公开(公告)号：US09317664B2

公开(公告)日：2016-04-19

申请号：US10966041

申请日：2004-10-14

申请人： Sachin Ahuja ,  David Kita ,  Eniko Fodor ,  Adityo Prakash

发明人： Sachin Ahuja ,  David Kita ,  Eniko Fodor ,  Adityo Prakash

IPC分类号： G01N33/48 ,  G01N33/50 ,  G06F19/00 ,  G06F19/24 ,  G06F19/26 ,  G06F19/28 ,  G01N33/68 ,  G06F19/16 ,  C40B30/02 ,  G06F19/18

CPC分类号： G06F19/701 ,  C40B30/02 ,  G01N33/6803 ,  G06F19/16 ,  G06F19/18 ,  G06F19/24 ,  G06F19/26 ,  G06F19/28 ,  G06F19/706 ,  G06F19/707

摘要： A method for partitioning a molecular subset is described. The partitioning method takes into account molecular structure and its manner of storage and transmission, transformations to be applied to the molecular subset and their implementation, and constraints imposed by the implementation of the partitioning method. Using this method, a molecular subset can be stored, transmitted, and processed more efficiently. The resulting efficiency makes it possible to design and run applications which require complex molecular processing, such as rational drug discovery, virtual library design, etc.

摘要翻译： 描述了用于分割分子子集的方法。 分割方法考虑了分子结构及其存储和传输方式，应用于分子子集的变换及其实现，以及实施分区方法所施加的约束。 使用这种方法，可以更有效地存储，传输和处理分子子集。 所产生的效率使得可以设计和运行需要复杂的分子处理的应用，例如合理的药物发现，虚拟图书馆设计等。

公开(公告)号：US20160012194A1

公开(公告)日：2016-01-14

申请号：US14857034

申请日：2015-09-17

申请人： Adityo Prakash ,  Eniko Fodor

发明人： Adityo Prakash ,  Eniko Fodor

IPC分类号： G06F19/00

CPC分类号： G06Q30/0601 ,  G06F19/3456 ,  G06F19/3481 ,  G16H50/20

摘要： The present invention includes various embodiments of a BSA system that facilitates the collection of relevant health-related data on a continuous basis, integrates such data with pertinent personal and aggregate information, enables users to purchase (directly and indirectly) health-related goods and services, and provides credit, discounts and other economic benefits in connection with such purchases that are determined dynamically based upon the nature and extent of users' interaction with the system. The BSA system facilitates a dynamic feedback process by continually monitoring user interaction and medical and financial behavior, which results in dynamic adjustments to their credit levels and offers of discounts and other promotions, which in turn incentivizes users to continue participating in the process (thereby modifying their system interactions and behavior, and thus perpetuating this feedback loop). As a result, users are incentivized to actively participate in the process and thereby enhance their wellness while reducing healthcare costs.

摘要翻译： 本发明包括有助于持续收集相关健康相关数据的BSA系统的各种实施例，将这些数据与相关个人和聚合信息相结合，使用户能够（直接或间接地）购买与健康相关的商品和服务 并根据用户与系统的互动性质和程度，动态确定与此类购买相关的信用，折扣和其他经济利益。 BSA系统通过不断监视用户互动和医疗和金融行为，促进动态反馈过程，从而对其信用水平进行动态调整，并提供折扣和其他促销活动，从而激励用户继续参与该过程（从而修改 他们的系统相互作用和行为，从而使这个反馈循环永久化）。 因此，用户被激励积极参与过程，从而增强健康，同时降低医疗成本。

公开(公告)号：US07751988B2

公开(公告)日：2010-07-06

申请号：US10966341

申请日：2004-10-14

申请人： David Kita ,  Eniko Fodor ,  Adityo Prakash

发明人： David Kita ,  Eniko Fodor ,  Adityo Prakash

IPC分类号： G06F19/00 ,  G11C17/00

CPC分类号： G01N33/6803 ,  G01N2500/00 ,  G06F19/16 ,  G06F19/702

摘要： A method for the prediction of adverse cross-reactions between lead candidate biomolecules and potential reactant molecules, often biopolymers, is described. In a computational system, reactions are modeled within a suitable environment, in order to determine a reaction profile between a lead candidate molecule and a potential reactant molecule. A risk assessment is then generated for each lead based on a plurality of reaction profiles for the lead with respect to a plurality of potential reactant molecules. The method includes provisions for redesign and optimization of the lead candidate, possibly iterative in nature, in order to avoid predicted adverse cross-reactions.

