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公开(公告)号:US10225899B2
公开(公告)日:2019-03-05
申请号:US15565768
申请日:2016-03-17
Applicant: KOWA COMPANY, LTD.
Inventor: Yutaka Mizukusa , Kenichi Inoue , Kazuhiro Kashiwagi , Ayafumi Taniji
Abstract: A lighting system for plant cultivation comprises a light source, a light source driving unit that drives the light source, and a control unit that transmits a pulse signal to the light source driving unit. The control unit comprises a first pulse generating unit that generates a first pulse signal (S1) of a predetermined frequency, a second pulse generating unit that generates a second pulse signal (S2) of a frequency different from the predetermined frequency, and a pulse signal selecting unit that selects any one of the first pulse signal (S1) and the second pulse signal (S2) to transmit the selected one to the light source driving unit. The light source driving unit includes a frequency determining unit that determines whether the frequency of the pulse signal received from the control unit is the frequency of the first pulse signal (S1) or the frequency of the second pulse signal (S2), a first driving unit that, when receiving the first pulse signal (S1) from the control unit, converts the first pulse signal (S1) to a constant current, output to drive the light source, and a second driving unit that, when receiving the second pulse signal (S2) from the control unit, outputs a pulse with an original pulse waveform of the second pulse signal (S2) to drive the light source.
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公开(公告)号:US10195019B2
公开(公告)日:2019-02-05
申请号:US15037469
申请日:2014-11-19
Applicant: KOWA COMPANY, LTD.
Inventor: Takashi Sato
IPC: A61F2/16
Abstract: An intraocular lens insertion apparatus includes an accommodating member integrally or independently formed on an apparatus body which is inserted into an eyeball, allowing arrangement of the intraocular lens in the apparatus body by accommodating the intraocular lens therein, and having a hole through which a needle of a syringe which supplies a lubricant to the intraocular lens passes. Further, the intraocular lens insertion apparatus includes a guide wall member formed on the accommodating member at a position adjacent to the hole, and being configured to guide the needle of the syringe to the hole.
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公开(公告)号:US10164741B2
公开(公告)日:2018-12-25
申请号:US15521930
申请日:2015-10-21
Applicant: KOWA COMPANY, LTD.
Inventor: Tomohisa Azegami , Tatsuya Kimbara , Masatomo Ohmaki
IPC: H04L12/26 , H04L1/08 , H04L1/00 , H04B17/309
Abstract: [Problem]To prevent either of two packet data having the same content from being affected by noise[Solution]A packet data transmission device (not shown) transmits first packet data 1A, . . . and second packet data 1B, . . . having the same content intermittently with an idle time I therebetween. When the length of the first and second packet data 1A, . . . , 1B, . . . is denoted by LP, the length of the idle time I is denoted by LI, the duration of low-frequency noise N is denoted by LN, the time with no low-frequency noise from the occurrence of one low-frequency noise N to the occurrence of the next low-frequency noise N is denoted by LC, the following expressions (1), (2) are satisfied. Consequently, either the first packet data or the second packet data is transmitted to a receiver without being affected by noise. LI>LN (1) 2×LP+LI
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公开(公告)号:US20180325913A1
公开(公告)日:2018-11-15
申请号:US15976135
申请日:2018-05-10
Applicant: JUNTENDO EDUCATIONAL FOUNDATION , KOWA COMPANY, LTD.
Inventor: Takenori INOMATA , Toshinari Funaki
IPC: A61K31/551 , A61K9/00 , A61P27/02
CPC classification number: A61K31/551 , A61K9/0048 , A61K9/08 , A61P27/02
Abstract: To provide a novel method for suppressing rejection after corneal transplantation.The method for suppressing rejection after corneal transplantation includes administering an effective amount of a Rho kinase inhibitor to a patient who needs it.
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公开(公告)号:US20180232886A1
公开(公告)日:2018-08-16
申请号:US15752946
申请日:2016-08-09
Applicant: KOWA COMPANY, LTD. , Casio Computer Co., Ltd.
Inventor: Toshiaki NAKAGAWA , Takao SHINOHARA , Yasushi MAENO , Akira HAMADA
CPC classification number: G06T7/13 , A61B3/10 , A61B3/102 , G06T1/00 , G06T7/0014 , G06T7/143 , G06T2207/10101 , G06T2207/20076 , G06T2207/30041
Abstract: Edges of layers are detected from an input image to create a boundary line candidate image that represents the detected edges. A luminance value of the input image is differentiated to create a luminance value-differentiated image that represents luminance gradient of the layers. An evaluation score image is created which is obtained by weighting calculation at an optimum ratio between a boundary line position probability image and the luminance value-differentiated image. The boundary line position probability image is obtained from the boundary line candidate image and an existence probability image that represents existence of a boundary line to be extracted. A route having the highest total evaluation score is extracted as the boundary line. According to such an image processing apparatus and image processing method, boundary lines of layers can be extracted with a high degree of accuracy from a captured image of a target object composed of a plurality of layers.
