公开(公告)号：US09301705B2

公开(公告)日：2016-04-05

申请号：US13341266

申请日：2011-12-30

申请人： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliott R. McVeigh ,  Albert Lardo ,  Hugh Caikins ,  Joao Lima

发明人： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliott R. McVeigh ,  Albert Lardo ,  Hugh Caikins ,  Joao Lima

IPC分类号： A61B5/05 ,  A61B5/055 ,  A61B5/00 ,  A61B18/14 ,  A61B19/00 ,  G01R33/28 ,  G01R33/34 ,  A61B17/00 ,  G01R33/48 ,  G01R33/56

CPC分类号： A61B5/055 ,  A61B5/415 ,  A61B5/418 ,  A61B18/1492 ,  A61B90/36 ,  A61B2017/00039 ,  A61B2017/00053 ,  A61B2090/374 ,  G01R33/285 ,  G01R33/34084 ,  G01R33/4808 ,  G01R33/5601

摘要： A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures includes an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures, such as ablation of cardiac arrhythmias. The combined electrophysiology and imaging antenna catheter may further include an ablation tip, and be used as an intracardiac device to deliver energy to selected areas of tissue and visualize the resulting ablation lesions.

摘要翻译： 使用磁共振成像来提高电生理过程精度的系统和方法包括侵入性组合电生理学和成像天线导管，其包括用于接收磁共振信号的RF天线和用于接收电位的诊断电极。 组合的电生理学和成像天线导管与磁共振成像扫描仪组合使用以在电生理诊断或治疗过程（例如心律失常消融）中引导和提供可视化。 组合的电生理学和成像天线导管还可以包括消融尖端，并且用作心内装置以将能量传递到组织的选定区域并且可视化所得到的消融损伤。

公开(公告)号：US08977355B2

公开(公告)日：2015-03-10

申请号：US12707084

申请日：2010-02-17

申请人： Robert A. Stevenson ,  Warren S. Dabney ,  Robert Shawn Johnson ,  Holly Noelle Moschiano ,  Henry R. Halperin

发明人： Robert A. Stevenson ,  Warren S. Dabney ,  Robert Shawn Johnson ,  Holly Noelle Moschiano ,  Henry R. Halperin

IPC分类号： A61N1/05 ,  H03H1/00 ,  G01R33/28 ,  A61N1/37 ,  A61N1/08 ,  H03H7/01

CPC分类号： H03H1/00 ,  A61N1/05 ,  A61N1/086 ,  A61N1/37 ,  A61N1/3718 ,  G01R33/285 ,  G01R33/288 ,  H03H1/0007 ,  H03H7/0115 ,  H03H7/1766 ,  H03H2001/0092 ,  H03H2007/013

摘要： A bandstop filter having optimum component values is provided for a lead of an active implantable medical device (AIMD). The bandstop filter includes a capacitor in parallel with an inductor. The parallel capacitor and inductor are placed in series with the implantable lead of the AIMD, wherein values of capacitance and inductance are selected such that the bandstop filter is resonant at a selected frequency. The Q of the inductor may be relatively maximized and the Q of the capacitor may be relatively minimized to reduce the overall Q of the bandstop filter to attenuate current flow through the implantable lead along a range of selected frequencies.

摘要翻译： 为有源可植入医疗装置（AIMD）的引线提供具有最佳分量值的带阻滤波器。 带阻滤波器包括与电感器并联的电容器。 并联电容器和电感器与AIMD的可植入引线串联放置，其中选择电容和电感值，使得带阻滤波器以选定的频率谐振。 电感器的Q可以相对最大化，并且电容器的Q可以相对最小化，以减小带阻滤波器的总体Q，以衰减沿着所选择的频率范围通过可植入引线的电流。

