公开(公告)号：US07637400B2

公开(公告)日：2009-12-29

申请号：US11301659

申请日：2005-12-12

Applicant: Daniel Py ,  Julian V. Chan

Inventor： Daniel Py ,  Julian V. Chan

IPC: B65D5/72

CPC classification number: B65D35/46 ,  B65D47/205 ,  B65D47/2056 ,  B65D47/2081

Abstract: A container and valve assembly for storing and dispensing substances including edible substances. The container is a tubular body that defines a storage chamber for storing the substance and a head portion for supports the valve assembly. The valve assembly includes a valve body and a valve seat surrounded by a flexible outer cover that includes a valve portion. A seem between the valve portion and valve seat form a one-way release valve wherein a portion of the seam remains closed when the substance is dispensed. To dispense the substance, pressure is applied to the body forcing the substance into the valve assembly, which in turn, controls the flow and release of the substance without exposing the remaining substance to the external atmosphere; thus, the sterility of the storage chamber and remaining substance is maintained, and the shelf life of the substance is increased.

Abstract translation: 用于储存和分配包括可食用物质的物质的容器和阀组件。 容器是限定用于储存物质的储存室的管状体和用于支撑阀组件的头部。 阀组件包括阀体和由包括阀部分的柔性外盖包围的阀座。 在阀部分和阀座之间似乎形成单向释放阀，其中当物质被分配时，接缝的一部分保持关闭。 为了分配物质，将压力施加到身体，迫使物质进入阀组件，这进而控制物质的流动和释放，而不将剩余物质暴露于外部大气; 因此，保持储存室和剩余物质的不育性，并且物质的保存期限增加。

公开(公告)号：US07556066B2

公开(公告)日：2009-07-07

申请号：US11527775

申请日：2006-09-25

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65B1/04

CPC classification number: B65B3/04 ,  A61L2/08 ,  A61L2/087 ,  A61L2/24 ,  A61L2202/14 ,  B65B3/003 ,  B65B7/16 ,  B65B7/161 ,  B65B55/025 ,  B65B55/08 ,  B65B55/16

Abstract: A sterile filling machine and related method are provided for sterile filling a container with a substance. The container includes a heat resealable stopper and a chamber for receiving the substance therein. The sealed, empty containers are subjected to radiation capable of penetrating through the stopper and chamber for sterilizing the container. The previously sterilized containers are then transported through another sterilizing chamber, such as an e-beam chamber, to sterilize the penetrable surface. A needle is moved into engagement with the stopper to pierce the sterilized penetrable surface of the stopper and inject the substance through the needle and into the chamber of the container. Laser energy is then transmitted onto the penetrated surface of the stopper to fuse the stopper material and hermetically re-seal the stopper.

Abstract translation: 提供了一种无菌灌装机及相关方法，用于无菌填充具有物质的容器。 容器包括可热再封塞的塞子和用于在其中容纳物质的腔室。 密封的空容器经受能够穿过塞子和室的辐射，以对容器进行灭菌。 先前灭菌的容器然后通过另一个灭菌室，如电子束室输送，以对可穿透表面进行消毒。 针头与塞子移动接合以刺穿塞子的消毒的可渗透表面，并将物质通过针头注入容器的腔室。 然后将激光能量传递到塞子的穿透表面上，以使塞子材料熔化并密封地重新密封塞子。

公开(公告)号：US20090098250A1

公开(公告)日：2009-04-16

申请号：US12245681

申请日：2008-10-03

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65B55/04 ,  B65B55/08 ,  A23L1/29 ,  A23L1/28 ,  A23L2/02 ,  A23C9/20 ,  A23L2/00 ,  B65D85/72 ,  B65D85/80

CPC classification number: A23L3/04 ,  A23L2/46 ,  A23L3/22 ,  B65B3/04 ,  B65B55/025 ,  B65B55/10 ,  B65B55/12

