Dispenser and apparatus and method for filling a dispenser
    362.
    发明申请
    Dispenser and apparatus and method for filling a dispenser 有权
    分配器以及用于填充分配器的装置和方法

    公开(公告)号:US20060124197A1

    公开(公告)日:2006-06-15

    申请号:US11349873

    申请日:2006-02-08

    Abstract: A dispenser for holding multiple doses of fluids or other substances, and for dispensing the substances, has a vial, a flexible bladder received within the vial, and a variable volume storage chamber formed between the bladder and vial. A filling valve is coupled in fluid communication with the storage chamber and defines (1) a normally closed, fluid-tight position hermetically sealing the storage chamber from the ambient atmosphere, and (2) an open position allowing the passage of fluid through the valve both to evacuate the storage chamber and to introduce fluid through the valve to fill the storage chamber. A pump is coupled in fluid communication with the storage chamber for pumping fluids out of the storage chamber. A dispensing valve is coupled in fluid communication with the pump and defines (1) a normally closed, fluid-tight position preventing the passage of fluid out of the dispenser, and (2) an open position for dispensing pumped fluid therethrough. The sealed, empty dispenser is sterilized, such as by applying gamma radiation thereto. Then, the sterilized, sealed, empty dispenser is filled with fluid by engaging the filling valve with an evacuating/dispensing member to evacuate the storage chamber, and by introducing fluid from the filling member through the open filling valve and into the storage chamber. The filling member is withdrawn from the valve, and a spring moves the valve to a closed position to hermetically seal the fluid within the dispenser.

    Abstract translation: 用于保持多个剂量的流体或其它物质并用于分配物质的分配器具有小瓶,容纳在小瓶内的柔性囊,以及形成在膀胱和小瓶之间的可变体积存储室。 填充阀与储存室流体连通地联接并且限定(1)将储存室与环境大气密封的常闭密封的流体密封位置,和(2)允许流体通过阀门的打开位置 两者都抽真空储存室并引入流体通过阀门填充储存室。 泵与储存室流体连通地联接,用于将流体泵出储存室。 分配阀与泵流体连通地联接并限定(1)常闭的,流体密封的位置,防止流体从分配器通过,以及(2)用于分配泵送的流体通过的打开位置。 密封的空分配器被灭菌,例如通过对其施加γ射线。 然后,通过使填充阀与排气/分配构件接合以消除储存室,并且通过将来自填充构件的流体通过打开的填充阀引入并进入储存室,灭菌的密封的空分配器充满流体。 填充构件从阀中取出,并且弹簧将阀移动到关闭位置以将分配器内的流体气密地密封。

    Dispenser and apparatus and method for filling a dispenser
    366.
    发明申请
    Dispenser and apparatus and method for filling a dispenser 有权
    分配器以及用于填充分配器的装置和方法

    公开(公告)号:US20050000591A1

    公开(公告)日:2005-01-06

    申请号:US10843902

    申请日:2004-05-12

    Abstract: A dispenser for holding multiple doses of fluids or other substances, and for dispensing the substances, has a vial, a flexible bladder received within the vial, and a variable volume storage chamber formed between the bladder and vial. A filling valve is coupled in fluid communication with the storage chamber and defines (1) a normally closed, fluid-tight position hermetically sealing the storage chamber from the ambient atmosphere, and (2) an open position allowing the passage of fluid through the valve both to evacuate the storage chamber and to introduce fluid through the valve to fill the storage chamber. A pump is coupled in fluid communication with the storage chamber for pumping fluids out of the storage chamber. A dispensing valve is coupled in fluid communication with the pump and defines (1) a normally closed, fluid-tight position preventing the passage of fluid out of the dispenser, and (2) an open position for dispensing pumped fluid therethrough. The sealed, empty dispenser is sterilized, such as by applying gamma radiation thereto. Then, the sterilized, sealed, empty dispenser is filled with fluid by engaging the filling valve with an evacuating/dispensing member to evacuate the storage chamber, and by introducing fluid from the filling member through the open filling valve and into the storage chamber. The filling member is withdrawn from the valve, and a spring moves the valve to a closed position to hermetically seal the fluid within the dispenser.

    Abstract translation: 用于保持多个剂量的流体或其它物质并用于分配物质的分配器具有小瓶,容纳在小瓶内的柔性囊,以及形成在膀胱和小瓶之间的可变体积存储室。 填充阀与储存室流体连通地联接并且限定(1)将储存室与环境大气密封的常闭密封的流体密封位置,和(2)允许流体通过阀门的打开位置 两者都抽真空储存室并引入流体通过阀门填充储存室。 泵与储存室流体连通地联接,用于将流体泵出储存室。 分配阀与泵流体连通地联接并限定(1)常闭的,流体密封的位置,防止流体从分配器通过,以及(2)用于分配泵送的流体通过的打开位置。 密封的空分配器被灭菌,例如通过对其施加γ射线。 然后,通过使填充阀与排气/分配构件接合以消除储存室,并且通过将来自填充构件的流体通过打开的填充阀引入并进入储存室,灭菌的密封的空分配器充满流体。 填充构件从阀中取出,并且弹簧将阀移动到关闭位置以将分配器内的流体气密地密封。

    Medicament vial having a heat-sealable cap, and apparatus and method for filling the vial

    公开(公告)号:US06604561B2

    公开(公告)日:2003-08-12

    申请号:US09781846

    申请日:2001-02-12

    Applicant: Daniel Py

    Inventor: Daniel Py

    Abstract: A resealable cap for a medicament vial has a base portion formed of vulcanized rubber or like material known for providing a stable environment for the medicament contained within the vial, and a resealable portion overlying the base portion. The resealable portion is made of low-density polyethylene or like material, and can be punctured by a needle or like injection member for dispensing medicament into the vial. Prior to filling, the cap is assembled to the vial and the cap/vial assembly is sterilized. Then, a needle is inserted through the cap and medicament is introduced through the needle and into the vial. Upon withdrawal of the needle, the penetrated region of the cap is fused by laser or direct heat sealing to hermetically seal the needle hole in the cap.

