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公开(公告)号：US11254950B2
公开(公告)日：2022-02-22
申请号：US16805362
申请日：2020-02-28
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Arlene R. Howe , Jennifer L. Lutke , Eric Van Fleet
Abstract: Nucleotide sequences are disclosed encoding novel, insecticidal TIC4747 and related proteins exhibiting Hemipteran and Lepidopteran inhibitory activity, as well as fragments thereof. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing a polynucleotide construct encoding one or more of the toxin proteins within the TIC4747-related protein toxin class.
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公开(公告)号：US10669317B2
公开(公告)日：2020-06-02
申请号：US15849012
申请日：2017-12-20
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas A. Cerruti , Crystal L. Dart , Leigh H. English , Stanislaw Flasinski , Xiaoran Fu , Victor M. Guzov , Arlene R. Howe , Jay P. Morgenstern , James K. Roberts , Sara A. Salvador , Jinling Wang
IPC: C07K14/325 , C12N15/82 , A01N63/10 , C12N15/62
Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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公开(公告)号：US10465205B2
公开(公告)日：2019-11-05
申请号：US15944114
申请日：2018-04-03
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Krishnakumar Sridharan
IPC: C12N15/82 , C07K14/195 , C07K14/32 , A01N37/46 , A01N63/02
Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins are also provided.
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公开(公告)号：US20180127773A1
公开(公告)日：2018-05-10
申请号：US15848852
申请日：2017-12-20
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas A. Cerruti , Crystal L. Dart , Leigh H. English , Stanislaw Flasinski , Xiaoran Fu , Victor M. Guzov , Arlene R. Howe , Jay P. Morgenstern , James K. Roberts , Sara A. Salvador , Jinling Wang
IPC: C12N15/82
CPC classification number: C07K14/325 , A01N63/02 , C07K2319/00 , C12N15/62 , C12N15/8286 , Y02A40/162
Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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公开(公告)号：US20160319302A1
公开(公告)日：2016-11-03
申请号：US14945140
申请日：2015-11-18
Applicant: Monsanto Technology LLC
Inventor： Gregory J. Bean , David J. Bowen , Catherine A. Chay , Arlene R. Howe , Jason S. Milligan , Yong Yin
IPC: C12N15/82 , A01N63/02 , C07K14/195
Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.
Abstract translation: 公开了对鞘翅目和鳞翅目害虫物质具有毒性活性的杀虫蛋白，包括但不限于TIC3668，TIC3669，TIC3670，TIC4076，TIC4078，TIC4260，TIC4346，TIC4826，TIC4861，TIC4862，TIC4863和TIC-3668- 型蛋白。 提供DNA分子和构建体，其含有编码一种或多种所公开的TIC3668型蛋白质的多核苷酸序列。 提供了转基因植物，植物细胞，种子和对鳞翅目和鞘翅目昆虫侵染的植物部分，其含有编码本发明的杀虫蛋白的多核苷酸序列。 还提供了用于检测生物样品中本发明的多核苷酸或蛋白质的存在的方法，以及使用任何TIC3668型杀虫蛋白质来控制鞘翅目和鳞翅目昆虫害虫的方法。
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Patent Agency Ranking
公开(公告)号：US20250154210A1
公开(公告)日：2025-05-15
申请号：US19030863
申请日：2025-01-17
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas A. Cerruti , Crystal L. Dart , Leigh H. English , Stanislaw Flasinski , Xiaoran Fu , Victor M. Guzov , Arlene R. Howe , Jay P. Morgenstern , James K. Roberts , Sara A. Salvador , Jinling Wang
IPC: C07K14/325 , C12N15/62 , C12N15/82
Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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公开(公告)号：US12123011B2
公开(公告)日：2024-10-22
申请号：US17938016
申请日：2022-10-04
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Jason S. Milligan , James K. Roberts , Yong Yin
IPC: C12N15/82
CPC classification number: C12N15/8286
Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.
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公开(公告)号：US12104162B2
公开(公告)日：2024-10-01
申请号：US17854198
申请日：2022-06-30
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Arlene R. Howe , Kimberley M. Wegener
CPC classification number: C12N15/8286 , A01N63/23 , A01N63/50 , A01P7/04 , C07K14/32
Abstract: Pesticidal protein exhibiting toxic activity against Lepidopteran and Hemipteran pest species are disclosed, and include, but are not limited to, TIC2199. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the disclosed pesticidal protein. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Lepidopteran and Hemipteran species pests using TIC2199 pesticidal protein are also provided.
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公开(公告)号：US11981908B2
公开(公告)日：2024-05-14
申请号：US17575318
申请日：2022-01-13
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Krishnakumar Sridharan
IPC: C12N15/82 , A01N37/46 , A01N63/50 , C07K14/195 , C07K14/32
CPC classification number: C12N15/8286 , A01N37/46 , A01N63/50 , C07K14/195 , C07K14/32 , C07K2319/00 , A01N63/50 , A01N63/20
Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins are also provided.
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公开(公告)号：US11512324B2
公开(公告)日：2022-11-29
申请号：US16580583
申请日：2019-09-24
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe
IPC: C12N15/82 , C07K14/325 , A01N63/50 , G01N33/569 , G01N33/00 , A01N63/10
Abstract: A pesticidal protein class of PirA, PirB, and PirAB fusion proteins exhibiting toxic activity against Coleopteran, Lepidopteran, and Hemipteran pest species is disclosed. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the PirA, PirB, and PirAB fusion proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran, Lepidopteran, and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the PirA, PirB, and PirAB fusion proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, and Hemipteran species pests using the PirA, PirB, and PirAB fusion proteins are also provided.
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