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公开(公告)号：US11717611B2
公开(公告)日：2023-08-08
申请号：US16462139
申请日：2017-11-17
申请人： Owen Mumford Limited
发明人： Toby Cowe , Colin Webb
CPC分类号： A61M5/2066 , A61M5/2033 , A61M5/2429 , A61M5/3158 , A61M5/31596 , A61M2005/206 , A61M2005/2073 , A61M2005/3128 , A61M2005/31518
摘要： A medicament delivery device (100) for delivery of medicament from a cartridge (10) into an injection site, through a cannula (134). The cartridge has a medicament chamber (14) with an outlet (15), and a sealing element (16) for closing the outlet (15). The device has a housing (102) for receiving the cartridge (10), and a drive mechanism (200) to expel the medicament from the device upon activation of the drive mechanism (200). The device has a connection arrangement (199) comprising a hub (166) and spring means (184) for driving relative movement between the hub (166) and the cartridge (10) upon operation of an operating member (190). The operating member switches the connection arrangement (199) from an unconnected configuration to a connected configuration, in which the hub (166) cooperates with the cartridge (10) to open the outlet (15). When connected, fluid may flow between the chamber (14) and the cannula (134).
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公开(公告)号：US11311673B2
公开(公告)日：2022-04-26
申请号：US16462038
申请日：2017-11-17
申请人： Owen Mumford Limited
发明人： Toby Cowe
摘要： A device (200) for mixing first and second substances. The device comprises a first container (100) for storage of the first substance and a second container (150) received in the first container (100) and for storage of the second substance. An outlet (112) is disposed at the distal end of the first container (100). Valve means (180) are provided for closing a distal end of the second container (150) and a proximal end of the first container (100). A stopper means (166) closes a proximal end of the second chamber (152) and is movable with respect to the second container (150). An operating mechanism drives relative movement between the first and second containers for causing displacement of the second substance into the first chamber (102) through the valve means (180) when the outlet (112) is closed, for mixing the first and second substances in a mixing stroke of the device.
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公开(公告)号：US11246987B2
公开(公告)日：2022-02-15
申请号：US16093847
申请日：2017-04-27
申请人： Owen Mumford Limited
发明人： Toby Cowe , Jake Mallon
摘要： A medicament delivery device (100) for a delivery of a medicament from a container (12) through a cannula (16). The device comprises a chassis (300), a carriage (200), and an insertion spring (70) for biasing the carriage (200) for movement in an insertion direction with respect to the chassis (300) from a starting position in which the cannula (16) is shrouded to an insertion position in which the cannula (16) is extended. A drive mechanism (400) is provided for driving a stopper (22) of the container (12) to expel the medicament. The drive mechanism (400) is carriage by the carriage (200) and comprises a movable drive member (404), a drive means (40) for applying a driving force to the drive member (404), and a force transmission means (406) for transmitting the driving force to the stopper (22). The drive means (40) is arranged around or alongside at least part of the force transmission means (406).
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公开(公告)号：US11065388B2
公开(公告)日：2021-07-20
申请号：US15739449
申请日：2016-07-13
申请人： Owen Mumford Limited
发明人： Toby Cowe , Timothy Evans , Colin Webb , Jake Mallon
IPC分类号： A61M5/24
摘要： A cartridge (100) for packaging a medicament and being suitable for use with multiple different types of dosing device is described, together with dosing devices and adaptors for dosing devices. The cartridge includes a generally tubular body (102) having an interior cavity (104), a closure member (106) disposed at a distal end of the body and comprising a sealing element (128), a piston member (108) disposed in the cavity to contain the medicament between the piston member and the sealing element (128), a coupling element (114) disposed at the distal end of the body for coupling the cartridge to a dosing device (200) or to an adaptor for a dosing device, and a seal arrangement (126, 129) for receiving a sealing element release member (214) of the dosing device or adaptor. The coupling element (114) is arranged for engagement with an engagement part (220) of the dosing device or adaptor to clip the cartridge (100) to the dosing device or adaptor (200) upon insertion of the cartridge to the dosing device or adaptor, and the seal arrangement (126, 129) is disposed distally with respect to the sealing element (128) and is arranged to form a seal around the release member (214; 254) when the cartridge is coupled to the dosing device or adaptor.
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公开(公告)号：US10722654B2
公开(公告)日：2020-07-28
申请号：US15119479
申请日：2015-02-18
申请人： Owen Mumford Limited
发明人： Toby Cowe , Cosimo Santella , Colin Plimmer
摘要： An injection device (1) includes a housing (20) for receiving a cartridge (30) of medicament in use; a drive element (12), moveable from a first position to a second position to expel a dose from said cartridge, and wherein the drive element comprises an electrically-operated indicator module (40) for generating an indication corresponding to the stage of use of the device. The indicator module (40) may be contained within the drive element, for example within an interior of the drive element and may include an audible indicator such as e.g. a sounder or loudspeaker, and a visual indicator such as e.g. one or more LEDs arranged to provide e.g. colour-coded signals.
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公开(公告)号：US20200061304A1
公开(公告)日：2020-02-27
申请号：US16659950
申请日：2019-10-22
申请人： Owen Mumford Limited
发明人： Toby Cowe , Oliver Anderson
摘要： A needle assembly is disclosed, for use with an injection device. The needle assembly comprises a needle hub (20) having a needle (22) and a needle shield (40) arranged for relative axial movement with respect to the needle hub, between a retracted position in which the tip of the needle projects beyond a forward end of the shield and an extended position in which the tip of the needle does not project beyond the forward end of the shield. The needle shield (40) is axially biased towards the extended position. The needle shield (40) is further arranged to be torsionally biased for relative rotational movement with respect to the needle hub (20).
