Abstract:
This invention relates to novel pharmaceutically-useful compounds, to methods for their preparation, and to pharmaceutical compositions and therapeutic methods for treating certain conditions.
Abstract:
A novel computational QSAR approach that provides sub-molecular correlations that are specific to individual lobes of the pertinent molecular orbitals.
Abstract:
The present invention relates to novel pharmaceutically-useful compounds which are antagonists of the 5-oxo-ETE receptors, such as the OXE receptor. These compounds have use as therapeutic and/or prophylactic agents for diseases characterized by tissue eosinophilia, such as inflammatory conditions including respiratory diseases. The invention also relates to pharmaceutical compositions, to the use of such compounds and compositions as medicaments, and to therapeutic methods.
Abstract:
A multiplexed optical communication system comprising a carrier optical fiber, a plurality of launching light sources, and a matching plurality of multiplexer/demultiplexers and photodetectors is described and claimed. Optical communication channel separation by Spatial Domain Multiplexing (SDM), Optical Angular Momentum (OAM) multiplexing, and Wavelength Division Multiplexing (WDM) is used in combination to achieve significant increase in optical communication channel bandwidth over the prior art. The launching light sources may be positioned such that the light beams are incident on the receiving end of the carrier optical fiber at desired angles including complementary angles. Crosstalk between optical communication channels is minimal. The communication bandwidth of a TDM system may be increased by an order of magnitude due the layered WDM/SDM/OAM data multiplexing of the invention.
Abstract:
A free space optical receiver comprising a photodetector and a fiber bundle. The fiber bundle comprises a plurality of optical fibers splayed apart at one of their ends to receive free space optical energy from multiple directions. The splayed apart ends of the plurality of optical fibers may create a hemispherical shape. Each of the plurality of optical fibers has an acceptance cone for which it couples optical energy into the splayed end of the optical fiber. The acceptance cones of the splayed ends of the plurality of optical fibers may overlap to form an omnidirectional acceptance zone. The other, non-splayed ends of the plurality of optical fibers are communicatively coupled to the photodetector, which is positioned to receive the free space optical energy from the non-splayed ends of the plurality of optical fibers. An optical communication system including the free space optical receiver is also described.
Abstract:
This invention combines novel materials to provide improved fluid dynamic, biofouling and corrosion control to structures, for example ship stabilizer fins, by applying a novel multilayered conformal covering to such structures. The covering may further comprise drag-reducing control surfaces such as grooves, crests and troughs that improve the hydrodynamic characteristics of the structure. The invention may be comprised of two layers: an inner layer comprising an fabric, composite, elastomeric, or combination thereof, material to provide shape and a firm fit to the existing body and an outer layer comprising silicone based polymer to prevent or control biological growth. The properties of the inner layer, which may be stiff or elastomeric, are selected to provide a tough conformal fit over the structure to be improved and may be made from an fabric, composite or elastomer, or combinations thereof, such as neoprene or high modulus toughened silicone.