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公开(公告)号：US08313484B2
公开(公告)日：2012-11-20
申请号：US11254951
申请日：2005-10-20
Applicant: Stuart D Edwards , David S Utley
Inventor： Stuart D Edwards , David S Utley
CPC classification number: A61B18/1492 , A61B2018/00553
Abstract: A method of forming a composite lesion pattern in a tissue region at or near a sphincter comprising providing a catheter having a plurality of energy delivery devices coupled to the catheter. The catheter is introduced at least partially into the sphincter. Energy is delivered from the energy delivery devices to produce the composite lesion pattern. The composite lesion pattern comprises a radial distribution of lesions about the tissue region and a longitudinal distribution of lesions along the tissue region.
Abstract translation: 在括约肌处或附近在组织区域中形成复合损伤图案的方法，包括提供具有耦合到导管的多个能量输送装置的导管。 将导管至少部分地引入括约肌。 能量从能量输送装置输送以产生复合损伤模式。 复合损伤图案包括围绕组织区域的损伤的径向分布和沿着组织区域的损伤的纵向分布。
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公开(公告)号：US08152803B2
公开(公告)日：2012-04-10
申请号：US11651750
申请日：2007-01-10
Applicant: Stuart D Edwards , David S Utley , Ronald G Lax
Inventor： Stuart D Edwards , David S Utley , Ronald G Lax
IPC: A61B18/14
CPC classification number: A61B5/04884 , A61B18/1477 , A61B18/1485 , A61B90/39 , A61B2018/00553 , A61B2018/00738 , A61B2018/046 , A61B2090/3925 , A61B2560/0242
Abstract: An apparatus to treat a sphincter has a support member. A sphincter electropotential mapping device includes a mapping electrode. The sphincter electropotential mapping device is coupled to the support member and configured to detect aberrant myoelectric activity of the sphincter.
Abstract translation: 治疗括约肌的装置具有支撑构件。 括约肌电位映射装置包括映射电极。 括约肌电位映射设备耦合到支撑构件并且被配置为检测括约肌的异常肌电活动。
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公开(公告)号：US07449020B2
公开(公告)日：2008-11-11
申请号：US11079697
申请日：2005-03-14
Applicant: Stuart D Edwards , David S Utley , Ronald G Lax , John Gaiser
Inventor： Stuart D Edwards , David S Utley , Ronald G Lax , John Gaiser
IPC: A61B18/18
CPC classification number: A61B18/1492 , A61B18/1206 , A61B18/1477 , A61B18/18 , A61B2018/00011 , A61B2018/00029 , A61B2018/00047 , A61B2018/00214 , A61B2018/0022 , A61B2018/00494 , A61B2018/00553 , A61B2018/00666 , A61B2018/00678 , A61B2018/00684 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00744 , A61B2018/00791 , A61B2018/00875 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1425 , A61B2218/002
Abstract: A method for treating a sphincter provides a polymer material having a liquid state. The method also provides a catheter having a distal end, a tissue piercing device carried by the distal end, and an energy delivery device coupled to the tissue piercing device. The tissue piercing device has a lumen. The method introduces the catheter into an esophagus and pierces an exterior sphincter tissue surface within with the tissue piercing device. The method advances the tissue piercing device into an interior sphincter tissue site and conveys the polymer material while in a liquid state through the lumen into the interior sphincter tissue site. The method delivers energy to the tissue piercing device to transform the polymer material into a less liquid state within the interior sphincter tissue site, to thereby remodel the sphincter.
Abstract translation: 用于治疗括约肌的方法提供具有液体状态的聚合物材料。 该方法还提供了具有远端的导管，由远端承载的组织刺穿装置，以及耦合到组织刺穿装置的能量输送装置。 组织穿刺装置具有内腔。 该方法将导管引入食道并刺穿组织穿刺装置内的外括约肌组织表面。 该方法使组织穿刺装置进入内部括约肌组织部位，并将液体状态下的聚合物材料通过内腔输送到内括约肌组织部位。 该方法将能量传递到组织刺穿装置，以将聚合物材料转变成内部括约肌组织部位内的较少液体状态，从而改变括约肌。
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公开(公告)号：US06971395B2
公开(公告)日：2005-12-06
申请号：US10428458
申请日：2003-05-02
Applicant: Stuart D Edwards , David S Utley
Inventor： Stuart D Edwards , David S Utley
CPC classification number: A61B18/1492 , A61B2018/00553
Abstract: A method of forming a composite lesion pattern in a tissue region at or near a sphincter comprising providing a catheter having a plurality of energy delivery devices coupled to the catheter. The catheter is introduced at least partially into the sphincter. Energy is delivered from the energy delivery devices to produce the composite lesion pattern. The composite lesion pattern comprises a radial distribution of lesions about the tissue region and a longitudinal distribution of lesions along the tissue region.