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公开(公告)号:US20180028506A1
公开(公告)日:2018-02-01
申请号:US15663787
申请日:2017-07-30
Applicant: Kowa Company, Ltd.
Inventor: Ryu Oshima , Gary Gordon
IPC: A61K31/423 , A61K9/00
CPC classification number: A61K31/423 , A61K9/0053 , A61K31/366 , A61K31/40 , A61K31/41 , A61K31/47 , A61K31/505 , A61K45/06
Abstract: The present invention relates to pharmacological interventions with pemafibrate for cardiovascular diseases and adverse cardiovascular events. In addition, the invention relates to the use of pemafibrate to treat dyslipidemia and type 2 diabetes mellitus and thereby reduce the risk of cardiovascular disease and adverse cardiovascular events.
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297.
公开(公告)号:US09844556B2
公开(公告)日:2017-12-19
申请号:US15079934
申请日:2016-03-24
Applicant: Megumi Honjo , KOWA COMPANY, LTD.
Inventor: Megumi Honjo , Eiji Wato , Masayuki Ohta
IPC: A61K31/551 , A61K9/00 , A61K9/08
CPC classification number: A61K31/551 , A61K9/0048 , A61K9/08
Abstract: The present invention provides a method for the prevention and treatment of complications after cataract surgery such as secondary cataract and anterior capsule contraction that occur after cataract operation.The present invention relates to a preventive/therapeutic method comprising administering to a subject a medicine containing 4-fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline (Ripasudil) or a salt thereof, or a solvate thereof as an active ingredient.
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公开(公告)号:US09826897B2
公开(公告)日:2017-11-28
申请号:US15118651
申请日:2015-02-09
Applicant: KOWA COMPANY, LTD.
Inventor: Satoshi Shimada , Takuya Hara
CPC classification number: A61B3/024 , A61B3/0008 , A61B3/0025 , A61B3/0033 , A61B3/0041 , A61B3/0058 , A61B3/0091 , A61B3/12
Abstract: In a perimetry to be conducted, designating an inspection region through a region designator, stimuli are presented to regions separated in an up/down direction, an oblique direction and a right/left direction from the inspection region (“the spaced region”) in addition to the designated inspection region. At the result, examinees are not able to predict to which of both regions, the inspection region and the spaced region the stimuli are presented, thereby obtaining correct inspection results that do not receive a prediction of the examinees.
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公开(公告)号:US20170304274A1
公开(公告)日:2017-10-26
申请号:US15513609
申请日:2015-09-28
Applicant: KOWA COMPANY, LTD.
Inventor: Yuta Inokuchi , Toshiaki Takizawa
IPC: A61K31/423 , A61K31/455
CPC classification number: A61K31/423 , A61K31/455 , A61K2300/00
Abstract: This invention provides a combination-drug composition and a combination use of pharmaceuticals for preventing and/or treating dyslipidemic conditions such as hyper-LDL cholesterolemia in mammals, including humans. This invention pertains to a drug composition for preventing and or treating dyslipidemia and the like, the drug composition including the following: (R)-2-[3-[[N-(benzoxazol-2-yl)-N-3-(4-methoxyphenoxy)propyl]aminomethyl]phenoxy] butyric acid, a salt thereof, or a solvate of either; and nicotinic acid and nicotinic-acid amide, collectively referred to as niacin, an ester derivative thereof, a salt thereof, or a solvate of any of these.
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公开(公告)号:US20170304199A1
公开(公告)日:2017-10-26
申请号:US15514155
申请日:2015-09-25
Applicant: KOWA COMPANY, LTD.
Inventor: Hiroshi ODA , Yuuki SUZUKI
IPC: A61K9/08 , C08K5/3475 , B65D81/30 , A61K31/551 , C08K3/22 , A61J1/14
CPC classification number: A61K9/08 , A61J1/1468 , A61K31/551 , A61P27/02 , A61P27/06 , B65D81/30 , C08K3/22 , C08K5/3475 , C08K2003/2241
Abstract: A technique is provided for improving the stability of a halogenated isoquinoline derivative with respect to light in an aqueous composition. A pharmaceutical preparation obtained by storing an aqueous composition comprising a compound represented by Formula (1): wherein X represents a halogen atom,or a salt thereof, or a solvate of the compound or the salt thereof, in a package that blocks a ray with a wavelength of 300 to 335 nm.
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