摘要:
A compound having GSK-3 inhibiting function. A1 and A3 are a single bond, an aliphatic hydrocarbon group; A2 and A4 are a single bond, CO, COO, CONR, O, OCO, NR, NRCO, NRCOO, etc.; G1 is a single bond, an aliphatic hydrocarbon, aromatic hydrocarbon, heterocyclic; G2 is a hydrogen atom, an aliphatic hydrocarbon, an alicyclic hydrocarbon, an aromatic hydrocarbon, heterocyclic; A5 is a single bond, NR; R2 is H, halogen, an aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; A6 is a single bond, NR, CO, NRCO, NRCONR, CONR, COO, O, etc.; R3 is H, halogen, nitro, saturated aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; and when A6 is CR═CR or C≡C; R3 may be a trimethylsilyl, formyl, acyl, carboxyl, alkoxylcarbonyl, carbamoyl, alkylcarbamoyl or cyano group; and R is H or an aliphatic hydrocarbon group.
摘要翻译:具有GSK-3抑制功能的化合物。 A 1和A 3是单键,脂族烃基; A <2>和A 4是单键,CO,COO,CONR,O,OCO,NR,NRCO,NRCOO等; G 1是单键,脂族烃,芳族烃,杂环基; G 2是氢原子,脂族烃,脂环烃,芳族烃,杂环基; A <5>是单键NR; R 2是H,卤素,脂族烃,脂环烃,芳烃,杂环; NR 6 CO 2,NRCO,NRCONR,CONR,COO,O等单键。 R 3是H,卤素,硝基,饱和脂族烃,脂环烃,芳族烃,杂环; 当A <6> CR-CR或C≡C时; R 3可以是三甲基甲硅烷基,甲酰基,酰基,羧基,烷氧基羰基,氨基甲酰基,烷基氨基甲酰基或氰基; R为H或脂族烃基。
摘要:
A connector 21 comprises a receptacle housing 26 which is affixed to one wiring element 22 and a plug housing 27 which is affixed to another wiring element 24; projecting parts 26c which project in the direction of the other housing 27 in the vicinity of the floor surface 26b of the receptacle housing 26 during the engagement of the housings 26 and 27 are provided in one or the other of the inner surface of the side walls 26a of the receptacle housing 26 and the side surfaces 27a of plug housing 27, and the dimensions c1 of a fitting gap between the two housings 26 and 27 at these projecting parts 26b is set so as to be smaller than the dimensions c2 of a fitting gap between the housings 26 and 27 at parts other than the projecting parts 26c.
摘要:
An energy supply system for supplying, in system interconnection, power received at a power receiving equipment from a power plant and power generated by a fuel cell to a power consuming installation, and supplying heat generated by the fuel cell to a heat consuming installation. This system includes an operation amount computing device for computing an amount of operation of the fuel cell to minimize an equation y=aXL+bXM+cXN, in response to an energy demand of the power consuming installation and heat consuming installation. A control device controls the fuel cell to satisfy the amount of operation computed. The system supplies energy in optimal conditions with respect to the cost borne by an energy consumer, consumption of primary energy, and release of environmental pollutants. Energy is effectively used from the standpoint of the energy consumer and a national point of view.
摘要:
A novel process for manufacturing 16-substituted .DELTA..sup.7 -prostaglandin Es, which include compounds expressed by the following formula (I), their enanantiomers, or their mixtures of arbitrary mixing ratio, ##STR1## wherein R.sup.1 indicates COOR.sup.2, CH.sub.2 OR.sup.3, or COCH.sub.2 OR.sup.3, in which R.sup.2 indicates a hydrogen atom, a substituted or unsubstituted C.sub.1 -C.sub.10 alkyl group, a substituted or unsubstituted C.sub.3 -C.sub.10 cycloalkyl group, or a substituted or unsubstituted phenyl group, and R.sup.3 indicates a hydrogen atom, a tri(C.sub.1 -C.sub.7) hydrocarbon silyl group, a group which forms an acetal bond together with the oxygen atom of a hydroxyl group, or a C.sub.2 -C.sub.7 acyl group; R.sup.4 and R.sup.5 are identical or different, each representing a hydrogen atom, a tri(C.sub.1 -C.sub.7) hydrocarbon silyl group, or a group which forms an acetal bond together with the oxygen atom of a hydroxyl group; R.sup.6 indicates a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group, or a vinyl group; R.sup.7 indicates a linear or branched C.sub.3 -C.sub.8 alkyl group, an alkyenyl group, or an alkynyl group, which may contain an oxygen atom; a phenyl group, a phenoxy group, or a C.sub.3 - C.sub.10 cycloalkyl group, which may be substituted; or a linear or branched C.sub.1 -C.sub.5 alkyl group which is substituted by a C.sub.1 -C.sub.6 alkoxy group, a phenyl group, a phenoxy group, or a C.sub.3 -C.sub.10 cycloalkyl group, which may be substituted; and Y indicates CH.sub.2 X or XCH.sub.2, in which X represents an ethylene group, a cis -or trans-vinylene group, or an ethynylene group.
摘要:
A compound of the formula ##STR1## wherein Y represents an arylene group optionally substituted by a halogen atom, an arylsulfonyl group or an acyl group, Z represents a 1,2-naphthylene, 2,3-naphthylene, 1,8-naphthylene or 2, 2'-biphenylene group optionally substituted by a halogen atom, and either one or both of the rings A and B optionally contain a substituent. This compound can be obtained by reacting a quinoline derivative with an aryldicarboxylic acid or its reactive derivative, and if desired, halogenating the resulting product. A yellow organic pigment comprising this compound as a coloring ingredient is useful for coloring polymeric materials.