利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

58 条记录 (耗时 0.031 秒)

    Metabolically engineered microbial cell with an altered metabolite production
    21.
    发明授权
    Metabolically engineered microbial cell with an altered metabolite production 有权
    具有改变的代谢产物的代谢工程的微生物细胞

    公开(公告)号：US07018829B1

    公开(公告)日：2006-03-28

    申请号：US09743414

    申请日：1999-07-12

    申请人： Jens Nielsen ,  Torben Lauesgaard Nissen ,  Morten C. Kielland-Brandt

    发明人： Jens Nielsen ,  Torben Lauesgaard Nissen ,  Morten C. Kielland-Brandt

    IPC分类号： C12N1/16 ,  C12N1/19 ,  C12N15/81 ,  C12P7/06 ,  A01N63/02

    CPC分类号： C12N9/0036 ,  C12N9/0016 ,  C12N9/93 ,  C12P7/06 ,  Y02E50/17

    摘要： A recombinant microbial cell comprises at least one increased expressible enzyme activity controlling anabolic metabolism of ammonia as a nutrient source, the increased enzyme activity being an NADH-dependent activity catalysing the reaction (a) 2-oxoglutarate+NH3+NADH→glutamate+NAD or being an activity catalysing the reaction (b) 2-oxoglutarate+glutamine+NADH→2 glutamate+NAD or being an activity catalysing the reaction (c) glutamate+NH3+ATP→glutamine+ADP+Pi. The increased enzyme activity is encoded by a nucleic acid coding sequence linked to an expression signal not natively associated with the nucleic acid coding sequence and is increased as compared to the expression of the enzyme activity when the nucleic acid coding sequence is associated with its native expression signal.

    摘要翻译： 重组微生物细胞包含控制氨作为营养源的合成代谢的至少一种增加的可表达酶活性，增加的酶活性是催化反应的NADH依赖性活性（a）2-氧戊二酸盐+ NH 3 > NAD +>谷氨酸+ NAD或作为催化反应的活性（b）2-氧戊二酸+谷氨酰胺+ NADH->谷氨酸+ NAD或催化反应的活性（c）谷氨酸+ NH 3 SUB> + ATP->谷氨酰胺+ ADP + Pi。 增加的酶活性由与核酸编码序列本身不相关的表达信号连接的核酸编码序列编码，并且当核酸编码序列与其天然表达相关时与酶活性的表达相比增加 信号。

    Low-viscosity emulsions
    22.
    发明申请
    Low-viscosity emulsions 审中-公开
    低粘度乳液

    公开(公告)号：US20050238610A1

    公开(公告)日：2005-10-27

    申请号：US11040813

    申请日：2005-01-21

    申请人： Jens Nielsen ,  Thomas Raschke ,  Nadine Voigt

    发明人： Jens Nielsen ,  Thomas Raschke ,  Nadine Voigt

    IPC分类号： A61K8/06 ,  A61K8/39 ,  A61K8/86 ,  A61Q17/04 ,  A61Q19/00 ,  A61K7/075 ,  A61K7/08

    CPC分类号： A61K8/062 ,  A61K8/06 ,  A61K8/39 ,  A61K8/86 ,  A61Q17/04 ,  A61Q19/00

    摘要： Cosmetic and/or dermatological oil-in-water (O/W) emulsion with a viscosity of 100 to 1900 mPaS, containing a) one or more electrolytes in a concentration of 0.5 to 8% by weight, b) a thickener in a concentration of 0.05 to 1% by weight, and c) an emulsifier combination in a concentration of 0.5 to 6% by weight, which comprises polyethylene glycol stearate esters and at least one further emulsifier selected from polyoxyethylene cetylstearyl ethers and glyceryl stearate, wherein the weight percentages are based on the total weight of the emulsion.

    摘要翻译： 化妆品和/或皮肤病学油包水（O / W）乳液，其粘度为100至1900mPaS，含有a）一种或多种浓度为0.5至8重量％的电解质，b）浓度增稠剂 为0.05〜1重量％，c）浓度为0.5〜6重量％的乳化剂组合，其包含聚乙二醇硬脂酸酯和至少一种选自聚氧乙烯鲸蜡硬脂基醚和硬脂酸甘油酯的其它乳化剂，其中重量百分数 基于乳液的总重量。

    METHODS AND PRODUCTS FOR PRODUCTION OF WAX ESTERS
    23.
    发明申请
    METHODS AND PRODUCTS FOR PRODUCTION OF WAX ESTERS 审中-公开

    公开(公告)号：US20180237812A1

    公开(公告)日：2018-08-23

    申请号：US15927483

    申请日：2018-03-21

    申请人： Jens Nielsen ,  Shuobo Shi

    发明人： Jens Nielsen ,  Shuobo Shi

    IPC分类号： C12P7/64 ,  C12N9/10 ,  C12N15/81

    摘要： The present invention relates to the provision of genetically modified fungal cells, such as yeast cells with an improved ability for producing different fatty acids and specifically fatty acid ethyl esters (FAEE), the main components of biodiesel. An increased in fatty acid production, and hence in FAEE, is obtained in the first place by expressing different heterologous polypeptides in combination with the down-regulation, attenuation, deletion or over-expression of specially selected genes, wherein said genes encode enzymes involved in the fatty acids synthesizing pathway, fatty acid consuming pathways, carbohydrate biosynthesis pathways or enzyme acting as wax ester transporters or a combination thereof. The methods and products of the invention would allow large-scale production of FAEE with carbohydrates as the only externally-supplied substrate.

