TANDEM MASS SPECTROMETRY USING COMPOSITE WAVEFORMS
    21.
    发明申请
    TANDEM MASS SPECTROMETRY USING COMPOSITE WAVEFORMS 审中-公开
    使用复合波形的TANDEM MASS SPECTROMETRY

    公开(公告)号:US20130299693A1

    公开(公告)日:2013-11-14

    申请号:US13877580

    申请日:2011-10-13

    IPC分类号: H01J49/00

    摘要: A tandem mass spectrometer system and method are described, where a composite voltage waveform is applied to so as to trap ion having selected m/z. The trapped ions may be subject to collision induced ionization dissociation (CID) by a selectable discrete frequency voltage waveform positioned so as to be in a notch in a broadband waveform. The resultant ion products may be trapped using a second notch having a center frequency corresponding to the ion product to be trapped. The process may be repeated so as to increase the amount of ions produced, or the process a first resultant ion product to yield a second resultant in product, which may be trapped.

    摘要翻译: 描述了串联质谱仪系统和方法,其中施加复合电压波形以捕获具有选定m / z的离子。 被捕获的离子可能通过可选的离散频率电压波形进行碰撞感应电离解离(CID),该波形定位成宽带波形中的陷波。 可以使用具有对应于待捕获的离子产物的中心频率的第二缺口来捕获所得的离子产物。 可以重复该过程,以便增加产生的离子的量,或者加工第一合成的离子产物以产生可能被捕获的第二产物。

    METHOD AND APPARATUS FOR TRANSMISSION MODE ION/ION DISSOCIATION
    24.
    发明申请
    METHOD AND APPARATUS FOR TRANSMISSION MODE ION/ION DISSOCIATION 有权
    用于传输模式离子/离子解离的方法和装置

    公开(公告)号:US20080128611A1

    公开(公告)日:2008-06-05

    申请号:US11998306

    申请日:2007-11-29

    IPC分类号: H01J49/28

    CPC分类号: H01J49/0072 H01J49/4295

    摘要: A method an apparatus for analyzing biomolecules is described. The method includes injecting and storing one species of ionized molecule in a linear ion trap and injecting second species of oppositely polarity ionized molecule such that the second species is transmitted through the stored first species. The resultant reaction products may be analyzed by a mass analyzed taking account of the remaining charge values. In an aspect, a linear ion trap may be used as the reaction volume, and the ionized species injected along the axis of the trap in a substantially collinear manner. The mass analysis may be performed by mass selective axial ejection or by a mass spectrometer.

    摘要翻译: 描述了用于分析生物分子的装置的方法。 该方法包括将一种离子化分子注入并存储在线性离子阱中并注入第二种相反极性的电离分子,使得第二种通过存储的第一种传播。 可以通过考虑剩余电荷值的质量分析所得到的反应产物。 一方面,可以使用线性离子阱作为反应体积,并且离子化物质以基本上共线的方式沿着阱的轴线注入。 质量分析可以通过质量选择性轴向喷射或通过质谱仪来进行。