公开(公告)号：US20110264196A1

公开(公告)日：2011-10-27

申请号：US13093305

申请日：2011-04-25

Applicant: Padraig Savage ,  Gianfranco Pellegrini ,  Finn Rinne ,  Matthew Rust ,  Michael Krivoruchko

Inventor： Padraig Savage ,  Gianfranco Pellegrini ,  Finn Rinne ,  Matthew Rust ,  Michael Krivoruchko

IPC: A61F2/82 ,  A61F2/24

CPC classification number: A61F2/24 ,  A61F2/2418 ,  A61F2/848 ,  A61F2002/8483 ,  A61F2220/0016 ,  A61F2230/0054 ,  A61F2230/008

Abstract: A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.

Abstract translation: 一种支架式阀，包括具有大致管状主体部分，内部区域，纵向轴线，第一端部，第二端部和外部表面的支架结构; 至少一个流出倒钩，其从所述支架的外表面邻近所述支架结构的所述第一端延伸并朝向所述支架结构的第二端; 至少一个流入倒钩，其从所述支架的外表面延伸到所述支架结构的第二端并朝向所述支架结构的第一端; 以及附接在支架结构的内部区域内的阀结构。

公开(公告)号：US20070250152A1

公开(公告)日：2007-10-25

申请号：US11379629

申请日：2006-04-21

Applicant: Jia Xiao ,  Matthew Rust

Inventor： Jia Xiao ,  Matthew Rust

IPC: A61F2/06

CPC classification number: A61F2/07 ,  A61F2/064 ,  A61F2/89 ,  A61F2002/061 ,  A61F2250/006

Abstract: A stent-graft includes a short tube graft and patch located inside of a primary graft. The patch forms a smooth and reliably sealed transition between the primary graft and the short tube graft. Accordingly, the disruption to fluid, e.g., blood, flowing through the lumen of the primary graft by the short tube graft is minimal. Further, the patch supports the inner end of the short tube graft. Thus, the patch, the short tube graft and the primary graft form a stable three-dimensional structure.

Abstract translation: 支架移植物包括位于主移植物内部的短管移植物和补片。 贴片在主移植物和短管移植物之间形成平滑且可靠的密封过渡。 因此，通过短管移植物流过主移植物的内腔的流体例如血液的破裂是最小的。 此外，贴片支撑短管移植物的内端。 因此，贴剂，短管移植物和原始移植物形成稳定的三维结构。

公开(公告)号：US20070239252A1

公开(公告)日：2007-10-11

申请号：US11279206

申请日：2006-04-10

Applicant: Darren Hopkins ,  Jack Chu ,  Jonathan Morris ,  James Machek ,  Prema Ganesan ,  Matthew Rust ,  Trevor Greenan ,  James Moriarty

Inventor： Darren Hopkins ,  Jack Chu ,  Jonathan Morris ,  James Machek ,  Prema Ganesan ,  Matthew Rust ,  Trevor Greenan ,  James Moriarty

IPC: A61F2/06

CPC classification number: A61F2/95 ,  A61F2002/821 ,  A61F2250/0039

Abstract: A method of using a delivery system includes advancing a stent to be located within an ostium of a vessel; advancing a basket actuation button of a handle to deploy a basket of the basket assembly; moving the basket into engagement with a parent vessel, the basket having a larger diameter than a diameter of the ostium; deploying the stent within an ostial lesion of the vessel; and contracting the basket.

Abstract translation: 使用输送系统的方法包括推进位于血管口内的支架; 推动手柄的篮子致动按钮以部署一篮篮组件; 将篮子移动到与父母船只接合，篮子具有比口的直径更大的直径; 将支架部署在血管的口腔损伤中; 并承包篮子。

公开(公告)号：US20070203565A1

公开(公告)日：2007-08-30

申请号：US11464036

申请日：2006-08-11

Applicant: Matthew Rust ,  Prema Ganesan ,  Curtis Hanson ,  Jack Chu

Inventor： Matthew Rust ,  Prema Ganesan ,  Curtis Hanson ,  Jack Chu

IPC: A61F2/06 ,  A61F2/94

CPC classification number: A61F2/07 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12118 ,  A61B17/12131 ,  A61B17/3403 ,  A61B2017/00252 ,  A61F2/06 ,  A61F2/064 ,  A61F2/89 ,  A61F2002/061 ,  A61F2002/072