    Cartridge for applying medicament to an eye from a dispenser
    368.
    再颁专利
    Cartridge for applying medicament to an eye from a dispenser 失效
    用于将药物从分配器施加到眼睛的药筒

    公开(公告)号:USRE37047E1

    公开(公告)日:2001-02-06

    申请号:US08567510

    申请日:1995-12-05

    Applicant: Daniel Py

    Inventor: Daniel Py

    CPC classification number: A61F9/0026 A61F9/0008 A61F2250/0067

    Abstract: A cartridge for actuating a piston-like or accordion-like dispenser-vial for applying medicament to an eye. The cartridge includes a housing for holding the dispenser-vial and a telescoping cylinder for compressing the dispenser-vial in the longitudinal direction to actuate the vial. The cartridge includes a locking mechanism for locking the telescoping cylinder to restrict its movement and a trigger mechanism for releasing the cylinder from the locked position so that a drop is released from the dispenser. The housing includes a finger for engaging the lower eyelid and exposing the conjunctival cul de sac.

    Abstract translation: 用于致动用于将药物施用于眼睛的活塞式或类风琴式分配器 - 小瓶的药筒。 该盒包括用于保持分配器 - 小瓶的壳体和用于在纵向方向上压缩分配器 - 小瓶以致动小瓶的伸缩圆柱体。 该卡盘包括用于锁定伸缩缸以限制其运动的锁定机构和用于将汽缸从锁定位置释放的触发机构,使得液滴从分配器释放。 外壳包括用于接合下眼睑并暴露结膜cul囊的手指。

    Double dispenser for medicinal liquids
    369.
    发明授权
    Double dispenser for medicinal liquids 失效
    双液体药液分配器

    公开(公告)号:US5875931A

    公开(公告)日:1999-03-02

    申请号:US661246

    申请日:1996-06-10

    Applicant: Daniel Py

    Inventor: Daniel Py

    CPC classification number: B05B11/3084 A61F9/0008

    Abstract: A double-dispenser system for dispensing medicinal liquids has two jet-trigger pumps housed in an outer casing having at least one front opening and one rear opening. Each jet-trigger pump is provided with a dosing mechanism for dispensing a predetermined dose of medicinal liquid. Dispensation from the two pumps may be triggered simultaneously by a trigger device common to the two pumps and accessible from the outside of the casing. The pumps incorporated in the double-dispenser system may be of the type having a pump body and a piston housed in an elastic bottle. For each pump, relative movements between the piston and the pump body causes changes in the relative-displacement between the piston and the pump body such that medicinal liquid is initially loaded into a medicine-holding cavity within the pump and subsequently dispensed.

    Abstract translation: 用于分配医用液体的双分配器系统具有容纳在具有至少一个前开口和一个后开口的外壳中的两个喷射触发泵。 每个喷射触发泵设置有用于分配预定剂量的药液的计量机构。 来自两个泵的分配可以由两个泵共用的触发装置同时触发并且可从壳体的外部进入。 结合在双分配器系统中的泵可以是具有容纳在弹性瓶中的泵体和活塞的类型。 对于每个泵,活塞和泵体之间的相对运动导致活塞和泵体之间的相对位移的变化,使得药用液体最初被装载到泵内的药物保持腔中并随后被分配。

    Apparatus for applying medicament to an eye
    370.
    发明授权
    Apparatus for applying medicament to an eye 失效
    用于将药物施用于眼睛的装置

    公开(公告)号:US5685869A

    公开(公告)日:1997-11-11

    申请号:US433856

    申请日:1995-05-02

    Applicant: Daniel Py

    Inventor: Daniel Py

    Abstract: An apparatus is used to apply medicament to an eye and stores the medicament in a medicament chamber. A nozzle is coupled in fluid communication with the medicament chamber and is formed by an outer nozzle portion and an inner nozzle portion received within the outer nozzle portion. A seam is formed by the interface of the inner nozzle portion and the outer nozzle portion and is normally in a closed position to prevent the passage of medicament through the nozzle. The seam opens in response to the flow of medicament of sufficient pressure into the seam to permit the passage of medicament through the nozzle for release into the eye.

    Abstract translation: 使用一种装置将药物施用于眼睛并将药物储存在药物室中。 喷嘴与药物室流体连通地连接并由外部喷嘴部分和容纳在外部喷嘴部分内部的内部喷嘴部分形成。 接缝由内部喷嘴部分和外部喷嘴部分的界面形成,并且通常处于关闭位置以防止药物通过喷嘴。 响应于足够压力的药物流进入接缝以使药物通过喷嘴以释放到眼睛中,接缝开口。

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