公开(公告)号：US20120188027A1

公开(公告)日：2012-07-26

申请号：US13440382

申请日：2012-04-05

申请人： Henry R. Halperin ,  Robert A. Stevenson

发明人： Henry R. Halperin ,  Robert A. Stevenson

IPC分类号： H03H7/01

CPC分类号： A61N1/08 ,  A61B18/1492 ,  A61B2018/00839 ,  A61B2090/374 ,  A61N1/05 ,  A61N1/086 ,  A61N1/37 ,  A61N1/3718 ,  G01R33/285 ,  G01R33/287 ,  G01R33/288 ,  H03H1/0007 ,  H03H7/1766 ,  H03H2007/013 ,  Y10T29/49169

摘要： A band stop filter is provided for a lead wire of an active medical device (AMD). The band stop filter includes a capacitor in parallel with an inductor. The parallel capacitor and inductor are placed in series with the lead wire of the AMD, wherein values of capacitance and inductance are selected such that the band stop filter is resonant at a selected frequency. The Q of the inductor may be relatively maximized and the Q of the capacitor may be relatively minimized to reduce the overall Q of the band stop filter to attenuate current flow through the lead wire along a range of selected frequencies. In a preferred form, the band stop filter is integrated into a TIP and/or RING electrode for an active implantable medical device.

摘要翻译： 为有源医疗装置（AMD）的引线提供带阻滤波器。 带阻滤波器包括与电感并联的电容器。 并联电容器和电感器与AMD的引线串联放置，其中选择电容和电感值，使得带阻滤波器以选定的频率谐振。 电感器的Q可以相对最大化，并且电容器的Q可以相对最小化，以减小带阻滤波器的总体Q，以衰减沿着选定频率的范围通过引线的电流。 在优选形式中，带阻滤波器被集成到用于有源可植入医疗装置的TIP和/或RING电极中。

公开(公告)号：US08200342B2

公开(公告)日：2012-06-12

申请号：US12850870

申请日：2010-08-05

申请人： Robert A. Stevenson ,  Buehl E. Truex ,  Barry C. Muffoletto ,  Warren S. Dabney ,  Christine A. Frysz ,  Christopher Michael Williams ,  Holly Noelle Moschiano ,  Jeff Fleigle ,  Kishore Kumar Kondabatni ,  Richard L. Brendel ,  Robert Shawn Johnson ,  Scott Brainard ,  Henry R. Halperin ,  Albert C. Lardo

发明人： Robert A. Stevenson ,  Buehl E. Truex ,  Barry C. Muffoletto ,  Warren S. Dabney ,  Christine A. Frysz ,  Christopher Michael Williams ,  Holly Noelle Moschiano ,  Jeff Fleigle ,  Kishore Kumar Kondabatni ,  Richard L. Brendel ,  Robert Shawn Johnson ,  Scott Brainard ,  Henry R. Halperin ,  Albert C. Lardo

IPC分类号： A61N1/08

CPC分类号： A61N1/05 ,  A61B5/042 ,  A61B5/055 ,  A61B90/98 ,  A61B2018/00839 ,  A61B2090/374 ,  A61N1/086 ,  A61N1/3718 ,  B82Y30/00 ,  G01R33/285

摘要： An energy management system facilitates the transfer of high frequency energy coupled into an implanted abandoned lead at a selected RF frequency or frequency band, to an energy dissipating surface. This is accomplished by conductively coupling the implanted abandoned lead to the energy dissipating surface of an abandoned lead cap through an energy diversion circuit including one or more passive electronic network components whose impedance characteristics are at least partially tuned to the implanted abandoned lead's impedance characteristics.

摘要翻译： 能量管理系统有助于将以选定的RF频率或频带耦合到植入的废弃引线中的高频能量传送到能量消散表面。 这是通过将植入的废弃导线导电地耦合到废弃的引线帽的能量消散表面，通过包括一个或多个无源电子网络部件的能量转向电路实现的，该无源电子网络部件的阻抗特性至少部分地被调整到被植入的废弃引线的阻抗特性。