Abstract: An apparatus and method are provided for formulating and aseptically filling liquid products. A first liquid source includes at least one first liquid component; a second liquid source includes at least one second liquid component; and a container includes a body defining an empty, sterile storage chamber therein that is sealed with respect to ambient atmosphere. The container is introduced into a sterile filling chamber. A first filling member coupled in fluid communication with the first liquid source is placed in fluid communication with the storage chamber of the container located in the sterile filling chamber, and the first liquid component is aseptically introduced through the first filling member and into the storage chamber. A second filling member coupled in fluid communication with the second liquid source is placed in fluid communication with the storage chamber of the container located in the sterile filling chamber, and the second liquid component is aseptically introduced through the second filling member and into the storage chamber and, in turn, the first and second liquid components are combined into a liquid product formulation within the sterile chamber of the container. The first and second filling members are withdrawn from fluid communication with the storage chamber of the container located within the sterile filling chamber, and the filled storage chamber is sealed with respect to ambient atmosphere to hermetically seal the liquid product formulation within the storage chamber of the container.

Abstract translation: 提供了用于配制和无菌灌装液体产品的装置和方法。 第一液体源包括至少一个第一液体组分; 第二液体源包括至少一个第二液体组分; 并且容器包括在其中限定相对于环境大气密封的空的无菌储存室的主体。 将容器引入无菌填充室。 与第一液体源流体连通的第一填充构件被放置成与位于无菌填充室中的容器的储存室流体连通，第一液体组分被无菌地通过第一填充构件引入储存室 。 与第二液体源流体连通的第二填充构件被放置成与位于无菌填充室中的容器的储存室流体连通，并且第二液体组分被无菌地通过第二填充构件引入并进入储存室 而又将第一和第二液体组分组合成容器无菌室内的液体产品制剂。 第一和第二填充构件与位于无菌填充室内的容器的储存室流体连通地取出，并且填充的储存室相对于环境大气密封，以将液体产品配制物气密地密封在储存室内 容器。

公开(公告)号：US07500498B2

公开(公告)日：2009-03-10

申请号：US11933300

申请日：2007-10-31

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65B1/20

CPC classification number: A61J1/2096 ,  A61J1/1406 ,  A61J1/1468 ,  A61J1/18 ,  A61L2/08 ,  B29C65/16 ,  B29C65/1616 ,  B29C65/1619 ,  B29C65/1654 ,  B29C65/1677 ,  B29C65/18 ,  B29C66/001 ,  B29C66/1222 ,  B29C66/1224 ,  B29C66/12461 ,  B29C66/1312 ,  B29C66/342 ,  B29C66/534 ,  B29C66/5344 ,  B29C66/542 ,  B29C66/612 ,  B29C66/71 ,  B29C66/73755 ,  B29C66/7392 ,  B29C66/73921 ,  B29C66/7394 ,  B29C66/8322 ,  B29C67/004 ,  B29L2031/7158 ,  B29L2031/753 ,  B65B3/003 ,  B65B7/161 ,  B65D51/002 ,  B29C65/00 ,  B29K2025/08 ,  B29K2023/00

Abstract: A device and method are provided for needle penetrating and filling a chamber with a predetermined substance, and laser resealing a resulting needle hole in the device. A needle penetrable and laser resealable portion of the device is pierceable with a needle to form a needle aperture therethrough to fill the chamber through the needle, and is laser resealable to hermetically seal the needle aperture by applying laser radiation at a predetermined wavelength and power thereto. The needle penetrable and laser resealable portion defines a predetermined wall thickness in an axial direction thereof, and includes a thermoplastic that substantially prevents the formation of particles released into the chamber from the needle penetrable and laser resealable portion during penetration by and withdrawal of the needle. The thermoplastic includes a predetermined amount of pigment that allows the thermoplastic to substantially absorb laser radiation at the predetermined wavelength, substantially prevent the passage of radiation through the predetermined wall thickness thereof, and hermetically seal a needle aperture formed in the needle penetration region thereof in a predetermined time period.

