公开(公告)号：US20100075701A1

公开(公告)日：2010-03-25

申请号：US12560793

申请日：2009-09-16

申请人： Mingsheng Shang ,  Yan Fu ,  Gang Shao

发明人： Mingsheng Shang ,  Yan Fu ,  Gang Shao

IPC分类号： H04W4/14

CPC分类号： G06Q30/02 ,  H04L12/1859 ,  H04L51/38 ,  H04L67/26 ,  H04W4/14

摘要： A method for pushing messages includes: categorizing a first information according to a first category set, creating a first mapping relation between the first information and a category in the first category set; categorizing a second information sent by a message source according to a second category set, and creating a second mapping relation between the message source that sends the second information and a category in the second category set; sorting out each category in the second category set that matches the corresponding category in the first category set which is in the first mapping relation with the first information according to the relation between the first category in the first category set and the second category in the second category set, and determining the corresponding message source according to the second mapping relation; and pushing the first information to the determined corresponding message source.

摘要翻译： 推送消息的方法包括：根据第一类别集分类第一信息，创建第一信息与第一类别集合中的类别之间的第一映射关系; 对根据第二类别集合的消息源发送的第二信息进行分类，并且在发送第二信息的消息源和第二类别集合中的类别之间创建第二映射关系; 根据第一类别集合中的第一类别和第二类别中的第二类别之间的关系，将与第一类别集合的第一类别集合中的与第一信息相匹配的每个类别与第一信息进行排序 类别集，并根据第二映射关系确定相应的消息源; 并将第一信息推送到确定的相应消息源。

公开(公告)号：US20080172157A1

公开(公告)日：2008-07-17

申请号：US11654259

申请日：2007-01-16

申请人： Ian Brewster Hall ,  Paul Simmons ,  Yan Fu

发明人： Ian Brewster Hall ,  Paul Simmons ,  Yan Fu

IPC分类号： B60R21/013

CPC分类号： B60R21/01 ,  B60R21/013 ,  B60R21/015 ,  B60R21/26 ,  B60R21/268 ,  B60R2021/01027 ,  B60R2021/01218 ,  B60R2021/2636

摘要： A method of inflating an airbag with a fluid includes sending a signal to open a first valve and opening the first valve. The method also includes directing a control pressure through the first valve and toward a second valve. The method further includes throttling the second valve in response to the control pressure. The throttling of the second valve produces a variable inflation mass flow rate of the fluid at a second valve outlet. Opening the first valve and closing the first valve are performed as a step function to achieve a desired predetermined variable inflation mass flow rate of the airbag.

摘要翻译： 使用流体对气囊进行充气的方法包括发送信号以打开第一阀并打开第一阀。 该方法还包括将控制压力引导通过第一阀并朝向第二阀。 该方法还包括响应于控制压力来调节第二阀。 第二阀的节流在第二阀出口处产生可变的膨胀质量流量。 执行打开第一阀并关闭第一阀作为阶梯功能，以实现气囊的期望的预定可变膨胀质量流量。

公开(公告)号：US09667423B2

公开(公告)日：2017-05-30

申请号：US12891476

申请日：2010-09-27

申请人： Yan Fu ,  Nadarajah Asokan ,  Ville Aarni

发明人： Yan Fu ,  Nadarajah Asokan ,  Ville Aarni

IPC分类号： H04L29/06 ,  H04L9/32

CPC分类号： H04L9/3213 ,  H04L9/3234 ,  H04L63/0428 ,  H04L63/083 ,  H04L63/102

摘要： Techniques for accelerated authentication include receiving first data that indicates a first portion of user credentials for a first user but not a second portion. It is verified whether the first portion of user credentials is valid. If the first portion of user credentials is valid, then second data that indicates a valid value for the second portion of user credentials for the first user is sent. Other techniques include receiving first data that indicates a first portion of user credentials for a first user but not a second portion of user credentials for the first user. A first message that indicates the first portion of user credentials is sent to a remote process that initiates authentication of the first user based on the first portion of user credentials before receiving second data that indicates the second portion of user credentials for the first user.

