公开(公告)号：US10448866B1

公开(公告)日：2019-10-22

申请号：US15396774

申请日：2017-01-02

申请人： Marcelo A German ,  Mohammed Nabyl Bennouri ,  Jie Lian

发明人： Marcelo A German ,  Mohammed Nabyl Bennouri ,  Jie Lian

IPC分类号： A61B5/11 ,  A61B5/0205 ,  A61B5/0488 ,  A61B5/053 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/00 ,  G10L15/22

摘要： An electronic device tracks both calorie loss and intake for a user. The device comprises a plurality of sensors to measure user's physical activities, and provides a user interface to allow user input of activities. The device tracks these activities and estimates the calorie burned based on predefined formulas. Also through the user interface, the device allows user to input information about food or drink consumption, and then estimates the corresponding calorie intake. User input of activities and food/drink consumption can be achieved by means of voice. The electronic device also runs a software app which can provide instructions for the user with regards to activities and/or food/drink consumption. In addition, the app allows user to enter weight, together with the tracked calorie intake and loss history data, to adaptively adjust the calorie calculation formulas and the associated parameters.

公开(公告)号：US08892193B2

公开(公告)日：2014-11-18

申请号：US13329363

申请日：2011-12-19

申请人： J. Christopher Moulder ,  Jie Lian

发明人： J. Christopher Moulder ,  Jie Lian

IPC分类号： A61B5/0452 ,  A61N1/37

CPC分类号： A61N1/3704 ,  A61N1/37

摘要： A method for automatic threshold control and detection of lead failure in an implanted medical device obtains three sensing vectors for measurement of an electrocardiogram signal. A dynamic error signal is determined from the vectors, and may be used to set a detection threshold for insufficient ECG signals, and/or to passively monitor the device for indications of lead failure without performing an impedance measurement. Passive mode operation conserves battery power and enables continuous lead integrity checks. A quality factor may also be determined from the error signal, to indicate whether or not signal measurements are valid with respect to noise levels. If the detection threshold is allowed to decay between successive features of the electrocardiogram, the decay rate may be made adaptive such that it automatically adjusts to changes in heart rate or to changes in amplitude of the electrocardiogram features.

摘要翻译： 用于植入医疗装置中的铅缺陷的自动阈值控制和检测的方法获得用于测量心电图信号的三个感测向量。 从向量确定动态误差信号，并且可以用于设置不足的ECG信号的检测阈值，和/或被动地监视器件以获得引线故障的指示，而不进行阻抗测量。 被动模式操作可节省电池电量，并实现连续的导线完整性检查。 质量因子也可以从误差信号确定，以指示信号测量是否对噪声水平有效。 如果允许检测阈值在心电图的连续特征之间衰减，则可以使衰减速率自适应，使得其自动调节心率变化或心电图特征的幅度变化。

公开(公告)号：US08419645B2

公开(公告)日：2013-04-16

申请号：US13176484

申请日：2011-07-05

申请人： Jie Lian ,  Dirk Muessig

发明人： Jie Lian ,  Dirk Muessig

IPC分类号： A61B5/08

CPC分类号： A61N1/3621 ,  A61N1/36521 ,  A61N1/368 ,  A61N1/3684 ,  A61N1/3702

摘要： An implantable medical device that measures respiration parameters based on transthoracic impedance signals, and converts transthoracic impedance signals into a time series of digital values which is filtered with morphological operators to separate the signal into a respiratory component and a cardiac component. Metrics are generated based on the filtered impedance values such as respiratory rate, I/E ratio, tidal volume and minute ventilation.

