公开(公告)号：US20080065013A1

公开(公告)日：2008-03-13

申请号：US11854894

申请日：2007-09-13

Applicant: Richard Goodin

Inventor： Richard Goodin

IPC: A61M25/10

CPC classification number: A61M25/10 ,  A61M25/0052 ,  A61M25/104 ,  A61M2025/1093

Abstract: A balloon catheter may include an elongate shaft and a shaft lumen extending through the elongate shaft to a distal end thereof A balloon may be disposed about a distal region of the elongate shaft while a coil may be disposed within the balloon. A polymer coating may be disposed on an interior of the balloon. The coil may be formed of a coil wire that is polymer coated prior to winding the coil. The catheter may be either OTW or SOE.

Abstract translation: 球囊导管可以包括细长轴和延伸穿过细长轴到其远端的轴腔。气囊可以围绕细长轴的远侧区域设置，而线圈可以设置在气囊内。 聚合物涂层可以设置在气囊的内部。 线圈可以由在卷绕线圈之前聚合物涂覆的线圈线形成。 导管可以是OTW或SOE。

公开(公告)号：US20070135763A1

公开(公告)日：2007-06-14

申请号：US11301195

申请日：2005-12-12

Applicant: Frank Musbach ,  Tracee Eidenschink ,  Richard Gunderson ,  Richard Olson ,  Daniel Tomaschko ,  Richard Goodin ,  Todd Turnlund ,  Jason Lenz

Inventor： Frank Musbach ,  Tracee Eidenschink ,  Richard Gunderson ,  Richard Olson ,  Daniel Tomaschko ,  Richard Goodin ,  Todd Turnlund ,  Jason Lenz

IPC: A61M29/00

CPC classification number: A61M25/0054 ,  A61M25/0029 ,  A61M25/0032 ,  A61M25/0138 ,  A61M25/10

Abstract: Medical devices that include micromachined hypotubes or that have themselves been micromachined can provide advantages in flexibility, strength and other desirable properties. Examples of such medical devices may include catheters such as guide catheters and balloon catheters. Such devices may also include dual shaft medical devices in which an outer shaft is reversibly lockable onto an inner shaft.

Abstract translation: 包括微加工海波管或本身已经被微加工的医疗装置可以提供灵活性，强度和其它所需性质的优点。 这种医疗装置的示例可以包括导管，例如导向导管和球囊导管。 这样的装置还可以包括双轴医疗装置，其中外轴可逆地锁定到内轴上。

公开(公告)号：US20060141521A1

公开(公告)日：2006-06-29

申请号：US11345252

申请日：2006-02-01

Applicant: Richard Willson ,  Richard Goodin

Inventor： Richard Willson ,  Richard Goodin

IPC: C12Q1/68

CPC classification number: C12Q1/6844 ,  C12Q2521/107 ,  C12Q2527/125

Abstract: RNA, preferably messenger RNA, is purified by use of selective precipitation, preferably by addition of compaction agents. Also included is a scaleable method for the liquid-phase separation of DNA from RNA. RNA may also be recovered by fractional precipitation according to the invention. We have discovered that specific classes of compounds are unexpectedly potent in causing selective precipitation of DNA away from RNA, at low concentrations and in the presence of relatively elevated ionic strength. Modification of the selective removal of DNA can also remove both RNA and DNA, leaving behind a mixture which is advantageous for the further purification of, e.g., proteins. Additional aspects of the invention include mini-preps, preferably of RNA or of plasmid and chromosomal DNA to obtain sequenceable and restriction digestible DNA in high yields in multiple simultaneous procedures. Still further aspects disclose enhanced stripping of the compaction agent by a stripping method comprising high salt addition and pH shift, and combinations of these techniques. RNA Abstract Additionally, a new approach to the isolation of RNA from bacterial lysates employs selective precipitation by compaction agents. The above techniques can be enhanced by use of phase transfer catalysts (PTCs), most preferably selected polyamines of U.S. Pat. No. 6,617,108 polyamines which are quaternary compounds. (The use of PTCs in biotechnical processes is not evident in the literature, see e.g. www./ptorganics.com as of 27 Jan. 2005.)

