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26 条记录 (耗时 0.022 秒)

    Polymer film for wrapping a stent structure
    21.
    发明授权
    Polymer film for wrapping a stent structure 失效
    用于包裹支架结构的聚合物膜

    公开(公告)号：US5637113A

    公开(公告)日：1997-06-10

    申请号：US355402

    申请日：1994-12-13

    申请人： Joseph M. Tartaglia ,  Joseph P. Loeffler ,  Todd H. Turnlund

    发明人： Joseph M. Tartaglia ,  Joseph P. Loeffler ,  Todd H. Turnlund

    IPC分类号： A61M31/00 ,  A61F2/00 ,  A61F2/82 ,  A61F2/92 ,  A61L27/00 ,  A61L31/00 ,  A61F2/06

    CPC分类号： A61F2/82 ,  A61F2/07 ,  A61F2/92 ,  A61F2/915 ,  A61F2002/075 ,  A61F2220/005 ,  A61F2250/0067

    摘要： The drug loaded stent includes an expandable stent structural member, and a planar sheet of polymeric material attached to the outside of the expandable stent structural member. The polymeric material is preferably bioabsorbable, and loaded or coated with a therapeutic agent or drug to reduce or prevent restenosis in the vessel being treated. The polymer material can be attached to the metal stent at one or more points, and wrapped in a coil around the stent in an unexpanded state, to uncoil and expand in diameter to substantially match the expanded diameter of the metal stent; or can be wrapped tightly around the stent structural member and attached to itself, to stretch radially when the stent structural member is expanded. In another currently preferred embodiment, a combination of a stent structural member and a polymeric film wrapping can be provided with a coating of lubricious material. The lubricious material can be polyethylene oxide, polyethylene glycol, polyethylene acetate, polyvinyl pyrrolidone, polyvinyl alcohol, polyacrylamide, hydrophilic soft segment urethanes, some natural gums, polyanhydrides or other similar hydrophilic polymers, and combinations thereof. The layer of lubricious material protects the stent from the guide or the body lumen in which the stent is inserted by providing a low friction surface over the stent.

    摘要翻译： 药物负载支架包括可扩张的支架结构构件和附接到可扩张支架结构构件的外侧的聚合物材料的平面片。 聚合物材料优选是生物可吸收的，并且加载或涂覆有治疗剂或药物以减少或预防待治疗血管中的再狭窄。 聚合物材料可以以一个或多个点附着到金属支架上，并且以未膨胀的状态包裹在支架周围的线圈中，以直径展开和膨胀以与金属支架的扩张直径基本匹配; 或者可以紧紧地包裹在支架结构构件上并且附接到其自身，以在支架结构构件膨胀时径向拉伸。 在另一个目前优选的实施方案中，支架结构构件和聚合物膜包裹物的组合可以提供有润滑材料的涂层。 润滑材料可以是聚环氧乙烷，聚乙二醇，聚乙酸乙烯酯，聚乙烯吡咯烷酮，聚乙烯醇，聚丙烯酰胺，亲水性软链段聚氨酯，一些天然树胶，聚酐或其它类似的亲水聚合物，及其组合。 光滑材料层通过在支架上提供低摩擦表面来保护支架免于插入支架的引导件或体腔。

    Biodegradable mesh and film stent
    22.
    发明授权
    Biodegradable mesh and film stent 失效
    可生物降解的网膜和薄膜支架

    公开(公告)号：US5629077A

    公开(公告)日：1997-05-13

    申请号：US266964

    申请日：1994-06-27

    申请人： Todd H. Turnlund ,  Robert P. Eury

    发明人： Todd H. Turnlund ,  Robert P. Eury

    IPC分类号： A61F2/00 ,  A61F2/02 ,  A61F2/82 ,  A61F2/92 ,  A61L31/06 ,  A61L31/14 ,  B32B7/00

    CPC分类号： A61F2/82 ,  A61F2/93 ,  A61L31/06 ,  A61L31/148 ,  B32B37/04 ,  A61F2/0077 ,  A61F2/07 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2210/0004 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2240/001 ,  A61F2250/0067 ,  B32B2367/00 ,  Y10S623/90 ,  Y10T156/1038 ,  Y10T428/1369 ,  Y10T442/164