Abstract: The invention provides a method of providing an endovascular bypass. The method includes the steps of inserting an elastic needle carrying a guidewire adjacent an ostium via a catheter and extending the needle through a branch vessel wall. The method continues by extending the needle through the extravascular space and inserting the needle through a main vessel wall to create an opening. The needle is retracted, leaving the guidewire in place. A bypass stent graft is inserted along the guidewire to provide a pathway between the branch vessel and the main vessel, and the inserted bypass stent graft is expanded. The branch vessel is occluded between the ostium of the bypass stent graft and the main vessel, and a main stent graft is inserted in the main vessel proximate the opening in the main vessel wall.

Abstract translation: 本发明提供一种提供血管内旁路的方法。 该方法包括以下步骤：通过导管将携带导丝的弹性针插入口附近，并将针延伸穿过分支血管壁。 该方法通过将针穿过血管外空间并将针插入主血管壁以创建开口来继续。 针缩回，将导丝留在原位。 沿着导丝插入旁路支架移植物以提供分支血管和主血管之间的通路，并且插入的旁路支架移植物扩张。 分支血管被封闭在旁路支架移植物的口和主血管之间，并且主支架移植物在主血管壁中的开口附近插入主血管。

公开(公告)号：US20050278013A1

公开(公告)日：2005-12-15

申请号：US10891397

申请日：2004-07-14

Applicant: Matthew Rust ,  Prema Ganesan ,  Curtis Hanson ,  Jack Chu

Inventor： Matthew Rust ,  Prema Ganesan ,  Curtis Hanson ,  Jack Chu

IPC: A61B17/00 ,  A61B17/12 ,  A61B17/34 ,  A61F2/02 ,  A61F2/06

CPC classification number: A61F2/07 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12118 ,  A61B17/12131 ,  A61B17/3403 ,  A61B2017/00252 ,  A61F2/06 ,  A61F2/064 ,  A61F2/89 ,  A61F2002/061 ,  A61F2002/072

Abstract: The invention provides a method of providing an endovascular bypass. The method includes the steps of inserting an elastic needle carrying a guidewire adjacent an ostium via a catheter and extending the needle through a branch vessel wall. The method continues by extending the needle through the extravascular space and inserting the needle through a main vessel wall to create an opening. The needle is retracted, leaving the guidewire in place. A bypass stent graft is inserted along the guidewire to provide a pathway between the branch vessel and the main vessel, and the inserted bypass stent graft is expanded. The branch vessel is occluded between the ostium of the bypass stent graft and the main vessel, and a main stent graft is inserted in the main vessel proximate the opening in the main vessel wall.

Abstract translation: 本发明提供一种提供血管内旁路的方法。 该方法包括以下步骤：通过导管将携带导丝的弹性针插入口附近，并将针延伸穿过分支血管壁。 该方法通过将针穿过血管外空间并将针插入主血管壁以创建开口来继续。 针缩回，将导丝留在原位。 沿着导丝插入旁路支架移植物以提供分支血管和主血管之间的通路，并且插入的旁路支架移植物扩张。 分支血管被封闭在旁路支架移植物的口和主血管之间，并且主支架移植物在主血管壁中的开口附近插入主血管。

公开(公告)号：US09144648B2

公开(公告)日：2015-09-29

申请号：US12299288

申请日：2007-05-02

Applicant: Paul R. Lesch, Jr. ,  Matthew Rust ,  Tom KraMer

Inventor： Paul R. Lesch, Jr. ,  Matthew Rust ,  Tom KraMer

IPC: A61M5/00 ,  A61M5/32 ,  A61M5/20 ,  A61M5/30 ,  A61M5/315 ,  A61M5/42 ,  A61M5/31

CPC classification number: A61M5/2033 ,  A61M5/30 ,  A61M5/31541 ,  A61M5/31553 ,  A61M5/31563 ,  A61M5/3158 ,  A61M5/31591 ,  A61M5/3202 ,  A61M5/326 ,  A61M5/425 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/3125

