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公开(公告)号：US20080058885A1
公开(公告)日：2008-03-06
申请号：US11469018
申请日：2006-08-31
IPC分类号： A61N1/00
CPC分类号： A61N1/3627 , A61N1/36514 , A61N1/3704 , A61N1/37288 , A61N1/378
摘要： A sensor is located within the body of a subject, such as for capturing pacing pulses transmitted as part of cardiac therapy from an implanted cardiac function management device. Counted pulses may be used to derive the onset of pulmonary edema within the body through pulse characteristics such as frequency and amplitude. The sensor may be anchored within mediastinal pleura or the airway of the body with the ability to communicate wirelessly to one or more other medical devices, such as an implanted cardiac function management device. It may also adjust transmission of the communication to discriminate among multiple sensors. Methods of use are also described.
摘要翻译： 传感器位于受试者的体内，例如用于从植入的心脏功能管理装置捕获作为心脏治疗的一部分传输的起搏脉冲。 计数脉冲可用于通过诸如频率和幅度的脉冲特征来导出身体内肺水肿的发作。 传感器可以锚定在纵膈胸膜或身体的气道中，其能够无线地通信到一个或多个其它医疗装置，例如植入的心脏功能管理装置。 它还可以调整通信的传输以区分多个传感器。 还描述了使用方法。
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公开(公告)号：US20070270707A1
公开(公告)日：2007-11-22
申请号：US11419120
申请日：2006-05-18
申请人： Andres Belalcazar
发明人： Andres Belalcazar
IPC分类号： A61B5/05
CPC分类号： A61B5/0537 , A61N1/08 , G01G19/50 , G01G23/3735 , G01G23/3742
摘要： Changes in an amount of fluid in a region of a subject, such as the lung(s), may be detected by internally injecting a current through the region, detecting a resulting voltage at an upper and lower body portion, and calculating an impedance value using knowledge of the injected current and resulting voltage. Alternatively, the amount of fluid in the region may be found by internally applying a voltage of known or controllable value (thereby, injecting a current), detecting a resulting voltage at the upper and lower body portions, and calculating a fluid indicative signal using the resulting voltage or using a product of the resulting voltage and the injected current (i.e., power). A method for performing such measurements includes, among other things, injecting a current between first and second internal electrodes and measuring a resulting voltage between first and second external electrodes contacting the subject's upper and lower body portions.
摘要翻译： 可以通过在该区域内部注入电流来检测受试者（例如肺）区域中的流体量的变化，检测上身和下身部分处的所得电压，并计算阻抗值 使用注入电流和产生的电压的知识。 或者，可以通过在内部施加已知或可控值的电压（从而注入电流），检测上部和下部主体部分处产生的电压，并使用该方法计算流体指示信号来发现该区域中的流体量 产生的电压或使用所产生的电压和注入电流（即功率）的乘积。 用于执行这种测量的方法包括在第一和第二内部电极之间注入电流并测量在接触受检者的上部和下部本体部分的第一和第二外部电极之间产生的电压。
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公开(公告)号：US20070203420A1
公开(公告)日：2007-08-30
申请号：US11626329
申请日：2007-01-23
IPC分类号： A61B5/04
CPC分类号： A61N1/3627 , A61B5/0031 , A61B5/04011
摘要： An implantable medical device includes a voltage measurement circuit to measure a potential difference between implanted electrodes in a thorax of a living being, the potential difference resulting from an electrical P-wave cardiac signal. The implantable medical device also includes a processing unit to calculate a vector corresponding to the P-wave cardiac signal, the vector comprising a magnitude and a direction, and derived from measured potential differences and orientations defined by locations of the implanted electrodes. The implantable medical device further includes a monitoring unit to track a rotation of the vector corresponding to the P-wave cardiac signal. In various implementations, the monitoring unit may use the rotation to detect an inter-atrial block condition.
摘要翻译： 可植入医疗装置包括电压测量电路，用于测量生物胸部中植入的电极之间的电位差，由电P波心脏信号产生的电位差。 可植入医疗装置还包括处理单元，用于计算对应于P波心脏信号的矢量，所述矢量包括幅度和方向，并且从测量的电位差和由注入电极的位置限定的取向导出。 可植入医疗装置还包括监测单元，用于跟踪对应于P波心脏信号的矢量的旋转。 在各种实现中，监视单元可以使用旋转来检测心房间块状况。
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34.发明申请Pathology assessment with impedance measurements using convergent bioelectric lead fields 有权使用收敛生物电导领域进行阻抗测量的病理学评估公开(公告)号：US20060184060A1
公开(公告)日：2006-08-17
申请号：US11058123
申请日：2005-02-15
IPC分类号： A61B5/05
CPC分类号： A61B5/416 , A61B5/0537 , A61B5/4519
摘要： A method and apparatus for measuring impedance for pathology assessment in a living being using convergent bioelectric lead fields is disclosed, including injecting a current between first and second electrodes implanted in a body of a living being, where the first and second electrodes define a first electric lead field oriented between the first and second electrodes. A potential difference is measured between third and fourth electrodes implanted in the body, where the potential difference results from the current injected between the first and second electrodes. The third and fourth electrodes define a second electric lead field oriented between the third and fourth electrodes. The first and second electric lead fields converge near an assessment site within the body, but are substantially separated otherwise. An impedance value is calculated based on the potential difference and the current injection, and is used to assess a pathology near the assessment site.