Abstract translation: 提供了用于针刺穿并用预定物质填充腔室的装置和方法，并且激光将所得到的针孔重新密封在装置中。 装置的针穿透和激光可重新密封部分可用针刺穿以形成穿过其的针孔，以通过针填充腔室，并且可激光重新密封以通过施加预定波长的激光辐射和对其进行动力来气密地密封针孔 。 针穿透和激光可再密封部分在其轴向方向上限定预定的壁厚，并且包括热塑性材料，其基本上防止在针穿透和退出针时从针穿透和激光可再密封部分形成释放到腔室中的颗粒。 热塑性塑料包括预定量的颜料，其允许热塑性塑料基本上吸收预定波长的激光辐射，基本上防止辐射通过其预定壁厚，并将形成在其针穿入区域中的针孔密封在 预定时间段。

公开(公告)号：USD586904S1

公开(公告)日：2009-02-17

申请号：US29297810

申请日：2007-11-19

Applicant: Daniel Py ,  Julian V. Chan

Designer： Daniel Py ,  Julian V. Chan

公开(公告)号：USD573036S1

公开(公告)日：2008-07-15

申请号：US29241389

申请日：2005-10-26

Applicant: Daniel Py ,  Nathaniel Houle ,  Eric E. Hartman ,  Miles J. Flamenbaum

Designer： Daniel Py ,  Nathaniel Houle ,  Eric E. Hartman ,  Miles J. Flamenbaum

公开(公告)号：USD573034S1

公开(公告)日：2008-07-15

申请号：US29297161

申请日：2007-11-05

Applicant: Daniel Py ,  Julian V. Chan ,  Stephanie Ferreira ,  Giovanni Rodriguez ,  Luz Gladys Valencia

Designer： Daniel Py ,  Julian V. Chan ,  Stephanie Ferreira ,  Giovanni Rodriguez ,  Luz Gladys Valencia

公开(公告)号：US20080116226A1

公开(公告)日：2008-05-22

申请号：US11949104

申请日：2007-12-03

Applicant: Daniel Py ,  Brian Tulley ,  Jeff Willey ,  Norbert Assion ,  Nathaniel Houle ,  Julian Chan ,  Bing He

Inventor： Daniel Py ,  Brian Tulley ,  Jeff Willey ,  Norbert Assion ,  Nathaniel Houle ,  Julian Chan ,  Bing He

IPC: B65D37/00

CPC classification number: B67D1/10 ,  B05B11/0054 ,  B05B11/303 ,  B05B11/3032 ,  B65D75/5866 ,  B65D75/5883 ,  B65D77/067 ,  B67D1/0082 ,  B67D1/02 ,  B67D2001/0827

Abstract: An apparatus for storing fluid and dispensing multiple portions of a stored fluid therefrom. The apparatus comprises a container defining a variable-volume storage chamber for receiving therein the fluid and a dispensing valve including a valve inlet coupled in fluid communication with the variable volume storage chamber, and a valve member in fluid communication with the valve inlet and defining a normally-closed valve opening. The valve member is responsive to fluid at the valve inlet exceeding a valve opening pressure to move between (i) a normally closed position, and (ii) an open position permitting fluid flow through the valve opening. The dispensing valve defines a dispensing axis defining a direction substantially along which fluid is dispensed from the valve, and further includes an outlet surface over which dispensed fluid flows oriented at an acute angle relative to the dispensing axis for preventing the collection of residual dispensed fluid thereon.

Abstract translation: 一种用于存储流体并从其分配多个储存的流体的装置。 该装置包括限定用于在其中容纳流体的可变容积存储室的容器和包括与可变容积存储室流体连通的阀入口的分配阀，以及与阀入口流体连通并限定一个 常闭阀门开度。 阀构件对阀入口处的流体响应超过阀开启压力以在（i）常闭位置和（ii）允许流体流过阀开口的打开位置之间移动。 分配阀限定了分配轴线，其限定了基本上从阀门分配流体的方向，并且还包括出口表面，分配的流体相对于分配轴线以锐角定向在该出口表面上，用于防止在其上收集剩余的分配流体 。

公开(公告)号：US20080116225A1

公开(公告)日：2008-05-22

申请号：US11900335

申请日：2007-09-10

Applicant: Daniel Py ,  Brian Tulley ,  Jeff Willey ,  Norbert Assion ,  Nathaniel Houle ,  Julian Chan ,  Bing He

Inventor： Daniel Py ,  Brian Tulley ,  Jeff Willey ,  Norbert Assion ,  Nathaniel Houle ,  Julian Chan ,  Bing He