Abstract translation: 在括约肌处或附近在组织区域中形成复合损伤图案的方法，包括提供具有耦合到导管的多个能量输送装置的导管。 将导管至少部分地引入括约肌。 能量从能量输送装置输送以产生复合损伤模式。 复合损伤图案包括围绕组织区域的损伤的径向分布和沿着组织区域的损伤的纵向分布。
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公开(公告)号：US06872206B2
公开(公告)日：2005-03-29
申请号：US10247153
申请日：2002-09-19
Applicant: Stuart D Edwards , John Gaiser , David S Utley , Scott H West , Jay Qin
Inventor： Stuart D Edwards , John Gaiser , David S Utley , Scott H West , Jay Qin
CPC classification number: A61B18/1492 , A61B18/12 , A61B18/1206 , A61B18/1477 , A61B18/1485 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
Abstract: Methods treat a tissue region. In one arrangement, the methods deploy an electrode on a support structure in a tissue region at or near the cardia of the stomach. In one embodiment, the support structure has a proximal region and a distal region. The proximal region is enlarged in comparison to the distal region, and the electrode is carried by the enlarged proximal surface. The methods advance the electrode in a path to penetrate the tissue region and couple the electrode to a source of radio frequency energy to ohmically heat tissue and create a lesion in the tissue region.
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Patent Agency Ranking
公开(公告)号：US06712814B2
公开(公告)日：2004-03-30
申请号：US09973467
申请日：2001-10-09
Applicant: Stuart D Edwards , David S Utley
Inventor： Stuart D Edwards , David S Utley
IPC: A61B1818
CPC classification number: A61B5/04884 , A61B5/01 , A61B5/0535 , A61B8/00 , A61B18/00 , A61B18/1206 , A61B18/1477 , A61B18/148 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00022 , A61B2017/00084 , A61B2017/00106 , A61B2017/003 , A61B2017/00867 , A61B2017/22062 , A61B2017/22072 , A61B2017/4216 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00065 , A61B2018/00077 , A61B2018/00083 , A61B2018/00113 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00232 , A61B2018/00267 , A61B2018/00291 , A61B2018/00494 , A61B2018/00553 , A61B2018/00559 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00738 , A61B2018/00744 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00827 , A61B2018/00839 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/0262 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1425 , A61B2018/1467 , A61B2018/1472 , A61B2090/3614 , A61B2090/3782 , A61B2218/002 , A61F7/12 , A61M3/0279 , A61M16/0438 , A61M16/0481 , A61M25/1002 , A61M2025/1052 , A61M2025/1086 , A61N1/056 , A61N1/06 , A61N1/08 , A61N1/40 , C08L2201/12
Abstract: A method of treating a sphincter that provides an expandable basket structure with a first energy delivery device. The basket structure is introduced in a sphincter. The first energy delivery device is advanced from the basket structure into an interior of the sphincter. Sufficient energy is delivered from the first energy delivery device to create a desired tissue effect in the sphincter. Thereafter, the basket structure is removed from the sphincter.
Abstract translation: 一种治疗括约肌的方法，所述括约肌提供具有第一能量递送装置的可扩张篮结构。 篮子结构被引入括约肌。 第一能量输送装置从篮状结构进入括约肌的内部。 从第一能量递送装置输送足够的能量以在括约肌中产生期望的组织效应。 此后，将括号结构从括约肌中取出。
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公开(公告)号：US06562034B2
公开(公告)日：2003-05-13
申请号：US10046637
申请日：2002-01-14
Applicant: Stuart D Edwards , John Gaiser , David S Utley , Scott West , Jay Qin
Inventor： Stuart D Edwards , John Gaiser , David S Utley , Scott West , Jay Qin
IPC: A61B1818
CPC classification number: A61B18/1485 , A61B18/1477 , A61B18/1492 , A61B2017/00867 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00553 , A61B2018/00738 , A61B2018/046 , A61B2018/1425 , A61B2090/036 , C08L2201/12
Abstract: Improved electrode assemblies for treating a tissue region at or near a sphincter comprise a support structure and an electrode carried by the support structure for advancement in a path to penetrate the tissue region. In one arrangement, the electrode has a non-cylindrical cross section selected to resist deflection when advanced to penetrate the tissue region. In another arrangement, the electrode includes a tissue stop to resist tissue penetration beyond a selected depth. In another arrangement, the electrode includes a proximal portion formed from a first material and a distal tissue penetrating portion formed of a second material different than the first material. The first material can comprise, e.g., stainless steel, and the second material can comprise, e.g., nickel titanium.
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28.发明授权公开(公告)号：US06423058B1
公开(公告)日：2002-07-23
申请号：US09304770
申请日：1999-05-04
Applicant: Stuart D Edwards , John Gaiser , David S Utley , Scott West , Jay Qin
Inventor： Stuart D Edwards , John Gaiser , David S Utley , Scott West , Jay Qin
IPC: A61B1818
CPC classification number: A61B18/1206 , A61B18/12 , A61B18/1477 , A61B18/1485 , A61B18/1492 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
Abstract: Assemblies for treating a tissue region at or near a sphincter have a support structure with a distal end and an electrode carried by the support structure for contact with the tissue region. A lumen in the support structure accommodates passage of a body through the support structure and beyond the distal end of the support structure. The body can comprise a guide wire to guide deployment of the support structure, or an endoscope to permit visualization of the support structure from beyond the distal end of the support structure.
