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公开(公告)号：US12240874B2
公开(公告)日：2025-03-04
申请号：US18319022
申请日：2023-05-17
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , David J. Bowen , Catherine A. Chay , David J. Chi , William P. Clinton , Crystal L. Dart , Leigh English , Stanislaw Flasinski , Victor M. Guzov , Kevin A. Jarrell , Uma R. Kesanapalli , Thomas M. Malvar , Robert M. McCarroll , Jason S. Milligan , Jay P. Morgenstern , Deborah G. Rucker , Sara A. Salvador , Temple F. Smith , Carlos E. Soto , Collin M. Stultz , Brian M. Turczyk , Ty T. Vaughn , Moritz W. F. Von Rechenberg
IPC: C07K14/325 , A01N63/50 , C12N15/82
Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.
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公开(公告)号：US09976139B2
公开(公告)日：2018-05-22
申请号：US14664659
申请日：2015-03-20
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： Shihshieh Huang , Thomas M. Malvar , Michael H. Luethy
CPC classification number: C12N15/113 , A61K48/00 , C07H21/02 , C12N9/0028 , C12N15/111 , C12N15/8218 , C12N15/8251 , C12N15/8254 , C12N2310/11 , C12N2310/111 , C12N2310/14 , C12N2310/53 , C12N2330/30
Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5′ to 3′ order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.
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公开(公告)号：US09708620B2
公开(公告)日：2017-07-18
申请号：US14582303
申请日：2014-12-24
Applicant: Monsanto Technology LLC
Inventor： Edwards M. Allen , Larry A. Gilbertson , Sara E. Heisel , Shihshieh Huang , Elysia K. Krieger , Thomas M. Malvar
IPC: C12N15/82 , C12N15/113
CPC classification number: C12N15/8218 , C12N15/113 , C12N15/8216 , C12N15/8217 , C12N15/8286 , C12N2310/113 , Y02A40/162
Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
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公开(公告)号：US20170029844A1
公开(公告)日：2017-02-02
申请号：US15217695
申请日：2016-07-22
Applicant: Monsanto Technology LLC
Inventor： Timothy K. Ball , Artem G. Evdokimov , Larry A. Gilbertson , Victor M. Guzov , Jeffrey A. Haas , Qing Huai , Sergey Ivashuta , Melissa M. Kemp , Yifei Kong , Thomas M. Malvar , Byron V. Olsen , Parthasarathy Ramaseshadri , Brian E. Weiner
CPC classification number: C12N15/8286 , A01N37/44 , A01N37/46 , C07K14/325 , Y02A40/162
Abstract: Pesticidal proteins are provided that combine two or more modes of action into a single molecule. These pesticidal proteins therefor exhibit greater efficacy and/or durability of resistance, for the purposes of pest control, and can be utilized for pest control by provision in the diet of a pest organism, or by topical application to crop plants and/or pests. Methods and compositions for producing and using such proteins are also provided.
Abstract translation: 提供了将两种或多种作用模式组合成单个分子的杀虫蛋白质。 这些杀虫蛋白为了有害生物控制的目的而具有较高的抗性和/或耐久性，并且可以通过在有害生物的饮食中提供病虫害防治，或通过局部应用于作物植物和/或害虫来利用。 还提供了用于生产和使用这些蛋白质的方法和组合物。
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公开(公告)号：US20150089683A1
公开(公告)日：2015-03-26
申请号：US14395636
申请日：2013-03-06
Applicant: Monsanto Technology LLC
Inventor： Mark Scott Abad , Pranesh Badami , Amarjit Basra , Erin Bell , Christopher P. Bonin , Paolo Castiglioni , Eric R. Cerny , Jaishree M. Chittoor-Vijayanath , Paul Chomet , Todd Dezwaan , Stephen Duff , Michael D. Edgerton , Barry S. Goldman , Balasulojini Karunanandaa , Kempagangaiah Krishnamurthy , Ping Li , Adrian A. Lund , Llinda Lutfiyya , Thomas M. Malvar , Donald E. Nelson , Monnanda S. Rajani , Dhanalakshmi Ramachandra , Thomas G. Ruff , Sara Salvador , S. Sangeetha , Char Shobha , Jeffrey M. Staub , Virginia Ursin , Tyamagondlu V. Venkatesh , Kammaradi R. Vidya , Xiaoyun Wu , Sean Yang , Jianmin Zhao
CPC classification number: C12N15/8261 , A01H1/02 , C07K14/415 , C07K14/81 , C12N5/04 , C12N9/0006 , C12N15/8201 , C12N15/8205 , C12N15/825 , C12N15/8271 , C12N15/8273 , C12Y101/01049 , Y02A40/146
Abstract: This disclosure provides transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.
