公开(公告)号：US09630012B2

公开(公告)日：2017-04-25

申请号：US14820192

申请日：2015-08-06

申请人： Meagan Medical, Inc.

发明人： William J. Carroll

IPC分类号： A61N1/18 ,  A61N1/36 ,  A61N1/05 ,  A61N1/06

CPC分类号： A61N1/36157 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/06 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36171 ,  A61N1/36182

摘要： A stimulator and a method for the treatment of intractable pain syndromes by electrical stimulation of the spinal cord is disclosed. An example method includes positioning a first pair of implantable electrodes to a dura matter in an epidural space proximate to a subject's spinal cord at predetermined locations, positioning a second pair of implantable electrodes to the dura matter in the epidural space proximate to the subject's spinal cord at predetermined locations, and transmitting signals of first and second frequencies through the first and second pairs of implantable electrodes respectively, so that the signals of the first and second frequencies interfere with each other to produce at least one beat signal proximate to the subject's spinal cord. The at least one beat signal has a frequency within a range of more than 250 Hz to about 15,000 Hz.

公开(公告)号：US08977363B2

公开(公告)日：2015-03-10

申请号：US10761424

申请日：2004-01-22

申请人： William J. Carroll ,  Richard M. Terrell

发明人： William J. Carroll ,  Richard M. Terrell

IPC分类号： A61N1/34 ,  A61N1/40 ,  A61N1/05 ,  A61N1/36

CPC分类号： A61N1/36071 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/36153 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36185 ,  A61N1/36192 ,  A61N1/40

摘要： A stimulator and a method for the treatment of intractable pain syndromes by electrical stimulation of the spinal cord is disclosed in which implantable electrodes positioned around a targeted area of the spinal cord transmit an interferential current that has a base medium frequency alternating current between 500 Hz-20 KHz. A digital signal processor generates a sine-wave-like waveform from a pulse generator which after further processing is used to generate at least two circuits for use in producing the interferential current. An effective area of stimulation is controlled by the quantity of electrodes, positioning of the electrodes and electrode cross pattern orientation. Amplitude modulation of electrical circuits created at the electrode placements also augments the effective area of stimulation. The stimulator and method reduce accommodation of the body to the electrical stimulation and provide deeper penetration of the resultant signal.

摘要翻译： 公开了一种通过电刺激脊髓治疗难治性疼痛综合征的刺激器和方法，其中位于脊髓的目标区域周围的可植入电极传输干涉电流，所述干扰电流具有500Hz- 20 KHz。 数字信号处理器从脉冲发生器产生正弦波状波形，该脉冲发生器在进一步处理之后产生用于产生干扰电流的至少两个电路。 刺激的有效区域由电极的数量，电极的定位和电极交叉图案取向来控制。 在电极放置处产生的电路的幅度调制也增加了刺激的有效面积。 刺激器和方法减少身体对电刺激的适应并且提供所得到的信号的更深的穿透。

公开(公告)号：US08805521B2

公开(公告)日：2014-08-12

申请号：US13709788

申请日：2012-12-10

申请人： Meagan Medical, Inc.

发明人： William J. Carroll

IPC分类号： A61N1/00

CPC分类号： A61N1/36003 ,  A61N1/0452 ,  A61N1/0456 ,  A61N1/0472 ,  A61N1/0476 ,  A61N1/326 ,  A61N1/36014

摘要： An apparatus and method for improving mobility and/or the quality of synovial fluid of an affected articular joint are disclosed, wherein the joint is associated with at least a first muscle group and at least a second muscle group each having an antagonistic relationship for effecting mobility of the joint through a range of motion when recruited by natural neural impulses. An electro-medical device is configured to apply motor-level electrical stimulation in a multiphasic pattern via at least a first channel and at least a second channel. An applicator is worn on the articular segment such that the at least two first electrodes and the at least two second electrodes are disposed between the applicator and the articular segment and reduces compressive forces on at least one compartment of the affected joint.

