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公开(公告)号：US20140370073A1
公开(公告)日：2014-12-18
申请号：US14475379
申请日：2014-09-02
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yiwen Tang , Syed F.A. Hossainy , Andrew C. Tung , Stephen D. Pacetti
CPC classification number: A61L31/10 , A61L27/34 , A61L31/148 , A61L2420/06 , C08L67/04
Abstract: A medical article is disclosed, comprising a biologically degradable AB block copolymer and a biologically degradable polymer that is capable, at equilibrium and at room temperature, of absorbing less than about 5 mass % water.
Abstract translation: 公开了一种医疗用品，其包含生物降解性AB嵌段共聚物和生物可降解聚合物，其能够在平衡和室温下吸收小于约5质量％的水。
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公开(公告)号：US20140363563A1
公开(公告)日：2014-12-11
申请号：US14308412
申请日：2014-06-18
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F.A. Hossainy , Mikael Trollsas , Thierry Glauser , Yiwen Tang
CPC classification number: A61L31/10 , A61K38/08 , A61K38/39 , A61L27/227 , A61L27/34 , A61L27/54 , A61L29/085 , A61L31/047 , A61L31/16 , A61L2300/25 , A61L2420/02 , B05D3/007 , C07K14/001 , C08H1/00 , Y10T428/3154 , Y10T428/31909
Abstract: A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided.
Abstract translation: 提供了包含弹性蛋白五肽嵌段的共聚物以及制备和使用该共聚物的方法。
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Patent Agency Ranking
33.发明申请NANOPARTICLE LOADED ELECTROSPUN IMPLANTS OR COATINGS FOR DRUG RELEASE 审中-公开NANOPARTICLE LOADED ELECTROSPUN IMPLANTS或涂料用于药物释放公开(公告)号：US20140358217A1
公开(公告)日：2014-12-04
申请号：US14462476
申请日：2014-08-18
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： John Stankus , Syed F.A. Hossainy , Jinping Wan
IPC: A61F2/86
CPC classification number: A61F2/86 , A61L31/14 , B32B1/08 , D01D5/0069 , D01F1/10 , D04H1/728 , D04H1/76
Abstract: Medical devices, such as stents, including a fibrous layer including particles are disclosed. Methods of forming such medical devices using electrospinning are disclosed.
Abstract translation: 公开了包括包括颗粒的纤维层在内的医疗装置，例如支架。 公开了使用静电纺丝形成这种医疗装置的方法。
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公开(公告)号：US20140356519A1
公开(公告)日：2014-12-04
申请号：US14308444
申请日：2014-06-18
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F.A. Hossainy , Mikael Trollsas , Thierry Glauser , Yiwen Tang
IPC: A61L31/10
CPC classification number: A61L31/10 , A61K38/08 , A61K38/39 , A61L27/227 , A61L27/34 , A61L27/54 , A61L29/085 , A61L31/047 , A61L31/16 , A61L2300/25 , A61L2420/02 , B05D3/007 , C07K14/001 , C08H1/00 , Y10T428/3154 , Y10T428/31909
Abstract: A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided.
Abstract translation: 提供了包含弹性蛋白五肽嵌段的共聚物以及制备和使用该共聚物的方法。
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35.发明申请Coating Comprising an Amorphous Primer Layer and a Semi-Crystalline Reservoir Layer 审中-公开包括无定形底层和半晶体储层的涂层公开(公告)号：US20140178454A1
公开(公告)日：2014-06-26
申请号：US14109795
申请日：2013-12-17
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Florencia Lim , Mikael O. Trollsas , Syed F.A. Hossainy , Stephen D. Pacetti
CPC classification number: A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/604 , A61L2300/606 , Y10T24/258 , C08L67/04
Abstract: The present invention provides a coating comprising a reservoir layer comprising a semi-crystalline polymer and a primer layer comprising an amorphous polymer on an implantable device and methods of making and using the same.
Abstract translation: 本发明提供一种包含储存层的涂层，其包含半结晶聚合物和在可植入装置上包含无定形聚合物的底漆层及其制备和使用该涂层的方法。
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公开(公告)号：US20140037832A1
公开(公告)日：2014-02-06
申请号：US14053796
申请日：2013-10-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Florian N. Ludwig , Syed F.A. Hossainy , Srinivasan Sridharan , Carol Lee
CPC classification number: A61L31/10 , A61L27/34 , A61L27/50 , A61L27/54 , A61L2300/406 , A61L2300/41 , A61L2300/416 , A61L2300/606 , A61M31/002
Abstract: Methods are disclosed for controlling the morphology and the release-rate of active agent from coating layers for medical devices comprising a polymer matrix and one or more active agents. The methods comprise fixing the morphology or phase distribution of the active agent prior to removing solvent from the coating composition. The coating layers can be used for controlled the delivery of an active agent or a combination of active agents.
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37.发明申请公开(公告)号：US20130129814A1
公开(公告)日：2013-05-23
申请号：US13725525
申请日：2012-12-21
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Stephen D. Pacetti , Paul M. Consigny , Ronald W. Heil, JR. , Florian Niklas Ludwig , Dariush Davalian , Li Zhao , Irina Astafieva , Jinping Wan , Fozan El-Nounou , Katsuyuki Murase , Syed F.A. Hossainy , Rachel Bright , Jeffrey Ellis
IPC: A61M25/10
CPC classification number: A61M25/1002 , A61F2/82 , A61F2250/0067 , A61K31/27 , A61K31/44 , A61K31/56 , A61K31/66 , A61K38/1709 , A61L29/08 , A61L29/16 , A61L31/08 , A61L31/16 , A61L2300/112 , A61L2300/216 , A61L2300/252 , A61L2300/40 , A61L2300/41 , A61L2300/416 , A61L2300/606 , A61L2300/62 , A61M25/10 , A61M37/0015 , A61M2025/105 , A61M2025/1086 , A61M2037/0023 , A61M2037/0061 , A61M2210/12
Abstract: The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well.
Abstract translation: 本发明涉及用于治疗血管疾病的治疗剂的区域递送，其中区域递送是指将治疗有效量的治疗剂递送至血管的区域，该区域不仅包括受到损伤的组织而且包括非折磨组织 受影响组织的外围也是如此。
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