公开(公告)号：US20220082566A1

公开(公告)日：2022-03-17

申请号：US17538447

申请日：2021-11-30

Applicant: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION

Inventor： Daniel T. Chiu ,  Changfeng Wu ,  Jiangbo Yu

IPC: G01N33/58 ,  C09K11/06 ,  G01N21/64 ,  C09K11/02

Abstract: The present disclosure provides encoded chromophoric polymer particles that are capable of, for example, optical and/or biomolecular encoding of analytes. The present disclosure also provides suspensions comprising a plurality of encoded chromophoric polymer particles. The present disclosure also provides methods of using the encoded chromophoric polymer particles and systems for performing multiplex analysis with encoded chromophoric polymer particles.

公开(公告)号：US11221336B2

公开(公告)日：2022-01-11

申请号：US16556006

申请日：2019-08-29

Applicant: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION

Inventor： Daniel T. Chiu ,  Changfeng Wu ,  Jiangbo Yu

IPC: G01N33/58 ,  C09K11/06 ,  G01N21/64 ,  C09K11/02

Abstract: The present disclosure provides encoded chromophoric polymer particles that are capable of, for example, optical and/or biomolecular encoding of analytes. The present disclosure also provides suspensions comprising a plurality of encoded chromophoric polymer particles. The present disclosure also provides methods of using the encoded chromophoric polymer particles and systems for performing multiplex analysis with encoded chromophoric polymer particles.

公开(公告)号：US20200371109A1

公开(公告)日：2020-11-26

申请号：US16989491

申请日：2020-08-10

Applicant: University of Washington through its Center for Commercialization

Inventor： Daniel T. Chiu ,  Changfeng Wu ,  Xuanjun Zhang ,  Jiangbo Yu ,  Fangmao Ye

IPC: G01N33/58 ,  B82Y30/00 ,  B82Y40/00 ,  C08G61/12 ,  C08J3/11 ,  C09K11/02 ,  C09K11/06 ,  H01L51/00 ,  B82Y15/00

Abstract: The present invention provides, among other aspects, stabilized chromophoric nanoparticles. In certain embodiments, the chromophoric nanoparticles provided herein are rationally functionalized with a pre-determined number of functional groups. In certain embodiments, the stable chromophoric nanoparticles provided herein are modified with a low density of functional groups. In yet other embodiments, the chromophoric nanoparticles provided herein are conjugated to one or more molecules. Also provided herein are methods for making rationally functionalized chromophoric nanoparticles.

公开(公告)号：US10739349B2

公开(公告)日：2020-08-11

申请号：US15167513

申请日：2016-05-27

Applicant: University of Washington through its Center for Commercialization

Inventor： Daniel T. Chiu ,  Changfeng Wu ,  Xuanjun Zhang ,  Jiangbo Yu ,  Fangmao Ye

IPC: C09K11/06 ,  G01N33/58 ,  B82Y30/00 ,  B82Y40/00 ,  B82Y15/00 ,  H01L51/00 ,  C08G61/12 ,  C08J3/11 ,  C09K11/02

Abstract: The present invention provides, among other aspects, stabilized chromophoric nanoparticles. In certain embodiments, the chromophoric nanoparticles provided herein are rationally functionalized with a pre-determined number of functional groups. In certain embodiments, the stable chromophoric nanoparticles provided herein are modified with a low density of functional groups. In yet other embodiments, the chromophoric nanoparticles provided herein are conjugated to one or more molecules. Also provided herein are methods for making rationally functionalized chromophoric nanoparticles.