Abstract: An injector for injecting medicament in a patient. The injector includes a container comprising a fluid chamber containing a first volume of a medicament, and an injection conduit associated with the fluid chamber for defining a fluid pathway therefrom to inject the medicament from the fluid chamber through the injection conduit to an injection location. The injector also includes a firing mechanism associated with the fluid chamber for expelling the medicament from the fluid chamber through the injection conduit, and a volume-control mechanism operable to control a fraction of the first volume of medicament that is injected when the firing mechanism is actuated to inject the medicament.

Abstract translation: 一种用于在患者体内注射药物的注射器。 注射器包括容器，该容器包括容纳第一体积的药物的流体室，以及与流体室相关联的注射导管，用于限定其流体通道，以将药物从流体室通过注射导管注射到注射位置。 喷射器还包括与流体室相关联的用于从药液流经注射导管排出药物的击发机构，以及容积控制机构，其可操作以控制当所述发射机构为发射机构时所注射的第一体积药物的一部分 致动以注射药物。

公开(公告)号：US08771344B2

公开(公告)日：2014-07-08

申请号：US13967894

申请日：2013-08-15

Applicant: Don Tran ,  Nathan Wiemeyer ,  Susheel Deshmukh ,  Leonel Mendoza ,  Matthew Rust

Inventor： Don Tran ,  Nathan Wiemeyer ,  Susheel Deshmukh ,  Leonel Mendoza ,  Matthew Rust

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2250/0018 ,  A61F2250/0039

Abstract: A device for percutaneously repairing a heart valve of a patient including a self-expanding, stented prosthetic heart valve and a delivery system. The delivery system includes delivery sheath slidably receiving an inner shaft forming a coupling structure. A capsule of the delivery sheath includes a distal segment and a proximal segment. An outer diameter of the distal segment is greater than that of the proximal segment. An area moment of inertia of the distal segment can be greater than an area moment of inertia of the proximal segment. Regardless, an axial length of the distal segment is less than the axial length of the prosthesis. In a loaded state, the prosthesis engages the coupling structure and is compressively retained within the capsule. The capsule is unlikely to kink when traversing the patient's vasculature, such as when tracking around the aortic arch, promoting recapturing of the prosthesis.

Abstract translation: 一种用于经皮修复患者的心脏瓣膜的装置，包括自膨胀，支架假体心脏瓣膜和输送系统。 输送系统包括可滑动地接收形成联接结构的内轴的输送护套。 输送鞘的囊包括远端段和近端段。 远侧段的外径大于近端段的外径。 远侧段的面积惯性矩可以大于近端段的面积惯性矩。 无论如何，远端段的轴向长度小于假体的轴向长度。 在装载状态下，假体接合联接结构并被压缩地保持在胶囊内。 当穿过患者的脉管系统时，例如当跟踪主动脉弓周围时，胶囊不可能扭结，促进假体的重新捕获。

公开(公告)号：US20140005769A1

公开(公告)日：2014-01-02

申请号：US13967894

申请日：2013-08-15

Applicant: Don Tran ,  Nathan Wiemeyer ,  Susheel Deshmukh ,  Leonal Mendoza ,  Matthew Rust

Inventor： Don Tran ,  Nathan Wiemeyer ,  Susheel Deshmukh ,  Leonal Mendoza ,  Matthew Rust

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2250/0018 ,  A61F2250/0039

Abstract: A device for percutaneously repairing a heart valve of a patient including a self-expanding, stented prosthetic heart valve and a delivery system. The delivery system includes delivery sheath slidably receiving an inner shaft forming a coupling structure. A capsule of the delivery sheath includes a distal segment and a proximal segment. An outer diameter of the distal segment is greater than that of the proximal segment. An area moment of inertia of the distal segment can be greater than an area moment of inertia of the proximal segment. Regardless, an axial length of the distal segment is less than the axial length of the prosthesis. In a loaded state, the prosthesis engages the coupling structure and is compressively retained within the capsule. The capsule is unlikely to kink when traversing the patient's vasculature, such as when tracking around the aortic arch, promoting recapturing of the prosthesis.