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公开(公告)号：US09981086B2
公开(公告)日：2018-05-29
申请号：US14769949
申请日：2014-02-27
申请人： OWEN MUMFORD LIMITED
CPC分类号： A61M5/2033 , A61M5/31571 , A61M5/3204 , A61M2005/2073 , A61M2005/208 , A61M2005/2496
摘要： An automatic injection device for delivering a dose from a medicine containing syringe includes a housing for containing the syringe, a force applicator for applying a force to eject medicine from the syringe, a trigger coupled to the force applicator for releasing the force applicator to cause an injection, a boot covering a needle attached to the syringe to protect and maintain sterility of the needle, and a mechanical interlock. The mechanical interlock prevents actuation of the trigger prior to removal of the boot. When the boot is removed, the mechanical interlock allows for actuation of the trigger.
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公开(公告)号：US20170007765A1
公开(公告)日：2017-01-12
申请号：US15119479
申请日：2015-02-18
申请人： OWEN MUMFORD LIMITED
发明人： Toby Cowe , Cosimo Santella , Colin Plimmer
摘要： An injection device (1) includes a housing (20) for receiving a cartridge (30) of medicament in use; a drive element (12), moveable from a first position to a second position to expel a dose from said cartridge, and wherein the drive element comprises an electrically-operated indicator module (40) for generating an indication corresponding to the stage of use of the device. The indicator module (40) may be contained within the drive element, for example within an interior of the drive element and may include an audible indicator such as e.g. a sounder or loudspeaker, and a visual indicator such as e.g. one or more LEDs arranged to provide e.g. colour-coded signals.
摘要翻译： 注射装置（1）包括用于接收使用中的药物的药筒（30）的壳体（20） 驱动元件（12），其可从第一位置移动到第二位置以从所述盒排出剂量，并且其中所述驱动元件包括用于产生对应于使用阶段的指示的电动操作指示器模块（40） 装置。 指示器模块（40）可以包含在驱动元件内，例如在驱动元件的内部内，并且可以包括可听指示器，例如， 发声器或扬声器，以及视觉指示器，例如， 一个或多个LED布置成提供例如 彩色编码信号。
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公开(公告)号：US20160193415A1
公开(公告)日：2016-07-07
申请号：US14910155
申请日：2014-08-05
申请人： OWEN MUMFORD LIMITED
发明人： Toby Cowe
IPC分类号： A61M5/315
CPC分类号： A61M5/3157 , A61M5/2033 , A61M5/31511 , A61M2005/206 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： An injection device is disclosed which comprise a housing (10), a plunger (40) for expressing a medicament from a syringe (20) and an actuation mechanism (30). The actuation mechanism (30) is arranged in use to move the plunger (40) between a first rearward position and a second forward position to express a dose from the syringe (20). The injector device further comprises an injection activation sensor (50), arranged for example to provide an end of dose indication. The sensor (50) comprises an elongate flexible member. The flexible member has a first end (52) connected to the plunger (40) or actuation mechanism (30) such that actuation motion of the injection device acts to move the elongate flexible member (50) relative to the housing. Movement of the elongate member (50) triggers a response to the injection such as an audible and/or tactile injection complete indication.
摘要翻译： 公开了一种注射装置，其包括壳体（10），用于从注射器（20）和致动机构（30）表达药物的柱塞（40）。 致动机构（30）在使用中布置成使柱塞（40）在第一后部位置和第二向前位置之间移动以表示来自注射器（20）的剂量。 注射器装置还包括注射活化传感器（50），其被配置为例如提供剂量指示的结束。 传感器（50）包括细长的柔性构件。 柔性构件具有连接到柱塞（40）或致动机构（30）的第一端（52），使得注射装置的致动运动用于相对于壳体移动细长柔性构件（50）。 细长构件（50）的运动触发对注射的响应，例如可听和/或触觉注射完成指示。
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公开(公告)号：US11819668B2
公开(公告)日：2023-11-21
申请号：US17346886
申请日：2021-06-14
申请人： Owen Mumford Limited
发明人： Toby Cowe
CPC分类号： A61M5/31553 , A61M5/20 , A61M5/2033 , A61M5/24 , A61M5/31536 , A61M5/31551 , A61M5/315 , A61M5/3129 , A61M5/31548 , A61M5/31556 , A61M5/31558 , A61M5/31561 , A61M5/31575 , A61M5/31583 , A61M5/31585 , A61M2005/202 , A61M2005/2407 , A61M2005/2492 , A61M2005/3103 , A61M2205/581 , A61M2205/583
摘要： An injector apparatus includes a housing (101, 102) for a cartridge or syringe, a plunger (40) for cooperating in use with the cartridge or syringe to express successive doses, a dose setting arrangement (16, 20) to select a dose volume, and a drive mechanism (22, 24) releasable to advance the plunger in respective predetermined increments of magnitude to express the successive doses. The drive mechanism includes a drive spring (22) for imparting movement directly or indirectly to the plunger (40), and the dose setting arrangement includes a dose setting element (16) moveable in a dose setting routine to define a magnitude of an increment of movement of the plunger for a given dose. The drive mechanism further includes a clutch arrangement (56) operable during the dose setting routine to inhibit forward movement of the plunger and/or to isolate the dose setting element from the force of the drive spring.
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