    EVACUATION SYSTEM
    24.
    发明申请
    EVACUATION SYSTEM 有权
    排气系统

    公开(公告)号：US20140283729A1

    公开(公告)日：2014-09-25

    申请号：US14127132

    申请日：2012-06-15

    申请人： Christian Ibsen ,  Søren Kristiansen ,  Jens Nielsen ,  Sinne Nielsen ,  Knud Søndertoft Pedersen

    发明人： Christian Ibsen ,  Søren Kristiansen ,  Jens Nielsen ,  Sinne Nielsen ,  Knud Søndertoft Pedersen

    IPC分类号： B63B23/40 ,  B63C9/02

    CPC分类号： B63B23/48 ,  B63B23/40 ,  B63C9/02 ,  B63C9/03 ,  B63C9/22 ,  B63C2009/035

    摘要： The present invention relates to an evacuation system (4) for a vessel (1) or offshore facility, comprising a storage unit (7) having a length, a width and a height defining a volume of the storage unit (7), the storage unit (7) in a storage situation being adapted to house one or more self-propelling, inflatable floatable units (5), the inflatable floatable units each having a capacity of more than 150 persons, and a deployment arrangement (8) having a displacement device, wherein a maximum height of the storage unit is 2.7 metres, and the displacement device is adapted to displace the one or more self-propelling, inflatable floatable units in a substantially horizontal and linear direction out of the storage unit (7) below the maximum height and subsequently lower the one or more self-propelling, inflatable floatable units (5) into the water in a substantially vertical direction.

    摘要翻译： 本发明涉及一种用于容器（1）或海上设施的抽空系统（4），其包括具有限定所述存储单元（7）的体积的长度，宽度和高度的存储单元（7），所述存储 存储状态下的单元（7）适于容纳一个或多个自推进的可充气可浮动单元（5），每个具有超过150人的容量的可膨胀的可浮动单元和具有位移的展开装置（8） 装置，其中所述存储单元的最大高度为2.7米，并且所述位移装置适于将基本上水平和线性方向上的所述一个或多个自推进的，可充气的可浮动单元移出所述存储单元（7）的下方 并且随后将一个或多个自推进的，可充气的可漂浮单元（5）沿基本垂直的方向下降到水中。

    Oxaloacetate hydrolase deficient fungal host cells
    27.
    发明授权
    Oxaloacetate hydrolase deficient fungal host cells 有权
    草酰乙酸水解酶缺陷型真菌宿主细胞

    公开(公告)号：US07919275B2

    公开(公告)日：2011-04-05

    申请号：US12719648

    申请日：2010-03-08

    申请人： Carsten Mailand Hjort ,  Henrik Pedersen ,  Jens Nielsen

    发明人： Carsten Mailand Hjort ,  Henrik Pedersen ,  Jens Nielsen

    IPC分类号： C12N1/15 ,  C12P21/00

    CPC分类号： C12Q1/6895 ,  C12N9/14

    摘要： An isolated mutant host cell produced by disrupting or deleting, in a parent cell, a nucleic acid sequence encoding an oxaloacetate hydrolase, or a promoter thereof, which results in the mutant cell producing less of the oxaloacetate hydrolase than the parent cell is disclosed. The disclosure also relates to recombinant methods for producing the products such as polypeptides.

    摘要翻译： 公开了一种分离的突变宿主细胞，其通过在母体细胞中破坏或缺失编码草酰乙酸水解酶的核酸序列或其启动子，导致突变体细胞产生比母细胞少的草酰乙酸酯水解酶。 本公开还涉及用于生产诸如多肽的产物的重组方法。

    ESCAPE SYSTEM WITH SELF-ADJUSTING LENGTH
    28.
    发明申请
    ESCAPE SYSTEM WITH SELF-ADJUSTING LENGTH 有权
    具有自调节长度的ESCAPE系统

    公开(公告)号：US20100051383A1

    公开(公告)日：2010-03-04

    申请号：US12444132

    申请日：2007-10-04

    申请人： Jens Nielsen

    发明人： Jens Nielsen

    IPC分类号： A62B1/20

    CPC分类号： A62B1/20

    摘要： An escape system (1) for evacuation is disclosed including a chute (2) comprising a succession of linked and spaced apart shaping sections (7), the succession including a number of shaping sections being connected by elastic cords (9) and linking successive shaping sections in a direction corresponding to a longitudinal axis (18) of the succession of shaping sections, and at least one tunnel-like device (6) being adapted to enable a person (16) who is being evacuated to move from a first position (3) to a second position (4) through the tunnel-like device, and wherein the chute (2) is arranged to have a self adjusting length (20, 22) and hereby operable at least two relative different chute lengths (20, 22) when the chute (2) has been launched and the chute is hanging substantially vertically from the higher position to the lower position, and the escape system comprises length limiting means (32, 36, 38) for changing between operation modes (24, 26) between the at least two relative different chute lengths (20, 22).

    摘要翻译： 公开了一种用于抽真空的逃逸系统（1），包括一系列连接和间隔开的整形部分（7）的滑槽（2），该连续件包括多个通过弹性帘线（9）连接的成形部分， 在与所述连续成形部分的纵向轴线（18）相对应的方向上的部分，以及至少一个隧道状装置（6），其适于使得被疏散的人（16）能够从第一位置移动 3）通过隧道状装置到达第二位置（4），并且其中滑槽（2）被布置成具有自调节长度（20,22），并且因此可操作至少两个相对不同的斜槽长度（20,22） ），当斜槽（2）已经被启动并且滑槽从较高位置垂直悬挂到下部位置时，并且逃逸系统包括用于在操作模式（24,26）之间改变的长度限制装置（32,36,38） ）在至少两个相对d之间 不同的滑槽长度（20,22）。