公开(公告)号：US20140308263A1

公开(公告)日：2014-10-16

申请号：US14343694

申请日：2012-09-10

申请人： Yongzhang Luo ,  Peng Liu ,  Xinan Lu ,  Yang Chen ,  Yan Fu ,  Guodong Chang ,  Daifu Zhou

发明人： Yongzhang Luo ,  Peng Liu ,  Xinan Lu ,  Yang Chen ,  Yan Fu ,  Guodong Chang ,  Daifu Zhou

IPC分类号： C12N9/14 ,  C12Q1/34

CPC分类号： C12N9/14 ,  A61K38/18 ,  A61K47/60 ,  C07K14/475 ,  C12Q1/00

摘要： The present invention discloses a new anti-tumor medicament comprising a mutant of endostatin. The mutant comprises a mutation in the ATP-binding site of endostatin and has a decreased ATPase activity and an increased anti-angiogenesis activity.

摘要翻译： 本发明公开了一种新的抗肿瘤药物，其包含内皮抑素的突变体。 突变体包含内皮抑素的ATP结合位点中的突变，并且具有降低的ATP酶活性和增加的抗血管生成活性。

公开(公告)号：US20120128624A1

公开(公告)日：2012-05-24

申请号：US13327621

申请日：2011-12-15

申请人： Zailin Yu ,  Yan Fu

发明人： Zailin Yu ,  Yan Fu

IPC分类号： A61K38/38 ,  C12N15/62 ,  C12N15/63 ,  C12N1/19 ,  C12N15/85 ,  C12N15/81 ,  C12N5/10 ,  C12N1/21 ,  C07K19/00 ,  C12N15/82

CPC分类号： A61K38/38 ,  A61K47/643 ,  A61K47/646 ,  C07H21/04 ,  C07K14/47 ,  C07K14/475 ,  C07K14/505 ,  C07K14/52 ,  C07K14/54 ,  C07K14/5403 ,  C07K14/5431 ,  C07K14/765 ,  C07K14/79 ,  C07K2319/00 ,  Y02A50/463 ,  A61K2300/00

摘要： Compositions, kits and methods are provided for promoting general health or for prevention or treatment of diseases by using novel recombinant fusion proteins of human serum albumin (HSA) and bioactive molecules. The bioactive molecules may be a protein or peptide having a biological function in vitro or in vivo, and preferably, having a therapeutic activity when administered to a human. By fusing the bioactive molecule to HSA, stability of the bioactive molecule in vivo can be improved and the therapeutic index increased due to reduced toxicity and longer-lasting therapeutic effects in vivo. In addition, manufacturing processes are provided for efficient, cost-effective production of these recombinant proteins in yeast.

摘要翻译： 提供了通过使用人血清白蛋白（HSA）和生物活性分子的新型重组融合蛋白来促进一般健康或预防或治疗疾病的组合物，试剂盒和方法。 生物活性分子可以是在体外或体内具有生物学功能的蛋白质或肽，并且优选地，当施用于人时具有治疗活性。 通过将生物活性分子融合到HSA中，可以改善体内生物活性分子的稳定性，并且由于体内毒性降低和持久的治疗效果，治疗指数增加。 此外，提供制造方法用于在酵母中有效，成本有效地生产这些重组蛋白。

公开(公告)号：US20120079570A1

公开(公告)日：2012-03-29

申请号：US12891476

申请日：2010-09-27

申请人： Yan Fu ,  Nadarajah Asokan ,  Ville Aarni

发明人： Yan Fu ,  Nadarajah Asokan ,  Ville Aarni

IPC分类号： H04L9/32

CPC分类号： H04L9/3213 ,  H04L9/3234 ,  H04L63/0428 ,  H04L63/083 ,  H04L63/102

摘要： Techniques for accelerated authentication include receiving first data that indicates a first portion of user credentials for a first user but not a second portion. It is verified whether the first portion of user credentials is valid. If the first portion of user credentials is valid, then second data that indicates a valid value for the second portion of user credentials for the first user is sent. Other techniques include receiving first data that indicates a first portion of user credentials for a first user but not a second portion of user credentials for the first user. A first message that indicates the first portion of user credentials is sent to a remote process that initiates authentication of the first user based on the first portion of user credentials before receiving second data that indicates the second portion of user credentials for the first user.