公开(公告)号：US08147433B2

公开(公告)日：2012-04-03

申请号：US11676152

申请日：2007-02-16

申请人： Henry R. Halperin ,  Ronald D. Berger

发明人： Henry R. Halperin ,  Ronald D. Berger

IPC分类号： A61H31/00

CPC分类号： A61H31/005 ,  A61B5/0205 ,  A61B5/04017 ,  A61B5/0402 ,  A61B5/11 ,  A61B5/1135 ,  A61B5/4836 ,  A61B5/6825 ,  A61B5/6831 ,  A61B5/721 ,  A61B5/725 ,  A61B5/7257 ,  A61B5/742 ,  A61B2562/0219 ,  A61H31/00 ,  A61H31/006 ,  A61H31/007 ,  A61H2201/5007 ,  A61H2201/5048 ,  A61H2201/5058 ,  A61H2201/5064 ,  A61H2201/5071 ,  A61H2201/5084 ,  A61H2230/04 ,  A61H2230/06 ,  A61H2230/855 ,  A61M16/00 ,  A61M16/10 ,  A61M2230/06 ,  A61N1/39 ,  G06F19/00 ,  G06K9/0051 ,  G09B23/288

摘要： A chest compressions monitor for measuring the depth of chest compressions achieved during CPR. A displacement detector produces a displacement indicative signal indicative of the displacement of the CPR recipient's chest toward the recipient's spine. A signaling mechanism provides chest compression indication signals directing a chest compression force being applied to the chest and a frequency of such compressions.

摘要翻译： 用于测量CPR期间胸部按压深度的胸部按压监护仪。 位移检测器产生指示CPR接收者的胸部朝向受体的脊柱的位移的位移指示信号。 信号机构提供胸部压缩指示信号，其指示施加到胸部的胸部压缩力和这种按压的频率。

公开(公告)号：US08145324B1

公开(公告)日：2012-03-27

申请号：US13276195

申请日：2011-10-18

申请人： Robert A. Stevenson ,  Henry R. Halperin ,  Albert C. Lardo ,  Warren S. Dabney ,  Kishore Kumar Kondabatni ,  Christine A. Frysz ,  Robert Shawn Johnson ,  Holly Noelle Moschiano

发明人： Robert A. Stevenson ,  Henry R. Halperin ,  Albert C. Lardo ,  Warren S. Dabney ,  Kishore Kumar Kondabatni ,  Christine A. Frysz ,  Robert Shawn Johnson ,  Holly Noelle Moschiano

IPC分类号： A61N1/00

CPC分类号： A61N1/05 ,  A61N1/0529 ,  A61N1/0556 ,  A61N1/086 ,  H03H1/0007 ,  H03H7/0115 ,  H03H2001/0085 ,  H03H2007/013

摘要： A medical lead system includes at least one bandstop filter for attenuating current flow through the lead across a range of frequencies. The bandstop filter has an overall circuit Q wherein the resultant 3 dB bandwidth is at least 10 kHz. The values of capacitance and inductance of the bandstop filter are selected such that the bandstop filter is resonant at a selected center frequency or range of frequencies. Preferably, the bandstop filter has an overall circuit Q wherein the resultant 10 dB bandwidth is at least 10 kHz. Such bandstop filters are backwards compatible with known implantable deployment systems and extraction systems.

摘要翻译： 医疗引线系统包括至少一个带阻滤波器，用于在一定频率范围内衰减通过引线的电流。 带阻滤波器具有总电路Q，其中所得的3dB带宽至少为10kHz。 选择带阻滤波器的电容和电感值，使得带阻滤波器在选定的中心频率或频率范围内谐振。 优选地，带阻滤波器具有总电路Q，其中所得的10dB带宽至少为10kHz。 这种带阻滤波器与已知的可植入部署系统和提取系统向后兼容。

公开(公告)号：US20120053667A1

公开(公告)日：2012-03-01

申请号：US13275740

申请日：2011-10-18

申请人： Robert A. Stevenson ,  Henry R. Halperin ,  Albert C. Lardo

发明人： Robert A. Stevenson ,  Henry R. Halperin ,  Albert C. Lardo

IPC分类号： A61N1/05

CPC分类号： A61N1/08 ,  A61B18/1492 ,  A61B2018/00839 ,  A61B2090/374 ,  A61N1/05 ,  A61N1/086 ,  A61N1/37 ,  A61N1/3718 ,  G01R33/285 ,  G01R33/287 ,  G01R33/288 ,  H03H1/0007 ,  H03H7/1766 ,  H03H2007/013 ,  Y10T29/49169