摘要翻译： 公开了一种用于改善受影响的关节关节的滑液的移动性和/或质量的装置和方法，其中所述关节与至少第一肌肉组和至少第二肌肉组相关联，每个具有拮抗关系以影响移动性 的关节通过自然神经冲动招募的一系列运动。 电医疗装置被配置为经由至少第一通道和至少第二通道以多相模式施加电动机电刺激。 施用器佩戴在关节段上，使得至少两个第一电极和至少两个第二电极设置在施用器和关节部分之间，并且减小受影响关节的至少一个隔室上的压缩力。

公开(公告)号：US06904324B2

公开(公告)日：2005-06-07

申请号：US09928044

申请日：2001-08-11

申请人： Jon M. Bishay

发明人： Jon M. Bishay

IPC分类号： A61H39/00 ,  A61H39/08 ,  A61N1/05 ,  A61N1/34 ,  A61N1/36

CPC分类号： A61N1/0502 ,  A61N1/0551 ,  A61N1/36017 ,  A61N1/36021

摘要： An apparatus for piercing a skin surface, and methods for operating and manufacturing such an apparatus. In one embodiment, the apparatus can include a support housing having an engaging surface to engage the skin surface. A releasable attachment member can releasably secure the housing to the skin surface, for example, with an adhesive bond. A stop member can operatively engage a percutaneous probe of the apparatus to at least restrict the ability of the probe to be re-used.

摘要翻译： 用于刺穿皮肤表面的装置，以及用于操作和制造这种装置的方法。 在一个实施例中，该装置可以包括具有接合表面以与皮肤表面接合的支撑壳体。 可释放的附接构件可以例如利用粘合剂粘合将壳体可释放地固定到皮肤表面。 停止构件可操作地接合装置的经皮探针以至少限制探针重新使用的能力。

公开(公告)号：US20220355110A1

公开(公告)日：2022-11-10

申请号：US17865199

申请日：2022-07-14

申请人： Meagan Medical, Inc.

发明人： William J. Carroll

IPC分类号： A61N1/36 ,  A61N1/05

摘要： An example method for spinal cord stimulation treatment includes positioning eight implantable electrodes to a dura matter in an epidural space proximate to a subject's spinal cord so that (i) a first circuit is created between a first and second electrode on a first channel, (ii) a second circuit is created between a third and fourth electrode on a second channel, (iii) a third circuit is created between a fifth and sixth electrode on a third channel, and (iv) a fourth circuit is created between a seventh and eighth electrode on a fourth channel, transmitting signals through the first and second circuits that interfere to produce a first beat signal, transmitting signals through the third and fourth circuits that interfere to produce a second beat signal, and interaction of the first and second beat signals results in a combined beat signal proximate to the subject's spinal cord.

公开(公告)号：US20210138245A1

公开(公告)日：2021-05-13

申请号：US17081129

申请日：2020-10-27

申请人： Meagan Medical, Inc.

发明人： William J. Carroll

IPC分类号： A61N1/36 ,  A61N1/05

摘要： An example method for spinal cord stimulation treatment includes positioning eight implantable electrodes to a dura matter in an epidural space proximate to a subject's spinal cord so that (i) a first circuit is created between a first and second electrode on a first channel, (ii) a second circuit is created between a third and fourth electrode on a second channel, (iii) a third circuit is created between a fifth and sixth electrode on a third channel, and (iv) a fourth circuit is created between a seventh and eighth electrode on a fourth channel, transmitting signals through the first and second circuits that interfere to produce a first beat signal, transmitting signals through the third and fourth circuits that interfere to produce a second beat signal, and interaction of the first and second beat signals results in a combined beat signal proximate to and/or within the subject's spinal cord.

公开(公告)号：US10661083B2

公开(公告)日：2020-05-26

申请号：US15940138

申请日：2018-03-29

申请人： Meagan Medical, Inc.

发明人： William J. Carroll ,  Mark E. Schoening ,  Patrick A. Scranton ,  William R. Huseby

IPC分类号： A61N1/36 ,  A61N1/04

摘要： A CFS system includes self-adhesive, disposable pads. Each pad is combined with a sealed, cleanable battery/controller pod and then placed on the body where needed. The battery/controller pod preferably has wireless capability, such as Bluetooth® capability. The patient can download an application to a smartphone or similar mobile device to control the pods.

公开(公告)号：US09604062B2

公开(公告)日：2017-03-28

申请号：US15076834

申请日：2016-03-22

申请人： Meagan Medical, Inc.