摘要翻译： 描述了用于预测潜在候选生物分子与潜在的反应物分子（通常是生物聚合物）之间的不利交叉反应的方法。 在计算系统中，在合适的环境内对反应进行建模，以便确定主要候选分子和潜在的反应物分子之间的反应分布。 然后基于针对多个潜在的反应物分子的多个反应曲线，为每个引线产生风险评估。 该方法包括重新设计和优化主要候选人的条款，可能是迭代性质的，以避免预测的不利交叉反应。

公开(公告)号：US07133564B2

公开(公告)日：2006-11-07

申请号：US10087001

申请日：2002-02-28

申请人： Edward Ratner ,  Adityo Prakash ,  Hitoshi Watanabe ,  Sachin Ahuja

发明人： Edward Ratner ,  Adityo Prakash ,  Hitoshi Watanabe ,  Sachin Ahuja

IPC分类号： G06K9/36 ,  G06K9/48

CPC分类号： G06T7/12 ,  G06T2207/10016 ,  G06T2207/20008

摘要： One embodiment relates to an apparatus for image processing. The apparatus includes a candidate edge chain identifier for identifying candidate edge chains in an image being processed, means for calculating a dynamic chain-based threshold function that is dependent on at least one characteristic of the image being processed, and a threshold applicator for applying the dynamic chain-based threshold function to the candidate edge chains. The characteristic of the image being processed may be global in that it is determined from the overall image being processed. A system may include an encoder or a decoder, both of which include the above apparatus. Another embodiment relates to a method for image processing. The method determines a dynamic chain-based threshold function that is dependent on at least one characteristic of the image being processed and applies the dynamic threshold to a candidate edge chain.

公开(公告)号：US06978306B2

公开(公告)日：2005-12-20

申请号：US09927598

申请日：2001-08-09

申请人： Thomas D. Miller ,  Adityo Prakash ,  Hon Hing So ,  Kendall R. Haulotte

发明人： Thomas D. Miller ,  Adityo Prakash ,  Hon Hing So ,  Kendall R. Haulotte

IPC分类号： H04N7/173 ,  H04N21/2187 ,  H04N21/2225 ,  H04N21/231 ,  H04N21/24 ,  H04N21/258 ,  H04N21/266 ,  H04N21/472 ,  G06F15/173

CPC分类号： H04N21/2401 ,  H04N7/17336 ,  H04N21/2187 ,  H04N21/2225 ,  H04N21/23106 ,  H04N21/2402 ,  H04N21/25891 ,  H04N21/266 ,  H04N21/47202

摘要： A network for distributing broadband video content from its origination point to end users using a system of video servers, video storage devices, video caches and a broadband transmission network. Video material is initially received from content providers, encoded using a compression algorithm, and stored at a centralized location. Depending on the projected frequency of viewing of the content, it either remains stored at the centralized location for less frequently viewed content, or the projected frequently viewed content is proactively transmitted to storage systems located near the edge of the network close to the end users.

摘要翻译： 用于使用视频服务器，视频存储设备，视频缓存和宽带传输网络的系统将宽带视频内容从其始发点分发到终端用户的网络。 视频素材最初是从内容提供商接收的，使用压缩算法进行编码，并存储在集中的位置。 根据预计观看内容的频率，它或者保存在集中的位置，用于较不频繁观看的内容，或者将预计的经常观看的内容主动地发送到位于靠近终端用户的网络边缘附近的存储系统。

