利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

53 条记录 (耗时 0.035 秒)

    Nanomagnetic detector array for biomolecular recognition
    3.
    发明授权
    Nanomagnetic detector array for biomolecular recognition 有权
    用于生物分子识别的纳米磁检测器阵列

    公开(公告)号：US08456157B2

    公开(公告)日：2013-06-04

    申请号：US11996945

    申请日：2006-07-26

    申请人： Dmitri Litvinov ,  Richard Willson

    发明人： Dmitri Litvinov ,  Richard Willson

    IPC分类号： G01R33/00

    CPC分类号： G01N33/54373

    摘要： A biomolecular sensor system includes an array of magnetoresistive nanosensors designed for sensing biomolecule-conjugated superparamagnetic nanoparticles. Materials and geometry of each sensor element are designed for optimized sensitivity. The system includes magnetic field generators to apply forces to superparamagnetic nanoparticles for 1) nanoparticle manipulation, 2) sensor magnetic biasing, 3) magnetic pull-off measurement for differentiation against non-specific association, and 4) removal of all particles from the sensor array surface.

    摘要翻译： 生物分子传感器系统包括设计用于感测生物分子结合的超顺磁性纳米粒子的磁阻纳米传感器阵列。 每个传感器元件的材料和几何形状设计用于优化灵敏度。 该系统包括磁场发生器，以对超顺磁纳米颗粒施加力量1）纳米颗粒操纵，2）传感器磁偏置，3）用于区分非特异性缔合的磁性拉脱测量，以及4）从传感器阵列中去除所有颗粒 表面。

    Force Mediated Assays
    4.
    发明申请
    Force Mediated Assays 审中-公开
    强制调解

    公开(公告)号：US20120288852A1

    公开(公告)日：2012-11-15

    申请号：US13522319

    申请日：2011-01-15

    申请人： Richard Willson ,  Paul Ruchhoeft

    发明人： Richard Willson ,  Paul Ruchhoeft

    IPC分类号： G01N21/75 ,  G01N21/55 ,  G01N21/65 ,  G01N21/64 ,  G01N21/76 ,  B82Y15/00

    CPC分类号： G01N33/54306 ,  G01N15/10 ,  Y10T436/143333

    摘要： A sensitive and specific method of detecting chemical species, viruses and microorganisms is presented to improve performance of molecular-recognition-based assays utilizing particles decorated with molecular recognition agents such as antibodies and DNA probes, and observing analyte-dependent changes in the response of the particles to forces such as magnetic or gravitational forces or Brownian thermal fluctuations.

    摘要翻译： 提出了一种检测化学物质，病毒和微生物的敏感和具体方法，以提高利用分子识别剂如抗体和DNA探针装饰的颗粒的基于分子识别的测定的性能，并观察分子识别的测定反应中的分析物依赖性变化 颗粒到力或磁力或重力或布朗热波动。

    Semiconductor Device Crack-Deflecting Structure and Method
    8.
    发明申请
    Semiconductor Device Crack-Deflecting Structure and Method 审中-公开
    半导体器件裂纹偏转结构与方法

    公开(公告)号：US20090166810A1

    公开(公告)日：2009-07-02

    申请号：US11965849

    申请日：2007-12-28

    申请人： Daniel Joseph Stillman ,  Charles Anthony Odegard ,  Gregory Barton Hotchkiss ,  Richard Willson Arnold

    发明人： Daniel Joseph Stillman ,  Charles Anthony Odegard ,  Gregory Barton Hotchkiss ,  Richard Willson Arnold

    IPC分类号： H01L23/544 ,  H01L21/71

    CPC分类号： H01L23/562 ,  H01L21/78 ,  H01L23/585 ,  H01L2924/0002 ,  H01L2924/00

    摘要： The invention relates to microelectronic semiconductor devices, and to mass-production of the same on semiconductor wafers with novel crack-deflecting structures and methods. According to the invention, a semiconductor device includes an active circuit area surrounded by an inactive area and circumscribed with a bulwark having a crack-deflecting face oriented toward the periphery of the device. Embodiments of the invention are disclosed, in which a semiconductor device, or multiple devices on a wafer, include bulwarks having series of minor arcs with their chords oriented toward the peripheries of the devices. Additional embodiments of the invention described include bulwarks having series of right angles oriented toward the peripheries of the devices. Examples of the invention also include preferred embodiments wherein the bulwarks further comprise series of discrete pickets, parallel bulwarks, and bulwarks in combination with scribe seals.

    摘要翻译： 本发明涉及微电子半导体器件，并且通过新的裂纹偏转结构和方法在半导体晶片上批量生产它们。 根据本发明，半导体器件包括由非活性区域包围的有源电路区域，并且与具有朝向器件周边定向的裂纹偏转面的舷墙外接。 公开了本发明的实施例，其中半导体器件或晶片上的多个器件包括具有一系列小弧的舷墙，其小弦弧朝向器件的周边方向。 所描述的本发明的另外的实施例包括具有朝向装置的周边的一系列直角的舷墙。 本发明的实例还包括优选实施例，其中舷墙还包括一系列分立的桩，平行的舷墙和舷墙以及划线密封。