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    ELECTRICAL LEAD FOR AN ELECTRONIC DEVICE SUCH AS AN IMPLANTABLE DEVICE
    31.
    发明申请
    ELECTRICAL LEAD FOR AN ELECTRONIC DEVICE SUCH AS AN IMPLANTABLE DEVICE 有权
    用于电子设备的电气引线，如可植入器件

    公开(公告)号：US20090254152A1

    公开(公告)日：2009-10-08

    申请号：US12478145

    申请日：2009-06-04

    Applicant: Ergin Atalar ,  Onur Ferhanoglu

    Inventor： Ergin Atalar ,  Onur Ferhanoglu

    IPC: A61N1/08

    CPC classification number: A61N1/08 ,  A61N1/05 ,  A61N1/086 ,  A61N1/3718

    Abstract: A lead for an electronic device which resists the induction of a current from an electromagnetic field external to said lead includes one or more pairs of adjacent segments of electrical wire, each of the pairs including a first segment of electrical wire and a second segment of electrical wire. The lead also includes one or more shielded RF chokes, wherein each of the shielded RF chokes is provided between the first segment of electrical wire and the second segment of electrical wire of a respective one of the one or more pairs of adjacent segments. Also, an implantable device that includes a generator for generating one or more electrical pulse and a lead as described for delivering the pulses to tissue within a patient's body. A method for making the described implantable device is also provided.

    Abstract translation: 用于抵抗从所述引线外部的电磁场感应电流的电子装置的引线包括一对或多对相邻的电线段，每对电极包括电线的第一段和电线的第二段 线。 引线还包括一个或多个屏蔽RF扼流圈，其中屏蔽RF扼流圈中的每一个被设置在电线的第一段和一对或多对相邻段之间相应的一对的电线的第二段之间。 而且，一种可植入装置，其包括用于产生一个或多个电脉冲的发生器和如所描述的用于将脉冲传送到患者体内的组织的引线。 还提供了制造所述可植入装置的方法。

    Device, systems and methods for localized heating of a vessel and/or in combination with MR/NMR imaging of the vessel and surrounding tissue
    32.
    发明授权
    Device, systems and methods for localized heating of a vessel and/or in combination with MR/NMR imaging of the vessel and surrounding tissue 失效
    用于容器局部加热和/或与容器和周围组织的MR / NMR成像组合的装置，系统和方法

    公开(公告)号：US07422568B2

    公开(公告)日：2008-09-09

    申请号：US10404903

    申请日：2003-04-01

    Applicant: Xiaoming Yang ,  Ergin Atalar ,  Christopher Yeung

    Inventor： Xiaoming Yang ,  Ergin Atalar ,  Christopher Yeung

    IPC: A61M31/00

    CPC classification number: A61B18/1492 ,  A61B2018/00404 ,  A61B2018/144 ,  A61B2090/374 ,  A61B2218/002

    Abstract: Featured are devices, systems and methods for localized heating of a vessel as well as devices, systems and methods for MR/NMR imaging of a vessel while locally heating a portion of the vessel. More particularly featured are such devices, systems and methods for use when administering or delivering therapeutic agents including genes and/or drugs to the tissues of the vessel. Such a method includes positioning a thermal energy delivery device proximal a target site with the vessel of a body and activating the thermal energy delivery device so as to heat the target site thereby locally increasing a temperature of tissue at the target site. In further embodiments, the method includes introducing a therapeutic medium to the target site over a predetermined time period, and wherein said activating occurs at least one of before, during or after said step of introducing.

    Abstract translation: 特征是用于容器的局部加热的装置，系统和方法以及用于容器的MR / NMR成像的装置，系统和方法，同时局部加热容器的一部分。 更特别的特征是这样的装置，系统和方法，用于在向血管的组织施用或递送包括基因和/或药物的治疗剂时使用。 这种方法包括将靶区域近端的热能输送装置与身体的容器定位，并激活热能递送装置，以便加热靶部位，从而局部增加靶部位的组织温度。 在另外的实施方案中，该方法包括在预定时间段内将治疗介质引入目标部位，并且其中所述激活发生在引入步骤之前，期间或之后的至少之一。

    MRI-GUIDED THERAPY METHODS AND RELATED SYSTEMS
    33.
    发明申请
    MRI-GUIDED THERAPY METHODS AND RELATED SYSTEMS 有权

    公开(公告)号：US20080058635A1

    公开(公告)日：2008-03-06

    申请号：US11924877

    申请日：2007-10-26

    Applicant: Henry Halperin ,  Ronald Berger ,  Ergin Atalar ,  Elliot McVeigh ,  Albert Lardo ,  Hugh Calkins ,  Joao Lima

    Inventor： Henry Halperin ,  Ronald Berger ,  Ergin Atalar ,  Elliot McVeigh ,  Albert Lardo ,  Hugh Calkins ,  Joao Lima

    IPC: A61B5/055 ,  A61B18/12

    CPC classification number: A61B5/055 ,  A61B5/415 ,  A61B5/418 ,  A61B18/1492 ,  A61B90/36 ,  A61B2017/00039 ,  A61B2017/00053 ,  A61B2090/374 ,  G01R33/285 ,  G01R33/34084 ,  G01R33/4808 ,  G01R33/5601