摘要： A bandstop filter includes a capacitance in parallel with an inductance and is placed in series with the implantable lead of an active implantable medical device, wherein values of capacitance and inductance are selected such that the bandstop filter attenuates RF current flow at a selected center MRI RF pulsed frequency or across a range of frequencies. The Qi of the inductor and the Qc of the capacitor are controlled to reduce the overall Q of the bandstop filter to attenuate current flow through the implantable lead along a range of selected frequencies. In a preferred form, the bandstop filter is integrated into a Tip and/or Ring electrode for the active implantable medical device.

摘要翻译： 带阻滤波器包括与电感并联的电容，并且与有源可植入医疗装置的可植入引线串联放置，其中选择电容和电感值，使得带阻滤波器衰减所选择的中心MRI RF处的RF电流 脉冲频率或频率范围。 控制电感器的Q i和电容器的Qc以减小带阻滤波器的总体Q，以衰减沿可选择的频率范围通过可植入引线的电流。 在优选形式中，带阻滤波器被集成到用于有源可植入医疗装置的尖端和/或环形电极中。

公开(公告)号：US20120016179A1

公开(公告)日：2012-01-19

申请号：US13182800

申请日：2011-07-14

申请人： Norman PARADIS ,  David BARASH ,  Henry R. HALPERIN ,  Gary FREEMAN

发明人： Norman PARADIS ,  David BARASH ,  Henry R. HALPERIN ,  Gary FREEMAN

IPC分类号： A61N1/365 ,  A61H31/02 ,  A61M1/12 ,  A61N5/00 ,  A61H31/00 ,  A61N1/39

CPC分类号： A61H31/006 ,  A61H9/0078 ,  A61H31/005 ,  A61H2201/5007 ,  A61H2201/5097 ,  A61H2230/00 ,  A61H2230/045 ,  A61M16/00 ,  A61M16/0003 ,  A61M16/0057 ,  A61M16/0063 ,  A61M16/024 ,  A61M2205/33 ,  A61M2205/332 ,  A61M2205/581 ,  A61M2205/583 ,  A61M2230/04 ,  A61M2230/202 ,  A61M2230/30 ,  A61N1/3987

摘要： A method for improving the cardiac output of a patient who is suffering from pulseless electrical activity or shock and yet still displays some myocardial wall motion including sensing myocardial activity to determine the presence of residual left ventricular pump function having a contraction or ejection phase and a filling or relaxation phase. In such cases, a compressive force is repeatedly applied to the chest based on the sensed myocardial activity such that the compressive force is applied during at least some of the ejection phases and is ceased during at least some of the relaxation phases to permit residual cardiac filling, thereby enhancing cardiac output and organ perfusion. Also incorporated may be a logic circuit capable of utilizing multiple sensing modalities and optimizing the synchronization pattern between multiple phasic therapeutic modalities and myocardial residual mechanical function.

摘要翻译： 一种用于改善患有无脉动电活动或休克的患者的心输出量并且还显示一些心肌壁运动的方法，包括感测心肌活动以确定具有收缩或排出期的残留左心室泵功能的存在和填充 或弛豫阶段。 在这种情况下，基于所感测到的心肌活动，将压缩力重复施加到胸部，使得在至少一些喷射阶段期间施加压缩力，并且在至少一些松弛阶段期间停止压缩力，以允许残留的心脏填充 ，从而增强心输出量和器官灌注。 还可并入的是可以利用多个感测模式并优化多阶段性治疗方式与心肌残留机械功能之间的同步模式的逻辑电路。

公开(公告)号：US08096962B2

公开(公告)日：2012-01-17

申请号：US11472149

申请日：2006-06-20

申请人： James Adam Palazzolo ,  Ronald D. Berger ,  Henry R. Halperin ,  Darren R. Sherman

发明人： James Adam Palazzolo ,  Ronald D. Berger ,  Henry R. Halperin ,  Darren R. Sherman