公开(公告)号：US06947605B2

公开(公告)日：2005-09-20

申请号：US10087463

申请日：2002-02-28

申请人： Adityo Prakash ,  Edward Ratner ,  Hitoshi Watanabe ,  Sachin Ahuja

发明人： Adityo Prakash ,  Edward Ratner ,  Hitoshi Watanabe ,  Sachin Ahuja

IPC分类号： G06T7/60 ,  G06T5/00 ,  G06T7/00 ,  G06K9/36

CPC分类号： G06T7/12 ,  G06T2207/10016 ,  G06T2207/20008

摘要： One embodiment relates to an apparatus for image processing. The apparatus includes a candidate edge chain identifier for identifying candidate edge chains in an image being processed, means for calculating a dynamic chain-based threshold function that is dependent on at least one characteristic of the image being processed, and a threshold applicator for applying the dynamic chain-based threshold function to the candidate edge chains. The characteristic of the image being processed may be local in that it is calculated from the vicinity of each candidate chain. A system may include an encoder or a decoder, both of which include the above apparatus. Another embodiment relates to a method for image processing. The method determines a dynamic chain-based threshold function that is dependent on at least one characteristic of the image being processed and applies the dynamic threshold to a candidate edge chain.

摘要翻译： 一个实施例涉及用于图像处理的装置。 所述装置包括候选边缘链标识符，用于识别正在处理的图像中的候选边缘链，用于计算取决于正被处理的图像的至少一个特征的基于动态链的阈值函数的装置，以及用于应用 基于动态链路阈值函数的候选边缘链。 正在处理的图像的特征可以是局部的，因为它是从每个候选链的附近计算的。 系统可以包括编码器或解码器，它们都包括上述装置。 另一实施例涉及一种用于图像处理的方法。 该方法确定依赖于正在处理的图像的至少一个特性的基于动态链的阈值函数，并将动态阈值应用于候选边缘链。

公开(公告)号：US20050156926A1

公开(公告)日：2005-07-21

申请号：US11081320

申请日：2005-03-16

申请人： Adityo Prakash ,  Eniko Fodor ,  Edward Ratner ,  David Cook

发明人： Adityo Prakash ,  Eniko Fodor ,  Edward Ratner ,  David Cook

IPC分类号： G06T7/60 ,  G06T7/00 ,  G06T7/20 ,  G06T15/40

CPC分类号： G06T7/579

摘要： In one embodiment according to the present invention, relative z-ordering of segments in a digital image is determined. A method comprises forward and backward motion matching of image regions to determine overlap, followed by the creation of relationships (e.g., pairwise relationships) between regions and comparing the result with the original image to determine the relative z-ordering.

摘要翻译： 在根据本发明的一个实施例中，确定数字图像中段的相对z-排列。 一种方法包括图像区域的向前和向后运动匹配以确定重叠，随后在区域之间建立关系（例如，成对关系），并将结果与​​原始图像进行比较以确定相对z排序。

公开(公告)号：US20050119837A1

公开(公告)日：2005-06-02

申请号：US10967085

申请日：2004-10-14

申请人： Adityo Prakash ,  David Kita ,  Eniko Fodor

发明人： Adityo Prakash ,  David Kita ,  Eniko Fodor

IPC分类号： G01N20060101 ,  G06F19/16 ,  G06F19/28 ,  G06F19/00

CPC分类号： G06F19/28 ,  G06F19/16

摘要： A method for the prediction of adverse cross-reactions between lead candidate biomolecules and potential reactant molecules, often biopolymers, is described. In a computational system, reactions are modeled within a suitable environment, in order to determine a reaction profile between a lead candidate molecule and a potential reactant molecule. A risk assessment is then generated for each lead based on a plurality of reaction profiles for the lead with respect to a plurality of potential reactant molecules. The method includes provision for the redesign and optimization of the lead candidate, possibly iterative in nature, in order to avoid predicted adverse cross-reactions.

