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    In Vitro Oral Biofilm Models of Interdental Spaces and Uses
    361.
    发明申请
    In Vitro Oral Biofilm Models of Interdental Spaces and Uses 审中-公开

    公开(公告)号：US20170322210A1

    公开(公告)日：2017-11-09

    申请号：US15523792

    申请日：2014-11-11

    Applicant: Colgate-Palmolive Company

    Inventor： Hans Stettler ,  Amy Russo RUSSO

    IPC: G01N33/569 ,  C12M1/12 ,  C12Q1/18

    CPC classification number: G01N33/56955 ,  C12M1/12 ,  C12Q1/18

    Abstract: Disclosed is an in vitro oral biofilm model of interdental spaces including: a support, and a plurality of substratum pairs attached to the support, wherein an oral biofilm is capable of forming on the substratum pairs, wherein the substratum pairs each include a first member and a second member, and wherein the first member and the second member of each substratum pair are arranged to form a space interval between the first member and second member. Methods for assessing the formation of oral biofilms using the in vitro oral biofilm model and methods for testing agents, such as oral compositions, on biofilm reduction using the present model are also provided.

    Toothbrush with Enhanced Cleaning Effects
    369.
    发明申请
    Toothbrush with Enhanced Cleaning Effects 审中-公开

    公开(公告)号：US20170245627A1

    公开(公告)日：2017-08-31

    申请号：US15507329

    申请日：2014-09-03

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： Wen Jin XI ,  Guang Sheng GUO ,  Xiang Ji DING

    IPC: A46B9/04 ,  A61C17/34 ,  A61C17/22 ,  A46B9/02 ,  A46B15/00

    Abstract: A toothbrush (100) having a combination of tapered and non-tapered cleaning elements (50) for enhanced cleaning effects and having a plurality of tapered bristle tufts of differing tuft configurations including, a first tapered bristle tuft (500) having a dome-shaped bristle tip profile (520) toward one end (210) of the head (200), a second tapered bristle tuft (602) having an arcuate-shaped bristle configuration (622) toward an opposite end (222) of the head (200), and a plurality of laterally-extending third tapered bristle tufts (600) arranged in an alternating fashion with non-tapered bristle tufts (630) and disposed between the first and second tapered bristle tufts (500, 602).

    Oral Care System and Method
    370.
    发明申请
    Oral Care System and Method 审中-公开

    公开(公告)号：US20170238689A1

    公开(公告)日：2017-08-24

    申请号：US15503631

    申请日：2014-08-14

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： Robert MOSKOVICH ,  Matthew KOLB

    IPC: A46B11/00 ,  A46B9/04

    CPC classification number: A46B11/0055 ,  A46B9/04 ,  A46B11/0041 ,  A46B2200/1066

    Abstract: An oral care system includes a toothbrush and a dispenser detachably coupled to the toothbrush. The dispenser includes a collapsible bladder containing an oral care material. A compression device assembly includes an actuator operably coupled to a compression device movably mounted inside the dispenser. In one embodiment, the compression device includes a feed slot that engages opposite sides of the collapsible bladder. Actuating the actuator translates the compression device in a first longitudinal direction extruding and dispensing the oral care material from the oral care product dispenser. The actuator may be slideably mounted to the dispenser in one embodiment. A ratcheting mechanism may be provided to provide indexed movement of the compression device, thereby dispensing predetermined doses of the oral care material with each indexed movement.

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