直线和第三直线之间。 侧面区域30的侧齿的尖端位于第二直线上或第一直线与第二直线之间。

公开(公告)号：US07820402B2

公开(公告)日：2010-10-26

申请号：US11230127

申请日：2005-09-19

申请人： Yoshiki Sakaino ,  Hitomi Ito ,  Toshihiro Mori ,  Osamu Seshimoto ,  Toshihisa Ito ,  Yoshikazu Amano

发明人： Yoshiki Sakaino ,  Hitomi Ito ,  Toshihiro Mori ,  Osamu Seshimoto ,  Toshihisa Ito ,  Yoshikazu Amano

IPC分类号： G01N33/53 ,  G01N33/543

CPC分类号： G01N33/54386 ,  G01N2333/924 ,  Y10S435/966 ,  Y10S435/969 ,  Y10S435/97 ,  Y10S436/807 ,  Y10S436/81

摘要： The immunoassay element for quantitatively analyzing an antigen by determining the change in enzymatic activity of an enzyme-labelled antigen or antibody caused by an immunological reaction. The immunoassay element comprises a substrate layer containing a non-diffusible substrate which forms a diffusible material in the presence of the labelling enzyme, and a reagent layer containing a fragmenting enzyme for further fragmenting the diffusible material into a lower molecular weight product. As the non-diffusible substrate, a substrate capable of reacting solely with the labelling enzyme and incapable of reacting the fragmenting enzyme is utilized. When an endo-active glucosidase is used as the labelling enzyme, and an exo-active glucosidase is used the fragmenting enzyme in the reagent layer, the non-diffusible substrate of the substrate layer is preferred to be an endo type selectively reactive substrate, which means a substrate having a reactivity specific to endo-active glucosidase. Highly sensitive assay is realized with high accuracy and high reproducibility and good storage stability.

摘要翻译： 用于通过确定由免疫反应引起的酶标记的抗原或抗体的酶活性的变化来定量分析抗原的免疫测定元件。 免疫测定元件包括含有在标记酶存在下形成可扩散材料的不扩散基底的底物层和含有用于进一步将可扩散材料分解成较低分子量产物的碎裂酶的试剂层。 作为非扩散性底物，使用能够仅与标记酶反应并且不能使片段化酶反应的底物。 当使用内源活性葡糖苷酶作为标记酶，并且使用外源活性葡糖苷酶时，试剂层中的断裂酶，底物层的非扩散性基质优选为内型选择性反应性底物，其中 是指具有对内源性葡糖苷酶特异性的反应性的底物。 高精度，高重现性和良好的储存稳定性实现了高灵敏度测定。

公开(公告)号：US20070244293A1

公开(公告)日：2007-10-18

申请号：US10593230

申请日：2005-03-17

申请人： Hiroyuki Sato ,  Fuminori Kobayashi ,  Yukichika Kawakami ,  Kazuyuki Yamane ,  Yoshikazu Amano ,  Takashi Sato

发明人： Hiroyuki Sato ,  Fuminori Kobayashi ,  Yukichika Kawakami ,  Kazuyuki Yamane ,  Yoshikazu Amano ,  Takashi Sato

IPC分类号： C08G63/08 ,  C08G63/88

CPC分类号： C08G63/90 ,  C08G63/06 ,  C08G63/80

摘要： In the production of an aliphatic polyester by ring-opening polymerization of a cyclic ester, at least a latter period of polymerization is proceeded with by way of solid-phase polymerization, and the resultant aliphatic polyester is subjected to removal of residual cyclic ester. As a result, an aliphatic polyester with a minimized content of residual monomer is obtained.

摘要翻译： 在通过环状酯的开环聚合生产脂肪族聚酯时，至少通过固相聚合进行聚合的后期，并将所得的脂族聚酯除去残留的环状酯。 结果，得到残留单体含量最小的脂肪族聚酯。