    Abstract: A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures. The invention is particularly applicable to catheter ablation, e.g., ablation of atrial fibrillation. In embodiments which are useful for catheter ablation, the combined electrophysiology and imaging antenna catheter may further include an ablation tip, and such embodiment may be used as an intracardiac device to both deliver energy to selected areas of tissue and visualize the resulting ablation lesions, thereby greatly simplifying production of continuous linear lesions. The invention further includes embodiments useful for guiding electrophysiologic diagnostic and therapeutic procedures other than ablation. Imaging of ablation lesions may be further enhanced by use of MR contrast agents. The antenna utilized in the combined electrophysiology and imaging catheter for receiving MR signals is preferably of the coaxial or “loopless” type. High-resolution images from the antenna may be combined with low-resolution images from surface coils of the MR scanner to produce a composite image. The invention further provides a system for eliminating the pickup of RF energy in which intracardiac wires are detuned by filtering so that they become very inefficient antennas. An RF filtering system is provided for suppressing the MR imaging signal while not attenuating the RF ablative current. Steering means may be provided for steering the invasive catheter under MR guidance. Other ablative methods can be used such as laser, ultrasound, and low temperatures.

    Steady state free precession based magnetic resonance thermometry
    35.
    发明申请
    Steady state free precession based magnetic resonance thermometry 有权
    基于稳态自由进动的磁共振测温

    公开(公告)号：US20050052183A1

    公开(公告)日：2005-03-10

    申请号：US10850450

    申请日：2004-05-21

    Applicant: Vaishali Paliwal ,  Abdel-Monem El-Sharkawy ,  Ergin Atalar

    Inventor： Vaishali Paliwal ,  Abdel-Monem El-Sharkawy ,  Ergin Atalar

    IPC: G01R33/48 ,  G01V3/00

    CPC classification number: G01R33/4804

    Abstract: Disclosed is a method and system for steady state free precession based magnetic resonance thermometry that measures changes in temperature on a pixel by pixel basis. The method comprises generating an RF pulse sequence used to find the proton resonance frequency shift, which is proportional to temperature change, processing the resultant MRI data to measure the proton frequency shift, and converting the measured proton frequency shift into change in temperature data. Further disclosed is a method for identifying and compensating for temperature drifts due to core heating of the gradient magnet.

    Abstract translation: 公开了一种用于基于逐个像素测量温度变化的基于稳态自由进动的磁共振测温法的方法和系统。 该方法包括产生用于找到与温度变化成比例的质子谐振频移的RF脉冲序列，处理所得到的MRI数据以测量质子频率偏移，并将测量的质子频移转换为温度数据变化。 进一步公开的是用于识别和补偿由于梯度磁体的核心加热引起的温度漂移的方法。

    Magnetic resonance RF coil assembly for imaging of the cervical region
    39.
    发明授权
    Magnetic resonance RF coil assembly for imaging of the cervical region 失效
    用于成像颈部区域的磁共振RF线圈组件

    公开(公告)号：US08554303B2

    公开(公告)日：2013-10-08

    申请号：US13086577

    申请日：2011-04-14

    Applicant: Ergin Atalar ,  Nikolay V. Visksenko

    Inventor： Ergin Atalar ,  Nikolay V. Visksenko

    IPC: A61B5/055

    CPC classification number: A61B5/055 ,  G01R33/34084

    Abstract: A radio-frequency (RF) coil for obtaining magnetic resonance data for imaging the cervical region of a patient has a loop coil contained in a housing of an applicator assembly that is adapted for placement against the cervix of the patient, and a loopless antenna contained in a tandem applicator of the assembly, that is adapted for intracorporeal placement in the cervix of the patient.

    Abstract translation: 用于获得用于对患者的颈部区域成像的磁共振数据的射频（RF）线圈具有包含在施加器组件的壳体中的环形线圈，其适于放置抵靠患者的子宫颈，并且包含无孔天线 在组件的串联施放器中，其适于体内放置在患者的子宫颈中。

    Electrical lead for an electronic device such as an implantable device
    40.
    发明授权
    Electrical lead for an electronic device such as an implantable device 有权

    公开(公告)号：US08380277B2

    公开(公告)日：2013-02-19

    申请号：US13099167

    申请日：2011-05-02

    Applicant: Ergin Atalar ,  Onur Ferhanoglu

    Inventor： Ergin Atalar ,  Onur Ferhanoglu

    IPC: A61B5/04

    CPC classification number: A61N1/08 ,  A61N1/05 ,  A61N1/086 ,  A61N1/3718

    Abstract: A lead for an electronic device which resists the induction of a current from an electromagnetic field external to said lead includes one or more pairs of adjacent segments of electrical wire, each of the pairs including a first segment of electrical wire and a second segment of electrical wire. The lead also includes one or more shielded RF chokes, wherein each of the shielded RF chokes is provided between the first segment of electrical wire and the second segment of electrical wire of a respective one of the one or more pairs of adjacent segments. Also, an implantable device that includes a generator for generating one or more electrical pulse and a lead as described for delivering the pulses to tissue within a patient's body. A method for making the described implantable device is also provided.

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