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公开(公告)号:US20230142770A1
公开(公告)日:2023-05-11
申请号:US18151004
申请日:2023-01-06
Applicant: GALVANI BIOELECTRONICS LIMITED , Université Côte d 'Azur , CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE
Inventor: Philippe Blancou , Nicolas GLAICHENHAUS , Arun SRIDHAR
IPC: A61N1/36
CPC classification number: A61N1/36139 , A61N1/36007 , A61N1/36157 , A61N1/36171 , A61N1/37211
Abstract: Devices and methods for the stimulation of neural signalling of an apical splenic nerve, the device having a transducer for placement on or around the apical splenic nerve, and a signal generator to generate a signal that stimulates or inhibits the neural activity of the apical splenic nerve to produce a physiological response. The transducer has at least one electrode, and the signal generator is a voltage or current source. The stimulation electrical signal has a frequency of between 1 Hz and 50 Hz.
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公开(公告)号:US20230125962A1
公开(公告)日:2023-04-27
申请号:US18145780
申请日:2022-12-22
Applicant: GALVANI BIOELECTRONICS LIMITED
Inventor: Faisal ZAIDI , Sebastien OUCHOUCHE
Abstract: An extravascular neural interface is disclosed containing electrodes for neurostimulation of the vessel. The devices are housed in flexible substrates, each substrate having a spinal portion for routing leads/conductors into the device for connection to the electrodes. Extending from opposite sides of the spinal portion is a self-sizing inner flap that supports and positions the electrodes to be inward facing, i.e., extravascular designs, and one more rigid outer flap. The electrodes may be flexible multifilar coil electrodes.
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公开(公告)号:US20230041002A1
公开(公告)日:2023-02-09
申请号:US17769620
申请日:2020-10-15
Applicant: Galvani Bioelectronics Limited
Inventor: Morten Hansen , Jay Canham
Abstract: A belt-like garment is disclosed herein that addresses the need in the wireless recharging field for a holder that maintains the proximity of the recharger to the implanted device, is less bulky and better conforming to the wearer, is easy to don and doff, and prevents shifting throughout the recharging session.
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公开(公告)号:US20230017399A1
公开(公告)日:2023-01-19
申请号:US17883332
申请日:2022-08-08
Inventor: Alessandra Giarola , Yee-Hsee Hsieh , Stephen J. Lewis , Arun Sridhar
Abstract: This disclosure provides an apparatus or system for the modulation of neural activity in the cervical sympathetic chain (CSC) or superior cervical ganglion (SCG) or SCG post-ganglionic branch(es) and for the treatment of sleep apnoea, as well as methods for their use.
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公开(公告)号:US20230010306A1
公开(公告)日:2023-01-12
申请号:US17785374
申请日:2020-12-15
Applicant: Galvani Bioelectronics Limited
Inventor: Rizwan Bashirullah , Gerald Edwin Hunsberger
Abstract: A stent for intravascular stimulation comprises a scaffold comprising first and second scaffold structures, each scaffold structure comprising at least one substantially annular portion. The stent further comprises one or more anodal electrodes formed from or electrically coupled to at least a substantially annular portion of the first scaffold structure and one or more cathodal electrodes electrically formed from or coupled to at least a substantially annular portion of the second scaffold structure. The stent further comprises an anodal lead electrically coupled to the first scaffold structure to form a conductive path from the one or more anodal electrodes to a generator and a cathodal lead electrically coupled to the second scaffold structure to form a conductive path from the one or more cathodal electrodes to the generator. The stent further comprises a sleeve of insulating material, wherein the scaffold structures are attached to or formed on the sleeve of insulating material and are separated from each other by a distance such that the first and second scaffold structures are electrically insulated from each other.
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公开(公告)号:US20230009490A1
公开(公告)日:2023-01-12
申请号:US17780214
申请日:2020-11-27
Applicant: Galvani Bioelectronics Limited
Inventor: Sebastien Ouchouche , Cindy Au , Kenneth Douglas Rys , Thomas Burge
IPC: A61N1/05
Abstract: An implantable neural interface system comprising: at least one electrode; a spine providing a passage for electrical conductors connectable to a pulse generator and the at least one electrode; at least one arm extending from the spine, wherein the electrode is positioned on the arm; and a strain relief feature configured to reduce strain in relative movement of portions of neural interface system to accommodate a curvature in an axis of a target on or in which the neural interface is provided.
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公开(公告)号:US20220409888A1
公开(公告)日:2022-12-29
申请号:US17780195
申请日:2020-11-27
Applicant: Galvani Bioelectronics Limited
Inventor: Sebastien Ouchouche , David Karl Lee Peterson , Eric Irwin , Robert W. Coatney , Benjamin Yaffe , Morten Hansen , Faisal Zaidi , Thomas Burge , Pey-Jiun Ko , Cindy Au , Paul Matteucci , Mark Gregory Palmer , Gerald Edwin Hunsberger
IPC: A61N1/05
Abstract: In embodiments a neural interface comprising at least one C-ring portion can be used to apply a pressure in a range of 0 mmHg to 30 mmHg to a target tissue arranged within the C-ring portion and comprising at least one electrode arranged on the at least one C-ring portion.
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公开(公告)号:US11464978B2
公开(公告)日:2022-10-11
申请号:US16955345
申请日:2018-12-20
Applicant: GALVANI BIOELECTRONICS LIMITED
Inventor: Daniel John Chew , Matteo Donega , Isha Gupta
Abstract: Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging and shock.
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公开(公告)号:US20220249840A1
公开(公告)日:2022-08-11
申请号:US17619215
申请日:2020-06-17
Applicant: Galvani Bioelectronics Limited
Inventor: Isha Gupta , Matteo Donega
Abstract: Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging, shock, acute respiratory distress syndrome (ARDS), severe respiratory distress syndrome (SARS), and coronavirus disease 19 (COVID-19).
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公开(公告)号:US11357976B2
公开(公告)日:2022-06-14
申请号:US16634632
申请日:2018-07-23
Applicant: GALVANI BIOELECTRONICS LIMITED
Inventor: Faisal Zaidi , Sebastien Ouchouche
Abstract: An extravascular neural interface is disclosed including a device containing electrodes for neurostimulation of a vessel. The devices are housed in flexible substrates forming two flaps, an inner flap having a spinal portion for routing leads/conductors into the device for connection to the electrodes and an outer flap that overlaps the inner flap. The inner flap supports and positions the electrodes to be inward facing, i.e., extravascular designs. The electrodes may be circular or elliptical and include a plurality of wings for securing the electrodes within a flap.
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