摘要翻译： 基于经胸阻抗信号测量呼吸参数的可植入医疗装置，并且将经胸阻抗信号转换成数字值的时间序列，该数字值用形态运算符过滤以将信号分离成呼吸成分和心脏分量。 基于滤波的阻抗值（如呼吸频率，I / E比，潮气量和分钟通气量）产生指标。

公开(公告)号：US20130079839A1

公开(公告)日：2013-03-28

申请号：US13603418

申请日：2012-09-05

申请人： Jie Lian ,  Volker Lang ,  Hannes Kraetschmer ,  Dirk Muessig

发明人： Jie Lian ,  Volker Lang ,  Hannes Kraetschmer ,  Dirk Muessig

IPC分类号： A61N1/365

CPC分类号： A61N1/3627 ,  A61B5/0402 ,  A61N1/36521 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3686

摘要： The present disclosure refers to a heart stimulator comprising a stimulation control unit, a stimulation unit, an impedance measurement unit and an impedance evaluation unit. The stimulation control unit is operatively connected to the stimulation unit to control timing of stimulation pulses by said stimulation unit. The impedance measurement unit is configured to determine an impedance signal reflecting intracardiac impedance. The impedance evaluation unit is operatively connected to the impedance measurement unit and to the stimulation control unit and is configured to evaluate the impedance signal so as to determine an isovolumic contraction time, an isovolumic relaxation time, an ejection time and a filling time from said impedance signal. The stimulation control unit is further configured to control timing of stimulation pulses depending on a performance index.

摘要翻译： 本公开涉及包括刺激控制单元，刺激单元，阻抗测量单元和阻抗评估单元的心脏刺激器。 刺激控制单元可操作地连接到刺激单元以控制所述刺激单元的刺激脉冲的定时。 阻抗测量单元被配置为确定反映心内阻抗的阻抗信号。 阻抗评估单元可操作地连接到阻抗测量单元和刺激控制单元，并被配置为评估阻抗信号，以便确定等容收缩时间，等容弛豫时间，喷射时间和来自所述阻抗的填充时间 信号。 刺激控制单元还被配置为根据性能指标来控制刺激脉冲的定时。

公开(公告)号：US08315694B2

公开(公告)日：2012-11-20

申请号：US12252529

申请日：2008-10-16

申请人： Jie Lian ,  Dirk Muessig

发明人： Jie Lian ,  Dirk Muessig

IPC分类号： A61B5/04

CPC分类号： A61N1/3702 ,  A61N1/3621

摘要： Heart monitor for detecting ectopic beats in an input electrocardiogram signal that includes an electrocardiogram signal input and a morphological signal analyzer connected to the electrocardiogram signal input, the analyzer being adapted to generate a first time series of values representing the input electrocardiogram signal, a second signal analyzer adapted to generate generating a modified time series of values representing a trend of values of the first time series and a comparison stage being adapted to compare the first time series with the modified time series to thus detect ectopic beats. The invention further relates to a method for detecting ectopic beats in an input electrocardiogram signal that includes obtaining an electrocardiogram signal, generating from the electrocardiogram signal a first time series of values representing the input electrocardiogram signal, generating a modified time series of values representing a trend of values of the first time series and comparing the first time series with the modified time series to thus detect ectopic beats.

摘要翻译： 用于检测输入心电图信号中的异位搏动的心脏监视器，其包括心电图信号输入和连接到所述心电图信号输入的形态信号分析器，所述分析器适于产生表示所述输入心电图信号的第一时间序列值，第二信号 分析器，其适于产生生成表示第一时间序列的值的趋势的值的修改的时间序列，并且比较阶段适于将第一时间序列与修改的时间序列进行比较，从而检测异位跳动。 本发明还涉及一种用于检测输入心电图信号中的异位搏动的方法，包括获得心电图信号，从心电图信号产生表示输入心电图信号的第一时间序列值，产生表示趋势的值的修改时间序列 的第一时间序列的值，并将第一时间序列与修改的时间序列进行比较，从而检测异位跳动。

公开(公告)号：US08019407B2

公开(公告)日：2011-09-13

申请号：US12257578

申请日：2008-10-24

申请人： Jie Lian ,  Dirk Muessig

发明人： Jie Lian ,  Dirk Muessig

IPC分类号： A61B5/04

CPC分类号： A61B5/0452 ,  A61B5/02405 ,  A61B5/7264 ,  A61N1/3702 ,  G06K9/0053 ,  G06K9/00557

摘要： A heart monitor for processing input signals that represent periodically reoccurring events in a sequence of heart cycles. According to the invention graphical data representing a scatter plot of at least two dimensions, one dimension representing interval duration or its inverse and the other dimension representing change of duration or its inverse, respectively, are generated. The scatter plot comprises data points of which each data point represents heart interval duration or its inverse plotted against the change of duration with respect to a neighboring interval or the inverse of said change respectively.