Abstract translation: 用于治疗括约肌处或附近的组织区域的组件具有支撑结构，其具有远端和由支撑结构承载的用于与组织区域接触的电极。 支撑结构中的内腔容纳主体通过支撑结构并超出支撑结构的远端的通道。 主体可以包括引导线以引导支撑结构的展开，或内窥镜，以允许从支撑结构的远端超出支撑结构的可视化。
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公开(公告)号：US07648500B2
公开(公告)日：2010-01-19
申请号：US11175471
申请日：2005-07-06
Applicant: Stuart D Edwards , David Utley , Ronald G Lax , Theodore R Kucklick , Peter H Muller
Inventor： Stuart D Edwards , David Utley , Ronald G Lax , Theodore R Kucklick , Peter H Muller
CPC classification number: A61B18/14 , A61B17/32 , A61B18/1477 , A61B18/1492 , A61B18/1815 , A61B2018/00011 , A61B2018/00029 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00494 , A61B2018/00553 , A61B2018/00577 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00791 , A61B2018/00875 , A61B2018/00916 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1472 , A61B2018/183 , A61B2090/3614 , A61B2090/3782
Abstract: A sphincter treatment apparatus includes an energy delivery device introduction member including a proximal end with a first radius of curvature and a distal end with a second radius of curvature. The introduction member is configured to be introduced into the sphincter in a non-deployed state and to be expanded to a deployed state to at least partially expand the sphincter or an adjoining structure. An energy delivery device is coupled to the introduction member. A retainer member is coupled to the energy delivery device introduction member and configured to controllably position the introduction member in an orifice of the sphincter.
Abstract translation: 括约肌治疗装置包括能量输送装置导入构件，其包括具有第一曲率半径的近端和具有第二曲率半径的远端。 引入构件被配置为以非展开状态引入括约肌并且被扩展到展开状态以至少部分地扩展括约肌或相邻结构。 能量输送装置联接到引入构件。 保持器构件联接到能量输送装置引入构件并构造成将引导构件可控地定位在括约肌的孔中。
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公开(公告)号：US06315776B1
公开(公告)日：2001-11-13
申请号：US09338737
申请日：1999-06-23
Applicant: Stuart D Edwards , Kee S Lee , James Baker , Bruno Strul
Inventor： Stuart D Edwards , Kee S Lee , James Baker , Bruno Strul
IPC: A61B1818
CPC classification number: A61B18/1477 , A61B17/32 , A61B18/1206 , A61B18/148 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00084 , A61B2017/00106 , A61B2017/003 , A61B2017/22061 , A61B2017/4216 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00065 , A61B2018/00077 , A61B2018/00083 , A61B2018/00113 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00494 , A61B2018/00553 , A61B2018/00559 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00744 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00827 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/0262 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1425 , A61B2018/1467 , A61B2018/1472 , A61B2018/183 , A61B2090/3614 , A61B2090/3782 , A61B2218/002 , A61M3/0279 , A61M16/0481 , A61M25/1002 , A61M2025/105 , A61M2025/1052 , A61M2025/1086 , A61N1/056 , A61N1/06 , A61N1/08 , A61N1/40
Abstract: An ablation apparatus has an expandable member that is inserted into an organ of a body and ablates all or a selected portion of the inner layer of the organ. Electrolytic solution fills the expandable member, and the expandable member includes a plurality of apertures from which electrolytic solution flows from the expandable member. First and second fluid conduits, which can be first and second conforming members, are in a surrounding relationship to the expandable member. The second conforming member, including a conductive surface, is made of a material that provides substantial conformity between the conductive surface and a shape of the inner layer of the organ. A plurality of electrodes is positioned between the two conforming members. The expandable member serves as an insulator to RF energy. Each electrode includes an insulator formed on a surface of the electrode positioned adjacent to the second conforming member. The combination of sandwiching the electrodes between the two conforming members, and the use of two insulators, one on the electrode and the other on the expandable member, provides selectable ablation of the inner layer of the organ. A feedback device is included and is responsive to a detected characteristic of the inner layer. The feedback device provides a controlled delivery of RF energy to the electrodes.
Abstract translation: 消融装置具有插入到身体的器官中并且消融器官的内层的全部或选定部分的可扩张构件。 电解液填充可膨胀构件，并且可膨胀构件包括多个孔，电解溶液从该孔从可膨胀构件流出。 可以是第一和第二顺应构件的第一和第二流体管道与可膨胀构件处于环境关系。 包括导电表面的第二适形构件由在导电表面和器官内层的形状之间提供实质一致性的材料制成。 多个电极位于两个构件之间。 可扩展构件用作RF能量的绝缘体。 每个电极包括形成在电极的表面上的绝缘体，所述绝缘体位于邻近第二顺应构件的位置。 将电极夹在两个相容构件之间的组合以及使用两个绝缘体，一个在电极上，另一个在可扩张构件上，提供器官内层的可选消融。 包括反馈装置并响应于内层的检测特性。 反馈装置提供对电极的RF能量的受控输送。
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