公开(公告)号：US11987603B2

公开(公告)日：2024-05-21

申请号：US17698936

申请日：2022-03-18

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Thomas A. Cerruti ,  Crystal L. Dart ,  Leigh H. English ,  Stanislaw Flasinski ,  Xiaoran Fu ,  Victor M. Guzov ,  Arlene R. Howe ,  Jay P. Morgenstern ,  James K. Roberts ,  Sara A. Salvador ,  Jinling Wang

IPC: C07K14/325 ,  A01N37/46 ,  C12N15/82 ,  C12N15/62

CPC classification number: C07K14/325 ,  A01N37/46 ,  C12N15/8286 ,  C07K2319/00 ,  C12N15/62 ,  Y02A40/146

Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.

公开(公告)号：US20220281927A1

公开(公告)日：2022-09-08

申请号：US17698936

申请日：2022-03-18

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Thomas A. Cerruti ,  Crystal L. Dart ,  Leigh H. English ,  Stanislaw Flasinski ,  Xiaoran Fu ,  Victor M. Guzov ,  Arlene R. Howe ,  Jay P. Morgenstern ,  James K. Roberts ,  Sara A. Salvador ,  Jinling Wang

IPC: C07K14/325 ,  C12N15/82 ,  A01N37/46

Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.

公开(公告)号：US11274138B2

公开(公告)日：2022-03-15

申请号：US15940962

申请日：2018-03-29

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： Edward Kraft ,  Renata Bolognesi ,  Artem Evdokimov ,  Farhad Moshiri ,  Meiying Zheng ,  Victor M. Guzov

IPC: C07K14/705 ,  G01N33/50 ,  C12N9/16 ,  C07K14/435 ,  C12N9/48 ,  C12N9/64 ,  C12N15/63 ,  C12N5/10

Abstract: The invention relates to identification and characterization of recombinant DNA and polypeptides for specific Bt toxin receptors. In particular, the Bt toxin receptors of the invention include those derived from the Lepidopteran super family including the species Trichoplusiani ni, Pseudoplusia includens, Helicoverpa zea, and Spodoptera frugiperda. The receptors of the invention further include those derived from the Coleopteran super family and particularly from the species Diabrotica virgifera virgifera. The recombinant DNA and polypeptides so provided are useful in the identification and design of novel Bt toxin receptor ligands including novel or improved insecticidal toxins for use in a variety of agricultural applications. Materials and methods for identifying novel toxins are also disclosed herein. The invention also provides methods for selecting toxins to combine to control insect populations by manipulating Bt toxin receptor.

公开(公告)号：US10703782B2

公开(公告)日：2020-07-07

申请号：US15868676

申请日：2018-01-11

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  David J. Bowen ,  Catherine A. Chay ,  David J. Chi ,  William P. Clinton ,  Crystal L. Dart ,  Leigh English ,  Stanislaw Flasinski ,  Victor M. Guzov ,  Kevin A. Jarrell ,  Uma R. Kesanapalli ,  Thomas M. Malvar ,  Robert M. McCarroll ,  Jason S. Milligan ,  Jay P. Morgenstern ,  Deborah G. Rucker ,  Sara A. Salvador ,  Temple F. Smith ,  Carlos E. Soto ,  Collin M. Stultz ,  Brian M. Turczyk ,  Ty T. Vaughn ,  Moritz W. F. Von Rechenberg

IPC: C07K14/325 ,  C12N15/82

Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.

公开(公告)号：US20180328916A1

公开(公告)日：2018-11-15

申请号：US15940962

申请日：2018-03-29

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： Edward Kraft ,  Renata Bolognesi ,  Artem Evdokimov ,  Farhad Moshiri ,  Meiying Zheng ,  Victor M. Guzov

IPC: G01N33/50 ,  C07K16/28 ,  G01N33/68 ,  C07K16/40 ,  C12N9/16 ,  C12N9/64 ,  C12N9/48 ,  C07K14/705 ,  C07K14/435

CPC classification number: G01N33/5085 ,  C07K14/43563 ,  C07K14/705 ,  C07K16/28 ,  C07K16/40 ,  C12N9/16 ,  C12N9/485 ,  C12N9/6416 ,  G01N33/5014 ,  G01N33/6845 ,  G01N2500/04 ,  G01N2500/10

Abstract: The invention relates to identification and characterization of recombinant DNA and polypeptides for specific Bt toxin receptors. In particular, the Bt toxin receptors of the invention include those derived from the Lepidopteran super family including the species Trichoplusiani ni, Pseudoplusia includens, Helicoverpa zea, and Spodoptera frugiperda. The receptors of the invention further include those derived from the Coleopteran super family and particularly from the species Diabrotica virgifera virgifera. The recombinant DNA and polypeptides so provided are useful in the identification and design of novel Bt toxin receptor ligands including novel or improved insecticidal toxins for use in a variety of agricultural applications. Materials and methods for identifying novel toxins are also disclosed herein. The invention also provides methods for selecting toxins to combine to control insect populations by manipulating Bt toxin receptor.

公开(公告)号：US20180127775A1

公开(公告)日：2018-05-10

申请号：US15849218

申请日：2017-12-20

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Thomas A. Cerruti ,  Crystal L. Dart ,  Leigh H. English ,  Stanislaw Flasinski ,  Xiaoran Fu ,  Victor M. Guzov ,  Arlene R. Howe ,  Jay P. Morgenstern ,  James K. Roberts ,  Sara A. Salvador ,  Jinling Wang

IPC: C12N15/82

CPC classification number: C07K14/325 ,  A01N63/02 ,  C07K2319/00 ,  C12N15/62 ,  C12N15/8286 ,  Y02A40/162

Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.