IPC分类号： A61H31/00 ,  A61B5/0402

CPC分类号： A61H31/005 ,  A61B5/04012 ,  A61B5/044 ,  A61B5/053 ,  A61B5/0535 ,  A61B5/721 ,  A61B5/7242 ,  A61B5/725 ,  A61H31/006 ,  A61H31/007 ,  A61H31/008 ,  A61H2201/5007 ,  A61H2201/501 ,  A61H2201/5012 ,  A61H2201/5043 ,  A61H2201/5048 ,  A61H2201/5058 ,  A61H2201/5084 ,  A61H2201/5097 ,  A61H2230/04 ,  A61H2230/08 ,  A61H2230/40 ,  A61M16/00 ,  A61M16/0078 ,  A61N1/39 ,  G06K9/0051 ,  Y10S128/901 ,  Y10S601/08 ,  Y10S601/09 ,  Y10S601/10

摘要： A method of processing a raw acceleration signal, measured by an accelerometer-based compression monitor, to produce an accurate and precise estimated actual depth of chest compressions. The raw acceleration signal is filtered during integration and then a moving average of past starting points estimates the actual current starting point. An estimated actual peak of the compression is then determined in a similar fashion. The estimated actual starting point is subtracted from the estimated actual peak to calculate the estimated actual depth of chest compressions. In addition, one or more reference sensors (such as an ECG noise sensor) may be used to help establish the starting points of compressions. The reference sensors may be used, either alone or in combination with other signal processing techniques, to enhance the accuracy and precision of the estimated actual depth of compressions.

摘要翻译： 一种处理通过基于加速度计的压缩监视器测量的原始加速度信号的方法，以产生精确和准确的估计的胸部按压实际深度。 原始加速度信号在积分过程中被过滤，然后过去起点的移动平均值估计实际的当前起始点。 然后以类似的方式确定压缩的估计实际峰值。 从估计的实际峰值中减去估计的实际起点，以计算胸部按压的估计实际深度。 此外，可以使用一个或多个参考传感器（例如ECG噪声传感器）来帮助建立压缩的起始点。 参考传感器可以单独使用或与其他信号处理技术组合使用，以增强估计的实际深度压缩的精度和精度。

公开(公告)号：US20110306860A1

公开(公告)日：2011-12-15

申请号：US13215722

申请日：2011-08-23

申请人： Henry R. Halperin ,  Robert A. Stevenson

发明人： Henry R. Halperin ,  Robert A. Stevenson

IPC分类号： A61B5/04 ,  H01R43/00 ,  A61N1/08

CPC分类号： A61N1/08 ,  A61B18/1492 ,  A61B2018/00839 ,  A61B2090/374 ,  A61N1/05 ,  A61N1/086 ,  A61N1/37 ,  A61N1/3718 ,  G01R33/285 ,  G01R33/287 ,  G01R33/288 ,  H03H1/0007 ,  H03H7/1766 ,  H03H2007/013 ,  Y10T29/49169

摘要： A band stop filter is provided for a lead wire of an active medical device (AMD). The band stop filter includes a capacitor in parallel with an inductor. The parallel capacitor and inductor are placed in series with the lead wire of the AMD, wherein values of capacitance and inductance are selected such that the band stop filter is resonant at a selected frequency. The Q of the inductor may be relatively maximized and the Q of the capacitor may be relatively minimized to reduce the overall Q of the band stop filter to attenuate current flow through the lead wire along a range of selected frequencies. In a preferred form, the band stop filter is integrated into a TIP and/or RING electrode for an active implantable medical device.

摘要翻译： 为有源医疗装置（AMD）的引线提供带阻滤波器。 带阻滤波器包括与电感并联的电容器。 并联电容器和电感器与AMD的引线串联放置，其中选择电容和电感值，使得阻带滤波器以选定的频率谐振。 电感器的Q可以相对最大化，并且电容器的Q可以相对最小化，以减小带阻滤波器的总体Q，以衰减沿着选定频率的范围通过引线的电流。 在优选形式中，带阻滤波器被集成到用于有源可植入医疗装置的TIP和/或RING电极中。