摘要翻译： 心脏监护仪，用于处理在心脏周期序列中代表周期性重现的事件的输入信号。 根据本发明，生成表示至少二维的散点图的图形数据，分别表示间隔持续时间的一维或其逆，以及分别表示持续时间或其逆的变化的另一维度。 分散图包括数据点，其中每个数据点表示心脏间隔持续时间或其相对于相对间隔的持续时间变化或所述变化的倒数的变化绘制。

公开(公告)号：US08019406B2

公开(公告)日：2011-09-13

申请号：US12045142

申请日：2008-03-10

申请人： Jie Lian ,  Dirk Muessig ,  Volker Lang

发明人： Jie Lian ,  Dirk Muessig ,  Volker Lang

IPC分类号： A61N1/362 ,  A61B5/0452

CPC分类号： A61B5/04011 ,  A61B5/0452 ,  A61B5/7275 ,  A61N1/3622 ,  A61N1/37282 ,  G06F19/00

摘要： A medical device and a method is suggested for assessing the risk of R on T events. The device comprises a memory, input means for acquiring or receiving an electrogram signal and processing means. The processing means are adapted to detect R-wave and T-waves represented by said electrogram, establish a QT-RR regression model based detected R-waves and T-waves, estimate a vulnerable period, and store estimated vulnerable period data in said memory. Likewise, the method comprises the steps of to detecting R-wave and T-waves represented by an electrogram, establishing a QT-RR regression model based detected R-waves and T-waves, estimating a vulnerable period, and storing estimated vulnerable period data.

摘要翻译： 建议使用医疗设备和方法来评估R on T事件的风险。 该装置包括存储器，用于获取或接收电描记图信号的输入装置和处理装置。 处理装置适于检测由所述电描记图表示的R波和T波，建立基于检测到的R波和T波的QT-RR回归模型，估计易受伤害的周期，并将估计的脆弱周期数据存储在所述存储器中 。 同样地，该方法包括以下步骤：检测由电描记图表示的R波和T波，建立基于检测的R波和T波的QT-RR回归模型，估计脆弱时期，以及存储估计的脆弱周期数据 。

公开(公告)号：US20110022438A1

公开(公告)日：2011-01-27

申请号：US12509745

申请日：2009-07-27

申请人： Jie Lian

发明人： Jie Lian

IPC分类号： G06Q10/00 ,  G06Q30/00

CPC分类号： G06Q10/06 ,  G06Q10/1093 ,  G06Q30/016

摘要： Conventional resource allocation process has intrinsic inefficiency because of the resource fragmentation. A solution is provided to defragment the resource so that the customers' requests are better served and provider's resource utilization rate is improved.