摘要翻译： 公开了一种用于测量在使用会聚生物电场领域的生物中的病理学评估阻抗的方法和装置，包括在植入生物体内的第一和第二电极之间注入电流，其中第一和第二电极限定第一电 引线场定向在第一和第二电极之间。 在植入体内的第三和第四电极之间测量电位差，其中电位差由注入在第一和第二电极之间的电流产生。 第三和第四电极限定了定向在第三和第四电极之间的第二电引线场。 第一和第二电引线场在体内的评估位点附近收敛，但是基本上彼此分离。 基于电位差和电流注入计算阻抗值，并用于评估评估点附近的病理学。
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35.发明授权Systems and methods for placing electronic devices into “cautery-safe” mode 有权将电子设备放置在“烧烤安全”模式中的系统和方法公开(公告)号：US08755902B2
公开(公告)日：2014-06-17
申请号：US12793374
申请日：2010-06-03
申请人： Keith Lurie , Barbara S. Gold , David Benditt , Andres Belalcazar
发明人： Keith Lurie , Barbara S. Gold , David Benditt , Andres Belalcazar
IPC分类号： A61N1/37
CPC分类号： A61N1/37264 , A61N1/3688 , A61N1/37 , A61N1/37247 , A61N1/3931
摘要： A method and device to enable a medical or surgical procedure using electro-cautery on a patient with an implantable device in a cautery-safe mode of operation. In one embodiment, the invention provides an electronic implantable device programmer having a computer processor, and a display screen configured to display information based on signals from the computer processor. The programmer also includes an input device, and a wireless transmitter controlled by the computer processor. The programmer display and input give the operator the option of programming an implanted electronic device in a cautery-safe mode. With this input, from the operator, instructions are provided in the programmer to transmit a signal from the wireless transmission device to the implanted electronic device to program the electronic device to be in a dedicated bipolar mode where electrical noise produced when operating an electro-cautery device during and medical/surgical procedure does not interfere with operation of the electronic device.
摘要翻译： 一种方法和装置，其使得能够在具有安全操作操作的可植入装置的患者身上使用电烙术进行医疗或外科手术。 在一个实施例中，本发明提供一种具有计算机处理器的电子可植入装置编程器，以及配置为基于来自计算机处理器的信号显示信息的显示屏。 编程器还包括输入设备和由计算机处理器控制的无线发射器。 编程器显示和输入使操作者可以选择在烧焦安全模式下对植入的电子设备进行编程。 通过该输入，从操作者处，在编程器中提供指令以将信号从无线传输设备发送到植入的电子设备，以将电子设备编程为专用的双极模式，其中在操作电烙铁时产生电噪声 设备在医疗/外科手术过程中不影响电子设备的操作。
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公开(公告)号：US08311630B2
公开(公告)日：2012-11-13
申请号：US13229948
申请日：2011-09-12
IPC分类号： A61N1/365
CPC分类号： A61N1/3627 , A61N1/36521 , A61N1/36535 , A61N1/36542 , A61N1/36564 , A61N1/3688
摘要： An implantable pacing device for delivering ventricular pacing may be configured to intermittently reduce the AVD interval for beneficial effect in patients with compromised ventricular function (e.g., HF patients and post-MI patients). The AVD interval may be reduced in an AVD reduction mode, by shortening the AVD in an atrial triggered ventricular pacing mode or by switching to a non-atrial triggered ventricular pacing mode (e.g., VVI) and delivering paces at a rate above the intrinsic rate. The physiological effects of AVD reduction may be either positive or negative on cardiac output, depending upon the individual patient.
摘要翻译： 用于输送心室起搏的可植入起搏装置可以被配置为间歇地减小AVD间隔，以在患有心室功能受损的患者（例如，HF患者和MI后患者）中产生有益效果。 通过在心房触发的心室起搏模式中缩短AVD或者通过切换到非心房触发的心室起搏模式（例如，VVI）并以高于内在速率的速率递送步进，AVD间期可以减小AVD减小模式 。 取决于个体患者，AVD减少的生理作用可能是心输出量的正或负。
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公开(公告)号：US08096954B2
公开(公告)日：2012-01-17
申请号：US11564637
申请日：2006-11-29
申请人： Jeffrey E. Stahmann , Krzysztof Z. Siejko , Carlos Haro , Abhilash Patangay , Gerrard M. Carlson , Andres Belalcazar
发明人： Jeffrey E. Stahmann , Krzysztof Z. Siejko , Carlos Haro , Abhilash Patangay , Gerrard M. Carlson , Andres Belalcazar
IPC分类号： A61B5/02
CPC分类号： A61N1/36514 , A61B5/0031 , A61B5/021 , A61B5/024 , A61B5/053 , A61B5/08 , A61B5/0816 , A61B5/1116 , A61B5/4806 , A61B5/686 , A61B5/7275 , A61B7/04 , A61N1/36578
摘要： A system and method to sense heart sounds with one or more implantable medical devices according to one or more parameters. The system alters one or more of the parameters as a function of one or more triggering events. The system then senses heart sounds with the one or more implantable medical devices according to at least the one or more altered parameters.