    摘要： The biodegradable mesh and film stent for use in blood vessels is formed of a sheet of a composite mesh material formed of biodegradable high strength polymer fibers bonded together with a second biodegradable adhesive polymer, and laminated on at least one side with a thin film of a third biodegradable polymer. The biodegradable mesh and film material is formed as a sheet and cut in a shape that can be used as a stent, such as a "belt-buckle" type shape, the ends of which can be joined in a contractible, expandable loop. In the method of making the biodegradable composite mesh and film stent, the composite mesh is preferably formed from a weave formed of high strength biodegradable polymeric fibers, and a plurality of low temperature melting biodegradable polymeric fibers. In an alternate embodiment, the high strength fibers are commingled with the low temperature melting fibers. In another alternate embodiment, the high strength fibers are coated with the low temperature melting polymer. The composite mesh is covered on at least one side by a laminating film, and is then cut into the shape of the stent.

    摘要翻译： 用于血管的可生物降解的网膜和薄膜支架由一片由可生物降解的高强度聚合物纤维形成的复合网格材料形成，该聚合物纤维与第二可生物降解的粘合剂聚合物结合在一起，并且在至少一侧上用薄膜 第三种可生物降解的聚合物。 可生物降解的网状物和薄膜材料形成为片材，并且被切割成能够用作支架的形状，例如“带扣”形状，其端部可以以可收缩的可扩张环接合。 在制造可生物降解复合网和膜支架的方法中，复合网优选由由高强度可生物降解的聚合物纤维形成的织物和多个低温熔融的可生物降解的聚合物纤维形成。 在替代实施例中，高强度纤维与低温熔融纤维混合。 在另一个替代实施例中，高强度纤维被低温熔融聚合物涂覆。 复合网在至少一侧用层压膜覆盖，然后切割成支架的形状。

    Stent crimper apparatus with radiation shied
    25.
    发明授权
    Stent crimper apparatus with radiation shied 失效
    带放射线的支架卷边装置

    公开(公告)号：US06309383B1

    公开(公告)日：2001-10-30

    申请号：US09488187

    申请日：2000-01-20

    申请人： Thomas H. Campbell ,  Todd H. Turnlund ,  Robert T. Chang

    发明人： Thomas H. Campbell ,  Todd H. Turnlund ,  Robert T. Chang

    IPC分类号： A61B1700

    CPC分类号： B25B7/00 ,  A61F2/958 ,  A61F2002/9522 ,  A61F2210/0095 ,  B25B27/146

    摘要： A stent crimping apparatus for crimping a deformable radioactive stent onto a deployment device which includes a first jaw member defining a shielded first compression surface, and an opposed, second jaw member defining a shielded second compression surface oriented opposite the first compression surface. The first and second compression surfaces are adapted to collectively form an elongated guide bore formed for axial receipt of the deformable stent and the deployment device therein. To protect against exposure to the radioactive stent, a shield assembly is provided defining an opening into a bore therein which is formed and dimensioned for longitudinal receipt of the deformable stent in an uncrimped condition. A shield assembly defines an opening into the bore, and cooperates with the first and second jaw members to substantially prevent radioactive particles emitted by the radioactive stent from passing out of the crimping apparatus. An operating mechanism is operatively coupled to the first and second jaw members for selective movement between a loading condition and a crimping condition. In the loading condition, the uncrimped stent and the deployment device may be inserted through the opening and into the bore. In the crimping condition, the deformable stent is radially compressed onto the deployment device between the first and second compression surfaces.

    摘要翻译： 一种用于将可变形放射性支架卷曲到展开装置上的支架压接装置，所述展开装置包括限定屏蔽的第一压缩表面的第一钳口构件和限定与第一压缩表面相对定向的屏蔽的第二压缩表面的相对的第二钳口构件。 第一和第二压缩表面适于共同地形成用于轴向容纳可变形支架和其中的展开装置的细长导向孔。 为了防止暴露于放射性支架，设置屏蔽组件，其限定到其中的孔中的开口，其中形成并确定尺寸以使未变形状态的可变形支架的纵向接收。 屏蔽组件限定了孔内的开口，并且与第一和第二钳口构件配合，以基本上防止由放射性支架发射的放射性颗粒从压接装置传出。 操作机构可操作地联接到第一和第二钳口构件，用于在负载状态和压接状态之间的选择性运动。 在装载状态下，未卷曲的支架和展开装置可以通过开口插入孔中。 在卷曲状态下，可变形支架在第一和第二压缩表面之间径向压缩到展开装置上。