Abstract translation: 一种用于经皮修复患者的心脏瓣膜的装置，包括自膨胀，支架假体心脏瓣膜和输送系统。 输送系统包括可滑动地接收形成联接结构的内轴的输送护套。 输送鞘的囊包括远端段和近端段。 远侧段的外径大于近端段的外径。 远侧段的面积惯性矩可以大于近端段的面积惯性矩。 无论如何，远端段的轴向长度小于假体的轴向长度。 在装载状态下，假体接合联接结构并被压缩地保持在胶囊内。 当穿过患者的脉管系统时，例如当跟踪主动脉弓周围时，胶囊不可能扭结，促进假体的重新捕获。

公开(公告)号：US08512400B2

公开(公告)日：2013-08-20

申请号：US12757111

申请日：2010-04-09

Applicant: Don Tran ,  Nathan Wiemeyer ,  Susheel Deshmukh ,  Leonal Mendoza ,  Matthew Rust

Inventor： Don Tran ,  Nathan Wiemeyer ,  Susheel Deshmukh ,  Leonal Mendoza ,  Matthew Rust

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2250/0018 ,  A61F2250/0039

Abstract: A device for percutaneously repairing a heart valve of a patient including a self-expanding, stented prosthetic heart valve and a delivery system. The delivery system includes delivery sheath slidably receiving an inner shaft forming a coupling structure. A capsule of the delivery sheath includes a distal segment and a proximal segment. An outer diameter of the distal segment is greater than that of the proximal segment. An area moment of inertia of the distal segment can be greater than an area moment of inertia of the proximal segment. Regardless, an axial length of the distal segment is less than the axial length of the prosthesis. In a loaded state, the prosthesis engages the coupling structure and is compressively retained within the capsule. The capsule is unlikely to kink when traversing the patient's vasculature, such as when tracking around the aortic arch, promoting recapturing of the prosthesis.

Abstract translation: 一种用于经皮修复患者的心脏瓣膜的装置，包括自膨胀，支架假体心脏瓣膜和输送系统。 输送系统包括可滑动地接收形成联接结构的内轴的输送护套。 输送鞘的囊包括远端段和近端段。 远侧段的外径大于近端段的外径。 远侧段的面积惯性矩可以大于近端段的面积惯性矩。 无论如何，远端段的轴向长度小于假体的轴向长度。 在装载状态下，假体接合联接结构并被压缩地保持在胶囊内。 当穿过患者的脉管系统时，例如当跟踪主动脉弓周围时，胶囊不可能扭结，促进假体的重新捕获。

公开(公告)号：US08376993B2

公开(公告)日：2013-02-19

申请号：US12536106

申请日：2009-08-05

Applicant: Janice L. Cox ,  Matthew Rust ,  Thomas E. KraMer ,  Peter Hoeft

Inventor： Janice L. Cox ,  Matthew Rust ,  Thomas E. KraMer ,  Peter Hoeft

IPC: A61M5/00 ,  A61M5/30

CPC classification number: A61M5/31593 ,  A61M5/24 ,  A61M5/3129 ,  A61M5/31541 ,  A61M5/31545 ,  A61M5/31566 ,  A61M5/3158 ,  A61M2005/2403 ,  A61M2005/2407

Abstract: A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.

Abstract translation: 公开了一种药物分配机构，其配置成从药物室喷射连续剂量的药物。 分配机构的一个实施例包括壳体和构造成从腔室喷出剂量的药剂的柱塞杆。 分配机构还包括致动机构，其包括与壳体相关联的触发器，并且具有相对于其的就绪和被击发位置。 触发器构造成用于由用户操作以便从准备位置到触发位置的大致轴向的计量运动中连续运动，在该位置触发器与柱塞杆相关联，以使柱塞杆弹出预定的一个剂量中的一个 体积和从点火位置到包括轴向旋转的就绪位置的复位运动，其中在复位运动期间触发器与柱塞杆脱离。