摘要翻译： 根据一个或多个参数用一个或多个可植入医疗装置感测心脏声音的系统和方法。 系统根据一个或多个触发事件改变一个或多个参数。 该系统然后根据至少一个或多个改变的参数用一个或多个可植入医疗装置感测心脏声音。
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公开(公告)号：US08095207B2
公开(公告)日：2012-01-10
申请号：US11626329
申请日：2007-01-23
IPC分类号： A61B5/0402
CPC分类号： A61N1/3627 , A61B5/0031 , A61B5/04011
摘要： An implantable medical device includes a voltage measurement circuit to measure a potential difference between implanted electrodes in a thorax of a living being, the potential difference resulting from an electrical P-wave cardiac signal. The implantable medical device also includes a processing unit to calculate a vector corresponding to the P-wave cardiac signal, the vector comprising a magnitude and a direction, and derived from measured potential differences and orientations defined by locations of the implanted electrodes. The implantable medical device further includes a monitoring unit to track a rotation of the vector corresponding to the P-wave cardiac signal. In various implementations, the monitoring unit may use the rotation to detect an inter-atrial block condition.
摘要翻译： 可植入医疗装置包括电压测量电路，用于测量生物胸部中植入的电极之间的电位差，由电P波心脏信号产生的电位差。 可植入医疗装置还包括处理单元，用于计算对应于P波心脏信号的矢量，所述矢量包括幅度和方向，并且从测量的电位差和由注入电极的位置定义的取向导出。 可植入医疗装置还包括监测单元，用于跟踪对应于P波心脏信号的矢量的旋转。 在各种实现中，监视单元可以使用旋转来检测心房间块状况。
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公开(公告)号：US08019416B2
公开(公告)日：2011-09-13
申请号：US11615383
申请日：2006-12-22
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61N1/36521 , A61N1/36535 , A61N1/36542 , A61N1/36564 , A61N1/3688
摘要： An implantable pacing device for delivering ventricular pacing may be configured to intermittently reduce the AVD interval for beneficial effect in patients with compromised ventricular function (e.g., HF patients and post-MI patients). The AVD interval may be reduced in an AVD reduction mode, by shortening the AVD in an atrial triggered ventricular pacing mode or by switching to a non-atrial triggered ventricular pacing mode (e.g., VVI) and delivering paces at a rate above the intrinsic rate. The physiological effects of AVD reduction may be either positive or negative on cardiac output, depending upon the individual patient.
摘要翻译： 用于输送心室起搏的可植入起搏装置可以被配置为间歇地减小AVD间隔，以在患有心室功能受损的患者（例如，HF患者和MI后患者）中产生有益效果。 通过在心房触发的心室起搏模式中缩短AVD或者通过切换到非心房触发的心室起搏模式（例如，VVI）并以高于内在速率的速率递送步进，AVD间期可以减小AVD减小模式 。 取决于个体患者，AVD减少的生理作用可能是心输出量的正或负。
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公开(公告)号：US07860567B2
公开(公告)日：2010-12-28
申请号：US11469018
申请日：2006-08-31
IPC分类号： A61N1/08
CPC分类号： A61N1/3627 , A61N1/36514 , A61N1/3704 , A61N1/37288 , A61N1/378
摘要： A sensor is located within the body of a subject, such as for capturing pacing pulses transmitted as part of cardiac therapy from an implanted cardiac function management device. Counted pulses may be used to derive the onset of pulmonary edema within the body through pulse characteristics such as frequency and amplitude. The sensor may be anchored within mediastinal pleura or the airway of the body with the ability to communicate wirelessly to one or more other medical devices, such as an implanted cardiac function management device. It may also adjust transmission of the communication to discriminate among multiple sensors. Methods of use are also described.
摘要翻译： 传感器位于受试者的体内，例如用于从植入的心脏功能管理装置捕获作为心脏治疗的一部分传输的起搏脉冲。 计数脉冲可用于通过诸如频率和幅度的脉冲特征来导出身体内肺水肿的发作。 传感器可以锚定在纵膈胸膜或身体的气道中，其能够无线地通信到一个或多个其它医疗装置，例如植入的心脏功能管理装置。 它还可以调整通信的传输以区分多个传感器。 还描述了使用方法。
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