发明人： William J. Carroll

IPC分类号： A61N1/36 ,  A61N1/05 ,  A61N1/40

CPC分类号： A61N1/36071 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/36153 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36185 ,  A61N1/36192 ,  A61N1/40

摘要： A stimulator and a method for the treatment of intractable pain syndromes by electrical stimulation of the spinal cord is disclosed in which implantable electrodes positioned around a targeted area of the spinal cord transmit an interferential current that has a base medium frequency alternating current between 500 Hz-20 KHz. A digital signal processor generates a sine-wave-like waveform from a pulse generator which after further processing is used to generate at least two circuits for use in producing the beat frequency signal. An effective area of stimulation is controlled by the quantity of electrodes, positioning of the electrodes and electrode cross pattern orientation. Amplitude modulation of electrical circuits created at the electrode placements also augments the effective area of stimulation. The stimulator and method reduce accommodation of the body to the electrical stimulation and provide deeper penetration of the resultant signal.

公开(公告)号：US20130165829A1

公开(公告)日：2013-06-27

申请号：US13709788

申请日：2012-12-10

申请人： Meagan Medical, Inc.

发明人： William J. CARROLL

IPC分类号： A61N1/36 ,  A61F5/01

CPC分类号： A61N1/36003 ,  A61N1/0452 ,  A61N1/0456 ,  A61N1/0472 ,  A61N1/0476 ,  A61N1/326 ,  A61N1/36014

摘要： An apparatus and method for improving mobility and/or the quality of synovial fluid of an affected articular joint are disclosed, wherein the joint is associated with at least a first muscle group and at least a second muscle group each having an antagonistic relationship for effecting mobility of the joint through a range of motion when recruited by natural neural impulses. An electro-medical device is configured to apply motor-level electrical stimulation in a multiphasic pattern via at least a first channel and at least a second channel. An applicator is worn on the articular segment such that the at least two first electrodes and the at least two second electrodes are disposed between the applicator and the articular segment and reduces compressive forces on at least one compartment of the affected joint.

摘要翻译： 公开了一种用于改善受影响的关节关节的滑液的移动性和/或质量的装置和方法，其中所述关节与至少第一肌肉组和至少第二肌肉组相关联，每个具有拮抗关系以影响移动性 的关节通过自然神经冲动招募的一系列运动。 电医疗装置被配置为经由至少第一通道和至少第二通道以多相模式施加电动机电刺激。 施用器佩戴在关节段上，使得至少两个第一电极和至少两个第二电极设置在施用器和关节部分之间，并且减小受影响关节的至少一个隔室上的压缩力。

公开(公告)号：US08417352B2

公开(公告)日：2013-04-09

申请号：US12769382

申请日：2010-04-28

申请人： William J. Carroll ,  Erling Jensen Aune, Jr. ,  Timothy J. Johnson ,  Jens Olaf Roe Schouenborg

发明人： William J. Carroll ,  Erling Jensen Aune, Jr. ,  Timothy J. Johnson ,  Jens Olaf Roe Schouenborg

IPC分类号： A61N1/00 ,  A61B5/04

CPC分类号： A61N1/0456 ,  A61N1/0452 ,  A61N1/0476 ,  A61N1/0492 ,  A61N1/0502 ,  A61N1/0551 ,  A61N1/36014 ,  A61N1/36017 ,  A61N1/36021

摘要： An electrotherapy system for stimulating sensory nerves within skin tissue includes a electrode carrier, a pulse generator, an array of skin-penetrating electrodes and surface skin electrodes, a pulse conditioning circuit, and a power source. The system administers biphasic pulsed current at the surface skin electrodes and monophasic pulsed current at each skin-penetrating electrode. The skin-penetrating surfaces and skin contact surfaces of the electrotherapy system may be sterilized or may be replaceable for outpatient reusability.

摘要翻译： 用于刺激皮肤组织内的感觉神经的电疗系统包括电极载体，脉冲发生器，皮肤穿透电极阵列和表面皮肤电极，脉冲调节电路和电源。 该系统在每个皮肤穿透电极处施加表面电极处的双相脉冲电流和单相脉冲电流。 电疗系统的皮肤穿透表面和皮肤接触表面可以被灭菌或可以替换为门诊可重用性。