摘要翻译： 用于加速认证的技术包括接收指示第一用户的用户凭证的第一部分而不是第二部分的第一数据。 验证用户凭据的第一部分是否有效。 如果用户凭证的第一部分有效，则发送指示用于第一用户的第二部分用户凭证的有效值的第二数据。 其他技术包括接收指示第一用户的用户凭证的第一部分的第一数据，而不是第一用户的用户凭证的第二部分。 指示用户凭证的第一部分的第一消息被发送到远程进程，该远程进程在接收指示第一用户的用户凭证的第二部分的第二数据之前，基于用户凭证的第一部分来发起对第一用户的认证。

公开(公告)号：US08084021B2

公开(公告)日：2011-12-27

申请号：US12203116

申请日：2008-09-02

申请人： Zailin Yu ,  Yan Fu

发明人： Zailin Yu ,  Yan Fu

IPC分类号： C07K14/52 ,  A61K38/20

CPC分类号： A61K38/38 ,  A61K47/643 ,  A61K47/646 ,  C07H21/04 ,  C07K14/47 ,  C07K14/475 ,  C07K14/505 ,  C07K14/52 ,  C07K14/54 ,  C07K14/5403 ,  C07K14/5431 ,  C07K14/765 ,  C07K14/79 ,  C07K2319/00 ,  Y02A50/463 ,  A61K2300/00

摘要： Compositions, kits and methods are provided for promoting general health or for prevention or treatment of diseases by using novel recombinant fusion proteins of human serum albumin (HSA) and bioactive molecules. The bioactive molecules may be a protein or peptide having a biological function in vitro or in vivo, and preferably, having a therapeutic activity when administered to a human. By fusing the bioactive molecule to HSA, stability of the bioactive molecule in vivo can be improved and the therapeutic index increased due to reduced toxicity and longer-lasting therapeutic effects in vivo. In addition, manufacturing processes are provided for efficient, cost-effective production of these recombinant proteins in yeast.

摘要翻译： 提供了通过使用人血清白蛋白（HSA）和生物活性分子的新型重组融合蛋白来促进一般健康或预防或治疗疾病的组合物，试剂盒和方法。 生物活性分子可以是在体外或体内具有生物学功能的蛋白质或肽，并且优选地，当施用于人时具有治疗活性。 通过将生物活性分子融合到HSA中，可以改善体内生物活性分子的稳定性，并且由于体内毒性降低和持久的治疗效果，治疗指数增加。 此外，提供制造方法用于在酵母中有效，成本有效地生产这些重组蛋白。

公开(公告)号：US20070253409A1

公开(公告)日：2007-11-01

申请号：US10590375

申请日：2005-03-24

申请人： Yan Fu ,  Haitao Hu

发明人： Yan Fu ,  Haitao Hu

IPC分类号： H04L12/28

CPC分类号： H04L12/185 ,  H04L29/12009 ,  H04L29/12783 ,  H04L61/35 ,  H04L63/101 ,  H04L63/104

摘要： The present invention discloses a method for implementing multicast services, which includes: preset a mapping relation between a multicast user address and a multicast group address; acquire a request packet sent by the multicast user who requests to join in the multicast group; determine whether the multicast group address in request packet is the same as that corresponding to the multicast user in the established mapping relation according to the multicast user address and multicast group address carried in the request packet. If yes, allow the multicast user to join in the multicast group. Otherwise, reject the multicast user from joining in the multicast group. The present invention can open the preset multicast resources to the preset multicast user with speed and pertinence. At the same time, it limits the maximum number of multicast groups that each multicast user is allowed to join in, which can effectively control multicast service bandwidth and further protect the network equipment.

