公开(公告)号：US20240074775A1

公开(公告)日：2024-03-07

申请号：US18261246

申请日：2021-10-06

Applicant: WOMEN'S AND CHILDREN'S LOCAL HEALTH NETWORK INC. ,  THE UNIVERSITY OF ADELAIDE

Inventor： Martin DONNELLEY ,  Alexandra MCCARRON ,  David PARSONS

IPC: A61B17/24 ,  A61K48/00

CPC classification number: A61B17/24 ,  A61K48/0075 ,  A61B2017/242

Abstract: The present disclosure relates to non-surgical methods for delivery of an agent to the respiratory system of a subject, methods of treatment using delivery of agents to the respiratory system, devices for delivery of agents to the respiratory system, and use of such devices to deliver agents to the respiratory system. In certain embodiments, the present disclosure provides a provide a non-surgical method of delivering an agent to the respiratory system of a subject. The method comprises in vivo perturbation of the airway surface in one or more parts of the respiratory system in the subject and exposing the perturbed surface of the airway to the agent, thereby delivering the agent to the respiratory system of the subject.

公开(公告)号：US20230310501A1

公开(公告)日：2023-10-05

申请号：US18110528

申请日：2023-02-16

Applicant: THE UNIVERSITY OF ADELAIDE

Inventor： Shaun Reuss Mccoll

IPC: A61K35/17 ,  A61P35/00 ,  C07K14/715 ,  C12N5/0783 ,  C12N15/86

CPC classification number: A61K35/17 ,  A61P35/00 ,  C07K14/7158 ,  C12N5/0636 ,  C12N15/86 ,  C12N2740/13043

Abstract: The present disclosure relates to methods and products for preventing and/or treating cancer, and in particular to methods, cells and products for preventing and/or treating cancer using adoptive immunotherapies. In certain embodiments, the present disclosure provides a method of treating a subject suffering from, or susceptible to, a cancer associated with chemokine expressing cells, the method comprising exposing the subject to T cells expressing a receptor to the chemokine and thereby treating the subject.

公开(公告)号：US11590075B2

公开(公告)日：2023-02-28

申请号：US16489115

申请日：2018-02-27

Applicant: The University of Adelaide

Inventor： Sarah Vreugde ,  Peter John Wormald

IPC: A61K9/06 ,  A61K31/4412 ,  A61K47/36 ,  A61K9/00 ,  A61L31/04 ,  A61L31/14 ,  A61L31/16 ,  A61P41/00

Abstract: The present disclosure relates to methods and products for reducing adhesions. In certain embodiments, the present disclosure provides a method of reducing adhesions in a subject, the method comprising exposing a region in the subject susceptible to formation of an adhesion to an agent having iron chelation and/or antioxidant activity, thereby reducing adhesions in the subject.

公开(公告)号：US20220373408A1

公开(公告)日：2022-11-24

申请号：US17767244

申请日：2020-10-08

Applicant: The University of Adelaide

Inventor： Stephen Christopher Warren-Smith ,  Heike Ebendorff-Heidepriem ,  Viet Linh Nguyen ,  Erik Peter Schartner

IPC: G01K11/3206 ,  G02B6/02

Abstract: A microstructured optical fiber sensor for sensing changes in a physical characteristic up to a predetermined temperature is disclosed. The sensor includes a microstructured optical fiber and a fiber Bragg grating formed in the microstructured optical fiber by generating a periodic modulation in the refractive index along a core region of the suspended core. The fiber Bragg grating is configured to produce a band reflection spectra including a fundamental mode and a plurality of higher order modes whose respective wavelengths vary in accordance with changes in the physical characteristic at the core region of the microstructured optical fiber. The microstructured optical fiber is configured to increase the confinement loss of the plurality of higher order modes of the band reflection spectra relative to the fundamental mode.

公开(公告)号：US20220216526A1

公开(公告)日：2022-07-07

申请号：US17601283

申请日：2020-04-03

Applicant: THE UNIVERSITY OF ADELAIDE

Inventor： Dongliang CHAO ,  Shi-Zhang QIAO

IPC: H01M10/36 ,  H01M10/26 ,  H01M4/80 ,  H01M4/66 ,  H01M4/24 ,  H01M4/50 ,  H01M4/42

Abstract: A novel energy storage battery system is described that includes a highly reversible electrolytic Zn—MnO2 system in which electrodeposition/electrolysis of Zn (anode side) and MnO2 (cathode side) couple is employed with a theoretical voltage approximately 2 V and energy density of approximately 409 Wh kg−1 providing superior durability and excellent energy densities.

