摘要:
Compounds of the general formula (I) are useful as fungicides wherein Het is a 5- or 6-linked group of the formula (a) or (b), and the variables are as defined in the claims.
摘要:
Fungicidal compounds of the general formula (1): wherein X, Y and Z are independently H, halogen, C1-4 alkyl, halo(C1-4)alkyl, C2-4alkenyl, halo(C2-4)alkenyl, C24 alkynyl, halo(C2-4)alkynyl, C1-4 alkoxy, halo(C1-4)alkoxy, —S(O)n(C1-4)alkyl where n is 0, 1 or 2 and the alkyl group is optionally substituted with fluoro, —OS02(C1-4)alkyl where the alkyl group is optionally substituted with fluoro, cyano, nitro, C1-4 alkoxycarbonyl, —CONR′R″, —COR′, —NR′COR″ or —NR′COOR′″ where R′ and R″ are independently H or C1-4, alkyl and R′″ is C1-4 alkyl, provided that at least one of X and Z is other than H; R1 is C1-4alkyl, C2-4 alkenyl or C2-4 alkynyl in which the alkyl, alkenyl and alkynyl groups are optionally substituted on their terminal carbon atom with one, two or three halogen atoms, with a cyano group, with a C1-4 alkylcarbonyl group, with a C1-4 alkoxycarbonyl group or with a hydroxy group; R2 is H, C1-4 alkyl, C1-4 alkoxymethyl or benzyloxymethyl in which the phenyl ring of the benzyl moiety is optionally substituted with C1-4alkoxy; R3 and R4 are independently H, C1-3 alkyl, C2-3 alkenyl or C2-3 alkynyl provided that both are not H and that when both are other than H their combined total of carbon atoms does not exceed 4, or R3 and R4 join with the carbon atom to which they are attached to form a 3 or 4 membered carbocyclic ring optionally containing one 0, S or N atom and optionally substituted with halo or C1-4alkyl; and R5 is unsubstituted C3-4 alkyl, unsubstituted C3-6 cycloalkyl or C1-4 alkyl or C3-6 cycloalkyl in which the alkyl and cycloalkyl groups are substituted with halo, hydroxy, C1-6 alkoxy, cyano, C1-4 alkylcarbonyloxy, aminocarbonyloxy, mono- or di(C1-4)alkylaminocarbonyloxy, —S(O)″(C1-6)alkyl where n is 0, 1 or 2, triazolyl, tri(C1-4)alkylsilyloxy, optionally substituted phenoxy, optionally substituted thienyloxy, optionally substituted benzyloxy or optionally substituted thienyl-methoxy, in which the optionally substituted phenyl and thienyl rings of phenoxy, thienyloxy, benzyloxy and thienylmethoxy are optionally substituted with one, two or three substituents selected from halo, hydroxy, mercapto, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4alkoxy, C2-4 alkenyloxy, C2-4 alkynyloxy, halo(C1-4)alkyl, halo(C1-4)alkoxy, C1-4 alkylthio; halo(C1-4)alkylthio, hydroxy(C1-4)alkyl, C1-4 alkoxy(C1-4)alkyl, C3-6 cycloalkyl, C3-6 cycloalkyl(C1-4)alkyl, phenoxy, benzyloxy, benzoyloxy, cyano, isocyano, thiocyanato, isothiocyanato, nitro, —NR—R′, —NHCORm, —NHCONRmR″, —CONRmR″, —S02Rm, —OS02Rm, —CORM, —CR′═NR″ or —N═CRmR″, in which R′″ and R″ are independently hydrogen, CI-4 alkyl, halo(C1-4)alkyl, C1-4 alkoxy, halo(C1-4)alkoxy, C1-4alkylthio, C3-6 cycloalkyl, C3-6 cycloalkyl(C1-4)alkyl, phenyl or benzyl, the phenyl and benzyl groups being optionally substituted with halogen, C1-4alkyl or C1-4 alkoxy.
摘要:
Fungicidal compounds of the general formula (1), or the corresponding pyridine N-oxide, wherein X, Y, R1, R2, R3, R4 and R5 are as defined in the description.
摘要翻译:通式(1)的杀真菌化合物或相应的吡啶N-氧化物,其中X,Y,R 1,R 2,R 3, R 4,R 4和R 5如在说明书中所定义。
摘要:
The present invention also relates to carvedilol free base, carvedilol salts, anhydrous forms, or solvates thereof, corresponding pharmaceutical compositions or controlled release formulations, and delivery or dosing methods of carvedilol forms to the lower gastrointestingal tract or methods to treat cardiovascular diseases, which may include, but are not limited to hypertension, congestive heart failure, atherosclerosis, and angina. The present invention relates to controlled release formulations, which comprise various carvedilol forms, which may include, but are not limited to a carvedilol free base or corresponding carvedilol salts, anhydrous forms or solvates thereof.
摘要:
A compound of the general formula (I): ##STR1## wherein R is C.sub.2 -C.sub.4 alkenyl or C.sub.2 -C.sub.4 alkynyl, both optionally substituted by lower alkyl, halogen or trialkylsilyl; E is CN or CSNH.sub.2 ; and Y is C.sub.1 -C.sub.4 alkoxy, C.sub.3 -C.sub.4 alkenyloxy, C.sub.3 -C.sub.4 alkynyloxy, 1-pyrazolyl or 2-furyl. The compounds have fungicidal and plant growth regulating activity.