摘要翻译： 由于资源分散，传统的资源分配过程具有内在的低效率。 提供解决方案来对资源进行碎片整理，以便更好地服务客户的请求，提高资源利用率。

公开(公告)号：US20070265670A1

公开(公告)日：2007-11-15

申请号：US11383232

申请日：2006-05-15

申请人： Volker Lang ,  Jie Lian ,  Dirk Mussig

发明人： Volker Lang ,  Jie Lian ,  Dirk Mussig

IPC分类号： A61N1/362

CPC分类号： A61N1/3622 ,  A61N1/3682

摘要： An implantable cardiac electrostimulator comprising an atrial sensing channel for processing intracardiac electrogram signals and for detecting signals corresponding to atrial activity and for generating an atrial sense event signal upon detection of a signal corresponding to atrial activity, a ventricular sensing channel for processing intracardiac electrogram signals and for detecting signals corresponding to ventricular activity and for generating a ventricular sense event signal upon detection of a signal corresponding to ventricular activity, a VES detector being operatively connected to said atrial and ventricular sensing channel and being adapted to detect ventricular extrasystoles an atrial stimulation pulse generator a ventricular stimulation pulse generator a stimulation control unit being operatively connected to said atrial stimulation pulse generator and said ventricular stimulation pulse generator. The stimulation control unit is adapted to determine a scheduled time of delivery of an atrial stimulation pulse (T(A)) and a scheduled time of delivery of ventricular stimulation pulse (T(V)). The stimulation control unit is further adapted to trigger said atrial stimulation pulse generator or said ventricular stimulation pulse generator at the scheduled point of time T(A) or T(V), respectively, if no atrial sense event signal is generated before time out of an atrial escape interval (VAI), said atrial escape interval timing out at T(A), or if no ventricular sense event signal is generated before time out of a ventricular escape interval (VEI), said ventricular escape interval timing out at T(V), respectively. T(A) und T(V) are determined depending upon detection of a ventricular extra systole while maintaining a proper atrioventricular synchrony by setting a physiologically adequate A-V-delay between T(A) and corresponding T(V).

摘要翻译： 一种可植入心脏电刺激器，包括用于处理心内电描记信号的心房感测通道，并且用于检测对应于心房活动的信号，并且用于在检测到对应于心房活动的信号时产生心房感测事件信号;心室感测通道，用于处理心内电描记图信号;以及 用于检测对应于心室活动的信号，并且在检测到对应于心室活动的信号时产生心室感测事件信号，VES检测器可操作地连接到所述心房和心室感测通道，并且适于检测心室收缩期心房刺激脉冲发生器 心室刺激脉冲发生器，其可操作地连接到所述心房刺激脉冲发生器和所述心室刺激脉冲发生器的刺激控制单元。 刺激控制单元适于确定预定的心房刺激脉冲（T（A））的输送时间和心室刺激脉冲（T（V））的预定运送时间。 刺激控制单元还适于在预定的时间点T（A）或T（V））分别触发所述心房刺激脉冲发生器或所述心室刺激脉冲发生器，如果在超时之前没有产生心房感测事件信号 心房逸出间隔（VAI），所述心房逃逸间隔在T（A）处超时，或者如果在心室逸出间隔（VEI）之前的时间之前没有产生心室感测事件信号，则所述心室逃逸间隔在T（ V）。 通过在T（A）和相应的T（V）之间设置一个生理上足够的A-V延迟来维持室内额外心脏收缩，同时保持适当的房室同步来确定T（A）和T（V）。

公开(公告)号：US20140305537A1

公开(公告)日：2014-10-16

申请号：US13860471

申请日：2013-04-10

申请人： Jie Lian

发明人： Jie Lian

IPC分类号： B60S5/02 ,  B67D7/04

CPC分类号： B60S5/02

摘要： Conventional fueling station has an intrinsic limitation of congested traffic flow, leading to under utilization of fuel dispensers and causing long waiting lines. This invention discloses a novel structure of a fueling station and the method of improving the traffic flow in the fueling station. The disclosed fueling station comprises a passage for entrance, a passage for exit, at least a sequence of two or more fuel dispensers arranged sequentially between said passage for entrance and said passage for exit, wherein each fuel dispenser has at least one fueling space, and said fueling space is configured to enable a vehicle to move into and out of said fueling space without being hindered by another vehicle at a different fueling space.

摘要翻译： 传统的加油站具有拥挤交通流量的固有限制，导致燃料分配器利用不足，导致长时间的等待线路。 本发明公开了一种加油站的新颖结构以及改善加油站的交通流量的方法。 所公开的加油站包括用于进入的通道，用于出口的通道，至少一系列两个或更多个燃料分配器，其顺序布置在所述入口通道和所述出口通道之间，其中每个燃料分配器具有至少一个加油空间，以及 所述燃料供给空间构造成使得车辆能够进入和离开所述加油空间，而不会被不同加油空间的另一车辆阻碍。