摘要翻译： 描述了用于预测潜在候选生物分子与潜在的反应物分子（通常是生物聚合物）之间的不利交叉反应的方法。 在计算系统中，在合适的环境内对反应进行建模，以便确定主要候选分子和潜在的反应物分子之间的反应分布。 然后基于针对多个潜在的反应物分子的多个反应曲线，为每个引线产生风险评估。 该方法包括重新设计和优化主要候选人，可能是迭代的，以避免预测的不利交叉反应。

公开(公告)号：US20050119834A1

公开(公告)日：2005-06-02

申请号：US10966160

申请日：2004-10-14

申请人： David Kita ,  Somalee Datta ,  Adityo Prakash ,  Eniko Fodor

发明人： David Kita ,  Somalee Datta ,  Adityo Prakash ,  Eniko Fodor

IPC分类号： C12Q1/68 ,  G01N33/48 ,  G01N33/50 ,  G06F19/16 ,  G06F19/24 ,  G06F19/00

CPC分类号： G06F19/16 ,  G06F19/24 ,  G06F19/706

摘要： A method and apparatus for analysis of molecular combinations featuring two or more molecular subsets is described. The method computes the shape complementarity of the system utilizing a basis expansion representing molecular shapes of the first and second molecular subsets in a coordinate system. The precomputed sets of translated expansion coefficients for the first molecular subset are first constructed via application of a translation operator to a reference set of expansion coefficients and then stored on a computer recordable medium for later retrieval. Then a shape complementarity score, representing a correlation of the first and second molecular subsets, is computed via suitable application of rotation operators to both the stored translated expansion coefficients of the first molecular subset, and the reference expansion coefficients for the second molecular subset, over the sequence of different sampled configurations for the molecular combination. The application of a translation operator prior to one or more rotation operator(s) has significant and beneficial implications for hardware-based implementations of the method, embodiments of which in the context of a hardware apparatus will also be described.

摘要翻译： 描述用于分析具有两个或更多个分子子集的分子组合的方法和装置。 该方法利用表示坐标系中第一和第二分子子集的分子形状的基础扩展来计算系统的形状互补性。 首先通过将翻译算子应用于扩展系数的参考集合来构建用于第一分子子集的经翻译的扩展系数的预先计算的集合，然后存储在计算机可记录介质上用于稍后检索。 然后，表示第一和第二分子子集的相关性的形状互补评分通过将旋转算子适当地应用于第一分子子集的存储的翻译扩展系数和第二分子子集的参考扩增系数， 分子组合的不同采样配置的序列。 翻译运算符在一个或多个旋转运算符之前的应用对于该方法的基于硬件的实现具有显着和有益的影响，还将描述其硬件装置的上下文中的实施例。

公开(公告)号：US06898240B2

公开(公告)日：2005-05-24

申请号：US10094427

申请日：2002-03-07

申请人： Adityo Prakash ,  Eniko F. Prakash ,  Edward Ratner ,  John S. Chen

发明人： Adityo Prakash ,  Eniko F. Prakash ,  Edward Ratner ,  John S. Chen

IPC分类号： G06T7/20 ,  G06T9/00 ,  H04N7/26 ,  H04N7/12

CPC分类号： G06T7/20 ,  G06T9/00 ,  G06T9/004

摘要： One embodiment comprises a method for image processing. The method includes identifying an uncovered region in an image, determining at least one trivalent point, and extrapolating from the trivalent point to extend an edge of at least one of the image segments into the uncovered region. Another embodiment comprises an apparatus for image processing. The apparatus includes a predictor for predicting higher-frequency boundary information in newly uncovered regions. Another embodiment comprises a system for efficiently communicating video information. The system includes an encoder that encodes a video frame into an encoded frame, and a decoder that receives and decodes the encoded frame, wherein the encoder and decoder are both configured to identify uncovered regions and to extend edges from neighboring image segments into the uncovered region.

摘要翻译： 一个实施例包括用于图像处理的方法。 该方法包括识别图像中的未覆盖区域，确定至少一个三价点，并从三价点外推，将至少一个图像片段的边缘延伸到未覆盖区域。 另一实施例包括用于图像处理的装置。 该装置包括用于预测新近未覆盖区域中的较高频率边界信息的预测器。 另一实施例包括用于有效地传送视频信息的系统。 该系统包括将视频帧编码为编码帧的编码器和接收并解码编码帧的解码器，其中编码器和解码器都被配置为识别未覆盖区域并将边缘从相邻图像段延伸到未覆盖区域 。