公开(公告)号：US11299228B2

公开(公告)日：2022-04-12

申请号：US16319288

申请日：2017-07-21

Applicant: The University of Adelaide

Inventor： Richard Malcolm Kelso ,  Henry James Atkins ,  Shaun James Fitzgerald

IPC: B62K3/02 ,  B62J1/08 ,  B62K21/12 ,  B62K21/02 ,  B62K19/02 ,  B62J17/10

Abstract: The present disclosure relates to a bicycle frame and associated bicycle components, and to reducing the aerodynamic drag of these. In one aspect, there is provided an elongate structural member of a bicycle frame, the member comprising a lengthwise extending leading edge, the leading edge comprising at least a pair of forwardly extending protrusions spaced apart lengthwise therealong. In one form, the protrusions comprise tubercles, a series of which are spaced apart lengthwise along the leading edge, and which further extend to at least one side of the leading edge so as to transition into a chordwise extending rib.

公开(公告)号：US20210380497A1

公开(公告)日：2021-12-09

申请号：US17351458

申请日：2021-06-18

Applicant: THE UNIVERSITY OF ADELAIDE

Inventor： Dusan LOSIC ,  Shervin KABIRI ,  Michael MCLAUGHLIN ,  Diana TRAN ,  Ivan ANDELKOVIC

IPC: C05D9/02 ,  C05G5/12 ,  C05G5/30 ,  C05G3/40 ,  C05D9/00

Abstract: A new slow-release fertilizer is described that is formed by applying graphene oxide (GO) as a carrier for micronutrients such as copper (Cu) and zinc (Zn), in which the micronutrients are efficiently bonded with the functional groups at the surface and sides of the GO sheets due to their affinity to the unpaired oxygen atoms in the GO. The prepared Cu-graphene oxide (Cu-GO) and Zn-graphene oxide (Zn-GO) fertilizers showed a biphasic dissolution behaviour compared to commercial zinc sulphate (ZnSO4) and copper sulphate (CuSO4) fertilizer granules, displaying both fast- and slow-release micronutrient release.

公开(公告)号：US20210355385A1

公开(公告)日：2021-11-18

申请号：US17388742

申请日：2021-07-29

Applicant: The University of Adelaide

Inventor： Dusan LOSIC ,  Md Julker NINE ,  Diana N H TRAN

IPC: C09K21/02 ,  C08K3/38 ,  C01B32/192 ,  C08K3/04 ,  C01B32/19 ,  C09K21/06 ,  C08K3/22 ,  C08J7/05 ,  C08J7/06 ,  C09D5/18

Abstract: A method of improving fire retardant properties of a substrate includes providing the substrate with a graphene-based composite, wherein the graphene-based composite includes graphene-based material intercalated with inorganic metal hydrate.

公开(公告)号：US20200261440A1

公开(公告)日：2020-08-20

申请号：US16755328

申请日：2018-10-12

Applicant: THE UNIVERSITY OF QUEENSLAND ,  THE UNIVERSITY OF ADELAIDE ,  GRIFFITH UNIVERSITY

Inventor： Mark WALKER ,  Christopher MCDEVITT ,  Mark VON ITZSTEIN ,  Alastair MCEWAN

IPC: A61K31/473 ,  A61K45/06 ,  A61K38/12 ,  A61K33/30 ,  A61P31/04

Abstract: This invention relates to the use of zinc(II) salts in combination with a zinc ionophore to resensitize a previously resistant pathogenic bacteria to an antibiotic. Methods of restoring the sensitivity of a resistant pathogenic bacterium to an antibiotic comprising administering a zinc ionophore in combination with a zinc(II) salt and methods of treating a bacterial infection comprising administering a zinc ionophore in combination with a zinc (II) salt concurrently and/or sequentially with administration of a therapeutically effective amount of an antibiotic is also described.

公开(公告)号：US20180224163A1

公开(公告)日：2018-08-09

申请号：US15750297

申请日：2016-08-12

Applicant: The University of Adelaide

Inventor： Maziar Arjomandi ,  Graham Jerrold Nathan ,  Alfonso Chinnici ,  Zhao Tian

IPC: F24S60/00

Abstract: A solar receiver for exposing heat absorbing particles to concentrated solar radiation. The solar receiver includes a chamber having an aperture through which concentrated solar radiation can be received within the chamber. An inlet means provides for introducing an inflow including solar absorbing particles into the chamber. An outlet means provides for discharge of an outflow from the chamber. The inlet means communicates with the chamber for introduction of the inflow into a first section of the chamber in opposed relation the aperture. The outlet means communicates with a second section of the chamber disposed between the first section and the aperture, wherein fluid flow from the inlet means to the outlet means is exposed to concentrated solar radiation received within the chamber. The first section diverges in a direction towards the aperture, and the inlet means is configured to introduce the inflow tangentially into the divergent first section.