摘要翻译： 本发明公开了一种实现组播业务的方法，包括：预先配置组播用户地址与组播组地址之间的映射关系; 获取请求加入组播组的组播用户发送的请求报文; 根据组播用户地址和请求包中携带的组播组地址，确定请求报文中的组播组地址是否与建立的映射关系中的组播用户对应的组播组地址相同。 如果是，允许组播用户加入组播组。 否则，拒绝组播用户加入组播组。 本发明可以以预定的组播用户的速度和针对性开放预设的组播资源。 同时限制了每个组播用户可以加入的组播组的最大数量，从而有效地控制组播业务带宽，进一步保护网络设备。

公开(公告)号：US07244833B2

公开(公告)日：2007-07-17

申请号：US10609346

申请日：2003-06-26

申请人： Zailin Yu ,  Yan Fu

发明人： Zailin Yu ,  Yan Fu

IPC分类号： C12N5/10 ,  C12N15/19 ,  C12N15/62 ,  C12N15/63 ,  C12N15/64

CPC分类号： A61K38/38 ,  A61K47/643 ,  A61K47/646 ,  C07H21/04 ,  C07K14/47 ,  C07K14/475 ,  C07K14/505 ,  C07K14/52 ,  C07K14/54 ,  C07K14/5403 ,  C07K14/5431 ,  C07K14/765 ,  C07K14/79 ,  C07K2319/00 ,  Y02A50/463 ,  A61K2300/00

摘要： Compositions, kits and methods are provided for promoting general health or for prevention or treatment of diseases by using novel recombinant fusion proteins of human serum albumin (HSA) and bioactive molecules. The bioactive molecules may be a protein or peptide having a biological function in vitro or in vivo, and preferably, having a therapeutic activity when administered to a human. By fusing the bioactive molecule to HSA, stability of the bioactive molecule in vivo can be improved and the therapeutic index increased due to reduced toxicity and longer-lasting therapeutic effects in vivo. In addition, manufacturing processes are provided for efficient, cost-effective production of these recombinant proteins in yeast.

摘要翻译： 提供了通过使用人血清白蛋白（HSA）和生物活性分子的新型重组融合蛋白来促进一般健康或预防或治疗疾病的组合物，试剂盒和方法。 生物活性分子可以是在体外或体内具有生物学功能的蛋白质或肽，并且优选地，当施用于人时具有治疗活性。 通过将生物活性分子融合到HSA中，可以改善体内生物活性分子的稳定性，并且由于体内毒性降低和持久的治疗效果，治疗指数增加。 此外，提供制造方法用于在酵母中有效，成本有效地生产这些重组蛋白。

公开(公告)号：US20050048523A1

公开(公告)日：2005-03-03

申请号：US10766102

申请日：2004-01-27

申请人： Patrick Schnable ,  Feng Liu ,  Yan Fu

发明人： Patrick Schnable ,  Feng Liu ,  Yan Fu

IPC分类号： C12N1/15 ,  C12N1/21 ,  C12N15/10 ,  C12N15/62 ,  C12Q1/68 ,  C07H21/04

CPC分类号： C12N15/1086 ,  C07K2319/21 ,  C12N15/1065 ,  C12N15/62

摘要： Compositions and methods for identifying nucleotide fragments that contain an open reading frame are provided. Compositions comprise a nucleotide sequence that encodes, in each of the three possible reading frames, an ATG start codon and a histidine tag, and vectors comprising such a nucleotide sequence. The vectors may be provided with cloning sites for insertion of nucleotide sequences of interest 5′ or 3′ to the 3-frame His-tag DNA sequence. Vectors also are provided with cloning sites for inserting nucleotide sequences of interest 3′ of the ATG start codon and 5′ of the 3-frame His-tag DNA sequence.

摘要翻译： 提供了用于鉴定包含开放阅读框架的核苷酸片段的组合物和方法。 组合物包含在三个可能的阅读框中的每一个中编码ATG起始密码子和组氨酸标签的核苷酸序列，以及包含这种核苷酸序列的载体。 可以向载体提供用于将感兴趣的5'或3'的核苷酸序列插入3框架His标签DNA序列的克隆位点。 载体还提供有用于插入ATG起始密码子的3'和3框His标签DNA序列的5'的感兴趣的核苷酸序列的克隆位点。