IPC: B65D37/00

CPC classification number: B67D1/10 ,  B05B11/0054 ,  B05B11/303 ,  B05B11/3032 ,  B65D75/5866 ,  B65D75/5883 ,  B65D77/067 ,  B67D1/0082 ,  B67D1/02 ,  B67D2001/0827

Abstract: An apparatus for storing fluid and dispensing multiple portions of the stored fluid has a container defining a variable-volume storage chamber; a dispensing valve including a valve inlet coupled in fluid communication with the variable-volume storage chamber, and an elastic valve member in fluid communication with the valve inlet and defining a normally-closed valve opening; a manually engageable actuator; and a pump including a compressible member defining a compression chamber coupled in fluid communication with the variable-volume storage chamber. Multiple portions of the stored fluid are hermetically sealed in the variable-volume storage chamber. The actuator is manually engageable and movable between (i) a first position wherein the compression chamber defines a first volume, and (ii) a second position wherein the compression chamber defines a second volume less than the first volume. In the second position the fluid in the compression chamber exceeds a valve opening pressure and, in turn, moves the elastic valve member between (i) a normally closed position hermetically sealing the one-way valve and variable-volume storage chamber with respect to ambient atmosphere, and (ii) an open position permitting fluid flow through the valve opening.

Abstract translation: 用于存储流体和分配存储流体的多个部分的装置具有限定可变容积存储室的容器; 分配阀，包括与可变容积存储室流体连通的阀入口和与阀入口流体连通并限定常闭阀开口的弹性阀构件; 可手动接合的致动器; 以及泵，其包括限定与所述可变容积存储室流体连通地联接的压缩室的可压缩构件。 存储流体的多个部分气密地密封在可变容积的储存室中。 致动器可手动地接合并且可在（i）第一位置和第二位置之间移动，其中压缩室限定第一容积，和（ii）第二位置，其中压缩室限定小于第一容积的第二容积。 在第二位置，压缩室中的流体超过阀打开压力，并且使弹性阀构件在（i）气密地将密闭单向阀和可变体积储存室的常闭位置相对于环境 （ii）允许流体流过阀门开口的打开位置。

公开(公告)号：US20080105712A1

公开(公告)日：2008-05-08

申请号：US11897928

申请日：2007-08-31

Applicant: Daniel Py

Inventor： Daniel Py

IPC: G01F11/06

CPC classification number: G01F11/021 ,  B05B11/3001 ,  B05B11/3015 ,  B05B11/3032 ,  B05B11/3047 ,  B05B11/3074 ,  B65D47/2031 ,  B65D83/00 ,  B65D83/0033 ,  B65D83/0072 ,  G01F11/02

Abstract: A dispenser has a housing, and a variable-volume storage chamber formed within the housing and defining a substantially fluid-tight seal between the chamber and exterior of the housing for storing a substance to be dispensed. A piston is mounted within the housing, and a one-way valve is mounted within the housing and coupled in fluid communication with the variable-volume storage chamber. A compression chamber is coupled in fluid communication between the piston and one-way valve, and at least one of the piston and valve is manually depressible relative to the other between (i) a first position in which the piston is located at least partially outside of the compression chamber for permitting substance to flow from the variable-volume storage chamber into the compression chamber, and (ii) a second position in which the piston is located at least partially within the compression chamber for pressurizing substance within the compression chamber above a valve opening pressuring and, in turn, dispensing substance through the one-way valve and out of the dispenser.

Abstract translation: 分配器具有壳体和形成在壳体内的可变容积的储存室，并且在壳体的室和外部之间限定基本上流体密封的密封，用于存储待分配的物质。 活塞安装在壳体内，并且单向阀安装在壳体内并且与可变容积存储室流体连通地联接。 压缩室在活塞和单向阀之间流体连通地联接，并且活塞和阀门中的至少一个在第一位置之间相对于另一个手动地相对地被压下，其中活塞位于至少部分外部 的压缩室，用于允许物质从可变容积的储存室流入压缩室，以及（ii）第二位置，其中活塞至少部分地位于压缩室内，用于将压缩室内的物质加压在压缩室的上方 阀开启压力，而又通过单向阀将分配物质分配到分配器中。