Abstract translation: 本公开提供具有增强性状的转基因植物，例如增加的产量，增加的氮利用效率和增强的耐旱性; 这些转基因植物的繁殖体，后代和田间作物; 以及制备和使用这些转基因植物的方法。 本公开还提供了从这种转基因植物产生杂种种子的方法，种植这种种子并选择具有增强特征的后代植物。 还公开了具有改变的表型的转基因植物，其可用于筛选和选择所需增强性状的转基因事件。
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Patent Agency Ranking
公开(公告)号：US20240117374A1
公开(公告)日：2024-04-11
申请号：US18497825
申请日：2023-10-30
Applicant: Monsanto Technology LLC
Inventor： Timothy K. Ball , Artem G. Evdokimov , Larry A. Gilbertson , Victor M. Guzov , Jeffrey A. Haas , Qing Huai , Sergey Ivashuta , Melissa M. Kemp , Yifei Kong , Thomas M. Malvar , Byron V. Olsen , Parthasarathy Ramaseshadri , Brian E. Weiner
IPC: C12N15/82 , A01N37/44 , A01N37/46 , C07K14/325
CPC classification number: C12N15/8286 , A01N37/44 , A01N37/46 , C07K14/325 , Y02A40/146
Abstract: Pesticidal proteins are provided that combine two or more modes of action into a single molecule. These pesticidal proteins therefor exhibit greater efficacy and/or durability of resistance, for the purposes of pest control, and can be utilized for pest control by provision in the diet of a pest organism, or by topical application to crop plants and/or pests. Methods and compositions for producing and using such proteins are also provided.
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公开(公告)号：US11702455B2
公开(公告)日：2023-07-18
申请号：US16894459
申请日：2020-06-05
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , David J. Bowen , Catherine A. Chay , David J. Chi , William P. Clinton , Crystal L. Dart , Leigh English , Stanislaw Flasinski , Victor M. Guzov , Kevin A. Jarrell , Uma R. Kesanapalli , Thomas M. Malvar , Robert M. McCarroll , Jason S. Milligan , Jay P. Morgenstern , Deborah G. Rucker , Sara A. Salvador , Temple F. Smith , Carlos E. Soto , Collin M. Stultz , Brian M. Turczyk , Ty T. Vaughn , Moritz W. F. Von Rechenberg
IPC: C07K14/325 , C12N15/82 , A01N63/50
CPC classification number: C07K14/325 , A01N63/50 , C12N15/8286 , Y02A40/146 , A01N63/50 , A01N63/23 , A01N63/50 , A01N63/50
Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.
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公开(公告)号：US20180007856A9
公开(公告)日：2018-01-11
申请号：US13914505
申请日：2013-06-10
Applicant: Monsanto Technology LLC
Inventor： Michael H. Luethy , Thomas M. Malvar , Shihshieh Huang
IPC: A01H5/10 , C12N9/06 , C07K14/415 , C12N15/82
CPC classification number: A01H5/10 , A23K10/30 , A23L7/198 , C07K14/415 , C12N9/0028 , C12N15/8218 , C12N15/8247 , C12N15/8251 , C12N15/8254
Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5′ to 3′ order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
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9.发明申请公开(公告)号：US20150184179A1
公开(公告)日：2015-07-02
申请号：US14582303
申请日：2014-12-24
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： Edwards M. Allen , Larry A. Gilbertson , Sara E. Heisel , Shihshieh Huang , Elysia K. Krieger , Thomas M. Malvar
IPC: C12N15/82 , C12N15/113
CPC classification number: C12N15/8218 , C12N15/113 , C12N15/8216 , C12N15/8217 , C12N15/8286 , C12N2310/113 , Y02A40/162
Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
Abstract translation: 本发明提供了分子构建体及其使用方法，包括异源miRNA识别位点的构建体，用于基因抑制的构建体，包括嵌入在非蛋白质编码序列的一侧或两侧的内含子嵌入的基因抑制元件，含有 工程miRNA或miRNA前体，以及用于抑制细胞中成熟微小RNA的产生的构建体。 还提供了含有这种构建体的转基因植物细胞，植物和种子及其使用的方法。 本发明还提供了转基因植物细胞，植物和种子，其含有重组DNA，用于靶序列的配体受控表达，其可以是内源的或外源的。 还公开了来自作物植物（包括玉米和大豆）的新miRNA和miRNA前体。
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公开(公告)号：US20140173778A1
公开(公告)日：2014-06-19
申请号：US13914505
申请日：2013-06-10
Applicant: Monsanto Technology LLC
Inventor： Michael H. Luethy , Thomas M. Malvar , Shihshieh Huang
CPC classification number: A01H5/10 , A23K10/30 , A23L7/198 , C07K14/415 , C12N9/0028 , C12N15/8218 , C12N15/8247 , C12N15/8251 , C12N15/8254
Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5′ to 3′ order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
Abstract translation: 在转基因生物体的细胞中产生以反义取向RNA环形式的反义RNA RNA基因抑制剂。 植物通过从包含5'至3'顺序的重组DNA构建体转录起可操作地连接到多于一个反义取向DNA元件和一个或多个互补DNA元件的启动子元件。
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