Abstract translation: 通过使用选择性沉淀，优选通过加入压实剂来纯化RNA，优选信使RNA。 还包括用于从RNA液相分离DNA的可缩放方法。 根据本发明也可以通过分级沉淀来回收RNA。 我们已经发现，特定类别的化合物意外地在低浓度下和在相对提高的离子强度存在下引起DNA远离RNA的选择性沉淀。 选择性去除DNA的修饰也可以除去RNA和DNA，留下混合物，这有利于进一步纯化例如蛋白质。 本发明的另外的方面包括优选RNA或微质和染色体DNA的微型制品，以在多个同时操作的程序中以高产率获得可序列的和限制性可消化的DNA。 另外的方面公开了通过包括高盐添加和pH漂移的剥离方法以及这些技术的组合增强了压实剂的剥离。 RNA摘要另外，从细菌裂解物中分离RNA的新方法采用压实剂的选择性沉淀。 上述技术可以通过使用相转移催化剂（PTC），最优选选自美国专利No. 作为季铵化合物的6,617,108多胺。 （在生物技术过程中使用PTC并不明显，参见例如2005年1月27日的www./ptorganics.com）

公开(公告)号：US20050227087A1

公开(公告)日：2005-10-13

申请号：US10822581

申请日：2004-04-12

Applicant: Robert Burgmeier ,  Richard Goodin ,  Joseph Delaney

Inventor： Robert Burgmeier ,  Richard Goodin ,  Joseph Delaney

IPC: B32B7/12 ,  B32B27/08 ,  B32B27/32 ,  B32B27/34 ,  B32B27/36 ,  B65D1/00 ,  B32B27/00

CPC classification number: B32B7/12 ,  B32B27/08 ,  B32B27/34 ,  B32B27/36 ,  B32B2367/00 ,  B32B2377/00 ,  Y10T428/31551 ,  Y10T428/31565 ,  Y10T428/31587 ,  Y10T428/31725 ,  Y10T428/31786

Abstract: A coextrusion employing a tie layer between two layers of different polymer materials. The tie layer is formed in the extrusion melt of a composition comprising one of the two polymer materials and a coupling agent that includes functional groups that are reactive at least with functional groups on the second polymer. The coupling agent may be incorporated into the tie layer material in amounts above 5% by weight.

Abstract translation: 使用两层不同聚合物材料之间的粘结层的共挤出。 粘结层在包含两种聚合物材料之一的组合物的挤出熔体中形成，并且偶联剂包括至少与第二聚合物上的官能团反应的官能团。 偶联剂可以以5重量％以上的量掺入粘结层材料中。

公开(公告)号：US20050119616A1

公开(公告)日：2005-06-02

申请号：US11026295

申请日：2004-12-30

Applicant: Richard Goodin ,  Katherine Prindle

Inventor： Richard Goodin ,  Katherine Prindle

IPC: A61M25/00 ,  B29C65/00 ,  B29C65/02 ,  A61M29/00

CPC classification number: A61M25/1034 ,  A61M25/0009 ,  A61M25/0014 ,  B29C65/02 ,  B29C65/16 ,  B29C66/03241 ,  B29C66/1122 ,  B29C66/534 ,  B29C66/63 ,  B29C66/71 ,  B29C66/73715 ,  B29C66/82 ,  B29L2031/7542 ,  B29L2031/7543 ,  Y10T156/10

Abstract: A catheter comprises a first component and a second component. The first component has a first outer diameter and the second component has a second outer diameter. At least a portion of the first component being bonded to at least a portion of the second component. When the at least a portion of the first component is bonded to the at least a portion of the second component the first outer diameter is substantially equal to the second outer diameter. A heat shrink material being utilized to bond the at least a portion of the first component to the at least a portion of the second component.

Abstract translation: 导管包括第一部件和第二部件。 第一部件具有第一外径，第二部件具有第二外径。 第一组分的至少一部分被结合到第二组分的至少一部分。 当第一部件的至少一部分结合到第二部件的至少一部分时，第一外直径基本上等于第二外径。 用于将第一组分的至少一部分结合至第二组分的至少一部分的热收缩材料。